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Evaluation of the Effects of Repeat‐Dose Dabrafenib on the Single‐Dose Pharmacokinetics of Rosuvastatin (OATP1B1/1B3 Substrate) and Midazolam (CYP3A4 Substrate).
Published in:
Clinical Pharmacology in Drug Development, 2021, v. 10, n. 9, p. 1054, doi. 10.1002/cpdd.937
By:
- Nebot, Noelia;
- Won, Christina S.;
- Moreno, Victor;
- Muñoz‐Couselo, Eva;
- Lee, Dung‐Yang;
- Gasal, Eduard;
- Bouillaud, Emmanuel
Publication type:
Article
BRAF activation by metabolic stress promotes glycolysis sensitizing NRAS<sup>Q61</sup>-mutated melanomas to targeted therapy.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34907-0
By:
- McGrail, Kimberley;
- Granado-Martínez, Paula;
- Esteve-Puig, Rosaura;
- García-Ortega, Sara;
- Ding, Yuxin;
- Sánchez-Redondo, Sara;
- Ferrer, Berta;
- Hernandez-Losa, Javier;
- Canals, Francesc;
- Manzano, Anna;
- Navarro-Sabaté, Aura;
- Bartrons, Ramón;
- Yanes, Oscar;
- Pérez-Alea, Mileidys;
- Muñoz-Couselo, Eva;
- Garcia-Patos, Vicenç;
- Recio, Juan A.
Publication type:
Article
An algorithm based on immunotherapy discontinuation and liver biopsy spares corticosteroids in two thirds of cases of severe checkpoint inhibitor‐induced liver injury.
Published in:
Alimentary Pharmacology & Therapeutics, 2024, v. 59, n. 7, p. 865, doi. 10.1111/apt.17898
By:
- Riveiro‐Barciela, Mar;
- Barreira‐Díaz, Ana;
- Salcedo, María‐Teresa;
- Callejo‐Pérez, Ana;
- Muñoz‐Couselo, Eva;
- Iranzo, Patricia;
- Ortiz‐Velez, Carolina;
- Cedrés, Susana;
- Díaz‐Mejía, Nely;
- Ruiz‐Cobo, Juan Carlos;
- Morales, Rafael;
- Aguilar‐Company, Juan;
- Zamora, Ester;
- Oliveira, Mafalda;
- Sanz‐Martínez, María‐Teresa;
- Viladomiu, Lluis;
- Martínez‐Gallo, Mónica;
- Felip, Enriqueta;
- Buti, María
Publication type:
Article
Intermittent BRAF inhibition in advanced BRAF mutated melanoma results of a phase II randomized trial.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26572-6
By:
- Gonzalez-Cao, Maria;
- de las Casas, Clara Mayo;
- Oramas, Juana;
- Berciano-Guerrero, Miguel A.;
- de la Cruz, Luis;
- Cerezuela, Pablo;
- Arance, Ana;
- Muñoz-Couselo, Eva;
- Espinosa, Enrique;
- Puertolas, Teresa;
- Beveridge, Roberto Diaz;
- Ochenduszko, Sebastian;
- Villanueva, Maria-Jose;
- Basterretxea, Laura;
- Bellido, Lorena;
- Rodriguez, Delvys;
- Campos, Begoña;
- Montagut, Clara;
- Drozdowskyj, Ana;
- Molina, Miguel A.
Publication type:
Article
Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR.
Published in:
Nature Medicine, 2015, v. 21, n. 7, p. 741, doi. 10.1038/nm.3863
By:
- Vizoso, Miguel;
- Ferreira, Humberto J;
- Lopez-Serra, Paula;
- Carmona, F Javier;
- Martínez-Cardús, Anna;
- Girotti, Maria Romina;
- Villanueva, Alberto;
- Guil, Sonia;
- Moutinho, Catia;
- Liz, Julia;
- Portela, Anna;
- Heyn, Holger;
- Moran, Sebastian;
- Vidal, August;
- Martinez-Iniesta, Maria;
- Manzano, Jose L;
- Fernandez-Figueras, Maria Teresa;
- Elez, Elena;
- Muñoz-Couselo, Eva;
- Botella-Estrada, Rafael
Publication type:
Article
The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies.
