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Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy.
Published in:
Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 8, p. 5377, doi. 10.1007/s00432-022-04440-0
By:
- Davern, Maria;
- Donlon, Noel E.;
- O'Connell, Fiona;
- Gaughan, Caoimhe;
- O'Donovan, Cillian;
- McGrath, Jason;
- Sheppard, Andrew D.;
- Hayes, Conall;
- King, Ross;
- Temperley, Hugo;
- MacLean, Michael;
- Bulter, Christine;
- Bhardwaj, Anshul;
- Moore, Jenny;
- Donohoe, Claire;
- Ravi, Narayanasamy;
- Conroy, Melissa J.;
- Reynolds, John V.;
- Lysaght, Joanne
Publication type:
Article
The Effect of Tuberculosis Antimicrobials on the Immunometabolic Profiles of Primary Human Macrophages Stimulated with Mycobacterium tuberculosis.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12189, doi. 10.3390/ijms222212189
By:
- Cahill, Christina;
- Cox, Dónal J.;
- O'Connell, Fiona;
- Basdeo, Sharee A.;
- Gogan, Karl M.;
- Ó'Maoldomhnaigh, Cilian;
- O'Sullivan, Jacintha;
- Keane, Joseph;
- Phelan, James J.
Publication type:
Article
The Iron Chelator Desferrioxamine Increases the Efficacy of Bedaquiline in Primary Human Macrophages Infected with BCG.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2938, doi. 10.3390/ijms22062938
By:
- Cahill, Christina;
- O'Connell, Fiona;
- Gogan, Karl M.;
- Cox, Donal J.;
- Basdeo, Sharee A.;
- O'Sullivan, Jacintha;
- Gordon, Stephen V.;
- Keane, Joseph;
- Phelan, James J.;
- Battistoni, Andrea
Publication type:
Article
Obesity, Dietary Fats, and Gastrointestinal Cancer Risk-Potential Mechanisms Relating to Lipid Metabolism and Inflammation.
Published in:
Metabolites (2218-1989), 2024, v. 14, n. 1, p. 42, doi. 10.3390/metabo14010042
By:
- Mitchelson, Kathleen A. J.;
- O'Connell, Fiona;
- O'Sullivan, Jacintha;
- Roche, Helen M.
Publication type:
Article
Metformin is a metabolic modulator and radiosensitiser in rectal cancer.
Published in:
Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1216911
By:
- Buckley, CroíE.;
- O'Brien, Rebecca M.;
- Nugent, Timothy S.;
- Donlon, Noel E.;
- O'Connell, Fiona;
- Reynolds, John V.;
- Hafeez, Adnan;
- O'Ríordáin, Diarmuid S.;
- Hannon, Robert A.;
- Neary, Paul;
- Kalbassi, Reza;
- Mehigan, Brian J.;
- McCormick, Paul H.;
- Dunne, Cara;
- Kelly, Michael E.;
- Larkin, John O.;
- O'Sullivan, Jacintha;
- Lynam-Lennon, Niamh
Publication type:
Article
The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.823225
By:
- Donlon, Noel E.;
- Davern, Maria;
- Sheppard, Andrew D.;
- O'Connell, Fiona;
- Dunne, Margaret R.;
- Hayes, Conall;
- Mylod, Eimear;
- Ramjit, Sinead;
- Temperley, Hugo;
- Mac Lean, Michael;
- Cotter, Gillian;
- Bhardwaj, Anshul;
- Butler, Christine;
- Conroy, Melissa J.;
- O'Sullivan, Jacintha;
- Ravi, Narayanasamy;
- Donohoe, Claire L.;
- Reynolds, John V.;
- Lysaght, Joanne
Publication type:
Article
THE ULTIMATE SURVEY.
Published in:
Collected Magazine, 2019, n. 25, p. 60
By:
- WEBSTER, TRISH;
- O'CONNELL, FIONA
Publication type:
Article
Combining 1,4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors.
Published in:
2020
By:
- Kennedy, Susan A.;
- Morrissey, Maria E.;
- Dunne, Margaret R.;
- O'Connell, Fiona;
- Butler, Clare T.;
- Cathcart, Mary-Clare;
- Buckley, Amy M.;
- Mehigan, Brian J.;
- Larkin, John O.;
- McCormick, Paul;
- Kennedy, Breandán N.;
- O'Sullivan, Jacintha
Publication type:
journal article
Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients.
Published in:
Cancer Immunology, Immunotherapy, 2023, v. 72, n. 1, p. 55, doi. 10.1007/s00262-022-03228-y
By:
- Davern, Maria;
- Donlon, Noel E.;
- O'Connell, Fiona;
- Gaughan, Caoimhe;
- O'Donovan, Cillian;
- Habash, Mohammed;
- Sheppard, Andrew D.;
- MacLean, Michael;
- Dunne, Margaret R.;
- Moore, Jenny;
- Temperley, Hugo;
- Conroy, Melissa J.;
- Butler, Christine;
- Bhardwaj, Anshul;
- Ravi, Narayanasamy;
- Donohoe, Claire L.;
- Reynolds, John V.;
- Lysaght, Joanne
Publication type:
Article
Energy Metabolism, Metabolite, and Inflammatory Profiles in Human Ex Vivo Adipose Tissue Are Influenced by Obesity Status, Metabolic Dysfunction, and Treatment Regimes in Patients with Oesophageal Adenocarcinoma.
