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Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active.
Published in:
Angewandte Chemie, 2021, v. 133, n. 26, p. 14778, doi. 10.1002/ange.202103711
By:
- Brasnett, Amelia;
- Pfeffer, Inga;
- Brewitz, Lennart;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Tumber, Anthony;
- McDonough, Michael A.;
- Schofield, Christopher J.
Publication type:
Article
Molecular Insight into the Mg2+‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.
Published in:
Angewandte Chemie, 2018, v. 130, n. 23, p. 6926, doi. 10.1002/ange.201800855
By:
- Awakawa, Takayoshi;
- Mori, Takahiro;
- Nakashima, Yu;
- Zhai, Rui;
- Wong, Chin Piow;
- Hillwig, Matthew L.;
- Liu, Xinyu;
- Abe, Ikuro
Publication type:
Article
Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.
Published in:
Angewandte Chemie, 2018, v. 130, n. 2, p. 569, doi. 10.1002/ange.201710682
By:
- Wong, Chin Piow;
- Awakawa, Takayoshi;
- Nakashima, Yu;
- Mori, Takahiro;
- Zhu, Qin;
- Liu, Xinyu;
- Abe, Ikuro
Publication type:
Article
Phenolic Derivatives with Anti‐Acetylcholinesterase Inhibitory Activities from Galeola nudifolia in Vietnam.
Published in:
Chemistry & Biodiversity, 2023, v. 20, n. 12, p. 1, doi. 10.1002/cbdv.202301482
By:
- Do, Kiep Minh;
- Nakashima, Yu;
- Kodama, Takeshi;
- Lee, Yuan‐E;
- Nguyen, Hien Minh;
- Ikumi, Naotaka;
- Morita, Hiroyuki
Publication type:
Article
Molecular Insight into the Mg2+‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.
Published in:
Angewandte Chemie International Edition, 2018, v. 57, n. 23, p. 6810, doi. 10.1002/anie.201800855
By:
- Awakawa, Takayoshi;
- Mori, Takahiro;
- Nakashima, Yu;
- Zhai, Rui;
- Wong, Chin Piow;
- Hillwig, Matthew L.;
- Liu, Xinyu;
- Abe, Ikuro
Publication type:
Article
Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.
Published in:
Angewandte Chemie International Edition, 2018, v. 57, n. 2, p. 560, doi. 10.1002/anie.201710682
By:
- Wong, Chin Piow;
- Awakawa, Takayoshi;
- Nakashima, Yu;
- Mori, Takahiro;
- Zhu, Qin;
- Liu, Xinyu;
- Abe, Ikuro
Publication type:
Article
Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-27971-z
By:
- Wang, Xiao-Hui;
- Gao, Bo-Wen;
- Nakashima, Yu;
- Mori, Takahiro;
- Zhang, Zhong-Xiu;
- Kodama, Takeshi;
- Lee, Yuan-E;
- Zhang, Ze-Kun;
- Wong, Chin-Piow;
- Liu, Qian-Qian;
- Qi, Bo-Wen;
- Wang, Juan;
- Li, Jun;
- Liu, Xiao;
- Abe, Ikuro;
- Morita, Hiroyuki;
- Tu, Peng-Fei;
- Shi, She-Po
Publication type:
Article
2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26673-2
By:
- Nakashima, Yu;
- Brewitz, Lennart;
- Tumber, Anthony;
- Salah, Eidarus;
- Schofield, Christopher J.
Publication type:
Article
Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.
Published in:
ChemMedChem, 2021, v. 16, n. 13, p. 2082, doi. 10.1002/cmdc.202100133
By:
- Figg, William D.;
- McDonough, Michael A.;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Zhang, Zhihong;
- Holt‐Martyn, James P.;
- Krajnc, Alen;
- Schofield, Christopher J.
Publication type:
Article
Which modality is better to diagnose high-grade transformation in retroperitoneal liposarcoma? Comparison of computed tomography, positron emission tomography, and magnetic resonance imaging.
Published in:
International Journal of Clinical Oncology, 2023, v. 28, n. 3, p. 482, doi. 10.1007/s10147-022-02287-6
By:
- Nakashima, Yu;
- Yokoyama, Yukihiro;
- Ogawa, Hiroshi;
- Sakakibara, Ayako;
- Sunagawa, Masaki;
- Nishida, Yoshihiro;
- Mizuno, Takashi;
- Yamaguchi, Junpei;
- Onoe, Shunsuke;
- Watanabe, Nobuyuki;
- Kawakatsu, Shoji;
- Igami, Tsuyoshi;
- Ebata, Tomoki
Publication type:
Article
Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40232-x
By:
- Nakashima, Yu;
- Kawakami, Atsushi;
- Ogasawara, Yasushi;
- Maeki, Masatoshi;
- Tokeshi, Manabu;
- Dairi, Tohru;
- Morita, Hiroyuki
Publication type:
Article
Physiological and Psychological Effects of Volatile Organic Compounds from Dried Common Rush (Juncus effusus L. var. decipiens Buchen.) on Humans.
Published in:
International Journal of Environmental Research & Public Health, 2022, v. 19, n. 3, p. 1856, doi. 10.3390/ijerph19031856
By:
- Sun, Minkai;
- Nakashima, Taisuke;
- Yoshimura, Yuri;
- Honden, Akiyoshi;
- Nakagawa, Toshinori;
- Nakashima, Yu;
- Kawaguchi, Makoto;
- Takamori, Yukimitsu;
- Koshi, Yoshitaka;
- Sawada, Rimpei;
- Nishida, Shinsuke;
- Ohnuki, Koichiro;
- Shimizu, Kuniyoshi
Publication type:
Article
A Tryptophan Prenyltransferase with Broad Substrate Tolerance from Bacillus subtilis subsp. natto.
Published in:
ChemBioChem, 2018, v. 19, n. 13, p. 1396, doi. 10.1002/cbic.201800174
By:
- Sugita, Tomotoshi;
- Okada, Masahiro;
- Nakashima, Yu;
- Tian, Tian;
- Abe, Ikuro
Publication type:
Article
Innenrücktitelbild: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. 40/2024).
Published in:
Angewandte Chemie, 2024, v. 136, n. 40, p. 1, doi. 10.1002/ange.202414504
By:
- Wu, Yue;
- Chen, Yafen;
- Corner, Thomas P.;
- Nakashima, Yu;
- Salah, Eidarus;
- Li, Zhihong;
- Zhang, Linjian;
- Yang, Le;
- Tumber, Anthony;
- Sun, Zhuoli;
- Wen, Yukang;
- Zhong, Ailin;
- Yang, Fulai;
- Li, Xiang;
- Zhang, Zhihong;
- Schofield, Christopher J.;
- Zhang, Xiaojin
Publication type:
Article
