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TLR agonists regulate PDGF-B production and cell proliferation through TGF-β/type I IFN crosstalk.
Published in:
EMBO Journal, 2005, v. 24, n. 23, p. 4071, doi. 10.1038/sj.emboj.7600867
By:
- Chow, Edward K;
- O'Connell, Ryan M;
- Schilling, Stephen;
- Wang, Xiao-Fan;
- Fu, Xin-Yuan;
- Cheng, Genhong
Publication type:
Article
Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease.
Published in:
PLoS Genetics, 2019, v. 15, n. 2, p. 1, doi. 10.1371/journal.pgen.1007970
By:
- Runtsch, Marah C.;
- Nelson, Morgan C.;
- Lee, Soh-Hyun;
- Voth, Warren;
- Alexander, Margaret;
- Hu, Ruozhen;
- Wallace, Jared;
- Petersen, Charisse;
- Panic, Vanja;
- Villanueva, Claudio J.;
- Evason, Kimberley J.;
- Bauer, Kaylyn M.;
- Mosbruger, Timothy;
- Boudina, Sihem;
- Bronner, Mary;
- Round, June L.;
- Drummond, Micah J.;
- O’Connell, Ryan M.
Publication type:
Article
Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system.
Published in:
Glia, 2020, v. 68, n. 11, p. 2345, doi. 10.1002/glia.23844
By:
- Mangale, Vrushali;
- Syage, Amber R.;
- Ekiz, H. Atakan;
- Skinner, Dominic D.;
- Cheng, Yuting;
- Stone, Colleen L.;
- Brown, R. Marshall;
- O'Connell, Ryan M.;
- Green, Kim N.;
- Lane, Thomas E.
Publication type:
Article
miR-aculous new avenues for cancer immunotherapy.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.929677
By:
- Tang, William W.;
- Bauer, Kaylyn M.;
- Barba, Cindy;
- Ekiz, Huseyin Atakan;
- O’Connell, Ryan M.
Publication type:
Article
A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22923-5
By:
- Huffaker, Thomas B.;
- Ekiz, H. Atakan;
- Barba, Cindy;
- Lee, Soh-Hyun;
- Runtsch, Marah C.;
- Nelson, Morgan C.;
- Bauer, Kaylyn M.;
- Tang, William W.;
- Mosbruger, Timothy L.;
- Cox, James E.;
- Round, June L.;
- Voth, Warren P.;
- O'Connell, Ryan M.
Publication type:
Article
MiR-23b is a safeguard against autoimmunity.
Published in:
Nature Medicine, 2012, v. 18, n. 7, p. 1009, doi. 10.1038/nm.2849
By:
- Hu, Ruozhen;
- O'Connell, Ryan M
Publication type:
Article
MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection.
Published in:
Scientific Reports, 2015, p. 8642, doi. 10.1038/ncomms9642
By:
- Kubinak, Jason L.;
- Stephens, W. Zac;
- Soto, Ray;
- Petersen, Charisse;
- Chiaro, Tyson;
- Gogokhia, Lasha;
- Bell, Rickesha;
- Ajami, Nadim J.;
- Petrosino, Joseph F.;
- Morrison, Linda;
- Potts, Wayne K.;
- Jensen, Peter E.;
- O'Connell, Ryan M.;
- Round, June L.
Publication type:
Article
Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis.
Published in:
PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0135142
By:
- Lochhead, Robert B.;
- Zachary, James F.;
- Dalla Rosa, Luciana;
- Ma, Ying;
- Weis, John H.;
- O’Connell, Ryan M.;
- Weis, Janis J.
Publication type:
Article
Targeting Human MicroRNA Genes Using Engineered Tal-Effector Nucleases (TALENs)
Published in:
PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063074
By:
- Hu, Ruozhen;
- Wallace, Jared;
- Dahlem, Timothy J.;
- Grunwald, David Jonah;
- O'Connell, Ryan M.
Publication type:
Article
Lentiviral Vector Delivery of Human Interleukin-7 (hIL-7) to Human Immune System (HIS) Mice Expands T Lymphocyte Populations.
