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REGULATORS OF G-PROTEIN SIGNALLING AS NEW CENTRAL NERVOUS SYSTEM DRUG TARGETS.
- Published in:
- Nature Reviews Drug Discovery, 2002, v. 1, n. 3, p. 187, doi. 10.1038/nrd747
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- Publication type:
- Article
How New Developments in Pharmacology Receptor Theory Are Changing (Our Understanding of) Hypertension Therapy.
- Published in:
- American Journal of Hypertension, 2024, v. 37, n. 4, p. 248, doi. 10.1093/ajh/hpad121
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- Publication type:
- Article
Prevention of bleomycin‐induced lung fibrosis via inhibition of the MRTF/SRF transcription pathway.
- Published in:
- Pharmacology Research & Perspectives, 2022, v. 10, n. 6, p. 1, doi. 10.1002/prp2.1028
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- Publication type:
- Article
Spermine in semen of male sea lamprey acts as a sex pheromone.
- Published in:
- PLoS Biology, 2019, v. 17, n. 7, p. 1, doi. 10.1371/journal.pbio.3000332
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- Publication type:
- Article
Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks.
- Published in:
- Microarrays (2076-3905), 2016, v. 5, n. 2, p. 13, doi. 10.3390/microarrays5020013
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- Publication type:
- Article
IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels.
- Published in:
- Nucleic Acids Research, 2009, v. 37, n. suppl_1, p. D680, doi. 10.1093/nar/gkn728
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- Publication type:
- Article
Gα Subunit Coordinates with Ephrin-B to Balance Self-Renewal and Differentiation in Neural Progenitor Cells.
- Published in:
- Stem Cells, 2010, v. 28, n. 9, p. 1581, doi. 10.1002/stem.474
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- Publication type:
- Article
Novel Peptide Ligands of RGS4 from a Focused One-Bead, One-Compound Library.
- Published in:
- Chemical Biology & Drug Design, 2008, v. 72, n. 2, p. 111, doi. 10.1111/j.1747-0285.2008.00687.x
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- Publication type:
- Article
Mechanism of Action and Structural Requirements of Constrained Peptide Inhibitors of RGS Proteins.
- Published in:
- Chemical Biology & Drug Design, 2006, v. 67, n. 4, p. 266, doi. 10.1111/j.1747-0285.2006.00373.x
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- Publication type:
- Article
FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex.
- Published in:
- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0123581
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- Publication type:
- Article
Reversal of Chronic Renal Hypertension: Role of Salt and Water Excretion.
- Published in:
- Proceedings of the Society for Experimental Biology & Medicine, 1975, v. 150, n. 1, p. 254, doi. 10.3181/00379727-150-39014
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- Publication type:
- Article
Identification of Thieno[3,2-b]Pyrrole Derivatives as Novel Small Molecule Inhibitors of Neurotropic Alphaviruses.
- Published in:
- Journal of Infectious Diseases, 2009, v. 199, n. 7, p. 950, doi. 10.1086/597275
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- Publication type:
- Article
Sensitization of human α<sub>1</sub>- and α<sub>2</sub>-adrenergic venous responses by guanadrel sulfate.
- Published in:
- Clinical Pharmacology & Therapeutics, 1990, v. 48, n. 5, p. 537, doi. 10.1038/clpt.1990.190
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- Publication type:
- Article
Inhibition of the Myocardin-Related Transcription Factor Pathway Increases Efficacy of Trametinib in NRAS -Mutant Melanoma Cell Lines.
- Published in:
- Cancers, 2021, v. 13, n. 9, p. 2012, doi. 10.3390/cancers13092012
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- Publication type:
- Article
Retraction: Mouse models of GNAO1-associated movement disorder: Allele- and sex-specific differences in phenotypes.
- Published in:
- 2021
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- Publication type:
- Correction Notice
Gαi2-mediated protection from ischaemic injury is modulated by endogenous RGS proteins in the mouse heart.
