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Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts.
Published in:
Journal of Pathology, 2024, v. 263, n. 3, p. 360, doi. 10.1002/path.6289
By:
- Hutten, Stefan J;
- Messal, Hendrik A;
- Lips, Esther H;
- Sheinman, Michael;
- Ciwinska, Marta;
- Braams, Esmee;
- van der Borden, Carolien;
- Kristel, Petra;
- Stoffers, Saskia;
- Wessels, Lodewyk FA;
- Wesseling, Jelle;
- Jonkers, Jos;
- van Rheenen, Jacco;
- Schmidt, Marjanka;
- Bhattacharjee, Proteeti;
- Thompson, Alastair;
- Nik‐Zainal, Serena;
- Davies, Helen;
- Sawyer, Elinor J;
- Futreal, Andrew
Publication type:
Article
Uncovering the genomic heterogeneity of multifocal breast cancer.
Published in:
Journal of Pathology, 2015, v. 236, n. 4, p. 457, doi. 10.1002/path.4540
By:
- Desmedt, Christine;
- Fumagalli, Debora;
- Pietri, Elisabetta;
- Zoppoli, Gabriele;
- Brown, David;
- Nik‐Zainal, Serena;
- Gundem, Gunes;
- Rothé, Françoise;
- Majjaj, Samira;
- Garuti, Anna;
- Carminati, Enrico;
- Loi, Sherene;
- Van Brussel, Thomas;
- Boeckx, Bram;
- Maetens, Marion;
- Mudie, Laura;
- Vincent, Delphine;
- Kheddoumi, Naima;
- Serra, Luigi;
- Massa, Ilaria
Publication type:
Article
A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-21706-2
By:
- Inglebert, Marine;
- Dettwiler, Martina;
- Hahn, Kerstin;
- Letko, Anna;
- Drogemuller, Cord;
- Doench, John;
- Brown, Adam;
- Memari, Yasin;
- Davies, Helen R.;
- Degasperi, Andrea;
- Nik-Zainal, Serena;
- Rottenberg, Sven
Publication type:
Article
Short inverted repeats contribute to localized mutability in human somatic cells.
Published in:
Nucleic Acids Research, 2017, v. 45, n. 19, p. 11213, doi. 10.1093/nar/gkx731
By:
- Xueqing Zou;
- Morganella, Sandro;
- Glodzik, Dominik;
- Davies, Helen;
- Yilin Li;
- Stratton, Michael R.;
- Nik-Zainal, Serena
Publication type:
Article
Exclusion of the GNAS locus in PHP-Ib patients with broad GNAS methylation changes: Evidence for an autosomal recessive form of PHP-Ib?
Published in:
Journal of Bone & Mineral Research, 2011, v. 26, n. 8, p. 1854, doi. 10.1002/jbmr.408
By:
- Fernández-Rebollo, Eduardo;
- Pérez de Nanclares, Guiomar;
- Lecumberri, Beatriz;
- Turan, Serap;
- Anda, Emma;
- Pérez-Nanclares, Gustavo;
- Feig, Denice;
- Nik-Zainal, Serena;
- Bastepe, Murat;
- Jüppner, Harald
Publication type:
Article
Subclonal diversification of primary breast cancer revealed by multiregion sequencing.
Published in:
Nature Medicine, 2015, v. 21, n. 7, p. 751, doi. 10.1038/nm.3886
By:
- Yates, Lucy R;
- Gerstung, Moritz;
- Knappskog, Stian;
- Desmedt, Christine;
- Gundem, Gunes;
- Van Loo, Peter;
- Aas, Turid;
- Alexandrov, Ludmil B;
- Larsimont, Denis;
- Davies, Helen;
- Li, Yilong;
- Ju, Young Seok;
- Ramakrishna, Manasa;
- Haugland, Hans Kristian;
- Lilleng, Peer Kaare;
- Nik-Zainal, Serena;
- McLaren, Stuart;
- Butler, Adam;
- Martin, Sancha;
- Glodzik, Dominic
Publication type:
Article
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer.
