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A Semi-Synthetic Glycoconjugate Vaccine Candidate for Carbapenem-Resistant Klebsiella pneumoniae.
Published in:
Angewandte Chemie, 2017, v. 129, n. 45, p. 14161, doi. 10.1002/ange.201700964
By:
- Seeberger, Peter H.;
- Pereira, Claney L.;
- Khan, Naeem;
- Xiao, Guozhi;
- Diago‐Navarro, Elizabeth;
- Reppe, Katrin;
- Opitz, Bastian;
- Fries, Bettina C.;
- Witzenrath, Martin
Publication type:
Article
Recognition of Streptococcus pneumoniae by the innate immune system.
Published in:
Cellular Microbiology, 2012, v. 14, n. 4, p. 460, doi. 10.1111/j.1462-5822.2011.01746.x
By:
- Koppe, Uwe;
- Suttorp, Norbert;
- Opitz, Bastian
Publication type:
Article
Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice.
Published in:
Cellular Microbiology, 2011, v. 13, n. 11, p. 1668, doi. 10.1111/j.1462-5822.2011.01646.x
By:
- Lippmann, Juliane;
- Müller, Holger C.;
- Naujoks, Jan;
- Tabeling, Christoph;
- Shin, Sunny;
- Witzenrath, Martin;
- Hellwig, Katharina;
- Kirschning, Carsten J.;
- Taylor, Gregory A.;
- Barchet, Winfried;
- Bauer, Stefan;
- Suttorp, Norbert;
- Roy, Craig R.;
- Opitz, Bastian
Publication type:
Article
IFNβ responses induced by intracellular bacteria or cytosolic DNA in different human cells do not require ZBP1 (DLM-1/DAI).
Published in:
Cellular Microbiology, 2008, v. 10, n. 12, p. 2579, doi. 10.1111/j.1462-5822.2008.01232.x
By:
- Lippmann, Juliane;
- Rothenburg, Stefan;
- Deigendesch, Nikolaus;
- Eitel, Julia;
- Meixenberger, Karolin;
- van Laak, Vincent;
- Slevogt, Hortense;
- Dje N'Guessan, Philippe;
- Hippenstiel, Stefan;
- Chakraborty, Trinad;
- Flieger, Antje;
- Suttorp, Norbert;
- Opitz, Bastian
Publication type:
Article
IFNβ induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein.
Published in:
Cellular Microbiology, 2007, v. 9, n. 4, p. 930, doi. 10.1111/j.1462-5822.2006.00841.x
By:
- Opitz, Bastian;
- Rejaibi, Amira;
- Dauber, Bianca;
- Eckhard, Jamina;
- Vinzing, Maya;
- Schmeck, Bernd;
- Hippenstiel, Stefan;
- Suttorp, Norbert;
- Wolff, Thorsten
Publication type:
Article
Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger-like mechanism and initiates a TLR2- and partly NOD1-dependent inflammatory immune response.
Published in:
Cellular Microbiology, 2007, v. 9, n. 3, p. 694, doi. 10.1111/j.1462-5822.2006.00821.x
By:
- Slevogt, Hortense;
- Seybold, Joachim;
- Tiwari, Krishna N.;
- Hocke, Andreas C.;
- Jonatat, Carola;
- Dietel, Solveig;
- Hippenstiel, Stefan;
- Singer, Bernhard B.;
- Bachmann, Sebastian;
- Suttorp, Norbert;
- Opitz, Bastian
Publication type:
Article
STING SNP R293Q Is Associated with a Decreased Risk of Aging-Related Diseases.
Published in:
2019
By:
- Hamann, Lutz;
- Ruiz-Moreno, Juan S.;
- Szwed, Malgorzata;
- Mossakowska, Malgorzata;
- Lundvall, Linn;
- Schumann, Ralf R.;
- Opitz, Bastian;
- Puzianowska-Kuznicka, Monika;
- Ruiz-Moreno, Juan S;
- Schumann, Ralf R
Publication type:
journal article
A Semi-Synthetic Glycoconjugate Vaccine Candidate for Carbapenem-Resistant Klebsiella pneumoniae.