- Published in:
- Cardiovascular Research, 2011, v. 91, n. 1, p. 45, doi. 10.1093/cvr/cvr054
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- Publication type:
- Article
Targeting ATP12A, α Nongastric Proton Pump α Subunit, for Idiopathic Pulmonary Fibrosis Treatment.
- Published in:
- American Journal of Respiratory Cell & Molecular Biology, 2023, v. 68, n. 6, p. 638, doi. 10.1165/rcmb.2022-0264OC
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- Publication type:
- Article
A Glowing Opportunity to Target YAP in Lung Fibrosis.
- Published in:
- American Journal of Respiratory Cell & Molecular Biology, 2022, v. 67, n. 1, p. 1, doi. 10.1165/rcmb.2022-0082ED
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- Publication type:
- Article
Phagocyte-derived catecholamines enhance acute inflammatory injury.
- Published in:
- Nature, 2007, v. 449, n. 7163, p. 721, doi. 10.1038/nature06185
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- Publication type:
- Article
Small Molecule Protein–Protein Interaction Inhibitors as CNS Therapeutic Agents: Current Progress and Future Hurdles.
- Published in:
- Neuropsychopharmacology, 2009, v. 34, n. 1, p. 126, doi. 10.1038/npp.2008.151
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- Publication type:
- Article
Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46531-y
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- Publication type:
- Article
The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in Kras<sup>G12D</sup>; Pdx1-Cre (KC) mice.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43430-0
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- Publication type:
- Article
Conditional disruption of interactions between Galphai2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury.
- Published in:
- BMC Pharmacology & Toxicology, 2014, v. 15, n. 1, p. 1, doi. 10.1186/2050-6511-15-29
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- Publication type:
- Article
Inhibition of the Rho/MRTF pathway improves the response of BRAF‐resistant melanoma to PD1/PDL1 blockade.
- Published in:
- International Journal of Cancer, 2024, v. 155, n. 7, p. 1303, doi. 10.1002/ijc.35056
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- Publication type:
- Article
How does a key fit a flexible lock? Structure and dynamics in receptor function.
- Published in:
- BioEssays, 1989, v. 11, n. 5, p. 136, doi. 10.1002/bies.950110506
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- Publication type:
- Article
Mice With Monoallelic GNAO1 Loss Exhibit Reduced Inhibitory Synaptic Input to Cerebellar Purkinje Cells.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2992
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- Publication type:
- Article
Phase-Locked Signals Elucidate Circuit Architecture of an Oscillatory Pathway.
- Published in:
- PLoS Computational Biology, 2010, v. 6, n. 12, p. 1, doi. 10.1371/journal.pcbi.1001040
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- Publication type:
- Article
COVID-19—A Theory of Autoimmunity Against ACE-2 Explained.
- Published in:
- Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.582166
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- Publication type:
- Article
Characterization and mechanistic investigation of CCG-4986, a small molecule RGS4 inhibitor.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A431, doi. 10.1096/fasebj.21.5.a431
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- Publication type:
- Article
Development of a Time Resolved FRET High-Throughput Assay to Identify Inhibitors of the RGS4/Gαo Interaction.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A431, doi. 10.1096/fasebj.21.5.a431-d
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- Publication type:
- Article
Biphasic regulation of mu-opioid signaling to adenylyl cyclase by GTPase accelerating protein (GAP) activity of RGS7.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A430, doi. 10.1096/fasebj.21.5.a430
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- Publication type:
- Article
Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Gα subtype dependent.
- Published in:
- Journal of Neurochemistry, 2010, v. 112, n. 4, p. 1026, doi. 10.1111/j.1471-4159.2009.06519.x
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- Publication type:
- Article
In vitro and in vivo delivery of a sustained release nanocarrier-based formulation of an MRTF/SRF inhibitor in conjunctival fibrosis.