Published in:
Nature Genetics, 2014, v. 46, n. 5, p. 487, doi. 10.1038/ng.2955
By:
- Nik-Zainal, Serena;
- Wedge, David C;
- Alexandrov, Ludmil B;
- Petljak, Mia;
- Butler, Adam P;
- Bolli, Niccolo;
- Davies, Helen R;
- Knappskog, Stian;
- Martin, Sancha;
- Papaemmanuil, Elli;
- Ramakrishna, Manasa;
- Shlien, Adam;
- Simonic, Ingrid;
- Xue, Yali;
- Tyler-Smith, Chris;
- Campbell, Peter J;
- Stratton, Michael R
Publication type:
Article
Corrigendum: Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.
Published in:
Nature Genetics, 2014, v. 46, n. 3, p. 316, doi. 10.1038/ng0314-316
By:
- Behjati, Sam;
- Tarpey, Patrick S;
- Presneau, Nadège;
- Scheipl, Susanne;
- Pillay, Nischalan;
- Van Loo, Peter;
- Wedge, David C;
- Cooke, Susanna L;
- Gundem, Gunes;
- Davies, Helen;
- Nik-Zainal, Serena;
- Martin, Sancha;
- McLaren, Stuart;
- Goodie, Victoria;
- Robinson, Ben;
- Butler, Adam;
- Teague, Jon W;
- Halai, Dina;
- Khatri, Bhavisha;
- Myklebost, Ola
Publication type:
Article
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
Published in:
Nature Genetics, 2014, v. 46, n. 2, p. 116, doi. 10.1038/ng.2874
By:
- Papaemmanuil, Elli;
- Rapado, Inmaculada;
- Li, Yilong;
- Potter, Nicola E;
- Wedge, David C;
- Tubio, Jose;
- Alexandrov, Ludmil B;
- Van Loo, Peter;
- Cooke, Susanna L;
- Marshall, John;
- Martincorena, Inigo;
- Hinton, Jonathan;
- Gundem, Gunes;
- van Delft, Frederik W;
- Nik-Zainal, Serena;
- Jones, David R;
- Ramakrishna, Manasa;
- Titley, Ian;
- Stebbings, Lucy;
- Leroy, Catherine
Publication type:
Article
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.
Published in:
Nature Genetics, 2013, v. 45, n. 12, p. 1479, doi. 10.1038/ng.2814
By:
- Behjati, Sam;
- Tarpey, Patrick S;
- Presneau, Nadège;
- Scheipl, Susanne;
- Pillay, Nischalan;
- Van Loo, Peter;
- Wedge, David C;
- Cooke, Susanna L;
- Gundem, Gunes;
- Davies, Helen;
- Nik-Zainal, Serena;
- Martin, Sancha;
- McLaren, Stuart;
- Goodie, Victoria;
- Robinson, Ben;
- Butler, Adam;
- Teague, Jon W;
- Halai, Dina;
- Khatri, Bhavisha;
- Myklebost, Ola
Publication type:
Article
Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.
Published in:
Nature Genetics, 2013, v. 45, n. 8, p. 923, doi. 10.1038/ng.2668
By:
- Tarpey, Patrick S;
- Behjati, Sam;
- Cooke, Susanna L;
- Van Loo, Peter;
- Wedge, David C;
- Pillay, Nischalan;
- Marshall, John;
- O'Meara, Sarah;
- Davies, Helen;
- Nik-Zainal, Serena;
- Beare, David;
- Butler, Adam;
- Gamble, John;
- Hardy, Claire;
- Hinton, Jonathon;
- Jia, Ming Ming;
- Jayakumar, Alagu;
- Jones, David;
- Latimer, Calli;
- Maddison, Mark
Publication type:
Article
Familial Adrenocortical Carcinoma in Association With Lynch Syndrome.
