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Impact of menaquinone-4 supplementation on coronary artery calcification and arterial stiffness: an open label single arm study.
Published in:
2016
By:
- Yuji Ikari;
- Sho Torii;
- Atsushi Shioi;
- Toshio Okano;
- Ikari, Yuji;
- Torii, Sho;
- Shioi, Atsushi;
- Okano, Toshio
Publication type:
journal article
UBIAD1 Plays an Essential Role in the Survival of Pancreatic Acinar Cells.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 8, p. 1971, doi. 10.3390/ijms20081971
By:
- Nakagawa, Kimie;
- Fujiwara, Kiyomi;
- Nishimura, Akihiro;
- Murakami, Chinami;
- Kawamoto, Kanaha;
- Ichinose, Chihiro;
- Kunitou, Yumi;
- Suhara, Yoshitomo;
- Okano, Toshio;
- Hasegawa, Hiroshi
Publication type:
Article
Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients.
Published in:
Kidney International, 2010, v. 77, n. 3, p. 232, doi. 10.1038/ki.2009.414
By:
- Komaba, Hirotaka;
- Goto, Shunsuke;
- Fujii, Hideki;
- Hamada, Yasuhiro;
- Kobayashi, Akira;
- Shibuya, Koji;
- Tominaga, Yoshihiro;
- Otsuki, Naoki;
- Nibu, Ken-ichi;
- Nakagawa, Kimie;
- Tsugawa, Naoko;
- Okano, Toshio;
- Kitazawa, Riko;
- Fukagawa, Masafumi
Publication type:
Article
Functional Characterization of the Vitamin K2 Biosynthetic Enzyme UBIAD1.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0125737
By:
- Hirota, Yoshihisa;
- Nakagawa, Kimie;
- Sawada, Natsumi;
- Okuda, Naoko;
- Suhara, Yoshitomo;
- Uchino, Yuri;
- Kimoto, Takashi;
- Funahashi, Nobuaki;
- Kamao, Maya;
- Tsugawa, Naoko;
- Okano, Toshio
Publication type:
Article
Vitamin K2 Biosynthetic Enzyme, UBIAD1 Is Essential for Embryonic Development of Mice.
Published in:
PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104078
By:
- Nakagawa, Kimie;
- Sawada, Natsumi;
- Hirota, Yoshihisa;
- Uchino, Yuri;
- Suhara, Yoshitomo;
- Hasegawa, Tomoka;
- Amizuka, Norio;
- Okamoto, Tadashi;
- Tsugawa, Naoko;
- Kamao, Maya;
- Funahashi, Nobuaki;
- Okano, Toshio
Publication type:
Article
Liver-Specific γ-Glutamyl Carboxylase-Deficient Mice Display Bleeding Diathesis and Short Life Span.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088643
By:
- Azuma, Kotaro;
- Tsukui, Tohru;
- Ikeda, Kazuhiro;
- Shiba, Sachiko;
- Nakagawa, Kimie;
- Okano, Toshio;
- Urano, Tomohiko;
- Horie-Inoue, Kuniko;
- Ouchi, Yasuyoshi;
- Ikawa, Masahito;
- Inoue, Satoshi
Publication type:
Article
Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme.
Published in:
Nature, 2010, v. 468, n. 7320, p. 117, doi. 10.1038/nature09464
By:
- Nakagawa, Kimie;
- Hirota, Yoshihisa;
- Sawada, Natsumi;
- Yuge, Naohito;
- Watanabe, Masato;
- Uchino, Yuri;
- Okuda, Naoko;
- Shimomura, Yuka;
- Suhara, Yoshitomo;
- Okano, Toshio
Publication type:
Article
Low calcium intake is associated with increased bone resorption in postmenopausal Japanese women: Yokogoshi Study.
Published in:
Public Health Nutrition, 2009, v. 12, n. 12, p. 2366, doi. 10.1017/S1368980009005084
By:
- Nakamura, Kazutoshi;
- Saito, Toshiko;
- Yoshihara, Akihiro;
- Ishikawa, Miki;
- Tsuchiya, Yasuo;
- Oshiki, Rieko;
- Kobayashi, Ryosaku;
- Maruyama, Keiko;
- Hyodo, Keiko;
- Nashimoto, Mitsue;
- Tsugawa, Naoko;
- Okano, Toshio;
- Oyama, Mari;
- Yamamoto, Masaharu
Publication type:
Article
Surveillance evaluation of the standardization of assay values for serum total 25-hydroxyvitamin D concentration in Japan.
Published in:
2018
By:
- Ihara, Hiroshi;
- Kiuchi, Sachiko;
- Ishige, Takayuki;
- Nishimura, Motoi;
- Matsushita, Kazuyuki;
- Satoh, Mamoru;
- Nomura, Fumio;
- Yamashita, Mine;
- Kitajima, Isao;
- Tsugawa, Naoko;
- Okano, Toshio;
- Hirota, Kouichi;
- Miura, Masakazu;
- Totani, Masayuki;
- Hashizume, Naotaka
Publication type:
journal article
22-Oxa-1α,25-dihydroxyvitamin D<inf>3</inf> inhibits metastasis and angiogenesis in lung cancer.
