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CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110.
Published in:
Journal of Hematology & Oncology, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13045-020-00865-7
By:
- Domínguez, Juan Manuel;
- Pérez-Chacón, Gema;
- Guillén, María José;
- Muñoz-Alonso, María José;
- Somovilla-Crespo, Beatriz;
- Cibrián, Danay;
- Acosta-Iborra, Bárbara;
- Adrados, Magdalena;
- Muñoz-Calleja, Cecilia;
- Cuevas, Carmen;
- Sánchez-Madrid, Francisco;
- Avilés, Pablo;
- Zapata, Juan M.
Publication type:
Article
Therapeutic potential of an anti-CCR9 mAb evidenced in xenografts of human CCR9<sup>+</sup> tumors.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.825635
By:
- Santamaria, Silvia;
- Delgado, Marisa;
- Botas, Marta;
- Castellano, Eva;
- Corraliza-Gorjon, Isabel;
- Lafuente, Paloma;
- Muñoz-Calleja, Cecilia;
- Toribio, Maria L.;
- Kremer, Leonor;
- Garcia-Sanz, Jose A.
Publication type:
Article
CD4+ T Cell Immune Specificity Changes After Vaccination in Healthy And COVID-19 Convalescent Subjects.
Published in:
Frontiers in Immunology, 2022, p. 1, doi. 10.3389/fimmu.2021.755891
By:
- Esparcia-Pinedo, Laura;
- Martínez-Fleta, Pedro;
- Ropero, Noelia;
- Vera-Tomé, Paula;
- Reyburn, Hugh T.;
- Casasnovas, José M.;
- Rodríguez Frade, José M.;
- Valés-Gómez, Mar;
- Vilches, Carlos;
- Martín-Gayo, Enrique;
- Muñoz-Calleja, Cecilia;
- Sanchez-Madrid, Francisco;
- Alfranca, Arantzazu
Publication type:
Article
A Differential Signature of Circulating miRNAs and Cytokines Between COVID-19 and Community-Acquired Pneumonia Uncovers Novel Physiopathological Mechanisms of COVID-19.
Published in:
Frontiers in Immunology, 2022, v. 12, p. 1, doi. 10.3389/fimmu.2021.815651
By:
- Martínez-Fleta, Pedro;
- Vera-Tomé, Paula;
- Jiménez-Fernández, María;
- Requena, Silvia;
- Roy-Vallejo, Emilia;
- Sanz-García, Ancor;
- Lozano-Prieto, Marta;
- López-Sanz, Celia;
- Vara, Alicia;
- Lancho-Sánchez, Ángel;
- Martín-Gayo, Enrique;
- Muñoz-Calleja, Cecilia;
- Alfranca, Arantzazu;
- González-Álvaro, Isidoro;
- Galván-Román, José María;
- Aspa, Javier;
- de la Fuente, Hortensia;
- Sánchez-Madrid, Francisco
Publication type:
Article
Retrospective comparison between COBE SPECTRA and SPECTRA OPTIA apheresis systems for hematopoietic progenitor cells collection for autologous and allogeneic transplantation in a single center.
Published in:
Journal of Clinical Apheresis, 2020, v. 35, n. 5, p. 453, doi. 10.1002/jca.21826
By:
- López‐Pereira, Patricia;
- Sola Aparicio, Elena;
- Vicuña Andrés, Isabel;
- Cámara Montejano, Carmen;
- Muñoz Calleja, Cecilia;
- Alegre Amor, Adrián;
- Aguado Bueno, Beatriz
Publication type:
Article
P-Selectin preserves immune tolerance in mice and is reduced in human cutaneous lupus.
Published in:
Scientific Reports, 2017, p. 41841, doi. 10.1038/srep41841
By:
- González-Tajuelo, Rafael;
- Silván, Javier;
- Pérez-Frías, Alicia;
- de la Fuente-Fernández, María;
- Tejedor, Reyes;
- Espartero-Santos, Marina;
- Vicente-Rabaneda, Esther;
- Juarranz, Ángeles;
- Muñoz-Calleja, Cecilia;
- Castañeda, Santos;
- Gamallo, Carlos;
- Urzainqui, Ana
Publication type:
Article
Monoclonal Antibody Therapies for Hematological Malignancies: Not Just Lineage-Specific Targets.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2017.01936
By:
- Cuesta-Mateos, Carlos;
- Alcaraz-Serna, Ana;
- Somovilla-Crespo, Beatriz;
- Muñoz-Calleja, Cecilia
Publication type:
Article
NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46322-8
By:
- Tsukalov, Ilya;
- Sánchez-Cerrillo, Ildefonso;
- Rajas, Olga;
- Avalos, Elena;
- Iturricastillo, Gorane;
- Esparcia, Laura;
- Buzón, María José;
- Genescà, Meritxell;
- Scagnetti, Camila;
- Popova, Olga;
- Martin-Cófreces, Noa;
- Calvet-Mirabent, Marta;
- Marcos-Jimenez, Ana;
- Martínez-Fleta, Pedro;
- Delgado-Arévalo, Cristina;
- de los Santos, Ignacio;
- Muñoz-Calleja, Cecilia;
- Calzada, María José;
- González Álvaro, Isidoro;
- Palacios-Calvo, José
Publication type:
Article
Evaluation of Natalizumab Pharmacokinetics and Pharmacodynamics: Toward Individualized Doses.