Published in:
2016
By:
- Challis, Benjamin G;
- Kandasamy, Narayanan;
- Powlson, Andrew S;
- Koulouri, Olympia;
- Annamalai, Anand Kumar;
- Happerfield, Lisa;
- Marker, Alison J;
- Arends, Mark J;
- Nik-Zainal, Serena;
- Gurnell, Mark
Publication type:
journal article
Mechanisms underlying mutational signatures in human cancers.
Published in:
Nature Reviews Genetics, 2014, v. 15, n. 9, p. 585, doi. 10.1038/nrg3729
By:
- Helleday, Thomas;
- Eshtad, Saeed;
- Nik-Zainal, Serena
Publication type:
Article
P14 Whole-genome sequencing of malignant cylindroma in CYLD cutaneous syndrome reveals a clinically targetable somatic driver mutation.
Published in:
British Journal of Dermatology, 2023, v. 189, n. 1, p. e19, doi. 10.1093/bjd/ljad174.035
By:
- Fostier, William;
- Koh, Ching Chiek;
- Husain, Akhtar;
- Namini, Shirin;
- Nik-Zainal, Serena;
- Rajan, Neil
Publication type:
Article
Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12746-w
By:
- Davies, Helen R.;
- Hodgson, Kirsty;
- Schwalbe, Edward;
- Coxhead, Jonathan;
- Sinclair, Naomi;
- Zou, Xueqing;
- Cockell, Simon;
- Husain, Akhtar;
- Nik-Zainal, Serena;
- Rajan, Neil
Publication type:
Article
Author Correction: A practical guide for mutational signature analysis in hematological malignancies.
Published in:
2019
By:
- Maura, Francesco;
- Degasperi, Andrea;
- Nadeu, Ferran;
- Leongamornlert, Daniel;
- Davies, Helen;
- Moore, Luiza;
- Royo, Romina;
- Ziccheddu, Bachisio;
- Puente, Xose S.;
- Avet-Loiseau, Herve;
- Campbell, Peter J.;
- Nik-Zainal, Serena;
- Campo, Elias;
- Munshi, Nikhil;
- Bolli, Niccolò
Publication type:
Correction Notice
A practical guide for mutational signature analysis in hematological malignancies.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11037-8
By:
- Maura, Francesco;
- Degasperi, Andrea;
- Nadeu, Ferran;
- Leongamornlert, Daniel;
- Davies, Helen;
- Moore, Luiza;
- Royo, Romina;
- Ziccheddu, Bachisio;
- Puente, Xose S.;
- Avet-Loiseau, Herve;
- Cambell, Peter J.;
- Nik-Zainal, Serena;
- Campo, Elias;
- Munshi, Nikhil;
- Bolli, Niccolò
Publication type:
Article
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09828-0
By:
- Brinkman, Arie B.;
- Nik-Zainal, Serena;
- Simmer, Femke;
- Rodríguez-González, F. Germán;
- Smid, Marcel;
- Alexandrov, Ludmil B.;
- Butler, Adam;
- Martin, Sancha;
- Davies, Helen;
- Glodzik, Dominik;
- Zou, Xueqing;
- Ramakrishna, Manasa;
- Staaf, Johan;
- Ringnér, Markus;
- Sieuwerts, Anieta;
- Ferrari, Anthony;
- Morganella, Sandro;
- Fleischer, Thomas;
- Kristensen, Vessela;
- Gut, Marta
Publication type:
Article
Whole-Genome Sequencing of Retinoblastoma Reveals the Diversity of Rearrangements Disrupting RB1 and Uncovers a Treatment-Related Mutational Signature.