Published in:
Nature Genetics, 2015, v. 47, n. 3, p. 250, doi. 10.1038/ng.3218
By:
- Lin, Luping;
- Chan, Elton;
- Olivas, Victor;
- Cade, Lindsay;
- Pazarentzos, Evangelos;
- Asthana, Saurabh;
- Neel, Dana;
- Yan, Jenny Jiacheng;
- Lu, Xinyuan;
- Pham, Luu;
- Wang, Mingxue M;
- Collisson, Eric A;
- Algazi, Alain;
- Bivona, Trever G;
- Muñoz-Couselo, Eva;
- Cortes, Javier;
- Frederick, Dennie T;
- Flaherty, Keith T;
- Cooper, Zachary A;
- Wargo, Jennifer A
Publication type:
Article
Mucosal Melanoma Clinical Management and Prognostic Implications: A Retrospective Cohort Study.
Published in:
Cancers, 2024, v. 16, n. 1, p. 227, doi. 10.3390/cancers16010227
By:
- Clavero-Rovira, Laia;
- Gómez-Tomás, Álvaro;
- Bassas-Freixas, Patricia;
- Bodet, Domingo;
- Ferrer, Berta;
- Hernández-Losa, Javier;
- Muñoz-Couselo, Eva;
- Pérez-Benavente, Assumpció;
- García-Patos, Vicente;
- Ferrándiz-Pulido, Carla
Publication type:
Article
Immune‐related hepatitis related to checkpoint inhibitors: Clinical and prognostic factors.
Published in:
Liver International, 2020, v. 40, n. 8, p. 1906, doi. 10.1111/liv.14489
By:
- Riveiro‐Barciela, Mar;
- Barreira‐Díaz, Ana;
- Vidal‐González, Judit;
- Muñoz‐Couselo, Eva;
- Martínez‐Valle, Fernando;
- Viladomiu, Lluís;
- Mínguez, Beatriz;
- Ortiz‐Velez, Carolina;
- Castells, Lluís;
- Esteban, Rafael;
- Buti, María
Publication type:
Article
STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.
Published in:
Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-1092-0
By:
- Granado-Martínez, Paula;
- Garcia-Ortega, Sara;
- González-Sánchez, Elena;
- McGrail, Kimberley;
- Selgas, Rafael;
- Grueso, Judit;
- Gil, Rosa;
- Naldaiz-Gastesi, Neia;
- Rhodes, Ana C.;
- Hernandez-Losa, Javier;
- Ferrer, Berta;
- Canals, Francesc;
- Villanueva, Josep;
- Méndez, Olga;
- Espinosa-Gil, Sergio;
- Lizcano, José M.;
- Muñoz-Couselo, Eva;
- García-Patos, Vicenç;
- Recio, Juan A.
Publication type:
Article
SEOM-GEM clinical guidelines for cutaneous melanoma (2023).
Published in:
Clinical & Translational Oncology, 2024, v. 26, n. 11, p. 2841, doi. 10.1007/s12094-024-03497-2
By:
- Márquez-Rodas, Iván;
- Muñoz Couselo, Eva;
- Rodríguez Moreno, Juan F.;
- Arance Fernández, Ana Mª;
- Berciano Guerrero, Miguel Ángel;
- Campos Balea, Begoña;
- de la Cruz Merino, Luis;
- Espinosa Arranz, Enrique;
- García Castaño, Almudena;
- Berrocal Jaime, Alfonso
Publication type:
Article
Access to melanoma drugs in Spain: a cross-sectional survey.
