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The insulinotropic mechanism of the novel hypoglycaemic agent JTT-608: direct enhancement of Ca<sup>2+</sup> efficacy and increase of Ca<sup>2+</sup> influx by phosphodiesterase inhibition.
Published in:
British Journal of Pharmacology, 2000, v. 129, n. 5, p. 901, doi. 10.1038/sj.bjp.0703133
By:
- Mukai, Eri;
- Ishida, Hitoshi;
- Fujimoto, Shimpei;
- Kajikawa, Mariko;
- Okamoto, Yoshimasa;
- Fujita, Jun;
- Hamamoto, Yoshiyuki;
- Tsuura, Yoshiyuki;
- Yamada, Yuichiro;
- Furukawa, Noboru;
- Ohta, Takeshi;
- Seino, Yutaka
Publication type:
Article
JTT-608 restores impaired early insulin secretion in diabetic Goto-Kakizaki rats.
Published in:
British Journal of Pharmacology, 1999, v. 126, n. 7, p. 1674, doi. 10.1038/sj.bjp.0702481
By:
- Ohta, Takeshi;
- Furukawa, Noboru;
- Komuro, Goro;
- Yonemori, Fumihiko;
- Wakitani, Korekiyo
Publication type:
Article
Updates of incretin‐related drugs for the treatment of type 2 diabetes.
Published in:
Journal of Diabetes Investigation, 2023, v. 14, n. 2, p. 189, doi. 10.1111/jdi.13945
By:
- Araki, Hirotaka;
- Matsumura, Takeshi;
- Furukawa, Noboru;
- Araki, Eiichi
Publication type:
Article
Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes.
Published in:
Journal of Diabetes Investigation, 2019, v. 10, n. 2, p. 521, doi. 10.1111/jdi.12891
By:
- Kondo, Tatsuya;
- Miyakawa, Nobukazu;
- Motoshima, Hiroyuki;
- Hanatani, Satoko;
- Ishii, Norio;
- Igata, Motoyuki;
- Yoshinaga, Kayo;
- Kukidome, Daisuke;
- Senokuchi, Takafumi;
- Kawashima, Junji;
- Furukawa, Noboru;
- Matsumura, Takeshi;
- Araki, Eiichi
Publication type:
Article
Impacts of tight multifactorial intervention in patients with type 2 diabetes: Implications from the Japan Diabetes Outcome Intervention Trial 3.
Published in:
Journal of Diabetes Investigation, 2018, v. 9, n. 5, p. 1022, doi. 10.1111/jdi.12872
By:
- Araki, Eiichi;
- Senokuchi, Takafumi;
- Furukawa, Noboru
Publication type:
Article
Low glucose induces mitochondrial reactive oxygen species via fatty acid oxidation in bovine aortic endothelial cells.
Published in:
Journal of Diabetes Investigation, 2017, v. 8, n. 6, p. 750, doi. 10.1111/jdi.12678
By:
- Kajihara, Nobuhiro;
- Kukidome, Daisuke;
- Sada, Kiminori;
- Motoshima, Hiroyuki;
- Furukawa, Noboru;
- Matsumura, Takeshi;
- Nishikawa, Takeshi;
- Araki, Eiichi
Publication type:
Article
A 1-year, prospective, observational study of Japanese outpatients with type 1 and type 2 diabetes switching from insulin glargine or detemir to insulin degludec in basal-bolus insulin therapy (Kumamoto Insulin Degludec Observational study).
Published in:
Journal of Diabetes Investigation, 2016, v. 7, n. 5, p. 703, doi. 10.1111/jdi.12496
By:
- Shimoda, Seiya;
- Sato, Miki;
- Sekigami, Taiji;
- Motoshima, Hiroyuki;
- Yoshimura, Ryohei;
- Fukuda, Kazuki;
- Matsuo, Yasuto;
- Noda, Hideyuki;
- Okubo, Mina;
- Ichimori, Shinji;
- Fujisawa, Kazuo;
- Fukunaga, Makiko;
- Araki, Eiichi;
- Nishikawa, Takeshi;
- Furukawa, Noboru;
- Matsumura, Takeshi;
- Kondo, Tatsuya;
- Kawashima, Junji;
- Senokuchi, Takafumi;
- Igata, Motoyuki
Publication type:
Article
Comparison of the efficacy of sitagliptin and glimepiride dose-up in Japanese patients with type 2 diabetes poorly controlled by sitagliptin and glimepiride in combination.