Published in:
PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012009
By:
- O'Connell, Ryan M.;
- Balazs, Alejandro B.;
- Rao, Dinesh S.;
- Kivork, Christine;
- Lili Yang;
- Baltimore, David
Publication type:
Article
MicroRNAs and the regulation of intestinal homeostasis.
Published in:
Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00347
By:
- Runtsch, Marah C.;
- Round, June L.;
- O'Connell, Ryan M.
Publication type:
Article
The miR-26b-5p/KPNA2 Axis Is an Important Regulator of Burkitt Lymphoma Cell Growth.
Published in:
Cancers, 2020, v. 12, n. 6, p. 1464, doi. 10.3390/cancers12061464
By:
- Niu, Fubiao;
- Kazimierska, Marta;
- Nolte, Ilja M.;
- Terpstra, Miente Martijn;
- de Jong, Debora;
- Koerts, Jasper;
- van der Sluis, Tineke;
- Rutgers, Bea;
- O'Connell, Ryan M.;
- Kok, Klaas;
- van den Berg, Anke;
- Dzikiewicz-Krawczyk, Agnieszka;
- Kluiver, Joost
Publication type:
Article
No small matter: emerging roles for exosomal miRNAs in the immune system.
Published in:
FEBS Journal, 2022, v. 289, n. 14, p. 4021, doi. 10.1111/febs.16052
By:
- Bauer, Kaylyn M.;
- Round, June L.;
- O'Connell, Ryan M.
Publication type:
Article
Physiological and pathological roles for microRNAs in the immune system.
Published in:
2010
By:
- O'Connell, Ryan M.;
- Rao, Dinesh S.;
- Chaudhuri, Aadel A.;
- Baltimore, David
Publication type:
journal article
MicroRNA control in the development of systemic autoimmunity
Published in:
Arthritis Research & Therapy, 2013, v. 15, n. 1, p. 202, doi. 10.1186/ar4131
By:
- Hu, Ruozhen;
- O’Connell, Ryan M
Publication type:
Article
A MyD88-dependent IFNγR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge.
Published in:
Cell Research, 2011, v. 21, n. 7, p. 1068, doi. 10.1038/cr.2011.59
By:
- Pietras, Eric M.;
- Miller, Lloyd S.;
- Johnson, Carl T.;
- O'Connell, Ryan M.;
- Dempsey, Paul W.;
- Genhong Cheng
Publication type:
Article
CIPR: a web-based R/shiny app and R package to annotate cell clusters in single cell RNA sequencing experiments.
Published in:
BMC Bioinformatics, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12859-020-3538-2
By:
- Ekiz, H. Atakan;
- Conley, Christopher J.;
- Stephens, W. Zac;
- O'Connell, Ryan M.
Publication type:
Article
MicroRNAs: new regulators of immune cell development and function.
Published in:
Nature Immunology, 2008, v. 9, n. 8, p. 839, doi. 10.1038/ni.f.209
By:
- Baltimore, David;
- Boldin, Mark P;
- O'Connell, Ryan M;
- Rao, Dinesh S;
- Taganov, Konstantin D
Publication type:
Article
MicroRNAs: At the Interface of Metabolic Pathways and Inflammatory Responses by Macrophages.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.01797
By:
- Nelson, Morgan C.;
- O'Connell, Ryan M.
Publication type:
Article
MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection.
Published in:
Nature Communications, 2015, v. 6, n. 10, p. 8642, doi. 10.1038/ncomms9642
By:
- Kubinak, Jason L.;
- Stephens, W. Zac;
- Soto, Ray;
- Petersen, Charisse;
- Chiaro, Tyson;
- Gogokhia, Lasha;
- Bell, Rickesha;
- Ajami, Nadim J.;
- Petrosino, Joseph F.;
- Morrison, Linda;
- Potts, Wayne K.;
- Jensen, Peter E.;
- O'Connell, Ryan M.;
- Round, June L.
Publication type:
Article
Exosome-delivered microRNAs modulate the inflammatory response to endotoxin.
Published in:
Nature Communications, 2015, v. 6, n. 6, p. 7321, doi. 10.1038/ncomms8321
By:
- Alexander, Margaret;
- Hu, Ruozhen;
- Runtsch, Marah C.;
- Kagele, Dominique A.;
- Mosbruger, Timothy L.;
- Tolmachova, Tanya;
- Seabra, Miguel C.;
- Round, June L.;
- Ward, Diane M.;
- O'Connell, Ryan M.