Published in:
Cancers, 2021, v. 13, n. 4, p. 754, doi. 10.3390/cancers13040754
By:
- Davies, Helen R.;
- Broad, Kevin D.;
- Onadim, Zerrin;
- Price, Elizabeth A.;
- Zou, Xueqing;
- Sheriff, Ibrahim;
- Karaa, Esin Kotiloğlu;
- Scheimberg, Irene;
- Reddy, M. Ashwin;
- Sagoo, Mandeep S.;
- Ohnuma, Shin-ichi;
- Nik-Zainal, Serena;
- MacPherson, David
Publication type:
Article
Two Secreted Proteoglycans, Activators of Urothelial Cell–Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression.
Published in:
Cancers, 2020, v. 12, n. 11, p. 3362, doi. 10.3390/cancers12113362
By:
- Papadaki, Vasiliki;
- Asada, Ken;
- Watson, Julie K.;
- Tamura, Toshiya;
- Leung, Alex;
- Hopkins, Jack;
- Dellett, Margaret;
- Sasai, Noriaki;
- Davaapil, Hongorzul;
- Nik-Zainal, Serena;
- Longbottom, Rebecca;
- Nakakido, Makoto;
- Torii, Ryo;
- Veerakumarasivam, Abhi;
- Kaneko, Syuzo;
- Sagoo, Mandeep S.;
- Murphy, Gillian;
- Mitani, Akihisa;
- Tsumoto, Kohei;
- Kelly, John D.
Publication type:
Article
The patterns and dynamics of genomic instability in metastatic pancreatic cancer.
Published in:
Nature, 2010, v. 467, n. 7319, p. 1109, doi. 10.1038/nature09460
By:
- Campbell, Peter J.;
- Yachida, Shinichi;
- Mudie, Laura J.;
- Stephens, Philip J.;
- Pleasance, Erin D.;
- Stebbings, Lucy A.;
- Morsberger, Laura A.;
- Latimer, Calli;
- McLaren, Stuart;
- Lin, Meng-Lay;
- McBride, David J.;
- Varela, Ignacio;
- Nik-Zainal, Serena A.;
- Leroy, Catherine;
- Jia, Mingming;
- Menzies, Andrew;
- Butler, Adam P.;
- Teague, Jon W.;
- Griffin, Constance A.;
- Burton, John
Publication type:
Article
Insights into cancer biology through next-generation sequencing.
Published in:
2014
By:
- Nik-Zainal, Serena
Publication type:
Journal Article
Insights into cancer biology through next-generation sequencing.
Published in:
Clinical Medicine, 2014, v. 14, p. s71, doi. 10.7861/clinmedicine.14-6-s71
By:
- Nik-Zainal, Serena
Publication type:
Article
Application of deep learning on mammographies to discriminate between low and high-risk DCIS for patient participation in active surveillance trials.
Published in:
Cancer Imaging, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s40644-024-00691-x
By:
- Alaeikhanehshir, Sena;
- Voets, Madelon M.;
- van Duijnhoven, Frederieke H.;
- lips, Esther H.;
- Groen, Emma J.;
- van Oirsouw, Marja C. J.;
- Hwang, Shelley E.;
- Lo, Joseph Y.;
- Wesseling, Jelle;
- Mann, Ritse M.;
- Teuwen, Jonas;
- Thompson, Alastair;
- Nik-Zainal, Serena;
- Sawyer, Elinor J.;
- Davies, Helen;
- Futreal, Andrew;
- Navin, Nicholas;
- Hwang, E. Shelley;
- Jonkers, Jos;
- Rheenen, Jacco van
Publication type:
Article
Application of deep learning on mammographies to discriminate between low and high-risk DCIS for patient participation in active surveillance trials.