A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.
Published in:
Angewandte Chemie, 2024, v. 136, n. 40, p. 1, doi. 10.1002/ange.202410438
By:
- Wu, Yue;
- Chen, Yafen;
- Corner, Thomas P.;
- Nakashima, Yu;
- Salah, Eidarus;
- Li, Zhihong;
- Zhang, Linjian;
- Yang, Le;
- Tumber, Anthony;
- Sun, Zhuoli;
- Wen, Yukang;
- Zhong, Ailin;
- Yang, Fulai;
- Li, Xiang;
- Zhang, Zhihong;
- Schofield, Christopher J.;
- Zhang, Xiaojin
Publication type:
Article
A human protein hydroxylase that accepts D-residues.
Published in:
Communications Chemistry, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42004-020-0290-5
By:
- Choi, Hwanho;
- Hardy, Adam P.;
- Leissing, Thomas M.;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Ge, Wei;
- Markoulides, Marios;
- Scotti, John S.;
- Gerken, Philip A.;
- Thorbjornsrud, Helen;
- Kang, Dahye;
- Hong, Sungwoo;
- Lee, Joongoo;
- McDonough, Michael A.;
- Park, Hwangseo;
- Schofield, Christopher J.
Publication type:
Article
Inside Back Cover: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. Int. Ed. 40/2024).
Published in:
Angewandte Chemie International Edition, 2024, v. 63, n. 40, p. 1, doi. 10.1002/anie.202414504
By:
- Wu, Yue;
- Chen, Yafen;
- Corner, Thomas P.;
- Nakashima, Yu;
- Salah, Eidarus;
- Li, Zhihong;
- Zhang, Linjian;
- Yang, Le;
- Tumber, Anthony;
- Sun, Zhuoli;
- Wen, Yukang;
- Zhong, Ailin;
- Yang, Fulai;
- Li, Xiang;
- Zhang, Zhihong;
- Schofield, Christopher J.;
- Zhang, Xiaojin
Publication type:
Article
A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.
Published in:
Angewandte Chemie International Edition, 2024, v. 63, n. 40, p. 1, doi. 10.1002/anie.202410438
By:
- Wu, Yue;
- Chen, Yafen;
- Corner, Thomas P.;
- Nakashima, Yu;
- Salah, Eidarus;
- Li, Zhihong;
- Zhang, Linjian;
- Yang, Le;
- Tumber, Anthony;
- Sun, Zhuoli;
- Wen, Yukang;
- Zhong, Ailin;
- Yang, Fulai;
- Li, Xiang;
- Zhang, Zhihong;
- Schofield, Christopher J.;
- Zhang, Xiaojin
Publication type:
Article
Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active.
Published in:
Angewandte Chemie International Edition, 2021, v. 60, n. 26, p. 14657, doi. 10.1002/anie.202103711
By:
- Brasnett, Amelia;
- Pfeffer, Inga;
- Brewitz, Lennart;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Tumber, Anthony;
- McDonough, Michael A.;
- Schofield, Christopher J.
Publication type:
Article
Using a Minimal Parameter Set for Early Diagnosis of Hemophagocytic Lymphohistiocytosis in Non-European Children.
Published in:
2022
By:
- Yu Nakashima;
- Hiroshi Koga
Publication type:
Case Study
Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164468
By:
- Nakashima, Yu;
- Egami, Yoko;
- Kimura, Miki;
- Wakimoto, Toshiyuki;
- Abe, Ikuro
Publication type:
Article
Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02371-w
By:
- Yu Nakashima;
- Takahiro Mori;
- Hitomi Nakamura;
- Takayoshi Awakawa;
- Shotaro Hoshino;
- Ikuro Abe;
- Miki Senda;
- Toshiya Senda
Publication type:
Article
Arginase inhibitory activities of guaiane sesquiterpenoids from Curcuma comosa rhizomes.
Published in:
Journal of Natural Medicines, 2023, v. 77, n. 4, p. 891, doi. 10.1007/s11418-023-01731-9
By:
- Hoang, Nhat Nam;
- Kodama, Takeshi;
- Nakashima, Yu;
- Do, Kiep Minh;
- Hnin, Saw Yu Yu;
- Lee, Yuan-E;
- Prema;
- Ikumi, Naotaka;
- Morita, Hiroyuki
Publication type:
Article
Enzymatic formation of a prenyl β-carboline by a fungal indole prenyltransferase.
Published in:
Journal of Natural Medicines, 2022, v. 76, n. 4, p. 873, doi. 10.1007/s11418-022-01635-0
By:
- Hamdy, Sherif Ahmed;
- Kodama, Takeshi;
- Nakashima, Yu;
- Han, Xiaojie;
- Matsui, Takashi;
- Morita, Hiroyuki
Publication type:
Article
Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas – Implications for the progression of EGFR-mutated lung adenocarcinomas.
Published in:
PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0215237
By:
- Matsumura, Mai;
- Okudela, Koji;
- Nakashima, Yu;
- Mitsui, Hideaki;
- Denda-Nagai, Kaori;
- Suzuki, Takehisa;
- Arai, Hiromasa;
- Umeda, Shigeaki;
- Tateishi, Yoko;
- Koike, Chihiro;
- Kataoka, Toshiaki;
- Irimura, Tatsuro;
- Ohashi, Kenichi
Publication type:
Article
Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2.
Published in:
Proteins, 2023, v. 91, n. 11, p. 1510, doi. 10.1002/prot.26541
By:
- Figg, William D.;
- Fiorini, Giorgia;
- Chowdhury, Rasheduzzaman;
- Nakashima, Yu;
- Tumber, Anthony;
- McDonough, Michael A.;
- Schofield, Christopher J.
Publication type:
Article
Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.
Published in:
Nature Chemical Biology, 2014, v. 10, n. 8, p. 648, doi. 10.1038/nchembio.1573
By:
- Wakimoto, Toshiyuki;
- Egami, Yoko;
- Nakashima, Yu;
- Wakimoto, Yukihiko;
- Mori, Takahiro;
- Awakawa, Takayoshi;
- Ito, Takuya;
- Kenmoku, Hiromichi;
- Asakawa, Yoshinori;
- Piel, Jörn;
- Abe, Ikuro
Publication type:
Article
Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial.
Published in:
Nutrients, 2020, v. 12, n. 1, p. 4, doi. 10.3390/nu12010004
By:
- Furushima, Daisuke;
- Nishimura, Takuma;
- Takuma, Norikata;
- Iketani, Ryo;
- Mizuno, Tomohito;
- Matsui, Yuji;
- Yamaguchi, Tohru;
- Nakashima, Yu;
- Yamamoto, Shinji;
- Hibi, Masanobu;
- Yamada, Hiroshi
Publication type:
Article