Published in:
Carcinogenesis, 2005, v. 26, n. 6, p. 1044, doi. 10.1093/carcin/bgi049
By:
- Kimie Nakagawa;
- Yuko Sasaki;
- Shigeaki Kato;
- Noboru Kubodera;
- Toshio Okano
Publication type:
Article
1a,25-Dihydroxyvitamin D3 is a preventive factor in the metastasis of lung cancer.
Published in:
Carcinogenesis, 2005, v. 26, n. 2, p. 429
By:
- Kimie Nakagawa;
- Akihiko Kawaura;
- Shigeaki Kato;
- Eiji Takeda;
- Toshio Okano
Publication type:
Article
25-Hydroxyvitamin D profiles and maternal bone mass during pregnancy and lactation in Japanese women.
Published in:
2020
By:
- Yoshikata, Hiromi;
- Tsugawa, Naoko;
- Watanabe, Yuna;
- Tsuburai, Taku;
- Chaki, Osamu;
- Hirahara, Fumiki;
- Miyagi, Etsuko;
- Sakakibara, Hideya;
- Uenishi, Kazuhiro;
- Okano, Toshio
Publication type:
journal article
Optimal vitamin D intake for preventing serum 25-hydroxyvitamin D insufficiency in young Japanese women.
Published in:
2018
By:
- Ohta, Hiroaki;
- Kuroda, Tatsuhiko;
- Tsugawa, Naoko;
- Onoe, Yoshiko;
- Okano, Toshio;
- Shiraki, Masataka
Publication type:
journal article
Association between vitamin D status and serum parathyroid hormone concentration and calcaneal stiffness in Japanese adolescents: sex differences in susceptibility to vitamin D deficiency.
Published in:
2016
By:
- Tsugawa, Naoko;
- Uenishi, Kazuhiro;
- Ishida, Hiromi;
- Ozaki, Reo;
- Takase, Tomoki;
- Minekami, Takuya;
- Uchino, Yuri;
- Kamao, Maya;
- Okano, Toshio
Publication type:
journal article
Effects of Fok-I polymorphism in vitamin D receptor gene on serum 25-hydroxyvitamin D, bone-specific alkaline phosphatase and calcaneal quantitative ultrasound parameters in young adults.
Published in:
Asia Pacific Journal of Clinical Nutrition, 2015, v. 24, n. 2, p. 329, doi. 10.6133//apjcn.2015.24.2.01
By:
- Rieko Tanabe;
- Yuka Kawamura;
- Naoko Tsugawa;
- Mayu Haraikawa;
- Natsuko Sogabe;
- Toshio Okano;
- Takayuki Hosoi;
- Masae Goseki-Sone
Publication type:
Article
Effects of gamma-glutamyl carboxylase gene polymorphism (R325Q) on the association between dietary vitamin K intake and gamma-carboxylation of osteocalcin in young adults.
Published in:
2013
By:
- Haraikawa, Mayu;
- Tsugawa, Naoko;
- Sogabe, Natsuko;
- Tanabe, Rieko;
- Kawamura, Yuka;
- Okano, Toshio;
- Hosoi, Takayuki;
- Goseki-Sone, Masae
Publication type:
journal article
Effects of gamma-glutamyl carboxylase gene polymorphism (R325Q) on the association between dietary vitamin K intake and gamma-carboxylation of osteocalcin in young adults.
Published in:
Asia Pacific Journal of Clinical Nutrition, 2013, v. 22, n. 4, p. 646, doi. 10.6133/apjcn.2013.22.4.01
By:
- Mayu Haraikawa;
- Naoko Tsugawa;
- Natsuko Sogabe;
- Rieko Tanabe;
- Yuka Kawamura;
- Toshio Okano;
- Takayuki Hosoi;
- Masae Goseki-Sone
Publication type:
Article
High prevalence of hypovitaminosis D and K in patients with hip fracture.
Published in:
2011
By:
- Nakano, Tetsuo;
- Tsugawa, Naoko;
- Kuwabara, Akiko;
- Kamao, Maya;
- Tanaka, Kiyoshi;
- Okano, Toshio
Publication type:
journal article
Hypovitaminosis D and K are highly prevalent and independent of overall malnutrition in the institutionalized elderly.
Published in:
Asia Pacific Journal of Clinical Nutrition, 2010, v. 19, n. 1, p. 49
By:
- Kuwabara, Akiko;
- Himeno, Masako;
- Tsugawa, Naoko;
- Kamao, Maya;
- Fujii, Minori;
- Kawai, Nobuko;
- Fukuda, Miyuki;
- Ogawa, Yoko;
- Kido, Shoko;
- Okano, Toshio;
- Tanaka, Kiyoshi
Publication type:
Article
Asymmetric catalytic ene-cyclization approach to 2-fluoro-19-nor-1,25-dihydroxyvitamin D3 A-ring analog with significant transactivation activity.
Published in:
Chirality, 2001, v. 13, n. 7, p. 366, doi. 10.1002/chir.1046
By:
- Mikami, Koichi;
- Ohba, Shiho;