- Published in:
- Journal of Nanobiotechnology, 2018, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12951-018-0425-3
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- Publication type:
- Article
Regulator of G‐Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for l‐Dopa‐induced dyskinesia.
- Published in:
- British Journal of Pharmacology, 2023, v. 180, n. 7, p. 927, doi. 10.1111/bph.15730
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- Publication type:
- Article
Role of signalling molecules in behaviours mediated by the δ opioid receptor agonist SNC80.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele.
- Published in:
- 2008
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- Publication type:
- journal article
Resistance to Diet-Induced Obesity and Improved Insulin Sensitivity in Mice With a Regulator of G Protein Signaling--Insensitive G184S Gnai2 Allele.
- Published in:
- Diabetes, 2008, v. 57, n. 1, p. 77, doi. 10.2337/db07-0599
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- Publication type:
- Article
Under the microscope: Single molecule symposium at the University of Michigan, 2006.
- Published in:
- Biopolymers, 2007, v. 85, n. 2, p. 106, doi. 10.1002/bip.20621
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- Publication type:
- Article
Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics.
- Published in:
- Integrative Biology, 2013, v. 5, n. 7, p. 932, doi. 10.1039/c3ib40032h
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- Publication type:
- Article
BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors.
- Published in:
- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.766794
- By:
- Publication type:
- Article
Mouse models of GNAO1-associated movement disorder: Allele- and sex-specific differences in phenotypes.
- Published in:
- PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0211066
- By:
- Publication type:
- Article
Optimisation of Intestinal Fibrosis and Survival in the Mouse S. Typhimurium Model for Anti-fibrotic Drug Discovery and Preclinical Applications.
- Published in:
- Journal of Crohn's & Colitis, 2017, v. 11, n. 6, p. 724, doi. 10.1093/ecco-jcc/jjw210
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- Publication type:
- Article
Depicting a protein’s two faces: GPCR classification by phylogenetic tree-based HMMs
- Published in:
- FEBS Letters, 2003, v. 554, n. 1/2, p. 95, doi. 10.1016/S0014-5793(03)01112-8
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- Publication type:
- Article
Interplay of cysteine exposure and global protein dynamics in small‐molecule recognition by a regulator of G‐protein signaling protein.
- Published in:
- Proteins, 2019, v. 87, n. 2, p. 146, doi. 10.1002/prot.25642
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- Publication type:
- Article
Cover Image, Volume 87, Issue 2.
- Published in:
- Proteins, 2019, v. 87, n. 2, p. C1, doi. 10.1002/prot.25633
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- Publication type:
- Article
Diabetic neuropathy: inhibitory G protein dysfunction involves PKC-dependent phosphorylation of G<sub>oα</sub>.
- Published in:
- Journal of Neurochemistry, 2003, v. 86, n. 4, p. 1006, doi. 10.1046/j.1471-4159.2003.01912.x
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- Publication type:
- Article
Coupling Efficacy and Selectivity of the Human μ-Opioid Receptor Expressed as Receptor—Gα Fusion Proteins in Escherichia coli.
- Published in:
- Journal of Neurochemistry, 2000, v. 75, n. 3, p. 1190, doi. 10.1046/j.1471-4159.2000.0751190.x
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- Publication type:
- Article
Role of Rho/MRTF in Aggressive Vemurafenib-Resistant Murine Melanomas and Immune Checkpoint Upregulation.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13785, doi. 10.3390/ijms241813785
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- Publication type:
- Article
GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.
- Published in:
- Bioinformatics, 2010, v. 26, n. 14, p. 1804, doi. 10.1093/bioinformatics/btq264
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- Publication type:
- Article
Differential Control of Opioid Antinociception to Thermal Stimuli in a Knock-In Mouse Expressing Regulator of G-Protein Signaling-Insensitive Gα<sub>o</sub> Protein.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 10, p. 4369, doi. 10.1523/JNEUROSCI.5470-12.2013
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- Publication type:
- Article