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A review: molecular aberrations within Hippo signaling in bone and soft-tissue sarcomas.
Published in:
Frontiers in Oncology, 2015, p. 1, doi. 10.3389/fonc.2015.00190
By:
- Deel, Michael D.;
- Li, Jenny J.;
- Crose, Lisa E. S.;
- Linardic, Corinne M.;
- Orentas, Rimas J.;
- Hettmer, Simone
Publication type:
Article
Bioinformatic description of immunotherapy targets for pediatric T-cell leukemia and the impact of normal gene sets used for comparison.
Published in:
Frontiers in Oncology, 2014, v. 4, p. 1, doi. 10.3389/fonc.2014.00134
By:
- Orentas, Rimas J.;
- Nordlund, Jessica;
- He, Jianbin;
- Sindiri, Sivasish;
- Mackall, Crystal;
- Fry, Terry J.;
- Khan, Javed
Publication type:
Article
Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients.
Published in:
Frontiers in Oncology, 2013, v. 3, p. 1, doi. 10.3389/fonc.2013.00017
By:
- Lehrnbecher, Thomas;
- Schmidt, Stanislaw;
- Tramsen, Lars;
- Klingebiel, Thomas;
- Meisel, Roland;
- Orentas, Rimas J.
Publication type:
Article
Identification of cell surface proteins as potential immunotherapy targets in 12 pediatric cancers.
Published in:
Frontiers in Oncology, 2012, v. 2, p. 1, doi. 10.3389/fonc.2012.00194
By:
- Orentas, Rimas J.;
- Yang, James J.;
- Xinyu Wen;
- Wei, Jun S.;
- Mackall, Crystal L.;
- Khan, Javed
Publication type:
Article
Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD22.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.869825
By:
- Sun, Zehua;
- Li, Wei;
- Mellors, John W.;
- Orentas, Rimas;
- Dimitrov, Dimiter S.
Publication type:
Article
Bryostatin Activates CAR T-Cell Antigen-Non-Specific Killing (CTAK), and CAR-T NK-Like Killing for Pre-B ALL, While Blocking Cytolysis of a Burkitt Lymphoma Cell Line.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.825364
By:
- Wang, Lingyan;
- Zhang, Yue;
- Anderson, Eden;
- Lamble, Adam;
- Orentas, Rimas J.
Publication type:
Article
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.
Published in:
Nature Medicine, 2015, v. 21, n. 6, p. 581, doi. 10.1038/nm.3838
By:
- Long, Adrienne H;
- Haso, Waleed M;
- Shern, Jack F;
- Wanhainen, Kelsey M;
- Murgai, Meera;
- Ingaramo, Maria;
- Smith, Jillian P;
- Walker, Alec J;
- Kohler, M Eric;
- Venkateshwara, Vikas R;
- Kaplan, Rosandra N;
- Patterson, George H;
- Fry, Terry J;
- Orentas, Rimas J;
- Mackall, Crystal L
Publication type:
Article
Correction to: Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.
Published in:
2018
By:
- Moore, Tamson;
- Wagner, Courtney Regan;
- Scurti, Gina M.;
- Hutchens, Kelli A.;
- Godellas, Constantine;
- Clark, Ann Lau;
- Kolawole, Elizabeth Motunrayo;
- Hellman, Lance M.;
- Singh, Nishant K.;
- Huyke, Fernando A.;
- Wang, Siao-Yi;
- Calabrese, Kelly M.;
- Embree, Heather D.;
- Orentas, Rimas;
- Shirai, Keisuke;
- Dellacecca, Emilia;
- Garrett-Mayer, Elizabeth;
- Li, Mingli;
- Eby, Jonathan M.;
- Stiff, Patrick J.
Publication type:
Correction Notice
Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.
Published in:
Cancer Immunology, Immunotherapy, 2018, v. 67, n. 2, p. 311, doi. 10.1007/s00262-017-2073-0
By:
- Moore, Tamson;
- Wagner, Courtney Regan;
- Scurti, Gina M.;
- Hutchens, Kelli A.;
- Godellas, Constantine;
- Clark, Ann Lau;
- Kolawole, Elizabeth Motunrayo;
- Hellman, Lance M.;
- Singh, Nishant K.;
- Huyke, Fernando A.;
- Wang, Siao-Yi;
- Calabrese, Kelly M.;
- Embree, Heather D.;
- Orentas, Rimas;
- Shirai, Keisuke;
- Dellacecca, Emilia;
- Garrett-Mayer, Elizabeth;
- Li, Mingli;
- Eby, Jonathan M.;
- Stiff, Patrick J.