Published in:
Angewandte Chemie International Edition, 2017, v. 56, n. 45, p. 13973, doi. 10.1002/anie.201700964
By:
- Seeberger, Peter H.;
- Pereira, Claney L.;
- Khan, Naeem;
- Xiao, Guozhi;
- Diago‐Navarro, Elizabeth;
- Reppe, Katrin;
- Opitz, Bastian;
- Fries, Bettina C.;
- Witzenrath, Martin
Publication type:
Article
CLEC12A Binds to Legionella pneumophila but Has No Impact on the Host's Antibacterial Response.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3891, doi. 10.3390/ijms24043891
By:
- Klatt, Ann-Brit;
- Diersing, Christina;
- Lippmann, Juliane;
- Mayer-Lambertz, Sabine;
- Stegmann, Felix;
- Fischer, Swantje;
- Caesar, Sandra;
- Fiocca Vernengo, Facundo;
- Hönzke, Katja;
- Hocke, Andreas C.;
- Ruland, Jürgen;
- Witzenrath, Martin;
- Lepenies, Bernd;
- Opitz, Bastian
Publication type:
Article
Pseudomonas aeruginosa Triggered Exosomal Release of ADAM10 Mediates Proteolytic Cleavage in Trans.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1259, doi. 10.3390/ijms23031259
By:
- Aljohmani, Ahmad;
- Opitz, Bastian;
- Bischoff, Markus;
- Yildiz, Daniela
Publication type:
Article
Endothelin B Receptor Immunodynamics in Pulmonary Arterial Hypertension.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.895501
By:
- Tabeling, Christoph;
- González Calera, Carla R.;
- Lienau, Jasmin;
- Höppner, Jakob;
- Tschernig, Thomas;
- Kershaw, Olivia;
- Gutbier, Birgitt;
- Naujoks, Jan;
- Herbert, Julia;
- Opitz, Bastian;
- Gruber, Achim D.;
- Hocher, Berthold;
- Suttorp, Norbert;
- Heidecke, Harald;
- Burmester, Gerd-R.;
- Riemekasten, Gabriela;
- Siegert, Elise;
- Kuebler, Wolfgang M.;
- Witzenrath, Martin
Publication type:
Article
Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27478-z
By:
- Wee, Bryan A.;
- Alves, Joana;
- Lindsay, Diane S. J.;
- Klatt, Ann-Brit;
- Sargison, Fiona A.;
- Cameron, Ross L.;
- Pickering, Amy;
- Gorzynski, Jamie;
- Corander, Jukka;
- Marttinen, Pekka;
- Opitz, Bastian;
- Smith, Andrew J.;
- Fitzgerald, J. Ross
Publication type:
Article
Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study.
Published in:
Infection, 2022, v. 50, n. 6, p. 1441, doi. 10.1007/s15010-022-01796-w
By:
- Lingscheid, Tilman;
- Lippert, Lena J.;
- Hillus, David;
- Kruis, Tassilo;
- Thibeault, Charlotte;
- Helbig, Elisa T.;
- Tober-Lau, Pinkus;
- Pfäfflin, Frieder;
- Müller-Redetzky, Holger;
- Witzenrath, Martin;
- Zoller, Thomas;
- Uhrig, Alexander;
- Opitz, Bastian;
- Suttorp, Norbert;
- Kramer, Tobias S.;
- Sander, Leif E.;
- Stegemann, Miriam S.;
- Kurth, Florian
Publication type:
Article
Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19).
Published in:
Infection, 2020, v. 48, n. 4, p. 619, doi. 10.1007/s15010-020-01464-x
By:
- Kurth, Florian;
- Roennefarth, Maria;
- Thibeault, Charlotte;
- Corman, Victor M.;
- Müller-Redetzky, Holger;
- Mittermaier, Mirja;
- Ruwwe-Glösenkamp, Christoph;
- Heim, Katrin M.;
- Krannich, Alexander;
- Zvorc, Saskia;
- Schmidt, Sein;
- Kretzler, Lucie;
- Dang-Heine, Chantip;
- Rose, Matthias;
- Hummel, Michael;
- Hocke, Andreas;
- Hübner, Ralf H.;
- Opitz, Bastian;
- Mall, Marcus A.;
- Röhmel, Jobst
Publication type:
Article
NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence.