- Ohmura, Hirofumi;
- Kubodera, Noboru;
- Nakagawa, Kimie;
- Okano, Toshio
Publication type:
Article
The UBIAD1 Prenyltransferase Links Menaquinone-4 Synthesis to Cholesterol Metabolic Enzymes.
Published in:
Human Mutation, 2013, v. 34, n. 7, p. 1046, doi. 10.1002/humu.22334
By:
- Nickerson, Michael L.;
- Bosley, Allen D.;
- Weiss, Jayne S.;
- Kostiha, Brittany N.;
- Hirota, Yoshihisa;
- Brandt, Wolfgang;
- Esposito, Dominic;
- Kinoshita, Shigeru;
- Wessjohann, Ludger;
- Morham, Scott G.;
- Andresson, Thorkell;
- Kruth, Howard S.;
- Okano, Toshio;
- Dean, Michael
Publication type:
Article
The UBIAD1 Prenyltransferase Links Menaquione-4 Synthesis to Cholesterol Metabolic Enzymes.
Published in:
Human Mutation, 2013, v. 34, n. 2, p. 317, doi. 10.1002/humu.22230
By:
- Nickerson, Michael L.;
- Bosley, Allen D.;
- Weiss, Jayne S.;
- Kostiha, Brittany N.;
- Hirota, Yoshihisa;
- Brandt, Wolfgang;
- Esposito, Dominic;
- Kinoshita, Shigeru;
- Wessjohann, Ludger;
- Morham, Scott G.;
- Andresson, Thorkell;
- Kruth, Howard S.;
- Okano, Toshio;
- Dean, Michael
Publication type:
Article
Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice.
Published in:
PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0199856
By:
- Hirota, Yoshihisa;
- Nakagawa, Kimie;
- Isomoto, Keigo;
- Sakaki, Toshiyuki;
- Kubodera, Noboru;
- Kamao, Maya;
- Osakabe, Naomi;
- Suhara, Yoshitomo;
- Okano, Toshio
Publication type:
Article
Elevated Fibroblast Growth Factor 23 Exerts Its Effects on Placenta and Regulates Vitamin D Metabolism in Pregnancy of Hyp Mice.
Published in:
Journal of Bone & Mineral Research, 2014, v. 29, n. 7, p. 1627, doi. 10.1002/jbmr.2186
By:
- Ohata, Yasuhisa;
- Yamazaki, Miwa;
- Kawai, Masanobu;
- Tsugawa, Naoko;
- Tachikawa, Kanako;
- Koinuma, Tomoko;
- Miyagawa, Kazuaki;
- Kimoto, Akihito;
- Nakayama, Masahiro;
- Namba, Noriyuki;
- Yamamoto, Hironori;
- Okano, Toshio;
- Ozono, Keiichi;
- Michigami, Toshimi
Publication type:
Article
Vitamin D insufficiency defined by serum 25-hydroxyvitamin D and parathyroid hormone before and after oral vitamin D₃ load in Japanese subjects.
Published in:
2011
By:
- Okazaki, Ryo;
- Sugimoto, Toshitsugu;
- Kaji, Hiroshi;
- Fujii, Yoshio;
- Shiraki, Masataka;
- Inoue, Daisuke;
- Endo, Itsuro;
- Okano, Toshio;
- Hirota, Takako;
- Kurahashi, Issei;
- Matsumoto, Toshio
Publication type:
journal article
High level of serum undercarboxylated osteocalcin in patients with incident fractures during bisphosphonate treatment.
Published in:
2010
By:
- Shiraki, Masataka;
- Yamazaki, Yasushi;
- Shiraki, Yumiko;
- Hosoi, Takayuki;
- Tsugawa, Naoko;
- Okano, Toshio
Publication type:
journal article
Effect of vitamin D supplementation in the institutionalized elderly.
Published in:
2009
By:
- Himeno, Masako;
- Tsugawa, Naoko;
- Kuwabara, Akiko;
- Fujii, Minori;
- Kawai, Nobuko;
- Kato, Yuzuru;
- Kihara, Noriko;
- Toyoda, Tomoko;
- Kishimoto, Masami;
- Ogawa, Yoko;
- Kido, Shoko;
- Noike, Toshiaki;
- Okano, Toshio;
- Tanaka, Kiyoshi
Publication type:
journal article
The impact of lifestyle factors on serum 25-hydroxyvitamin D levels: a cross-sectional study in Japanese women aged 19-25 years.
Published in:
2009
By:
- Ohta, Hiroaki;
- Kuroda, Tatsuhiko;
- Onoe, Yoshiko;
- Orito, Seiya;
- Ohara, Mami;
- Kume, Miyoko;
- Harada, Akiko;
- Tsugawa, Naoko;
- Okano, Toshio;
- Sasaki, Satoshi
Publication type:
journal article
Low plasma phylloquinone concentration is associated with high incidence of vertebral fracture in Japanese women.
Published in:
Journal of Bone & Mineral Metabolism, 2008, v. 26, n. 1, p. 79, doi. 10.1007/s00774-007-0790-8
By:
- Naoko Tsugawa;
- Masataka Shiraki;
- Yoshitomo Suhara;
- Maya Kamao;
- Reo Ozaki;
- Kiyoshi Tanaka;
- Toshio Okano
Publication type:
Article