Publication type:
Article
CD34-based enrichment of genetically engineered human T cells for clinical use results in dramatically enhanced tumor targeting.
Published in:
Cancer Immunology, Immunotherapy, 2010, v. 59, n. 6, p. 851, doi. 10.1007/s00262-009-0810-8
By:
- Norell, Håkan;
- Yi Zhang;
- McCracken, James;
- da Palma, Telma Martins;
- Lesher, Aaron;
- Yueying Liu;
- Roszkowski, Jeffrey J.;
- Temple, Anquanette;
- Callender, Glenda G.;
- Clay, Timothy;
- Orentas, Rimas;
- Guevara-Patiño, José;
- Nishimura, Michael I.
Publication type:
Article
Monitoring and modulation of Epstein–Barr virus loads in pediatric transplant patients.
Published in:
Pediatric Transplantation, 2003, v. 7, n. 4, p. 305, doi. 10.1034/j.1399-3046.2003.00090.x
By:
- Orentas, Rimas J.;
- Schauer, Dennis W.;
- Ellis, Frederick W.;
- Walczak, Joanna;
- Casper, James T.;
- Margolis, David A.
Publication type:
Article
Corrigendum: A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy.
Published in:
2019
By:
- Bari, Rafijul;
- Granzin, Markus;
- Tsang, Kam Sze;
- Roy, Andre;
- Krueger, Winfried;
- Orentas, Rimas;
- Schneider, Dina;
- Pfeifer, Rita;
- Moeker, Nina;
- Verhoeyen, Els;
- Dropulic, Boro;
- Leung, Wing
Publication type:
Correction Notice
A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02001
By:
- Bari, Rafijul;
- Granzin, Markus;
- Tsang, Kam Sze;
- Roy, Andre;
- Krueger, Winfried;
- Orentas, Rimas;
- Pfeifer, Rita;
- Moeker, Nina;
- Verhoeyen, Els;
- Dropulic, Boro;
- Leung, Wing
Publication type:
Article
CD19 CAR T cell product and disease attributes predict leukemia remission durability.
Published in:
2019
By:
- Finney, Olivia C.;
- Brakke, Hannah;
- Rawlings-Rhea, Stephanie;
- Hicks, Roxana;
- Doolittle, Danielle;
- Lopez, Marisa;
- Futrell, Ben;
- Orentas, Rimas J.;
- Daniel Li;
- Gardner, Rebecca;
- Jensen, Michael C.;
- Brakke, Hannah M;
- Futrell, Robert B;
- Li, Daniel;
- Gardner, Rebecca A
Publication type:
journal article
Paired expression analysis of Tumor cell surface antigens.
Published in:
Frontiers in Oncology, 2017, p. 1, doi. 10.3389/fonc.2017.00173
By:
- Orentas, Rimas J.;
- Sindiri, Sivasish;
- Duris, Christine;
- Xinyu Wen;
- Jianbin He;
- Wei, Jun S.;
- Jarzembowski, Jason;
- Khan, Javed
Publication type:
Article
Combining Immunocytokine and Ex Vivo Activated NK Cells as a Platform for Enhancing Graft-Versus-Tumor Effects Against GD2<sup>+</sup> Murine Neuroblastoma.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.668307
By:
- Bates, Paul D.;
- Rakhmilevich, Alexander L.;
- Cho, Monica M.;
- Bouchlaka, Myriam N.;
- Rao, Seema L.;
- Hales, Joanna M.;
- Orentas, Rimas J.;
- Fry, Terry J.;
- Gilles, Stephen D.;
- Sondel, Paul M.;
- Capitini, Christian M.
