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Unexpected Isomerisation of a Fragment Analogue During Fragment-Based Screening of HIV Integrase Catalytic Core Domain.
Published in:
Australian Journal of Chemistry, 2015, v. 68, n. 12, p. 1871, doi. 10.1071/CH15587
By:
- Ryan, John H.;
- Jarvis, Karen E.;
- Mulder, Roger J.;
- Francis, Craig L.;
- Savage, G. Paul;
- Dolezal, Olan;
- Peat, Thomas S.;
- Deadman, John J.
Publication type:
Article
Fragment Screening for the Modelling Community: SPR, ITC, and Crystallography.
Published in:
Australian Journal of Chemistry, 2013, v. 66, n. 12, p. 1507, doi. 10.1071/CH13302
By:
- Dolezal, Olan;
- Doughty, Larissa;
- Hattarki, Meghan K.;
- Fazio, Vincent J.;
- Caradoc-Davies, Tom T.;
- Newman, Janet;
- Peat, Thomas S.
Publication type:
Article
Construction of the CSIRO Fragment Library.
Published in:
Australian Journal of Chemistry, 2013, v. 66, n. 12, p. 1473, doi. 10.1071/CH13325
By:
- Francis, Craig L.;
- Kenny, Peter W.;
- Dolezal, Olan;
- Saubern, Simon;
- Kruger, Megan;
- Savage, G. Paul;
- Peat, Thomas S.;
- Ryan, John H.
Publication type:
Article
Fragment Screening on Staphylococcus aureus HPPK - a Folate Pathway Target.
Published in:
Australian Journal of Chemistry, 2013, v. 66, n. 12, p. 1537, doi. 10.1071/CH13298
By:
- Chhabra, Sandeep;
- Dolezal, Olan;
- Hattarki, Meghan;
- Peat, Thomas S.;
- Simpson, Jamie S.;
- Swarbrick, James D.
Publication type:
Article
Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening.
Published in:
Australian Journal of Chemistry, 2013, v. 66, n. 12, p. 1530, doi. 10.1071/CH13266
By:
- Lim, San Sui;
- Debono, Cael O.;
- MacRaild, Christopher A.;
- Chandrashekaran, Indu R.;
- Dolezal, Olan;
- Anders, Robin F.;
- Simpson, Jamie S.;
- Scanlon, Martin J.;
- Devine, Shane M.;
- Scammells, Peter J.;
- Norton, Raymond S.
Publication type:
Article
Analysis of Bovine Lactoferrin in Infant Formula and Adult Nutritional Products by Optical Biosensor Immunoassay: Collaborative Study, Final Action 2021.07.
Published in:
Journal of AOAC International, 2024, v. 107, n. 5, p. 833, doi. 10.1093/jaoacint/qsae042
By:
- Gill, Brendon D;
- Indyk, Harvey E;
- Kobayashi, Tadashi;
- Wood, Jackie E;
- Clow, Fiona;
- Dolezal, Olan;
- Hartley-Tassell, Lauren;
- Jones, Martina;
- Kelton, William;
- Stoller, Robyn;
- Wilkinson-White, Lorna
Publication type:
Article
Exploring the Chemical Space around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme HPPK.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0059535
By:
- Chhabra, Sandeep;
- Barlow, Nicholas;
- Dolezal, Olan;
- Hattarki, Meghan K.;
- Newman, Janet;
- Peat, Thomas S.;
- Graham, Bim;
- Swarbrick, James D.
Publication type:
Article
Structural Model for the Interaction of a Designed Ankyrin Repeat Protein with the Human Epidermal Growth Factor Receptor 2.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059163
By:
- Epa, V. Chandana;
- Dolezal, Olan;
- Doughty, Larissa;
- Xiao, Xiaowen;
- Jost, Christian;
- Plückthun, Andreas;
- Adams, Timothy E.
Publication type:
Article
Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040147
By:
- Peat, Thomas S.;
- Rhodes, David I.;
- Vandegraaff, Nick;
- Giang Le;
- Smith, Jessica A.;
- Clark, Lisa J.;
- Jones, Eric D.;
- Coates, Jonathan A. V.;
- Thienthong, Neeranat;
- Newman, Janet;
- Dolezal, Olan;
- Mulder, Roger;
- Ryan, John H.;
- Paul Savage, G.;
- Francis, Craig L.;
- Deadman, John J.
Publication type:
Article
Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029444
By:
- Chhabra, Sandeep;
- Dolezal, Olan;
- Collins, Brett M.;
- Newman, Janet;
- Simpson, Jamie S.;
- Macreadie, Ian G.;
- Fernley, Ross;
- Peat, Thomas S.;
- Swarbrick, James D.
Publication type:
Article
Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide.
