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Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 369, doi. 10.3390/ijms23010369
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- Article
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells.
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- Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01597-8
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- Article
NOXA Accentuates Apoptosis Induction by a Novel Histone Deacetylase Inhibitor.
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- Cancers, 2023, v. 15, n. 14, p. 3650, doi. 10.3390/cancers15143650
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- Article
HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1.
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- Cancers, 2019, v. 11, n. 10, p. 1436, doi. 10.3390/cancers11101436
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- Article
Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells.
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- Molecular Oncology, 2024, v. 18, n. 8, p. 1958, doi. 10.1002/1878-0261.13638
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- Article
Structural Insights into the Interaction of Heme with Protein Tyrosine Kinase JAK2**.
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- ChemBioChem, 2021, v. 22, n. 5, p. 861, doi. 10.1002/cbic.202000730
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- Article
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3.
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- Archives of Toxicology, 2022, v. 96, n. 1, p. 177, doi. 10.1007/s00204-021-03174-1
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- Article
Novel insight into mechanisms for ATR activation by chromatin structures.
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- Archives of Toxicology, 2021, v. 95, n. 10, p. 3433, doi. 10.1007/s00204-021-03133-w
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- Article