Published in:
Journal of Diabetes Investigation, 2014, v. 5, n. 3, p. 320, doi. 10.1111/jdi.12151
By:
- Shimoda, Seiya;
- Iwashita, Shinsuke;
- Sekigami, Taiji;
- Furukawa, Noboru;
- Matsuo, Yasuto;
- Ichimori, Shinji;
- Goto, Rieko;
- Maeda, Takako;
- Watanabe, Eiichiro;
- Kondo, Tatsuya;
- Matsumura, Takeshi;
- Motoshima, Hiroyuki;
- Nishida, Kenro;
- Araki, Eiichi
Publication type:
Article
Depth and Evolution of a Silicic Magma Chamber: Melting Experiments on a Low-K Rhyolite from Usu Volcano, Japan.
Published in:
Journal of Petrology, 2010, v. 51, n. 6, p. 1333, doi. 10.1093/petrology/egq021
By:
- TOMIYA, AKIHIKO;
- TAKAHASHI, EIICHI;
- FURUKAWA, NOBORU;
- SUZUKI, TOSHIHIRO
Publication type:
Article
The Diamond STING server.
Published in:
Nucleic Acids Research, 2005, v. 33, n. suppl 2, p. w29, doi. 10.1093/nar/gki397
By:
- Neshich, Goran;
- Borro, Luiz C.;
- Higa, Roberto H.;
- Kuser, Paula R.;
- Yamagishi, Michel E. B.;
- Franco, Eduardo H.;
- Krauchenco, Joao N.;
- Fileto, Renato;
- Ribeiro, André A.;
- Bezerra, George B. P.;
- Velludo, Thiago M.;
- Jimenez, Tomás S.;
- Furukawa, Noboru;
- Teshima, Hirofumi;
- Kitajima, Koji;
- Bava, Abdulla;
- Sarai, Akinori;
- Togawa, Roberto C.;
- Mancini, Adauto L.
Publication type:
Article
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.
Published in:
Nature, 2004, v. 428, n. 6982, p. 569, doi. 10.1038/nature02440
By:
- Minokoshi, Yasuhiko;
- Aiquier, Thierry;
- Furukawa, Noboru;
- Kim, Young-Bum;
- Lee, Anna;
- Xue, Bingzhong;
- Mu, James;
- Foufelle, Fabienne;
- Ferré, Pascal;
- Birnbaum, Morris J.;
- Stuck, Bettina J.;
- Kahn, Barbara B.
Publication type:
Article
In situ hydraulic tests in the active fault survey tunnel, Kamioka Mine, excavated through the active Mozumi-Sukenobu Fault zone and their hydrogeological significance.
Published in:
Island Arc, 2006, v. 15, n. 4, p. 537, doi. 10.1111/j.1440-1738.2006.00548.x
By:
- Nohara, Tsuyoshi;
- Tanaka, Hidemi;
- Watanabe, Kunio;
- Furukawa, Noboru;
- Takami, Akira
Publication type:
Article
Ezetimibe improves glucose metabolism by ameliorating hepatic function in Japanese patients with type 2 diabetes.
Published in:
Journal of Diabetes Investigation, 2012, v. 3, n. 2, p. 179, doi. 10.1111/j.2040-1124.2011.00147.x
By:
- Ichimori, Shinji;
- Shimoda, Seiya;
- Goto, Rieko;
- Matsuo, Yasuto;
- Maeda, Takako;
- Furukawa, Noboru;
- Kawashima, Junji;
- Kodama, Shoko;
- Sekigami, Taiji;
- Isami, Satoshi;
- Nishida, Kenro;
- Araki, Eiichi
Publication type:
Article
Predictors of coronary heart disease in Japanese patients with type 2 diabetes: Screening for coronary artery stenosis using multidetector computed tomography.
Published in:
Journal of Diabetes Investigation, 2010, v. 1, n. 1/2, p. 50, doi. 10.1111/j.2040-1124.2009.00003.x
By:
- Nishioka, Hiroko;
- Furukawa, Noboru;
- Shimoda, Seiya;
- Nishida, Kenro;
- Nakaura, Takeshi;
- Maeda, Takako;
- Goto, Rieko;
- Miyamura, Nobuhiro;
- Awai, Kazuo;
- Yamashita, Yasuyuki;
- Araki, Eiichi
Publication type:
Article
Downslope variation in hemipelagic sedimentation in an active margin basin: An example from the lower Pleistocene Kiwada and Takamizo formations on the Boso Peninsula, Japan.
