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Dynamic Nuclear Polarization NMR Spectroscopy: Revealing Multiple Conformations in Lipid-Anchored Peptide Vaccines.
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- Angewandte Chemie International Edition, 2013, v. 52, n. 41, p. 10905, doi. 10.1002/anie.201303374
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- Article
DT‐02‐06: NOVEL ALPHA‐SYNUCLEIN POSITRON EMISSION TOMOGRAPHY (PET) TRACERS FOR THE DIAGNOSIS OF PARKINSON'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1671, doi. 10.1016/j.jalz.2018.07.015
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IC‐P‐220: CLINICAL UPDATE: <sup>18</sup>F‐PI‐2620, A NEXT GENERATION TAU PET AGENT EVALUATED IN SUBJECTS WITH ALZHEIMER'S DISEASE AND PROGRESSIVE SUPRANUCLEAR PALSY.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P179, doi. 10.1016/j.jalz.2018.06.2287
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- Article
PRECLINICAL CHARACTERIZATION OF PI-2620, A NOVEL TAU PET TRACER FOR DETECTION OF TAU IN AD AND OTHER TAUOPATHIES.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P141, doi. 10.1016/j.jalz.2017.06.2567
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- Article
PRECLINICAL CHARACTERIZATION OF PI-2620, A NOVEL TAU PET TRACER FOR DETECTION OF TAU IN AD AND OTHER TAUOPATHIES.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P774, doi. 10.1016/j.jalz.2017.06.1036
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- Article
DEVELOPMENT OF HIGHLY SENSITIVE MSD ASSAYS FOR THE DETECTION OF ANTI-AMYLOID β MONOMER- AND OLIGOMER-SPECIFIC ANTIBODIES IN HUMAN SERUM.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P957, doi. 10.1016/j.jalz.2017.06.1277
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- Article
CHANGES IN TAU PROTEIN LANDSCAPE DURING ALZHEIMER’S DISEASE PROGRESSION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1296, doi. 10.1016/j.jalz.2017.06.1964
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- Article
FIRST-IN-HUMAN PET STUDIES WITH THE NEXT GENERATION TAU AGENT 18-F PI-2620 IN ALZHEIMER’S DISEASE, PROGRESSIVE SUPRANUCLEAR PALSY, AND CONTROLS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P3, doi. 10.1016/j.jalz.2017.06.2625
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- Article
EFFICACY OF ACI-35, A LIPOSOMAL ANTI-PHOSPHO TAU VACCINE IN TWO DIFFERENT MOUSE MODELS OF ALZHEIMER’S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P260, doi. 10.1016/j.jalz.2016.06.468
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- Article
Tau antibodies lacking effector function minimize inflammatory responses while effectively blocking spread of tau pathology.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P503, doi. 10.1016/j.jalz.2015.06.591
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Phospho-tau–specific vaccine for the treatment of tau pathology
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- 2012
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- Abstract
Comparison of toxic beta-amyloid oligomer inhibitors for rescuing memory deficits in APP transgenic mice
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- 2012
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Novel phospho-tau-specific liposome-based vaccines to treat tau pathology
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- 2011
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Selection of an anti-Abeta antibody that binds various forms of Abeta and blocks toxicity both in vitro and in vivo
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- 2009
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- Abstract
The safety profile of ACI-24, an oligo-specific amyloid beta vaccine, demonstrated decrease of large microbleedings in brain of aged Alzheimer's disease mouse model
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- 2009
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- Abstract
O1-06-06: Improved memory capacity of amyloid precursor protein transgenic mice through passive administration of a monoclonal antibody inducing a conformational shift of amyloid-beta
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- 2006
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- Abstract
O1-06-06: Improved memory capacity of amyloid precursor protein transgenic mice through passive administration of a monoclonal antibody inducing a conformational shift of amyloid-beta
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- 2006
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- Abstract
NMR-Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid-verankerten Peptid-Impfstoffen.
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- Angewandte Chemie, 2013, v. 125, n. 41, p. 11106, doi. 10.1002/ange.201303374
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- Article
Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin.
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- Scientific Reports, 2016, p. 39374, doi. 10.1038/srep39374
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- Article
Engineering Amyloid-Like Assemblies from Unstructured Peptides via Site-Specific Lipid Conjugation.
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- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0105641
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- Article
Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy.
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- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072301
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- Article
Development of a Small D-Enantiomeric Alzheimer's Amyloid-b Binding Peptide Ligand for Future In Vivo Imaging Applications.
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- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041457
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- Article
BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease.
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- Journal of Cerebral Blood Flow & Metabolism, 2016, v. 36, n. 7, p. 1281, doi. 10.1177/0271678X15606463
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- Article
Deciphering the role of tau in neurodegeneration using Adeno-Associated Viral (AAV) vectors to express human tau in the mouse forebrain.
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- 2013
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- Abstract
Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35130-y
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- Article
A C-Linked Disaccharide Analogue of Thomsen-Friedenreich Epitope Induces a Strong Immune Response in Mice.
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- Chemistry - A European Journal, 2012, v. 18, n. 28, p. 8578, doi. 10.1002/chem.201200364
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Discovery and preclinical characterization of [<sup>18</sup>F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies.
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- European Journal of Nuclear Medicine & Molecular Imaging, 2019, v. 46, n. 10, p. 2178, doi. 10.1007/s00259-019-04397-2
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An Effector-Reduced Anti-&bgr;-Amyloid (A&bgr;) Antibody with Unique A&bgr; Binding Properties Promotes Neuroprotection and Glial Engulfment of A&bgr;.
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- Journal of Neuroscience, 2012, v. 32, n. 28, p. 9677, doi. 10.1523/JNEUROSCI.4742-11.2012
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