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MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles.
- Published in:
- Nature Reviews Drug Discovery, 2012, v. 11, n. 11, p. 860, doi. 10.1038/nrd3864
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- Publication type:
- Article
Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34255-z
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- Publication type:
- Article
MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver.
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- EMBO Molecular Medicine, 2014, v. 6, n. 12, p. 1610, doi. 10.15252/emmm.201404218
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- Publication type:
- Article
The heart-liver metabolic axis: defective communication exacerbates disease.
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- EMBO Molecular Medicine, 2014, v. 6, n. 4, p. 436, doi. 10.1002/emmm.201303800
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- Publication type:
- Article
HDAC4 inhibits cell-cycle progression and protects neurons from cell death.
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- Developmental Neurobiology (19328451), 2008, v. 68, n. 8, p. 1076, doi. 10.1002/dneu.20637
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- Article
Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor.
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- Nature Medicine, 2002, v. 8, n. 11, p. 1303, doi. 10.1038/nm789
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- Publication type:
- Article
Decoding calcium signals involved in cardiac growth and function.
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- Nature Medicine, 2000, v. 6, n. 11, p. 1221, doi. 10.1038/81321
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- Publication type:
- Article
Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway.
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- EMBO Journal, 2001, v. 20, n. 22, p. 6414, doi. 10.1093/emboj/20.22.6414
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- Article
Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy.
- Published in:
- EMBO Journal, 2001, v. 20, n. 11, p. 2757, doi. 10.1093/emboj/20.11.2757
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- Publication type:
- Article
MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type.
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- EMBO Journal, 2000, v. 19, n. 9, p. 1963, doi. 10.1093/emboj/19.9.1963
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- Publication type:
- Article
D-mef2 is a target for Tinman activation during Drosophila heart development.
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- EMBO Journal, 1997, v. 16, n. 3, p. 515, doi. 10.1093/emboj/16.3.515
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- Publication type:
- Article
KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.
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- Journal of Clinical Investigation, 2014, v. 124, n. 8, p. 3529, doi. 10.1172/JCI74994
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- Article
Macrophages are required for neonatal heart regeneration.
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- Journal of Clinical Investigation, 2014, v. 124, n. 3, p. 1382, doi. 10.1172/JCI72181
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- Publication type:
- Article
Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism.
- Published in:
- 2013
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- Publication type:
- journal article
Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae.
- Published in:
- 2013
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- Publication type:
- journal article
Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae.
- Published in:
- Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 2193, doi. 10.1172/JCI64201
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- Publication type:
- Article
MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment.
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- Journal of Clinical Investigation, 2013, v. 123, n. 1, p. 11, doi. 10.1172/JCI62876
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- Publication type:
- Article
microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice.
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- Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2054, doi. 10.1172/JCI62656
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- Publication type:
- Article
MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca<sup>2+</sup> overload and cell death.
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- Journal of Clinical Investigation, 2012, v. 122, n. 4, p. 1222, doi. 10.1172/JCI59327
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- Article
Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy.
- Published in:
- 2011
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- journal article
Response to Thum et al.
- Published in:
- 2011
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- Publication type:
- Letter
Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice.
- Published in:
- 2010
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- Publication type:
- journal article
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.
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- 2009
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- Publication type:
- journal article
Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation.
- Published in:
- Journal of Clinical Investigation, 2008, v. 118, n. 11, p. 3598, doi. 10.1172/JCI36277
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- Publication type:
- Article
Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice.
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- Journal of Clinical Investigation, 2008, v. 118, n. 11, p. 3588, doi. 10.1172/JCI35847
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- Publication type:
- Article
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice.
- Published in:
- 2008
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- Publication type:
- journal article
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice.
- Published in:
- Journal of Clinical Investigation, 2008, v. 118, n. 1, p. 124, doi. 10.1172/JCI33255
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- Publication type:
- Article
Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3.
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- 2007
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- Publication type:
- journal article
Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.
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- 2007
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- Publication type:
- journal article
MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets.
- Published in:
- Journal of Clinical Investigation, 2007, v. 117, n. 9, p. 2369, doi. 10.1172/JCI33099
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- Publication type:
- Article
Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity.
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- Journal of Clinical Investigation, 2007, v. 117, n. 5, p. 1324, doi. 10.1172/JCI31240
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- Publication type:
- Article
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling.
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- 2006
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- Publication type:
- journal article
CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy.
- Published in:
- Journal of Clinical Investigation, 2006, v. 116, n. 7, p. 1853, doi. 10.1172/JCI27438
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- Publication type:
- Article
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling.
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- 2006
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- Publication type:
- journal article
Local InsP<sub>3</sub>-dependent perinuclear Ca<sup>2+</sup> signaling in cardiac myocyte excitation-transcription coupling.
- Published in:
- Journal of Clinical Investigation, 2006, v. 116, n. 3, p. 675, doi. 10.1172/JCI27374
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- Publication type:
- Article
Toward transcriptional therapies for the failing heart: chemical screens to modulate genes.
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- Journal of Clinical Investigation, 2005, v. 115, n. 3, p. 538, doi. 10.1172/JCI200524144
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- Publication type:
- Article
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore.
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- 2004
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- Publication type:
- journal article
A New Subclass of Helix-Loop-Helix Transcription Factors Expressed in Paraxial Mesoderm and Chondrogenic Cell Lineages.
- Published in:
- Annals of the New York Academy of Sciences, 1996, v. 785, n. 1, p. 108, doi. 10.1111/j.1749-6632.1996.tb56248.x
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- Publication type:
- Article
Activated calcineurin ameliorates contraction-induced injury to skeletal muscles of mdx dystrophic mice.
- Published in:
- Journal of Physiology, 2006, v. 575, n. 2, p. 645, doi. 10.1113/jphysiol.2006.108472
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- Publication type:
- Article
KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.26439.001
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- Publication type:
- Article
Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25653-w
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- Article
Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.
- Published in:
- Science Signaling, 2016, v. 9, n. 457, p. 1, doi. 10.1126/scisignal.aaj1460
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- Publication type:
- Article
MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1.
- Published in:
- Nature Medicine, 2014, v. 20, n. 4, p. 368, doi. 10.1038/nm.3487
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- Article
Heart repair by cardiac reprogramming.
- Published in:
- Nature Medicine, 2013, v. 19, n. 4, p. 413, doi. 10.1038/nm.3147
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- Publication type:
- Article
Deacetylase inhibition promotes the generation and function of regulatory T cells.
- Published in:
- Nature Medicine, 2007, v. 13, n. 11, p. 1299, doi. 10.1038/nm1652
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- Publication type:
- Article
Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress.
- Published in:
- Nature Medicine, 2004, v. 10, n. 12, p. 1336, doi. 10.1038/nm1132
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- Article
A decade of discoveries in cardiac biology.
- Published in:
- Nature Medicine, 2004, v. 10, n. 5, p. 467, doi. 10.1038/nm0504-467
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- Publication type:
- Article
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis.
- Published in:
- Nature Genetics, 2002, v. 31, n. 1, p. 25, doi. 10.1038/ng866
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- Publication type:
- Article
Thymosin β4 and cardiac repair.
- Published in:
- Annals of the New York Academy of Sciences, 2010, v. 1194, n. 1, p. 87, doi. 10.1111/j.1749-6632.2010.05468.x
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- Publication type:
- Article
Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer.
- Published in:
- Genesis: The Journal of Genetics & Development, 2002, v. 33, n. 2, p. 77, doi. 10.1002/gene.10092
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- Publication type:
- Article