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SHP2 ablation mitigates osteoarthritic cartilage degeneration by promoting chondrocyte anabolism through SOX9.
- Published in:
- FASEB Journal, 2024, v. 38, n. 17, p. 1, doi. 10.1096/fj.202400642R
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- Publication type:
- Article
Polarizing Activity in Early Limb Cartilaginous Condensations.
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- Annals of the New York Academy of Sciences, 1996, v. 785, n. 1, p. 281, doi. 10.1111/j.1749-6632.1996.tb56284.x
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- Publication type:
- Article
Retinoid Agonists in the Targeting of Heterotopic Ossification.
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- Cells (2073-4409), 2021, v. 10, n. 11, p. 3245, doi. 10.3390/cells10113245
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- Publication type:
- Article
Retinoic acid is a major regulator of chondrocyte maturation and matrix mineralization.
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- Microscopy Research & Technique, 1994, v. 28, n. 6, p. 483, doi. 10.1002/jemt.1070280604
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- Publication type:
- Article
Primary Cilia Direct Murine Articular Cartilage Tidemark Patterning Through Hedgehog Signaling and Ambulatory Load.
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- Journal of Bone & Mineral Research, 2022, v. 37, n. 6, p. 1097, doi. 10.1002/jbmr.4506
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- Publication type:
- Article
Premature Growth Plate Closure Caused by a Hedgehog Cancer Drug Is Preventable by Co‐Administration of a Retinoid Antagonist in Mice.
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- Journal of Bone & Mineral Research, 2021, v. 36, n. 7, p. 1387, doi. 10.1002/jbmr.4291
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- Publication type:
- Article
Epiprofin Regulates Enamel Formation and Tooth Morphogenesis by Controlling Epithelial-Mesenchymal Interactions During Tooth Development.
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- Journal of Bone & Mineral Research, 2017, v. 32, n. 3, p. 601, doi. 10.1002/jbmr.3024
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- Publication type:
- Article
Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1<sup>R206H</sup> Fibrodysplasia Ossificans Progressiva (FOP) Mutation.
- Published in:
- 2016
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- Publication type:
- Other
Expression of syndecan-3 and tenascin-C: Possible involvement in periosteum development.
- Published in:
- Journal of Orthopaedic Research, 1996, v. 14, n. 3, p. 403, doi. 10.1002/jor.1100140310
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- Publication type:
- Article
Regulation of chondrocyte maturation by fibroblast growth factor-2 and parathyroid hormone.
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- Journal of Orthopaedic Research, 1995, v. 13, n. 6, p. 838, doi. 10.1002/jor.1100130606
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- Publication type:
- Article
GRK2, a novel regulator of skeletal development.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.L7919
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- Publication type:
- Article
Hox11 paralogous genes are required for formation of wrist and ankle joints and articular surface organization.
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- Annals of the New York Academy of Sciences, 2010, v. 1192, n. 1, p. 307, doi. 10.1111/j.1749-6632.2009.05234.x
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- Publication type:
- Article
Synovial Joint Formation during Mouse Limb Skeletogenesis.
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- Annals of the New York Academy of Sciences, 2007, v. 1116, p. 100, doi. 10.1196/annals.1402.063
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- Publication type:
- Article
Cellular and Molecular Mechanisms of Synovial Joint and Articular Cartilage Formation.
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- Annals of the New York Academy of Sciences, 2006, v. 1068, n. 1, p. 74, doi. 10.1196/annals.1346.010
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- Publication type:
- Article
Osteoarthritis and chronic pain: Interleukin-6 as a common denominator and therapeutic target.
- Published in:
- Science Signaling, 2022, v. 15, n. 744, p. 1, doi. 10.1126/scisignal.add3702
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- Publication type:
- Article
Activin A promotes the development of acquired heterotopic ossification and is an effective target for disease attenuation in mice.
- Published in:
- Science Signaling, 2021, v. 14, n. 669, p. 1, doi. 10.1126/scisignal.abd0536
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- Publication type:
- Article
Articular Cartilage Endurance and Resistance to Osteoarthritic Changes Require Transcription Factor Erg.