Published in:
Sedimentology, 2023, v. 70, n. 3, p. 705, doi. 10.1111/sed.13055
By:
- Kurosawa, Shiho;
- Furota, Satoshi;
- Mitsui, Mayu;
- Sawada, Ken;
- Seike, Koji;
- Furukawa, Noboru;
- Ito, Makoto
Publication type:
Article
Rottlerin, a PKC-delta Inhibitor, Strongly Suppresses Cell Cycle Progression in Vascular Smooth Muscle Cell Through AMPK Activation.
Published in:
Diabetes, 2007, v. 56, p. A599
By:
- Motoshima, Hiroyuki;
- Kojima, Kanou;
- Igata, Motoyuki;
- Tsutsumi, Atsuyuki;
- Kondo, Tatsuya;
- Matsumura, Takeshi;
- Furukawa, Noboru;
- Tsuruzoe, Kaku;
- Nishikawa, Takeshi;
- Araki, Eiichi
Publication type:
Article
Irs-1 Transgenic Mice Showed Increased Epididymal Fat Mass and Displayed Insulin Resistance In Vivo.
Published in:
Diabetes, 2007, v. 56, p. A346
By:
- Murata, Yusuke;
- Tsuruzoe, Kaku;
- Toyonaga, Tetushi;
- Furukawa, Noboru;
- Kondo, Tatsuya;
- Motoshima, Hiroyuki;
- Igata, Motoyuki;
- Taketa, Kayo;
- Sasaki, Kazunari;
- Araki, Eiichi
Publication type:
Article
Increased insulin sensitivity and hypoinsulinemia in APS knockout mice.
Published in:
2003
By:
- Minami, Asako;
- Iseki, Masanori;
- Kishi, Kazuhiro;
- Wang, Miao;
- Ogura, Makoto;
- Furukawa, Noboru;
- Hayashi, Sanae;
- Yamada, Mizuki;
- Obata, Toshiyuki;
- Takeshita, Yukari;
- Nakaya, Yutaka;
- Bando, Yoshimi;
- Izumi, Keisuke;
- Moodie, Shonna A.;
- Kajiura, Fumiko;
- Matsumoto, Mitsuru;
- Takatsu, Kiyoshi;
- Takaki, Satoshi;
- Ebina, Yousuke
Publication type:
journal article
Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas.
Published in:
1998
By:
- Tsuruzoe, Kaku;
- Araki, Eiichi;
- Furukawa, Noboru;
- Shirotani, Tetsuya;
- Matsumoto, Kazuya;
- Kaneko, Kengo;
- Motoshima, Hiroyuki;
- Yoshizato, Kazuaki;
- Shirakami, Atsuhisa;
- Kishikawa, Hideki;
- Miyazaki, Jun-ichi;
- Shichiri, Motoaki;
- Tsuruzoe, K;
- Araki, E;
- Furukawa, N;
- Shirotani, T;
- Matsumoto, K;
- Kaneko, K;
- Motoshima, H;
- Yoshizato, K
Publication type:
journal article
Impact of natural IRS-1 mutations on insulin signals: mutations of IRS-1 in the PTB domain and near SH2 protein binding sites result in impaired function at different steps of IRS-1 signaling.
Published in:
1997
By:
- Yoshimura, Ryohei;
- Araki, Eiichi;
- Ura, Sachiko;
- Todaka, Mikio;
- Tsuruzoe, Kaku;
- Furukawa, Noboru;
- Motoshima, Hiroyuki;
- Yoshizato, Kazuaki;
- Kaneko, Kengo;
- Matsuda, Kohji;
- Kishikawa, Hideki;
- Shichiri, Motoaki;
- Yoshimura, R;
- Araki, E;
- Ura, S;
- Todaka, M;
- Tsuruzoe, K;
- Furukawa, N;
- Motoshima, H;
- Yoshizato, K
Publication type:
journal article
Cell-specific regulation of IRS-1 gene expression: role of E box and C/EBP binding site in HepG2 cells and CHO cells.
Published in:
1997
By:
- Matsuda, Kohji;
- Araki, Eiichi;
- Yoshimura, Ryohei;
- Tsuruzoe, Kaku;
- Furukawa, Noboru;
- Kaneko, Kengo;
- Motoshima, Hiroyuki;
- Yoshizato, Kazuaki;
- Kishikawa, Hideki;
- Shichiri, Motoaki;
- Matsuda, K;
- Araki, E;
- Yoshimura, R;
- Tsuruzoe, K;
- Furukawa, N;
- Kaneko, K;
- Motoshima, H;
- Yoshizato, K;
- Kishikawa, H;
- Shichiri, M
Publication type:
journal article
Insulin requirement profiles in Japanese hospitalized subjects with type 2 diabetes treated with basal-bolus insulin therapy.