Publication type:
Article
Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.01941
By:
- Jackson, Zachary;
- Roe, Anne;
- Sharma, Ashish Arunkumar;
- Lopes, Filipa Blasco Tavares Pereira;
- Talla, Aarthi;
- Kleinsorge-Block, Sarah;
- Zamborsky, Kayla;
- Schiavone, Jennifer;
- Manjappa, Shivaprasad;
- Schauner, Robert;
- Lee, Grace;
- Liu, Ruifu;
- Caimi, Paolo F.;
- Xiong, Ying;
- Krueger, Winfried;
- Worden, Andrew;
- Kadan, Mike;
- Schneider, Dina;
- Orentas, Rimas;
- Dropulic, Boro
Publication type:
Article
Multispecific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells in a humanized mouse model.
Published in:
Science Translational Medicine, 2019, v. 11, n. 504, p. 1, doi. 10.1126/scitranslmed.aav5685
By:
- Anthony-Gonda, Kim;
- Bardhi, Ariola;
- Ray, Alex;
- Flerin, Nina;
- Li, Mengyan;
- Chen, Weizao;
- Ochsenbauer, Christina;
- Kappes, John C.;
- Krueger, Winfried;
- Worden, Andrew;
- Schneider, Dina;
- Zhu, Zhongyu;
- Orentas, Rimas;
- Dimitrov, Dimiter S.;
- Goldstein, Harris;
- Dropulić, Boro
Publication type:
Article
Autoreactive responses to an environmental factor. 2. Phthalate-induced anti-DNA specificity is downregulated by autoreactive cytotoxic T cells.
Published in:
Immunology, 2004, v. 112, n. 1, p. 94
By:
- Xiaocai Yan;
- Johnson, Bryon D.;
- Orentas, Rimas J.
Publication type:
Article
Immediate transfection of patient-derived leukemia: a novel source for generating cell-based vaccines.
Published in:
Genetic Vaccines & Therapy, 2005, v. 3, p. 4, doi. 10.1186/1479-0556-3-4
By:
- Gershan, Jill A.;
- Johnson, Bryon D.;
- Weber, James;
- Schauer, Dennis W.;
- Natalia, Natalia;
- Behnke, Stephanie;
- Burns, Karen;
- Maloney, Kelly W.;
- Warwick, Anne B.;
- Orentas, Rimas J.
Publication type:
Article
Humoral immune response induced by an engineered cell-based neuroblastoma vaccine with or without CD25 blockade.
Published in:
Acta Biochimica et Biophysica Sinica, 2011, v. 43, n. 2, p. 124, doi. 10.1093/abbs/gmq123
By:
- Zheng, Jin;
- Orentas, Rimas;
- Yan, Xiaofei;
- Liu, Hongli
Publication type:
Article
Discovery of YB-1 as a new immunological target in neuroblastoma by vaccination in the context of regulatory T cell blockade.
Published in:
Acta Biochimica et Biophysica Sinica, 2009, v. 41, n. 12, p. 980, doi. 10.1093/abbs/gmp092
By:
- Zheng, Jin;
- Jing, Weiqing;
- Orentas, Rimas J.
Publication type:
Article
Reference standards for accurate validation and optimization of assays that determine integrated lentiviral vector copy number in transduced cells.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79698-w
By:
- Paugh, Barbara S.;
- Baranyi, Lajos;
- Roy, Andre;
- He, Hua-Jun;
- Harris, Lindsay;
- Cole, Kenneth D.;
- Artlip, Moria;
- Raimund, Caroline;
- Langan, Patricia S.;
- Jana, Srikanta;
- Orentas, Rimas J.;
- Lin-Gibson, Sheng;
- Krueger, Winfried;
- Dropulić, Boro
Publication type:
Article
A Unique Human Immunoglobulin Heavy Chain Variable Domain-Only CD33 CAR for the Treatment of Acute Myeloid Leukemia.
Published in:
Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00539
By:
- Schneider, Dina;
- Xiong, Ying;
- Hu, Peirong;
- Wu, Darong;
- Chen, Weizao;
- Ying, Tianlei;
- Zhu, Zhongyu;
- Dimitrov, Dimiter S.;
- Dropulic, Boro;
- Orentas, Rimas J.
Publication type:
Article
A transplantable TH-MYCN transgenic tumor model in C57Bl/6 mice for preclinical immunological studies in neuroblastoma.