Publication type:
Article
A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice.
Published in:
Science Translational Medicine, 2017, v. 9, n. 380, p. 1, doi. 10.1126/scitranslmed.aaf9044
By:
- Chiaro, Tyson R.;
- Soto, Ray;
- Stephens, W. Zac;
- Kubinak, Jason L.;
- Petersen, Charisse;
- Gogokhia, Lasha;
- Bell, Rickesha;
- Delgado, Julio C.;
- Cox, James;
- Voth, Warren;
- Brown, Jessica;
- Stillman, David J.;
- O'Connell, Ryan M.;
- Tebo, Anne E.;
- Round, June L.
Publication type:
Article
MicroRNA-146a Provides Feedback Regulation of Lyme Arthritis but Not Carditis during Infection with <i>Borrelia burgdorferi</i>.
Published in:
PLoS Pathogens, 2014, v. 10, n. 6, p. 1, doi. 10.1371/journal.ppat.1004212
By:
- Lochhead, Robert B.;
- Ma, Ying;
- Zachary, James F.;
- Baltimore, David;
- Zhao, Jimmy L.;
- Weis, John H.;
- O'Connell, Ryan M.;
- Weis, Janis J.
Publication type:
Article
Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs.
Published in:
NAR Cancer, 2023, v. 5, n. 2, p. 1, doi. 10.1093/narcan/zcad027
By:
- Arnesen, Spencer;
- Polaski, Jacob T.;
- Blanchard, Zannel;
- Osborne, Kyle S.;
- Welm, Alana L.;
- O'Connell, Ryan M.;
- Gertz, Jason
Publication type:
Article
Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth.
Published in:
PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153689
By:
- Wallace, Jared;
- Hu, Ruozhen;
- Mosbruger, Timothy L.;
- Dahlem, Timothy J.;
- Stephens, W. Zac;
- Rao, Dinesh S.;
- Round, June L.;
- O’Connell, Ryan M.
Publication type:
Article
MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic disease.
Published in:
2016
By:
- Dickey, Laura L.;
- Worne, Colleen L.;
- Glover, Jessica L.;
- Lane, Thomas E.;
- O'Connell, Ryan M.
Publication type:
journal article
miRNA-1 promotes acute myeloid leukemia cell pathogenesis through metabolic regulation.
Published in:
Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1192799
By:
- Ghazaryan, Arevik;
- Wallace, Jared A.;
- Tang, William W.;
- Barba, Cindy;
- Soh-Hyun Lee;
- Bauer, Kaylyn M.;
- Nelson, Morgan C.;
- Kim, Carissa N.;
- Stubben, Chris;
- Voth, Warren P.;
- Rao, Dinesh S.;
- O'Connell, Ryan M.
Publication type:
Article
Noncoding RNAs and chronic inflammation: Micro-managing the fire within.
Published in:
BioEssays, 2015, v. 37, n. 9, p. 1005, doi. 10.1002/bies.201500054
By:
- Alexander, Margaret;
- O'Connell, Ryan M.
Publication type:
Article
Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy.
Published in:
Aging Cell, 2021, v. 20, n. 9, p. 1, doi. 10.1111/acel.13448
By:
- Fix, Dennis K.;
- Ekiz, H. Atakan;
- Petrocelli, Jonathan J.;
- Mckenzie, Alec M.;
- Mahmassani, Ziad S.;
- O'Connell, Ryan M.;
- Drummond, Micah J.
Publication type:
Article
Absence of MyD88 from Skeletal Muscle Protects Female Mice from Inactivity-Induced Adiposity and Insulin Resistance.
Published in:
2020
By:
- Mahmassani, Ziad S.;
- Reidy, Paul T.;
- McKenzie, Alec I.;
- Petrocelli, Jonathan J.;
- Matthews, O'Connor;
- Hart, Naomi M.;
- Ferrara, Patrick J.;
- O'Connell, Ryan M.;
- Funai, Katsuhiko;
- Drummond, Micah J.;
- de Hart, Naomi M
Publication type:
journal article

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