Published in:
Cancers, 2023, v. 15, n. 6, p. 1681, doi. 10.3390/cancers15061681
By:
- O'Connell, Fiona;
- Mylod, Eimear;
- Donlon, Noel E.;
- Heeran, Aisling B.;
- Butler, Christine;
- Bhardwaj, Anshul;
- Ramjit, Sinead;
- Durand, Michael;
- Lambe, Gerard;
- Tansey, Paul;
- Welartne, Ivan;
- Sheahan, Kevin P.;
- Yin, Xiaofei;
- Donohoe, Claire L.;
- Ravi, Narayanasamy;
- Dunne, Margaret R.;
- Brennan, Lorraine;
- Reynolds, John V.;
- Roche, Helen M.;
- O'Sullivan, Jacintha
Publication type:
Article
The Omentum in Obesity-Associated Cancer: A Hindrance to Effective Natural Killer Cell Migration towards Tumour Which Can Be Overcome by CX3CR1 Antagonism.
Published in:
Cancers, 2022, v. 14, n. 1, p. 64, doi. 10.3390/cancers14010064
By:
- Mylod, Eimear;
- O'Connell, Fiona;
- Donlon, Noel E.;
- Butler, Christine;
- Reynolds, John V.;
- Lysaght, Joanne;
- Conroy, Melissa J.
Publication type:
Article
The Prognostic Value of the Lymph Node in Oesophageal Adenocarcinoma; Incorporating Clinicopathological and Immunological Profiling.
Published in:
Cancers, 2021, v. 13, n. 16, p. 4005, doi. 10.3390/cancers13164005
By:
- Donlon, Noel E.;
- Davern, Maria;
- Sheppard, Andrew;
- Power, Robert;
- O'Connell, Fiona;
- Heeran, Aisling B.;
- King, Ross;
- Hayes, Conall;
- Bhardwaj, Anshul;
- Phelan, James J.;
- Dunne, Margaret R.;
- Ravi, Narayanasamy;
- Donohoe, Claire L.;
- O'Sullivan, Jacintha;
- Reynolds, John V.;
- Lysaght, Joanne
Publication type:
Article
Linking Circulating Serum Proteins with Clinical Outcomes in Esophageal Adenocarcinoma—An Emerging Role for Chemokines.
Published in:
Cancers, 2020, v. 12, n. 11, p. 3356, doi. 10.3390/cancers12113356
By:
- Donlon, Noel E.;
- Sheppard, Andrew;
- Davern, Maria;
- O'Connell, Fiona;
- Phelan, James J.;
- Power, Robert;
- Nugent, Timothy;
- Dinneen, Kate;
- Aird, John;
- Greene, John;
- Nevins Selvadurai, Paul;
- Bhardwaj, Anshul;
- Foley, Emma K.;
- Ravi, Narayanasamy;
- Donohoe, Claire L.;
- Reynolds, John V.;
- Lysaght, Joanne;
- O'Sullivan, Jacintha;
- Dunne, Margaret R.
Publication type:
Article
High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells.
Published in:
Cancers, 2020, v. 12, n. 10, p. 2950, doi. 10.3390/cancers12102950
By:
- Slater, Kayleigh;
- Heeran, Aisling B.;
- Garcia-Mulero, Sandra;
- Kalirai, Helen;
- Sanz-Pamplona, Rebeca;
- Rahman, Arman;
- Al-Attar, Nebras;
- Helmi, Mays;
- O'Connell, Fiona;
- Bosch, Rosa;
- Portela, Anna;
- Villanueva, Alberto;
- Gallagher, William M.;
- Jensen, Lasse D.;
- Piulats, Josep M.;
- Coupland, Sarah E.;
- O'Sullivan, Jacintha;
- Kennedy, Breandán N.
Publication type:
Article
Clinical Characterization of New-Onset Chronic Musculoskeletal Pain in Long COVID: A Cross-Sectional Study.
Published in:
Journal of Pain Research, 2024, v. 17, p. 2531, doi. 10.2147/JPR.S466294
By:
- Khoja, Omar;
- Silva-Passadouro, Bárbara;
- Cristescu, Elena;
- McEwan, Katie;
- Doherty, Derek;
- O'Connell, Fiona;
- Ponchel, Frederique;
- Mulvey, Matthew;
- Astill, Sarah;
- Tan, Ai Lyn;
- Sivan, Manoj
Publication type:
Article
Human Macrophages Activate Bystander Neutrophils' Metabolism and Effector Functions When Challenged with Mycobacterium tuberculosis.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2898, doi. 10.3390/ijms25052898
By:
- Murphy, Dearbhla M.;
- Walsh, Anastasija;
- Stein, Laura;
- Petrasca, Andreea;
- Cox, Donal J.;
- Brown, Kevin;
- Duffin, Emily;
- Jameson, Gráinne;
- Connolly, Sarah A.;
- O'Connell, Fiona;
- O'Sullivan, Jacintha;
- Basdeo, Sharee A.;
- Keane, Joseph;
- Phelan, James J.
Publication type:
Article
Estimating influenza incidence using search query deceptiveness and generalized ridge regression.
Published in:
PLoS Computational Biology, 2019, v. 15, n. 10, p. 1, doi. 10.1371/journal.pcbi.1007165
By:
- Priedhorsky, Reid;
- Daughton, Ashlynn R.;
- Barnard, Martha;
- O’Connell, Fiona;
- Osthus, Dave
Publication type:
Article
Real-time ex vivo monitoring of NK cell migration toward obesity-associated oesophageal adenocarcinoma following modulation of CX3CR1.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-54390-5
By:
- Mylod, Eimear;
- O'Connell, Fiona;
- Donlon, Noel E.;
- Davern, Maria;
- Marion, Caroline;
- Butler, Christine;
- Reynolds, John V.;
- Lysaght, Joanne;
- Conroy, Melissa J.
Publication type:
Article

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