Found: 29

Impact of menaquinone-4 supplementation on coronary artery calcification and arterial stiffness: an open label single arm study.

UBIAD1 Plays an Essential Role in the Survival of Pancreatic Acinar Cells.

Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients.

Functional Characterization of the Vitamin K<sub>2</sub> Biosynthetic Enzyme UBIAD1.

Vitamin K<sub>2</sub> Biosynthetic Enzyme, UBIAD1 Is Essential for Embryonic Development of Mice.

Liver-Specific γ-Glutamyl Carboxylase-Deficient Mice Display Bleeding Diathesis and Short Life Span.

Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme.

Low calcium intake is associated with increased bone resorption in postmenopausal Japanese women: Yokogoshi Study.

Surveillance evaluation of the standardization of assay values for serum total 25-hydroxyvitamin D concentration in Japan.

22-Oxa-1α,25-dihydroxyvitamin D<inf>3</inf> inhibits metastasis and angiogenesis in lung cancer.

1a,25-Dihydroxyvitamin D3 is a preventive factor in the metastasis of lung cancer.

25-Hydroxyvitamin D profiles and maternal bone mass during pregnancy and lactation in Japanese women.

Optimal vitamin D intake for preventing serum 25-hydroxyvitamin D insufficiency in young Japanese women.

Association between vitamin D status and serum parathyroid hormone concentration and calcaneal stiffness in Japanese adolescents: sex differences in susceptibility to vitamin D deficiency.

Effects of Fok-I polymorphism in vitamin D receptor gene on serum 25-hydroxyvitamin D, bone-specific alkaline phosphatase and calcaneal quantitative ultrasound parameters in young adults.

Effects of gamma-glutamyl carboxylase gene polymorphism (R325Q) on the association between dietary vitamin K intake and gamma-carboxylation of osteocalcin in young adults.

Effects of gamma-glutamyl carboxylase gene polymorphism (R325Q) on the association between dietary vitamin K intake and gamma-carboxylation of osteocalcin in young adults.

High prevalence of hypovitaminosis D and K in patients with hip fracture.

Hypovitaminosis D and K are highly prevalent and independent of overall malnutrition in the institutionalized elderly.

Asymmetric catalytic ene-cyclization approach to 2-fluoro-19-nor-1,25-dihydroxyvitamin D<sub>3</sub> A-ring analog with significant transactivation activity.

The UBIAD1 Prenyltransferase Links Menaquinone-4 Synthesis to Cholesterol Metabolic Enzymes.

The UBIAD1 Prenyltransferase Links Menaquione-4 Synthesis to Cholesterol Metabolic Enzymes.

Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice.

Elevated Fibroblast Growth Factor 23 Exerts Its Effects on Placenta and Regulates Vitamin D Metabolism in Pregnancy of Hyp Mice.

Vitamin D insufficiency defined by serum 25-hydroxyvitamin D and parathyroid hormone before and after oral vitamin D₃ load in Japanese subjects.

High level of serum undercarboxylated osteocalcin in patients with incident fractures during bisphosphonate treatment.

Effect of vitamin D supplementation in the institutionalized elderly.

The impact of lifestyle factors on serum 25-hydroxyvitamin D levels: a cross-sectional study in Japanese women aged 19-25 years.

Low plasma phylloquinone concentration is associated with high incidence of vertebral fracture in Japanese women.