Found: 64
Select item for more details and to access through your institution.
Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged Mice.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death.
- Published in:
- Scientific Reports, 2014, p. 1, doi. 10.1038/srep03631
- By:
- Publication type:
- Article
The Role of DNA Repair in Immunological Diversity: From Molecular Mechanisms to Clinical Ramifications.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.834889
- By:
- Publication type:
- Article
ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer.
- Published in:
- Pharmacogenomics & Personalized Medicine, 2011, v. 4, p. 47, doi. 10.2147/PGPM.S20317
- By:
- Publication type:
- Article
DNA damage drives accelerated bone aging via an NF- κB-dependent mechanism.
- Published in:
- Journal of Bone & Mineral Research, 2013, v. 28, n. 5, p. 1214, doi. 10.1002/jbmr.1851
- By:
- Publication type:
- Article
Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis-like symptoms in NOD mice.
- Published in:
- FASEB Journal, 2019, v. 33, n. 8, p. 9505, doi. 10.1096/fj.201900420R
- By:
- Publication type:
- Article
Role of Cellular Senescence in Type II Diabetes.
- Published in:
- Endocrinology, 2021, v. 162, n. 10, p. 1, doi. 10.1210/endocr/bqab136
- By:
- Publication type:
- Article
Targeting cellular senescence with senotherapeutics: senolytics and senomorphics.
- Published in:
- FEBS Journal, 2023, v. 290, n. 5, p. 1362, doi. 10.1111/febs.16350
- By:
- Publication type:
- Article
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
- Published in:
- Nature, 2006, v. 444, n. 7122, p. 1038, doi. 10.1038/nature05456
- By:
- Publication type:
- Article
Identification of HSP90 inhibitors as a novel class of senolytics.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00314-z
- By:
- Publication type:
- Article
TP53/p53 Facilitates Stress-Induced Exosome and Protein Secretion by Adipocytes.
- Published in:
- Diabetes, 2023, v. 72, n. 11, p. 1560, doi. 10.2337/db22-1027
- By:
- Publication type:
- Article
Aging and chronic inflammation: highlights from a multidisciplinary workshop.
- Published in:
- Immunity & Ageing, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12979-023-00352-w
- By:
- Publication type:
- Article
Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.
- Published in:
- PLoS Biology, 2018, v. 16, n. 6, p. 1, doi. 10.1371/journal.pbio.2004663
- By:
- Publication type:
- Article
Mislocalization of XPF-ERCC1 Nuclease Contributes to Reduced DNA Repair in XP-F Patients.
- Published in:
- PLoS Genetics, 2010, v. 6, n. 3, p. 1, doi. 10.1371/journal.pgen.1000871
- By:
- Publication type:
- Article
Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms.
- Published in:
- PLoS Genetics, 2008, v. 4, n. 8, p. 1, doi. 10.1371/journal.pgen.1000161
- By:
- Publication type:
- Article
NF-κB Negatively Impacts the Myogenic Potential of Muscle-derived Stem Cells.
- Published in:
- Molecular Therapy, 2012, v. 20, n. 3, p. 661, doi. 10.1038/mt.2011.261
- By:
- Publication type:
- Article
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Strategies to Prevent or Remediate Cancer and Treatment-Related Aging.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Case Report: Identification of a Heterozygous XPA c.553C>T Mutation Causing Neurological Impairment in a Case of Xeroderma Pigmentosum Complementation Group A.
- Published in:
- Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.717361
- By:
- Publication type:
- Article
Dedifferentiation rescues senescence of progeria cells but only while pluripotent.
- Published in:
- Stem Cell Research & Therapy, 2011, v. 2, n. 3, p. 1, doi. 10.1186/scrt69
- By:
- Publication type:
- Article
Extending human healthspan and longevity: a symposium report.
- Published in:
- Annals of the New York Academy of Sciences, 2022, v. 1507, n. 1, p. 70, doi. 10.1111/nyas.14681
- By:
- Publication type:
- Article
NF-κB in Aging and Disease.
- Published in:
- Aging & Disease, 2011, v. 2, n. 6, p. 449
- By:
- Publication type:
- Article
Cell Autonomous and Nonautonomous Mechanisms Drive Hematopoietic Stem/progenitor Cell Loss in the Absence of DNA Repair.
- Published in:
- Stem Cells, 2013, v. 31, n. 3, p. 511, doi. 10.1002/stem.1261
- By:
- Publication type:
- Article
Creating the Next Generation of Translational Geroscientists.
- Published in:
- Journal of the American Geriatrics Society, 2019, v. 67, n. 9, p. 1934, doi. 10.1111/jgs.16055
- By:
- Publication type:
- Article
The Clinical Potential of Senolytic Drugs.
- Published in:
- Journal of the American Geriatrics Society, 2017, v. 65, n. 10, p. 2297, doi. 10.1111/jgs.14969
- By:
- Publication type:
- Article
Correction: Impaired Genome Maintenance Suppresses the Growth HormoneInsulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome.