Published in:
Scientific Reports, 2016, p. 30943, doi. 10.1038/srep30943
By:
- Kostadinova, Elena;
- Chaput, Catherine;
- Gutbier, Birgitt;
- Lippmann, Juliane;
- Sander, Leif E.;
- Mitchell, Timothy J.;
- Suttorp, Norbert;
- Witzenrath, Martin;
- Opitz, Bastian
Publication type:
Article
Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue.
Published in:
PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0137108
By:
- Fatykhova, Diana;
- Rabes, Anne;
- Machnik, Christoph;
- Guruprasad, Kunchur;
- Pache, Florence;
- Berg, Johanna;
- Toennies, Mario;
- Bauer, Torsten T.;
- Schneider, Paul;
- Schimek, Maria;
- Eggeling, Stephan;
- Mitchell, Timothy J.;
- Mitchell, Andrea M.;
- Hilker, Rolf;
- Hain, Torsten;
- Suttorp, Norbert;
- Hippenstiel, Stefan;
- Hocke, Andreas C.;
- Opitz, Bastian
Publication type:
Article
The C-Type Lectin Receptor Mincle Binds to Streptococcus pneumoniae but Plays a Limited Role in the Anti-Pneumococcal Innate Immune Response.
Published in:
PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0117022
By:
- Rabes, Anne;
- Zimmermann, Stephanie;
- Reppe, Katrin;
- Lang, Roland;
- Seeberger, Peter H.;
- Suttorp, Norbert;
- Witzenrath, Martin;
- Lepenies, Bernd;
- Opitz, Bastian
Publication type:
Article
Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila pneumoniae Infected Human Mononuclear Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030379
By:
- Eitel, Julia;
- Meixenberger, Karolin;
- van Laak, Claudia;
- Orlovski, Christine;
- Hocke, Andreas;
- Schmeck, Bernd;
- Hippenstiel, Stefan;
- Dje N'Guessan, Philippe;
- Suttorp, Norbert;
- Opitz, Bastian
Publication type:
Article
The UspA1 Protein of Moraxella catarrhalis Induces CEACAM-1--Dependent Apoptosis in Alveolar Epithelial Cells.
Published in:
Journal of Infectious Diseases, 2007, v. 195, n. 11, p. 1651, doi. 10.1086/514820
By:
- NGuessan, Philippe Dje;
- Vigelahn, Manuel;
- Bachmann, Sebastian;
- Zabel, Solveig;
- Opitz, Bastian;
- Schmeck, Bernd;
- Hippenstiel, Stefan;
- Zweigner, Janine;
- Riesbeck, Kristian;
- Singer, Bernhard B.;
- Suttorp, Norbert;
- Slevogt, Hortense
Publication type:
Article
Platelets Restrict the Oxidative Burst in Phagocytes and Facilitate Primary Progressive Tuberculosis.
Published in:
2020
By:
- Scheuermann, Lisa;
- Gang Pei;
- Domaszewska, Teresa;
- Zyla, Joanna;
- Oberbeck-Müller, Dagmar;
- Bandermann, Silke;
- Yonghong Feng;
- Ruiz Moreno, Juan Sebastian;
- Opitz, Bastian;
- Mollenkopf, Hans-Joachim;
- Kaufmann, Stefan H. E.;
- Dorhoi, Anca;
- Pei, Gang;
- Feng, Yonghong;
- Kaufmann, Stefan He
Publication type:
journal article
Inflammasome Deficiency Makes Pro-resolving Lipid Mediators Great Again.
Published in:
2017
By:
- Opitz, Bastian
Publication type:
journal article
Legionella pneumophila induces human betaDefensin-3 in pulmonary cells.
Published in:
Respiratory Research, 2010, v. 11, p. 93, doi. 10.1186/1465-9921-11-93
By:
- Scharf, Stefanie;
- Vardarova, Kremena;
- Lang, Friederike;
- Schmeck, Bernd;
- Opitz, Bastian;
- Flieger, Antje;
- Heuner, Klaus;
- Hippenstiel, Stefan;
- Suttorp, Norbert;
- N'Guessan, Philippe D.
Publication type:
Article
Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells.
Published in:
Respiratory Research, 2006, v. 7, p. 1, doi. 10.1186/1465-9921-7-98
By:
- Schmeck, Bernd;
- Moog, Kerstin;
- Zahlten, Janine;
- Van Laak, Vincent;
- N'Guessan, Philippe Dje;
- Opitz, Bastian;
- Rosseau, Simone;
- Suttorp, Norbert;
- Hippenstiel, Stefan
Publication type:
Article
Lung epithelium as a sentinel and effector system in pneumonia -- molecular mechanisms of pathogen recognition and signal transduction.
Published in:
Respiratory Research, 2006, v. 7, p. 97, doi. 10.1186/1465-9921-7-97
By:
- Hippenstiel, Stefan;
- Opitz, Bastian;
- Schmeck, Bernd;
- Suttorp, Norbert
Publication type:
Article
Selective catalytic reduction: Adding an ammonia slip catalyst mitigates dosing errors.
Published in:
Canadian Journal of Chemical Engineering, 2022, v. 100, n. 6, p. 1439, doi. 10.1002/cjce.24293
By:
- Bendrich, Michelle;
- Opitz, Bastian;
- Scheuer, Alexander;
- Hayes, Robert E.;
- Votsmeier, Martin
Publication type:
Article
Increasing the inspiratory time and I:E ratio during mechanical ventilation aggravates ventilator-induced lung injury in mice.
Published in:
Critical Care, 2015, v. 19, n. 1, p. 1, doi. 10.1186/s13054-015-0759-2
By:
- Müller-Redetzky, Holger C.;
- Felten, Matthias;
- Hellwig, Katharina;
- Wienhold, Sandra-Maria;
- Naujoks, Jan;
- Opitz, Bastian;
- Kershaw, Olivia;
- Gruber, Achim D.;
- Suttorp, Norbert;
- Witzenrath, Martin
Publication type:
Article
TBK1's Role in Bacterial Pneumonia: Perhaps More than Macrophages and IFNs.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 6, p. 596, doi. 10.1165/rcmb.2022-0040ED
By:
- Fiocca Vernengo, Facundo;
- Opitz, Bastian
Publication type:
Article
Microbiota-Dependent Regulation of Antimicrobial Immunity in the Lung.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2019, v. 61, n. 3, p. 284, doi. 10.1165/rcmb.2019-0101TR
By:
- Maschirow, Laura;
- Suttorp, Norbert;
- Opitz, Bastian
Publication type:
Article
Nucleotide Oligomerization Domain 1 Ligation Suppressed Murine Allergen-Specific T-Cell Proliferation and Airway Hyperresponsiveness.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2014, v. 50, n. 5, p. 903, doi. 10.1165/rcmb.2013-0333oc
By:
- Tabeling, Christoph;
- Scheer, Heide;
- Schönrock, Stefanie M.;
- Runge, Franziska;
- Gutbier, Birgitt;
- Lienau, Jasmin;
- Hamelmann, Eckard;
- Opitz, Bastian;
- Suttorp, Norbert;
- Mayer, Konstantin;
- Behrens, Georg M.;
- Tschernig, Thomas;
- Witzenrath, Martin
Publication type:
Article
CEACAM1 inhibits Toll-like receptor 2–triggered antibacterial responses of human pulmonary epithelial cells.
Published in:
Nature Immunology, 2008, v. 9, n. 11, p. 1270, doi. 10.1038/ni.1661
By:
- Slevogt, Hortense;
- Zabel, Solveig;
- Opitz, Bastian;
- Hocke, Andreas;
- Eitel, Julia;
- N'Guessan, Philippe D;
- Lucka, Lothar;
- Riesbeck, Kristian;
- Zimmermann, Wolfgang;
- Zweigner, Janine;
- Temmesfeld-Wollbrueck, Bettina;
- Suttorp, Norbert;
- Singer, Bernhard B
Publication type:
Article
PKCα Deficiency in Mice Is Associated with Pulmonary Vascular Hyperresponsiveness to Thromboxane A2 and Increased Thromboxane Receptor Expression.
Published in:
Journal of Vascular Research, 2016, v. 52, n. 4, p. 279, doi. 10.1159/000443402
By:
- Tabeling, Christoph;
- Noe, Elena;
- Naujoks, Jan;
- Doehn, Jan-Moritz;
- Hippenstiel, Stefan;
- Opitz, Bastian;
- Suttorp, Norbert;
- Klopfleisch, Robert;
- Witzenrath, Martin
Publication type:
Article
The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires’ disease in humans.
Published in:
PLoS Pathogens, 2018, v. 14, n. 1, p. 1, doi. 10.1371/journal.ppat.1006829
By:
- Ruiz-Moreno, Juan S.;
- Hamann, Lutz;
- Shah, Javeed A.;
- Verbon, Annelies;
- Mockenhaupt, Frank P.;
- Puzianowska-Kuznicka, Monika;
- Naujoks, Jan;
- Sander, Leif E.;
- Witzenrath, Martin;
- Cambier, John C.;
- Suttorp, Norbert;
- Schumann, Ralf R.;
- Jin, Lei;
- Hawn, Thomas R.;
- Opitz, Bastian;
- null, null
Publication type:
Article
Adhesion of Moraxella catarrhalis to human bronchial epithelium characterized by a novel fluorescence-based assay.
Published in:
Medical Microbiology & Immunology, 2006, v. 195, n. 2, p. 73, doi. 10.1007/s00430-005-0003-9
By:
- Slevogt, Hortense;
- Tiwari, Krishna N.;
- Schmeck, Bernd;
- Hocke, Andreas;
- Opitz, Bastian;
- Suttorp, Norbert;
- Seybold, Joachim
Publication type:
Article
The microbiota in pneumonia: From protection to predisposition.
Published in:
Science Translational Medicine, 2021, v. 13, n. 576, p. 1, doi. 10.1126/scitranslmed.aba0501
By:
- Thibeault, Charlotte;
- Suttorp, Norbert;
- Opitz, Bastian
Publication type:
Article
NOD-like receptors in lung diseases.
Published in:
Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00393
By:
- Chaput, Catherine;
- Sander, Leif Erik;
- Suttorp, Norbert;
- Opitz, Bastian
Publication type:
Article
Spectrum of pathogen-and model-specific histopathologies in mouse models of acute pneumonia.
Published in:
PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0188251
By:
- Dietert, Kristina;
- Gutbier, Birgitt;
- Wienhold, Sandra M.;
- Reppe, Katrin;
- Xiaohui Jiang;
- Ling Yao;
- Chaput, Catherine;
- Naujoks, Jan;
- Brack, Markus;
- Kupke, Alexandra;
- Peteranderl, Christin;
- Becker, Stephan;
- von Lachner, Carolin;
- Baal, Nelli;
- Slevogt, Hortense;
- Hocke, Andreas C.;
- Witzenrath, Martin;
- Opitz, Bastian;
- Herold, Susanne;
- Hackstein, Holger
Publication type:
Article
Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice.
Published in:
2018
By:
- Wienhold, Sandra-Maria;
- Macrì, Mario;
- Nouailles, Geraldine;
- Dietert, Kristina;
- Gurtner, Corinne;
- Gruber, Achim D.;
- Heimesaat, Markus M.;
- Lienau, Jasmin;
- Schumacher, Fabian;
- Kleuser, Burkhard;
- Opitz, Bastian;
- Suttorp, Norbert;
- Witzenrath, Martin;
- Müller-Redetzky, Holger C.
Publication type:
journal article

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