Published in:
Clinical & Translational Oncology, 2024, v. 26, n. 10, p. 2572, doi. 10.1007/s12094-024-03501-9
By:
- Gonzalez-Cao, Maria;
- Puertolas, Teresa;
- Manzano, Jose Luis;
- Maldonado, Cayetana;
- Yelamos, Oriol;
- Berciano-Guerrero, Miguel Ángel;
- Cerezuela, Pablo;
- Martin-Liberal, Juan;
- Muñoz-Couselo, Eva;
- Espinosa, Enrique;
- Drozdowskyj, Ana;
- Berrocal, Alfonso;
- Soria, Ainara;
- Marquez-Rodas, Ivan;
- Martin-Algarra, Salvador;
- Quindos, Maria;
- Puig, Susana
Publication type:
Article
Contribution of tumour and immune cells to PD‐L1 expression as a predictive biomarker in metastatic triple‐negative breast cancer: exploratory analysis from KEYNOTE‐119.
Published in:
Journal of Pathology: Clinical Research, 2024, v. 10, n. 3, p. 1, doi. 10.1002/2056-4538.12371
By:
- Cortes, Javier;
- Winer, Eric P;
- Lipatov, Oleg;
- Im, Seock‐Ah;
- Gonçalves, Anthony;
- Muñoz‐Couselo, Eva;
- Lee, Keun Seok;
- Schmid, Peter;
- Tamura, Kenji;
- Testa, Laura;
- Witzel, Isabell;
- Ohtani, Shoichiro;
- Hund, Stephanie;
- Kulangara, Karina;
- Karantza, Vassiliki;
- Mejia, Jaime A;
- Ma, Junshui;
- Jelinic, Petar;
- Huang, Lingkang;
- Pruitt, Scott K
Publication type:
Article
Hepatic sinusoidal obstruction syndrome associated with nivolumab: an uncommon adverse event related to immune checkpoint inhibitors.
Published in:
2021
By:
- Riveiro-Barciela, Mar;
- González-Sans, Didac;
- Marmolejo, David;
- Salcedo, Maria-Teresa;
- Muñoz-Couselo, Eva
Publication type:
Case Study
Vollständiges Ansprechen eines metastasierten Plattenepithelkarzinoms der Haut und mehrerer multipler, lokal fortgeschrittener Basalzellkarzinome auf eine gleichzeitige Therapie mit Pembrolizumab und Sonidegib.
Published in:
Kompass Dermatologie, 2024, v. 12, n. 3, p. 188, doi. 10.1159/000539853
By:
- González-Cruz, Carlos;
- Muñoz-Couselo, Eva;
- Ortiz-Velez, Carolina;
- Ferrer, Berta;
- García-Patos, Vicente;
- Ferrándiz-Pulido, Carla
Publication type:
Article
NRAS-mutant melanoma: current challenges and future prospect.
Published in:
OncoTargets & Therapy, 2017, v. 10, p. 3941, doi. 10.2147/OTT.S117121
By:
- Muñoz-Couselo, Eva;
- Adelantado, Ester Zamora;
- Ortiz, Carolina;
- García, Jesús Soberino;
- Perez-Garcia, José
Publication type:
Article
Durable Response to Vemurafenib and Cobimetinib for the Treatment of BRAF-Mutated Metastatic Melanoma in Routine Clinical Practice.
Published in:
OncoTargets & Therapy, 2021, v. 14, p. 5345, doi. 10.2147/OTT.S325208
By:
- del Carmen Álamo, Mª;
- Ochenduszko, Sebastian;
- Crespo, Guillermo;
- Corral, Mónica;
- Oramas, Juana;
- Sancho, Pilar;
- Medina, Javier;
- Garicano, Fernando;
- López, Pedro;
- Balea, Begoña Campos;
- Garzotto, Analia Rodríguez;
- Muñoz-Couselo, Eva
Publication type:
Article
Current Perspectives and Novel Strategies of NRAS-Mutant Melanoma.
Published in:
OncoTargets & Therapy, 2021, v. 14, p. 3709, doi. 10.2147/OTT.S278095
By:
- Garcia-Alvarez, Alejandro;
- Ortiz, Carolina;
- Muñoz-Couselo, Eva
Publication type:
Article

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