Found: 28

Human Oxygenase Variants Employing a Single Protein Fe<sup>II</sup> Ligand Are Catalytically Active.

Molecular Insight into the Mg<sup>2+</sup>‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.

Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.

Phenolic Derivatives with Anti‐Acetylcholinesterase Inhibitory Activities from Galeola nudifolia in Vietnam.

Molecular Insight into the Mg<sup>2+</sup>‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.

Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.

Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood.

2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.

Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.

Which modality is better to diagnose high-grade transformation in retroperitoneal liposarcoma? Comparison of computed tomography, positron emission tomography, and magnetic resonance imaging.

Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism.

Physiological and Psychological Effects of Volatile Organic Compounds from Dried Common Rush (Juncus effusus L. var. decipiens Buchen.) on Humans.

A Tryptophan Prenyltransferase with Broad Substrate Tolerance from Bacillus subtilis subsp. natto.

Innenrücktitelbild: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. 40/2024).

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.

A human protein hydroxylase that accepts D-residues.

Inside Back Cover: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. Int. Ed. 40/2024).

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.

Human Oxygenase Variants Employing a Single Protein Fe<sup>II</sup> Ligand Are Catalytically Active.

Using a Minimal Parameter Set for Early Diagnosis of Hemophagocytic Lymphohistiocytosis in Non-European Children.

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’.

Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.

Arginase inhibitory activities of guaiane sesquiterpenoids from Curcuma comosa rhizomes.

Enzymatic formation of a prenyl β-carboline by a fungal indole prenyltransferase.

Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas – Implications for the progression of EGFR-mutated lung adenocarcinomas.

Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2.

Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.

Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial.