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Metformin Induces a Dietary Restriction-Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1.
Published in:
PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008758
By:
- Onken, Brian;
- Driscoll, Monica
Publication type:
Article
Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension.
Published in:
PLoS Genetics, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.pgen.1008982
By:
- Onken, Brian;
- Kalinava, Natallia;
- Driscoll, Monica
Publication type:
Article
Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes.
Published in:
GeroScience, 2024, v. 46, n. 2, p. 2239, doi. 10.1007/s11357-023-00978-0
By:
- Banse, Stephen A.;
- Sedore, Christine A.;
- Johnson, Erik;
- Coleman-Hulbert, Anna L.;
- Onken, Brian;
- Hall, David;
- Jackson, E. Grace;
- Huynh, Phu;
- Foulger, Anna C.;
- Guo, Suzhen;
- Garrett, Theo;
- Xue, Jian;
- Inman, Delaney;
- Morshead, Mackenzie L.;
- Plummer, W. Todd;
- Chen, Esteban;
- Bhaumik, Dipa;
- Chen, Michelle K.;
- Harinath, Girish;
- Chamoli, Manish
Publication type:
Article
Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions.
Published in:
GeroScience, 2019, v. 41, n. 6, p. 945, doi. 10.1007/s11357-019-00108-9
By:
- Banse, Stephen A.;
- Lucanic, Mark;
- Sedore, Christine A.;
- Coleman-Hulbert, Anna L.;
- Plummer, W. Todd;
- Chen, Esteban;
- Kish, Jason L.;
- Hall, David;
- Onken, Brian;
- Presley, Michael P.;
- Jones, E. Grace;
- Blue, Benjamin W.;
- Garrett, Theo;
- Abbott, Mark;
- Xue, Jian;
- Guo, Suzhen;
- Johnson, Erik;
- Foulger, Anna C.;
- Chamoli, Manish;
- Falkowski, Ron
Publication type:
Article
Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects.
Published in:
Nature Communications, 2017, v. 8, n. 2, p. 14256, doi. 10.1038/ncomms14256
By:
- Lucanic, Mark;
- Plummer, W. Todd;
- Chen, Esteban;
- Harke, Jailynn;
- Foulger, Anna C.;
- Onken, Brian;
- Coleman-Hulbert, Anna L.;
- Dumas, Kathleen J.;
- Guo, Suzhen;
- Johnson, Erik;
- Bhaumik, Dipa;
- Xue, Jian;
- Crist, Anna B.;
- Presley, Michael P.;
- Harinath, Girish;
- Sedore, Christine A.;
- Chamoli, Manish;
- Kamat, Shaunak;
- Chen, Michelle K.;
- Angeli, Suzanne
Publication type:
Article
Deletion of microRNA-80 Activates Dietary Restriction to Extend <i>C. elegans</i> Healthspan and Lifespan.
Published in:
PLoS Genetics, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pgen.1003737
By:
- Vora, Mehul;
- Shah, Mitalie;
- Ostafi, Silvana;
- Onken, Brian;
- Xue, Jian;
- Ni, Julie Zhouli;
- Gu, Sam;
- Driscoll, Monica
Publication type:
Article
A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans.
Published in:
PLoS Genetics, 2008, v. 4, n. 2, p. 1, doi. 10.1371/journal.pgen.0040024
By:
- Hansen, Malene;
- Chandra, Abha;
- Mitic, Laura L.;
- Onken, Brian;
- Driscoll, Monica;
- Kenyon, Cynthia
Publication type:
Article
Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes.
Published in:
Aging Cell, 2022, v. 21, n. 1, p. 1, doi. 10.1111/acel.13488
By:
- Onken, Brian;
- Sedore, Christine A.;
- Coleman‐Hulbert, Anna L.;
- Hall, David;
- Johnson, Erik;
- Jones, Eleanor Grace;
- Banse, Stephen A.;
- Huynh, Phu;
- Guo, Suzhen;
- Xue, Jian;
- Chen, Esteban;
- Harinath, Girish;
- Foulger, Anna C.;
- Chao, Elizabeth A.;
- Hope, June;
- Bhaumik, Dipa;
- Plummer, Todd;
- Inman, Delaney;
- Morshead, Mackenzie;
- Guo, Max
Publication type:
Article

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