Published in:
Cancer Imaging, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s40644-024-00691-x
By:
- Alaeikhanehshir, Sena;
- Voets, Madelon M.;
- van Duijnhoven, Frederieke H.;
- lips, Esther H.;
- Groen, Emma J.;
- van Oirsouw, Marja C. J.;
- Hwang, Shelley E.;
- Lo, Joseph Y.;
- Wesseling, Jelle;
- Mann, Ritse M.;
- Teuwen, Jonas;
- Thompson, Alastair;
- Nik-Zainal, Serena;
- Sawyer, Elinor J.;
- Davies, Helen;
- Futreal, Andrew;
- Navin, Nicholas;
- Hwang, E. Shelley;
- Jonkers, Jos;
- Rheenen, Jacco van
Publication type:
Article
APOBEC3A/B deletion polymorphism and cancer risk.
Published in:
Carcinogenesis, 2018, v. 39, n. 2, p. 118, doi. 10.1093/carcin/bgx131
By:
- Gansmo, Liv B.;
- Romundstad, Paal;
- Hveem, Kristian;
- Vatten, Lars;
- Nik-Zainal, Serena;
- Lønning, Per Eystein;
- Knappskog, Stian
Publication type:
Article
Mutational signatures of ionizing radiation in second malignancies.
Published in:
Nature Communications, 2016, v. 7, n. 9, p. 12605, doi. 10.1038/ncomms12605
By:
- Behjati, Sam;
- Gundem, Gunes;
- Wedge, David C.;
- Roberts, Nicola D.;
- Tarpey, Patrick S.;
- Cooke, Susanna L.;
- Van Loo, Peter;
- Alexandrov, Ludmil B.;
- Ramakrishna, Manasa;
- Davies, Helen;
- Nik-Zainal, Serena;
- Hardy, Claire;
- Latimer, Calli;
- Raine, Keiran M.;
- Stebbings, Lucy;
- Menzies, Andy;
- Jones, David;
- Shepherd, Rebecca;
- Butler, Adam P.;
- Teague, Jon W.
Publication type:
Article
Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.
Published in:
Nature Communications, 2016, v. 7, n. 9, p. 12910, doi. 10.1038/ncomms12910
By:
- Smid, Marcel;
- Rodríguez-González, F. Germán;
- Sieuwerts, Anieta M.;
- Salgado, Roberto;
- Prager-Van der Smissen, Wendy J. C.;
- Vlugt-Daane, Michelle van der;
- van Galen, Anne;
- Nik-Zainal, Serena;
- Staaf, Johan;
- Brinkman, Arie B.;
- van de Vijver, Marc J.;
- Richardson, Andrea L.;
- Fatima, Aquila;
- Berentsen, Kim;
- Butler, Adam;
- Martin, Sancha;
- Davies, Helen R.;
- Debets, Reno;
- Gelder, Marion E. Meijer-Van;
- van Deurzen, Carolien H. M.
Publication type:
Article
A mutational signature in gastric cancer suggests therapeutic strategies.
Published in:
Nature Communications, 2015, v. 6, n. 10, p. 8683, doi. 10.1038/ncomms9683
By:
- Alexandrov, Ludmil B.;
- Nik-Zainal, Serena;
- Siu, Hoi Cheong;
- Leung, Suet Yi;
- Stratton, Michael R
Publication type:
Article
Processed pseudogenes acquired somatically during cancer development.
Published in:
Nature Communications, 2014, v. 5, n. 4, p. 3644, doi. 10.1038/ncomms4644
By:
- Cooke, Susanna L.;
- Shlien, Adam;
- Marshall, John;
- Pipinikas, Christodoulos P.;
- Martincorena, Inigo;
- Tubio, Jose M.C.;
- Li, Yilong;
- Menzies, Andrew;
- Mudie, Laura;
- Ramakrishna, Manasa;
- Yates, Lucy;
- Davies, Helen;
- Bolli, Niccolo;
- Bignell, Graham R.;
- Tarpey, Patrick S.;
- Behjati, Sam;
- Nik-Zainal, Serena;
- Papaemmanuil, Elli;
- Teixeira, Vitor H.;
- Raine, Keiran
Publication type:
Article
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.
Published in:
Nature Communications, 2014, v. 5, n. 1, p. 2997, doi. 10.1038/ncomms3997
By:
- Bolli, Niccolo;
- Avet-Loiseau, Hervé;
- Wedge, David C.;
- Van Loo, Peter;
- Alexandrov, Ludmil B.;
- Martincorena, Inigo;
- Dawson, Kevin J.;
- Iorio, Francesco;
- Nik-Zainal, Serena;
- Bignell, Graham R.;
- Hinton, Jonathan W.;
- Li, Yilong;
- Tubio, Jose M.C.;
- McLaren, Stuart;
- O' Meara, Sarah;
- Butler, Adam P.;
- Teague, Jon W.;
- Mudie, Laura;
- Anderson, Elizabeth;
- Rashid, Naim
Publication type:
Article
The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.
Published in:
Genome Biology, 2013, v. 14, n. 10, p. 3, doi. 10.1186/gb-2013-14-10-r113
By:
- Yen, Jennifer;
- White, Richard M.;
- Wedge, David C.;
- Loo, Peter Van;
- Ridder, Jeroen de;
- Capper, Amy;
- Richardson, Jennifer;
- Jones, David;
- Raine, Keiran;
- Watson, Ian R.;
- Chang-Jiun Wu;
- Jiqiu Cheng;
- Martincorena, Iñigo;
- Nik-Zainal, Serena;
- Mudie, Laura;
- Moreau, Yves;
- Marshall, John;
- Ramakrishna, Manasa;
- Tarpey, Patrick;
- Shlien, Adam
Publication type:
Article
Ductal carcinoma in situ: to treat or not to treat, that is the question.
Published in:
2019
By:
- van Seijen, Maartje;
- Lips, Esther H.;
- Thompson, Alastair M.;
- Nik-Zainal, Serena;
- Futreal, Andrew;
- Hwang, E. Shelley;
- Verschuur, Ellen;
- Lane, Joanna;
- Jonkers, Jos;
- Rea, Daniel W.;
- Wesseling, Jelle;
- PRECISION team
Publication type:
journal article
Corrigendum: Signatures of mutational processes in human cancer.
Published in:
Nature, 2013, v. 502, n. 7470, p. 258, doi. 10.1038/nature12666
By:
- Alexandrov, Ludmil B.;
- Nik-Zainal, Serena;
- Wedge, David C.;
- Aparicio, Samuel A. J. R.;
- Behjati, Sam;
- Biankin, Andrew V.;
- Bignell, Graham R.;
- Bolli, Niccolò;
- Borg, Ake;
- Børresen-Dale, Anne-Lise;
- Boyault, Sandrine;
- Burkhardt, Birgit;
- Butler, Adam P.;
- Caldas, Carlos;
- Davies, Helen R.;
- Desmedt, Christine;
- Eils, Roland;
- Eyfjörd, Jórunn Erla;
- Foekens, John A.;
- Greaves, Mel
Publication type:
Article
Signatures of mutational processes in human cancer.
Published in:
Nature, 2013, v. 500, n. 7463, p. 415, doi. 10.1038/nature12477
By:
- Alexandrov, Ludmil B.;
- Nik-Zainal, Serena;
- Wedge, David C.;
- Aparicio, Samuel A. J. R.;
- Behjati, Sam;
- Biankin, Andrew V.;
- Bignell, Graham R.;
- Bolli, Niccolò;
- Borg, Ake;
- Børresen-Dale, Anne-Lise;
- Boyault, Sandrine;
- Burkhardt, Birgit;
- Butler, Adam P.;
- Caldas, Carlos;
- Davies, Helen R.;
- Desmedt, Christine;
- Eils, Roland;
- Eyfjörd, Jórunn Erla;
- Foekens, John A.;
- Greaves, Mel
Publication type:
Article
The landscape of cancer genes and mutational processes in breast cancer.
Published in:
Nature, 2012, v. 486, n. 7403, p. 400, doi. 10.1038/nature11017
By:
- Stephens, Philip J.;
- Tarpey, Patrick S.;
- Davies, Helen;
- Van Loo, Peter;
- Greenman, Chris;
- Wedge, David C.;
- Nik-Zainal, Serena;
- Martin, Sancha;
- Varela, Ignacio;
- Bignell, Graham R.;
- Yates, Lucy R.;
- Papaemmanuil, Elli;
- Beare, David;
- Butler, Adam;
- Cheverton, Angela;
- Gamble, John;
- Hinton, Jonathan;
- Jia, Mingming;
- Jayakumar, Alagu;
- Jones, David
Publication type:
Article
The genome as a record of environmental exposure.
Published in:
Mutagenesis, 2015, v. 30, n. 6, p. 763, doi. 10.1093/mutage/gev073
By:
- Nik-Zainal, Serena;
- Kucab, Jill E.;
- Morganella, Sandro;
- Glodzik, Dominik;
- Alexandrov, Ludmil B.;
- Arlt, Volker M.;
- Weninger, Annette;
- Hollstein, Monica;
- Stratton, Michael R.;
- Phillips, David H.
Publication type:
Article
Validating the concept of mutational signatures with isogenic cell models.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04052-8
By:
- Xueqing Zou;
- Owusu, Michel;
- Harris, Rebecca;
- Jackson, Stephen P.;
- Loizou, Joanna I.;
- Nik-Zainal, Serena
Publication type:
Article
Mutational signatures: experimental design and analytical framework.
Published in:
Genome Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s13059-020-1951-5
By:
- Koh, Gene;
- Zou, Xueqing;
- Nik-Zainal, Serena
Publication type:
Article
Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15901-w
By:
- Georgakopoulos-Soares, Ilias;
- Koh, Gene;
- Momen, Sophie E.;
- Jiricny, Josef;
- Hemberg, Martin;
- Nik-Zainal, Serena
Publication type:
Article
Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15271-3
By:
- Thompson, Oliver;
- von Meyenn, Ferdinand;
- Hewitt, Zoe;
- Alexander, John;
- Wood, Andrew;
- Weightman, Richard;
- Gregory, Sian;
- Krueger, Felix;
- Andrews, Simon;
- Barbaric, Ivana;
- Gokhale, Paul J.;
- Moore, Harry D.;
- Reik, Wolf;
- Milo, Marta;
- Nik-Zainal, Serena;
- Yusa, Kosuke;
- Andrews, Peter W.
Publication type:
Article
From genome integrity to cancer.
Published in:
Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0617-y
By:
- Nik-Zainal, Serena
Publication type:
Article
Non-BRCA1/BRCA2 high-risk familial breast cancers are not associated with a high prevalence of BRCAness.
Published in:
Breast Cancer Research, 2023, v. 25, n. 1, p. 1, doi. 10.1186/s13058-023-01655-y
By:
- Andersen, Lars v. B.;
- Larsen, Martin J.;
- Davies, Helen;
- Degasperi, Andrea;
- Nielsen, Henriette Roed;
- Jensen, Louise A.;
- Kroeldrup, Lone;
- Gerdes, Anne-Marie;
- Lænkholm, Anne-Vibeke;
- Kruse, Torben A.;
- Nik-Zainal, Serena;
- Thomassen, Mads
Publication type:
Article
Mutational History of a Human Cell Lineage from Somatic to Induced Pluripotent Stem Cells.
Published in:
PLoS Genetics, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pgen.1005932
By:
- Rouhani, Foad J.;
- Nik-Zainal, Serena;
- Wuster, Arthur;
- Li, Yilong;
- Conte, Nathalie;
- Koike-Yusa, Hiroko;
- Kumasaka, Natsuhiko;
- Vallier, Ludovic;
- Yusa, Kosuke;
- Bradley, Allan
Publication type:
Article

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