- Published in:
- Arthritis & Rheumatology, 2015, v. 67, n. 10, p. 2679, doi. 10.1002/art.39243
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- Publication type:
- Article
Comment on ’Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity’.
- Published in:
- eLife, 2019, p. 1, doi. 10.7554/eLife.43173.001
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- Publication type:
- Article
Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop.
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- Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.732728
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- Publication type:
- Article
Hereditary Multiple Exostoses: New Insights into Pathogenesis, Clinical Complications, and Potential Treatments.
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- Current Osteoporosis Reports, 2017, v. 15, n. 3, p. 142, doi. 10.1007/s11914-017-0355-2
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- Publication type:
- Article
Articular Cartilage: Structural and Developmental Intricacies and Questions.
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- Current Osteoporosis Reports, 2015, v. 13, n. 6, p. 407, doi. 10.1007/s11914-015-0290-z
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- Publication type:
- Article
Retinoid Signaling Regulates CTGF Expression in Hypertrophic Chondrocytes With Differential Involvement of MAP Kinases.
- Published in:
- Journal of Bone & Mineral Research, 2005, v. 20, n. 5, p. 867, doi. 10.1359/JBMR.041235
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- Publication type:
- Article
Antiangiogenic Treatment Delays Chondrocyte Maturation and Bone Formation During Limb Skeletogenesis.
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- Journal of Bone & Mineral Research, 2002, v. 17, n. 1, p. 56, doi. 10.1359/jbmr.2002.17.1.56
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- Publication type:
- Article
Activation of Transforming Growth Factor β in Chondrocytes Undergoing Endochondral Ossification.
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- Journal of Bone & Mineral Research, 2001, v. 16, n. 12, p. 2339, doi. 10.1359/jbmr.2001.16.12.2339
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- Publication type:
- Article
Hedgehog Proteins Stimulate Chondrogenic Cell Differentiation and Cartilage Formation.
- Published in:
- Journal of Bone & Mineral Research, 2000, v. 15, n. 9, p. 1659, doi. 10.1359/jbmr.2000.15.9.1659
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- Publication type:
- Article
Transient Chondrogenic Phase in the Intramembranous Pathway During Normal Skeletal Development.
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- Journal of Bone & Mineral Research, 2000, v. 15, n. 3, p. 522, doi. 10.1359/jbmr.2000.15.3.522
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- Publication type:
- Article
Articular Chondrocytes Produce Factors That Inhibit Maturation of Sternal Chondrocytes in Serum-Free Agarose Cultures: A TGF-β Independent Process.
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- Journal of Bone & Mineral Research, 1997, v. 12, n. 9, p. 1368, doi. 10.1359/jbmr.1997.12.9.1368
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- Publication type:
- Article
Involvement of α5β1 Integrin in Matrix Interactions and Proliferation of Chondrocytes.
- Published in:
- Journal of Bone & Mineral Research, 1997, v. 12, n. 7, p. 1124, doi. 10.1359/jbmr.1997.12.7.1124
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- Publication type:
- Article
Retinoic acid induces a shift in the energetic state of hypertrophic chondrocytes.
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- Journal of Bone & Mineral Research, 1994, v. 9, n. 8, p. 1229, doi. 10.1002/jbmr.5650090813
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- Publication type:
- Article
Palovarotene Action Against Heterotopic Ossification Includes a Reduction of Local Participating Activin A‐Expressing Cell Populations.
- Published in:
- JBMR Plus, 2023, v. 7, n. 12, p. 1, doi. 10.1002/jbm4.10821
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- Publication type:
- Article
JBMRPlus: Special Issue on Rare Bone Diseases 2019.
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- JBMR Plus, 2019, v. 3, n. 8, p. N.PAG, doi. 10.1002/jbm4.10218
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- Publication type:
- Article
Mechanistic and Therapeutic Advances in Rare Skeletal Diseases Meeting, September 26–27, 2018: A Meeting in Affiliation With the American Society for Bone and Mineral Research (ASBMR).
- Published in:
- JBMR Plus, 2019, v. 3, p. S1, doi. 10.1002/jbm4.10136
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- Publication type:
- Article
Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses.