Published in:
Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.716548
By:
- Serra López-Matencio, Jose M.;
- Pérez García, Yaiza;
- Meca-Lallana, Virginia;
- Juárez-Sánchez, Raquel;
- Ursa, Angeles;
- Vega-Piris, Lorena;
- Pascual-Salcedo, Dora;
- de Vries, Annick;
- Rispens, Theo;
- Muñoz-Calleja, Cecilia
Publication type:
Article
Effect of ibrutinib on CCR7 expression and functionality in chronic lymphocytic leukemia and its implication for the activity of CAP-100, a novel therapeutic anti-CCR7 antibody.
Published in:
Cancer Immunology, Immunotherapy, 2022, v. 71, n. 3, p. 627, doi. 10.1007/s00262-021-03014-2
By:
- Mateu-Albero, Tamara;
- Juárez-Sánchez, Raquel;
- Loscertales, Javier;
- Mol, Wim;
- Terrón, Fernando;
- Muñoz-Calleja, Cecilia;
- Cuesta-Mateos, Carlos
Publication type:
Article
Preclinical activity of anti-CCR7 immunotherapy in patients with high-risk chronic lymphocytic leukemia.
Published in:
Cancer Immunology, Immunotherapy, 2015, v. 64, n. 6, p. 665, doi. 10.1007/s00262-015-1670-z
By:
- Cuesta-Mateos, Carlos;
- Loscertales, Javier;
- Kreutzman, Anna;
- Colom-Fernández, Beatriz;
- Portero-Sáinz, Itxaso;
- Pérez-Villar, Juan;
- Terrón, Fernando;
- Muñoz-Calleja, Cecilia
Publication type:
Article
Immediate Effects of Dasatinib on the Migration and Redistribution of Naïve and Memory Lymphocytes Associated With Lymphocytosis in Chronic Myeloid Leukemia Patients.
Published in:
Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01340
By:
- Colom-Fernández, Beatriz;
- Kreutzman, Anna;
- Marcos-Jiménez, Ana;
- García-Gutiérrez, Valentín;
- Cuesta-Mateos, Carlos;
- Portero-Sainz, Itxaso;
- Pérez-García, Yaiza;
- Casado, Luis Felipe;
- Sánchez-Guijo, Fermín;
- Martínez-López, Joaquín;
- Ayala, Rosa M.;
- Boqué, Concha;
- Xicoy, Blanca;
- Montero, Isabel;
- Soto, César;
- Paz, Raquel;
- Silva, Gabriela;
- Vega-Piris, Lorena;
- Steegmann, Juan Luis;
- Muñoz-Calleja, Cecilia
Publication type:
Article
Ibrutinib Does Not Impact CCR7-Mediated Homeostatic Migration in T-Cells from Chronic Lymphocytic Leukemia Patients.
Published in:
Cancers, 2022, v. 14, n. 11, p. 2729, doi. 10.3390/cancers14112729
By:
- Mateu-Albero, Tamara;
- Marcos-Jimenez, Ana;
- Wissmann, Stefanie;
- Loscertales, Javier;
- Terrón, Fernando;
- Stein, Jens V.;
- Muñoz-Calleja, Cecilia;
- Cuesta-Mateos, Carlos
Publication type:
Article
The NOTCH1/CD44 axis drives pathogenesis in a T cell acute lymphoblastic leukemia model.
Published in:
2018
By:
- García-Peydró, Marina;
- Fuentes, Patricia;
- Mosquera, Marta;
- García-León, María J.;
- Alcain, Juan;
- Rodríguez, Antonio;
- de Miguel, Purificación García;
- Menéndez, Pablo;
- Weijer, Kees;
- Spits, Hergen;
- Scadden, David T.;
- Cuesta-Mateos, Carlos;
- Muñoz-Calleja, Cecilia;
- Sánchez-Madrid, Francisco;
- Toribio, María L.;
- García de Miguel, Purificación
Publication type:
journal article
Of Lymph Nodes and CLL Cells: Deciphering the Role of CCR7 in the Pathogenesis of CLL and Understanding Its Potential as Therapeutic Target.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.662866
By:
- Cuesta-Mateos, Carlos;
- Brown, Jennifer R.;
- Terrón, Fernando;
- Muñoz-Calleja, Cecilia
Publication type:
Article
Novel Germline TET2 Mutations in Two Unrelated Patients with Autoimmune Lymphoproliferative Syndrome-Like Phenotype and Hematologic Malignancy.