Published in:
Proteins, 2013, v. 81, n. 10, p. 1748, doi. 10.1002/prot.24312
By:
- Nisbet, Rebecca M.;
- Nuttall, Stewart D.;
- Robert, Remy;
- Caine, Joanne M.;
- Dolezal, Olan;
- Hattarki, Meghan;
- Pearce, Lesley A.;
- Davydova, Natalia;
- Masters, Colin L.;
- Varghese, Jose N.;
- Streltsov, Victor A.
Publication type:
Article
Isolation, kinetic analysis, and structural characterization of an antibody targeting the Bacillus anthracis major spore surface protein BclA.
Published in:
Proteins, 2011, v. 79, n. 4, p. 1306, doi. 10.1002/prot.22971
By:
- Nuttall, Stewart D.;
- Wilkins, Michelle L.;
- Streltsov, Victor A.;
- Pontes-Braz, Luisa;
- Dolezal, Olan;
- Tran, Hung;
- Liu, Chun-Qiang
Publication type:
Article
Shark IgNAR antibody mimotopes target a murine immunoglobulin through extended CDR3 loop structures.
Published in:
Proteins, 2008, v. 71, n. 1, p. 119, doi. 10.1002/prot.21663
By:
- Simmons, David P.;
- Streltsov, Victor A.;
- Dolezal, Olan;
- Hudson, Peter J.;
- Coley, Andrew M.;
- Foley, Michael;
- Proll, David F.;
- Nuttall, Stewart D.
Publication type:
Article
Engineering of an anti-epidermal growth factor receptor antibody to single chain format and labeling by sortase A-mediated protein ligation.
Published in:
Biotechnology & Bioengineering, 2012, v. 109, n. 6, p. 1461, doi. 10.1002/bit.24407
By:
- Madej, Mariusz P.;
- Coia, Gregory;
- Williams, Charlotte C.;
- Caine, Joanne M.;
- Pearce, Lesley A.;
- Attwood, Rebecca;
- Bartone, Nick A.;
- Dolezal, Olan;
- Nisbet, Rebecca M.;
- Nuttall, Stewart D.;
- Adams, Timothy E.
Publication type:
Article
Kinetic Characterization of a Panel of High-Affinity Monoclonal Antibodies Targeting Ricin and Recombinant Re-Formatting for Biosensor Applications.
Published in:
Antibodies (2073-4468), 2014, v. 3, n. 2, p. 215, doi. 10.3390/antib3020215
By:
- Cummins, Michelle;
- Dogovski, Con;
- Robert, Remy;
- Alderton, Malcolm;
- Chong, Damien;
- Proll, David;
- Pontes-Braz, Luisa;
- Raicevic, Anna;
- Hattarki, Meghan;
- Nuttall, Stewart;
- Dolezal, Olan
Publication type:
Article
Shark Variable New Antigen Receptor (V<sub>NAR</sub>) Single Domain Antibody Fragments: Stability and Diagnostic Applications.
Published in:
Antibodies (2073-4468), 2013, v. 2, n. 1, p. 66, doi. 10.3390/antib2010066
By:
- Griffiths, Katherine;
- Dolezal, Olan;
- Parisi, Kathy;
- Angerosa, Julie;
- Dogovski, Con;
- Barraclough, Miles;
- Sanalla, Abdulmonem;
- Casey, Joanne L.;
- González, Iveth;
- Perugini, Matthew A.;
- Nuttall, Stewart;
- Foley, Michael
Publication type:
Article
Most clinical anti-EGFR antibodies do not neutralize both wtEGFR and EGFRvIII activation in glioma.
Published in:
Neuro-Oncology, 2019, v. 21, n. 8, p. 1016, doi. 10.1093/neuonc/noz073
By:
- Greenall, Sameer A;
- McKenzie, Mathew;
- Seminova, Ekatarina;
- Dolezal, Olan;
- Pearce, Lesley;
- Bentley, John;
- Kuchibhotla, Mani;
- Chen, Shengnan C;
- McDonald, Kerrie L;
- Kornblum, Harley I;
- Endersby, Raelene;
- Adams, Timothy E;
- Johns, Terrance G
Publication type:
Article
Single-chain Fv multimers of the anti-neuraminidase antibody NC10: the residue at position 15 in the VL domain of the scFv-0 (VL−VH) molecule is primarily responsible for formation of a tetramer–trimer equilibrium.
Published in:
Protein Engineering, 2003, v. 16, n. 1, p. 47, doi. 10.1093/proeng/gzg006
By:
- Dolezal, Olan;
- De Gori, Ross;
- Walter, Mark;
- Doughty, Larissa;
- Hattarki, Meghan;
- Hudson, Peter J.;
- Kortt, Alexander A.