- Published in:
- 2008
- By:
- Publication type:
- Correction notice
Impaired Genome Maintenance Suppresses the Growth Hormone--Insulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome.
- Published in:
- PLoS Biology, 2007, v. 5, n. 1, p. 23, doi. 10.1371/journal.pbio.0050002
- By:
- Publication type:
- Article
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32552-1
- By:
- Publication type:
- Article
Choline phosphate cytidylyltransferase-α is a novel antigen detected by the anti-ERCC1 antibody 8F1 with biomarker value in patients with lung and head and neck squamous cell carcinomas.
- Published in:
- 2014
- By:
- Publication type:
- journal article
Choline phosphate cytidylyltransferase-α is a novel antigen detected by the anti-ERCC1 antibody 8F1 with biomarker value in patients with lung and head and neck squamous cell carcinomas.
- Published in:
- Cancer (0008543X), 2014, v. 120, n. 12, p. 1898, doi. 10.1002/cncr.28643
- By:
- Publication type:
- Article
mTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.
- Published in:
- Journal of Orthopaedic Research, 2017, v. 35, n. 7, p. 1375, doi. 10.1002/jor.23409
- By:
- Publication type:
- Article
Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration.
- Published in:
- Journal of Orthopaedic Research, 2013, v. 31, n. 7, p. 1150, doi. 10.1002/jor.22320
- By:
- Publication type:
- Article
An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints.
- Published in:
- Journal of Orthopaedic Research, 2013, v. 31, n. 6, p. 831, doi. 10.1002/jor.22204
- By:
- Publication type:
- Article
Accelerated aging of intervertebral discs in a mouse model of progeria.
- Published in:
- Journal of Orthopaedic Research, 2010, v. 28, n. 12, p. 1600, doi. 10.1002/jor.21153
- By:
- Publication type:
- Article
Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1<sup>-/-</sup> mice.
- Published in:
- EMBO Journal, 2005, v. 24, n. 4, p. 861, doi. 10.1038/sj.emboj.7600542
- By:
- Publication type:
- Article
The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.
- Published in:
- EMBO Journal, 2001, v. 20, n. 22, p. 6540, doi. 10.1093/emboj/20.22.6540
- By:
- Publication type:
- Article
NF-κB inhibition delays DNA damage- induced senescence and aging in mice.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 7, p. 2601, doi. 10.1172/JCI45785
- By:
- Publication type:
- Article
Geriatric bioscience.
- Published in:
- 2008
- By:
- Publication type:
- Book Review
In vivo detection and replication studies of α-anomeric lesions of 2'-deoxyribonucleosides.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 17, p. 8314, doi. 10.1093/nar/gkv725
- By:
- Publication type:
- Article
Endogenous formation and repair of oxidatively induced G[8-5 m]T intrastrand cross-link lesion.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 15, p. 7368, doi. 10.1093/nar/gks357
- By:
- Publication type:
- Article
Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice.
- Published in:
- PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0179270
- By:
- Publication type:
- Article
Cellular Senescence in Obesity and Associated Complications: a New Therapeutic Target.
- Published in:
- Current Diabetes Reports, 2022, v. 22, n. 11, p. 537, doi. 10.1007/s11892-022-01493-w
- By:
- Publication type:
- Article
The Role of Senescent Cells in Acquired Drug Resistance and Secondary Cancer in BRAFi-Treated Melanoma.
- Published in:
- Cancers, 2021, v. 13, n. 9, p. 2241, doi. 10.3390/cancers13092241
- By:
- Publication type:
- Article
<italic>ERCC4</italic> variants identified in a cohort of patients with segmental progeroid syndromes.
- Published in:
- Human Mutation, 2018, v. 39, n. 2, p. 255, doi. 10.1002/humu.23367
- By:
- Publication type:
- Article
Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues.
- Published in:
- GeroScience, 2020, v. 42, n. 3, p. 951, doi. 10.1007/s11357-020-00185-1
- By:
- Publication type:
- Article
Deficiency of DNA repair nuclease ERCC1-XPF promotes prostate cancer progression in a tissue recombination model.
- Published in:
- Prostate, 2012, v. 72, n. 11, p. 1214, doi. 10.1002/pros.22472
- By:
- Publication type:
- Article
Clinical validation of C<sub>12</sub>FDG as a marker associated with senescence and osteoarthritic phenotypes.
- Published in:
- Aging Cell, 2024, v. 23, n. 5, p. 1, doi. 10.1111/acel.14113
- By:
- Publication type:
- Article
Targeted clearance of p21‐ but not p16‐positive senescent cells prevents radiation‐induced osteoporosis and increased marrow adiposity.
- Published in:
- Aging Cell, 2022, v. 21, n. 5, p. 1, doi. 10.1111/acel.13602
- By:
- Publication type:
- Article