Published in:
Journal of Clinical Immunology, 2023, v. 43, n. 1, p. 165, doi. 10.1007/s10875-022-01361-y
By:
- López-Nevado, Marta;
- Ortiz-Martín, Javier;
- Serrano, Cristina;
- Pérez-Saez, María A.;
- López-Lorenzo, José L.;
- Gil-Etayo, Francisco J.;
- Rodríguez-Frías, Edgar;
- Cabrera-Marante, Oscar;
- Morales-Pérez, Pablo;
- Rodríguez-Pinilla, María S.;
- Manso, Rebeca;
- Salgado-Sánchez, Rocío N.;
- Cerdá-Montagud, Ana;
- Quesada-Espinosa, Juan F.;
- Gómez-Rodríguez, María J.;
- Paz-Artal, Estela;
- Muñoz-Calleja, Cecilia;
- Arranz-Sáez, Reyes;
- Allende, Luis M.
Publication type:
Article
Glutathione overproduction mediates lymphoma initiating cells survival and has a sex-dependent effect on lymphomagenesis.
Published in:
Cell Death & Disease, 2024, v. 15, n. 7, p. 1, doi. 10.1038/s41419-024-06923-z
By:
- H.-Alcántara, Alberto;
- Kourani, Omar;
- Marcos-Jiménez, Ana;
- Martínez-Núñez, Patricia;
- Herranz-Martín, Estela;
- Fuentes, Patricia;
- Toribio, María L.;
- Muñoz-Calleja, Cecilia;
- Iglesias, Teresa;
- Campanero, Miguel R.
Publication type:
Article
Evaluation of the novel therapeutic anti‐CCR7 antibody CAP‐100 as an add‐on therapy in chronic lymphocytic leukemia patients receiving venetoclax.
Published in:
Hematological Oncology, 2023, v. 41, n. 5, p. 869, doi. 10.1002/hon.3213
By:
- Mateu‐Albero, Tamara;
- Marcos‐Jimenez, Ana;
- Delgado‐Wicke, Pablo;
- Terrón, Fernando;
- Loscertales, Javier;
- López‐Matencio, José María Serra;
- Muñoz‐Calleja, Cecilia;
- Cuesta‐Mateos, Carlos
Publication type:
Article
Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma.
Published in:
Journal of Hematology & Oncology, 2013, v. 6, n. 1, p. 3, doi. 10.1186/1756-8722-6-89
By:
- Somovilla-Crespo, Beatriz;
- Alfonso-Pérez, Manuel;
- Cuesta-Mateos, Carlos;
- Dios, Cristina Carballo-de;
- Beltrán, Amada E.;
- Terrón, Fernando;
- Pérez-Villar, Juan J.;
- Gamallo-Amat, Carlos;
- Pérez-Chacón, Gema;
- Fernández-Ruiz, Elena;
- Zapata, Juan M.;
- Muñoz-Calleja, Cecilia
Publication type:
Article
PSGL-1, ADAM8, and selectins as potential biomarkers in the diagnostic process of systemic lupus erythematosus and systemic sclerosis: an observational study.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1403104
By:
- San Antonio, Esther;
- Silván, Javier;
- Sevilla-Montero, Javier;
- González-Sánchez, Elena;
- Muñoz-Callejas, Antonio;
- Sánchez-Abad, Inés;
- Ramos-Manzano, Alejandra;
- Muñoz-Calleja, Cecilia;
- González-Álvaro, Isidoro;
- Tomero, Eva G.;
- García-Pérez, Javier;
- García-Vicuña, Rosario;
- Vicente-Rabaneda, Esther F.;
- Castañeda, Santos;
- Urzainqui, Ana
Publication type:
Article
Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16115-w
By:
- Kim, Daehong;
- Park, Giljun;
- Huuhtanen, Jani;
- Lundgren, Sofie;
- Khajuria, Rajiv K.;
- Hurtado, Ana M.;
- Muñoz-Calleja, Cecilia;
- Cardeñoso, Laura;
- Gómez-García de Soria, Valle;
- Chen-Liang, Tzu Hua;
- Eldfors, Samuli;
- Ellonen, Pekka;
- Hannula, Sari;
- Kankainen, Matti;
- Bruck, Oscar;
- Kreutzman, Anna;
- Salmenniemi, Urpu;
- Lönnberg, Tapio;
- Jerez, Andrés;
- Itälä-Remes, Maija
Publication type:
Article

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