Publication type:
Article
ScFv multimers of the anti-neuraminidase antibody NC10: shortening of the linker in single-chain Fv fragment assembled in VL to VH orientation drives the formation of dimers, trimers, tetramers and higher molecular mass multimers.
Published in:
Protein Engineering, 2000, v. 13, n. 8, p. 565, doi. 10.1093/protein/13.8.565
By:
- Dolezal, Olan;
- Pearce, Lesley A.;
- Lawrence, Lynne J.;
- McCoy, Airlie J.;
- Hudson, Peter J.;
- Kortt, Alexander A.
Publication type:
Article
8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.
Published in:
Chemistry - A European Journal, 2018, v. 24, n. 8, p. 1922, doi. 10.1002/chem.201704730
By:
- Dennis, Matthew L.;
- Lee, Michael D.;
- Harjani, Jitendra R.;
- Ahmed, Mohamed;
- DeBono, Aaron J.;
- Pitcher, Noel P.;
- Wang, Zhong‐Chang;
- Chhabra, Sandeep;
- Barlow, Nicholas;
- Rahmani, Raphaël;
- Cleary, Ben;
- Dolezal, Olan;
- Hattarki, Meghan;
- Aurelio, Luigi;
- Shonberg, Jeremy;
- Graham, Bim;
- Peat, Thomas S.;
- Baell, Jonathan B.;
- Swarbrick, James D.
Publication type:
Article
Interrogating HIV integrase for compounds that bind- a SAMPL challenge.
Published in:
Journal of Computer-Aided Molecular Design, 2014, v. 28, n. 4, p. 347, doi. 10.1007/s10822-014-9721-7
By:
- Peat, Thomas;
- Dolezal, Olan;
- Newman, Janet;
- Mobley, David;
- Deadman, John
Publication type:
Article
The DINGO dataset: a comprehensive set of data for the SAMPL challenge.
Published in:
Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 5, p. 497, doi. 10.1007/s10822-011-9521-2
By:
- Newman, Janet;
- Dolezal, Olan;
- Fazio, Vincent;
- Caradoc-Davies, Tom;
- Peat, Thomas
Publication type:
Article
Crystal structures of human ENPP1 in apo and bound forms.
Published in:
Acta Crystallographica: Section D, Structural Biology, 2020, v. 76, n. 9, p. 889, doi. 10.1107/S2059798320010505
By:
- Dennis, Matthew L.;
- Newman, Janet;
- Dolezal, Olan;
- Hattarki, Meghan;
- Surjadi, Regina N.;
- Nuttall, Stewart D.;
- Pham, Tam;
- Nebl, Tom;
- Camerino, Michelle;
- Khoo, Poh Sim;
- Monahan, Brendon J.;
- Peat, Thomas S.
Publication type:
Article
Germline humanization of a murine Aβ antibody and crystal structure of the humanized recombinant Fab fragment.
Published in:
Protein Science: A Publication of the Protein Society, 2010, v. 19, n. 2, p. 299, doi. 10.1002/pro.312
By:
- Robert, Remy;
- Streltsov, Victor A.;
- Newman, Janet;
- Pearce, Lesley A.;
- Wark, Kim L.;
- Dolezal, Olan
Publication type:
Article
Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin.
Published in:
Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00330
By:
- Lawrence, Sara L.;
- Feil, Susanne C.;
- Holien, Jessica K.;
- Kuiper, Michael J.;
- Doughty, Larissa;
- Dolezal, Olan;
- Mulhern, Terrence D.;
- Tweten, Rodney K.;
- Parker, MichaelW.
Publication type:
Article
Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin.
Published in:
Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00330
By:
- Lawrence, Sara L.;
- Feil, Susanne C.;
- Holien, Jessica K.;
- Kuiper, Michael J.;
- Doughty, Larissa;
- Dolezal, Olan;
- Mulhern, Terrence D.;
- Tweten, Rodney K.;
- Parker, Michael W.
Publication type:
Article
A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6.
Published in:
PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184278
By:
- Robert, Remy;
- Juglair, Laurent;
- Lim, Ee X.;
- Ang, Caroline;
- Wang, Carl J. H.;
- Ebert, Gregor;
- Dolezal, Olan;
- Mackay, Charles R.
Publication type:
Article
Engineered antibody intervention strategies for Alzheimers disease and related dementias by targeting amyloid and toxic oligomers.
Published in:
PEDS: Protein Engineering, Design & Selection, 2009, v. 22, n. 3, p. 199
By:
- Remy Robert;
- Olan Dolezal;
- Lynne Waddington;
- Meghan K. Hattarki;
- Roberto Cappai;
- Colin L. Masters;
- Peter J. Hudson;
- Kim L. Wark
Publication type:
Article

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