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- Journal of Orthopaedic Research, 2022, v. 40, n. 10, p. 2391, doi. 10.1002/jor.25260
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- Publication type:
- Article
Genetic and pharmacological inhibition of retinoic acid receptor γ function promotes endochondral bone formation.
- Published in:
- Journal of Orthopaedic Research, 2017, v. 35, n. 5, p. 1096, doi. 10.1002/jor.23347
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- Publication type:
- Article
Distribution of slow-cycling cells in epiphyseal cartilage and requirement of β-catenin signaling for their maintenance in growth plate.
- Published in:
- Journal of Orthopaedic Research, 2014, v. 32, n. 5, p. 661, doi. 10.1002/jor.22583
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- Publication type:
- Article
Inhibition of ectopic bone formation by a selective retinoic acid receptor α-agonist: A new therapy for heterotopic ossification?
- Published in:
- Journal of Orthopaedic Research, 2010, v. 28, n. 2, p. 271, doi. 10.1002/jor.20985
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- Publication type:
- Article
Regulating Mechanotransduction in Three Dimensions using Sub‐Cellular Scale, Crosslinkable Fibers of Controlled Diameter, Stiffness, and Alignment.
- Published in:
- Advanced Functional Materials, 2019, v. 29, n. 18, p. N.PAG, doi. 10.1002/adfm.201808967
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- Publication type:
- Article
Elevated inflammatory gene expression in intervertebral disc tissues in mice with ADAM8 inactivated.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-81495-y
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- Publication type:
- Article
Adenine nucleotide metabolism by chondrocytes in vitro: Role of ATP in chondrocyte maturation and matrix mineralization.
- Published in:
- Journal of Cellular Physiology, 1995, v. 165, n. 3, p. 468, doi. 10.1002/jcp.1041650304
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- Publication type:
- Article
Human and mouse activin genes: Divergent expression of activin A protein variants and identification of a novel heparan sulfate-binding domain in activin B.
- Published in:
- PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0229254
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- Publication type:
- Article
Identification and characterization of a novel heparan sulfate-binding domain in Activin A longest variants and implications for function.
- Published in:
- PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0222784
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- Publication type:
- Article
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-? agonists.
- Published in:
- Nature Medicine, 2012, v. 18, n. 10, p. 1592, doi. 10.1038/nm1012-1592b
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- Publication type:
- Article
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists.
- Published in:
- Nature Medicine, 2011, v. 17, n. 4, p. 454, doi. 10.1038/nm.2334
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- Publication type:
- Article
Hypertrophic Chondrocytes.
- Published in:
- Annals of the New York Academy of Sciences, 1990, v. 599, n. 1, p. 45, doi. 10.1111/j.1749-6632.1990.tb42363.x
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- Publication type:
- Article
Collagen Synthesis in Virus-transformed Cellsa.
- Published in:
- Annals of the New York Academy of Sciences, 1985, v. 460, n. 1, p. 202, doi. 10.1111/j.1749-6632.1985.tb51168.x
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- Publication type:
- Article
HhAntag, a Hedgehog Signaling Antagonist, Suppresses Chondrogenesis and Modulates Canonical and Non-Canonical BMP Signaling.
- Published in:
- Journal of Cellular Physiology, 2016, v. 231, n. 5, p. 1033, doi. 10.1002/jcp.25192
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- Publication type:
- Article
Heparan sulfate in skeletal development, growth, and pathology: The case of hereditary multiple exostoses.
- Published in:
- Developmental Dynamics, 2013, v. 242, n. 9, p. 1021, doi. 10.1002/dvdy.24010
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- Publication type:
- Article
Shop talk: Sugars, bones, and a disease called multiple hereditary exostoses.
- Published in:
- Developmental Dynamics, 2010, v. 239, n. 6, p. 1901, doi. 10.1002/dvdy.22290
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- Publication type:
- Article
Temporomandibular joint formation and condyle growth require Indian hedgehog signaling.
- Published in:
- Developmental Dynamics, 2007, v. 236, n. 2, p. 426, doi. 10.1002/dvdy.21036
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- Publication type:
- Article
Expression and roles of connective tissue growth factor in Meckel's cartilage development.
- Published in:
- Developmental Dynamics, 2004, v. 231, n. 1, p. 136
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- Publication type:
- Article