Published in:
Endocrine Journal, 2015, v. 62, n. 2, p. 209, doi. 10.1507/endocrj.ej14-0487
By:
- Seiya Shimoda;
- Mina Okubo;
- Kotaro Koga;
- Taiji Sekigami;
- Junji Kawashima;
- Daisuke Kukidome;
- Motoyuki Igata;
- Norio Ishii;
- Akiko Shimakawa;
- Takeshi Matsumura;
- Hiroyuki Motoshima;
- Noboru Furukawa;
- Kenro Nishida;
- Eiichi Araki
Publication type:
Article
Efficacy and safety of sitagliptin as add-on therapy on glycemic control and blood glucose fluctuation in Japanese type 2 diabetes subjects ongoing with multiple daily insulin injections therapy.
Published in:
Endocrine Journal, 2013, v. 60, n. 10, p. 1207, doi. 10.1507/endocrj.ej13-0198
By:
- Seiya Shimoda;
- Shinsuke Iwashita;
- Shinji Ichimori;
- Yasuto Matsuo;
- Rieko Goto;
- Takako Maeda;
- Tomoko Matsuo;
- Taiji Sekigami;
- Junji Kawashima;
- Tatsuya Kondo;
- Takeshi Matsumura;
- Hiroyuki Motoshima;
- Noboru Furukawa;
- Kenro Nishida;
- Eiichi Araki
Publication type:
Article
Are saving appearance responses typical communication patterns in Alzheimer's disease?
Published in:
PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197468
By:
- Matsushita, Masateru;
- Yatabe, Yusuke;
- Koyama, Asuka;
- Katsuya, Akiko;
- Ijichi, Daisuke;
- Miyagawa, Yusuke;
- Ikezaki, Hiroto;
- Furukawa, Noboru;
- Ikeda, Manabu;
- Hashimoto, Mamoru
Publication type:
Article
Why do people with dementia pretend to know the correct answer? A qualitative study on the behaviour of toritsukuroi to keep up appearances.
Published in:
Psychogeriatrics, 2017, v. 17, n. 6, p. 377, doi. 10.1111/psyg.12253
By:
- Matsushita, Masateru;
- Yatabe, Yusuke;
- Koyama, Asuka;
- Ueno, Yukiko;
- Ijichi, Daisuke;
- Ikezaki, Hiroto;
- Hashimoto, Mamoru;
- Furukawa, Noboru;
- Ikeda, Manabu
Publication type:
Article
High-temperature structural change and microtexture formation of sillimanite and its phase relation with mullite.
Published in:
American Mineralogist, 2019, v. 104, n. 7, p. 1051, doi. 10.2138/am-2019-6732
By:
- Igami, Yohei;
- Ohi, Shugo;
- Kogiso, Tetsu;
- Furukawa, Noboru;
- Miyake, Akira
Publication type:
Article
Identification of microRNA that represses IRS-1 expression in liver.
Published in:
PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191553
By:
- Ono, Kaoru;
- Igata, Motoyuki;
- Kondo, Tatsuya;
- Kitano, Sayaka;
- Takaki, Yuki;
- Hanatani, Satoko;
- Sakaguchi, Masaji;
- Goto, Rieko;
- Senokuchi, Takafumi;
- Kawashima, Junji;
- Furukawa, Noboru;
- Motoshima, Hiroyuki;
- Araki, Eiichi
Publication type:
Article
Hyperthermia with mild electrical stimulation protects pancreatic β-cells from cell stresses and apoptosis.
Published in:
2012
By:
- Kondo T;
- Sasaki K;
- Matsuyama R;
- Morino-Koga S;
- Adachi H;
- Suico MA;
- Kawashima J;
- Motoshima H;
- Furukawa N;
- Kai H;
- Araki E;
- Kondo, Tatsuya;
- Sasaki, Kazunari;
- Matsuyama, Rina;
- Morino-Koga, Saori;
- Adachi, Hironori;
- Suico, Mary Ann;
- Kawashima, Junji;
- Motoshima, Hiroyuki;
- Furukawa, Noboru
Publication type:
journal article
Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis.
Published in:
Diabetes, 2012, v. 61, n. 4, p. 838, doi. 10.2337/db11-1098
By:
- Kondo, Tatsuya;
- Sasaki, Kazunari;
- Matsuyama, Rina;
- Morino-Koga, Saori;
- Adachi, Hironori;
- Suico, Mary Ann;
- Kawashima, Junji;
- Motoshima, Hiroyuki;
- Furukawa, Noboru;
- Kai, Hirofumi;
- Araki, Eiichi
Publication type:
Article

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