Published in:
International Journal of Cancer, 2014, v. 134, n. 6, p. 1335, doi. 10.1002/ijc.28463
By:
- Kroesen, Michiel;
- Nierkens, Stefan;
- Ansems, Marleen;
- Wassink, Melissa;
- Orentas, Rimas J.;
- Boon, Louis;
- Brok, Martijn H.;
- Hoogerbrugge, Peter M.;
- Adema, Gosse J.
Publication type:
Article
Differential protein-protein interactions underlie signaling mediated by the TCR and a 4-1BB domain–containing CAR.
Published in:
Science Signaling, 2024, v. 17, n. 826, p. 1, doi. 10.1126/scisignal.add4671
By:
- Ritmeester-Loy, Samuel A.;
- Draper, Isabella H.;
- Bueter, Eric C.;
- Lautz, Jonathan D.;
- Zhang-Wong, Yue;
- Gustafson, Joshua A.;
- Wilson, Ashley L.;
- Lin, Chenwei;
- Gafken, Philip R.;
- Jensen, Michael C.;
- Orentas, Rimas;
- Smith, Stephen E. P.
Publication type:
Article
TSCM/TCM-ENRICHED ANTI-HIV duoCAR-T CELLS EXERT POTENT HIV CONTROL.
Published in:
Topics in Antiviral Medicine, 2023, v. 31, n. 2, p. 158
By:
- Anthony-Gonda, Kim;
- Ray, Alex;
- Su, Hang;
- Chilunda, Vanessa;
- Lee, Danica;
- Weiselberg, Jessica;
- Zemelko, Lily;
- Yen Wang;
- Reese, Jane;
- Orentas, Rimas;
- Deeks, Steven G.;
- Rutishauser, Rachel L.;
- Berman, Joan W.;
- Goldstein, Harris;
- Dropulic, Boro
Publication type:
Article
Murine rhabdomyosarcoma is immunogenic and responsive to T-cell-based immunotherapy.
Published in:
Pediatric Blood & Cancer, 2011, v. 57, n. 6, p. 921, doi. 10.1002/pbc.23048
By:
- Meadors, Joanna L.;
- Cui, Yonghzi;
- Chen, Qing-Rong;
- Song, Young K.;
- Khan, Javed;
- Merlino, Glenn;
- Tsokos, Maria;
- Orentas, Rimas J.;
- Mackall, Crystal L.
Publication type:
Article
Nothing about us without us: Advocacy and engagement in genetic medicine.
Published in:
Science Translational Medicine, 2024, v. 16, n. 746, p. 1, doi. 10.1126/scitranslmed.adn2401
By:
- Olayiwola, Olabimpe;
- Castillejo, Adam;
- Louella, Michael;
- Supercharger, Moses;
- Harlow, Evelyn;
- Dee, Lynda;
- Abdallah, Khadidja;
- Kityo-Mutuluuza, Cissy;
- Adair, Jennifer E.;
- Orentas, Rimas;
- Dubé, Karine
Publication type:
Article
Trispecific CD19-CD20-CD22–targeting duoCAR-T cells eliminate antigen-heterogeneous B cell tumors in preclinical models.
Published in:
Science Translational Medicine, 2021, v. 13, n. 586, p. 1, doi. 10.1126/scitranslmed.abc6401
By:
- Schneider, Dina;
- Xiong, Ying;
- Wu, Darong;
- Hu, Peirong;
- Alabanza, Leah;
- Steimle, Brittany;
- Mahmud, Hasan;
- Anthony-Gonda, Kim;
- Krueger, Winfried;
- Zhu, Zhongyu;
- Dimitrov, Dimiter S.;
- Orentas, Rimas J.;
- Dropulić, Boro
Publication type:
Article
Tumor antigen analysis in neuroblastoma by serological interrogation of bioinformatic data.
Published in:
Cancer Science, 2010, v. 101, n. 11, p. 2316, doi. 10.1111/j.1349-7006.2010.01694.x
By:
- Kohler, M. Eric;
- Johnson, Bryon D.;
- Palen, Katie;
- Chen, Qing-Rong;
- Khan, Javed;
- Orentas, Rimas J.
Publication type:
Article

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