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Effects of dendrimer/cyclodextrin conjugates as gene transfer carriers on nitric oxide production from macrophages.
Published in:
Journal of Pharmacy & Pharmacology, 2016, v. 68, n. 5, p. 598, doi. 10.1111/jphp.12439
By:
- Motoyama, Keiichi;
- Sako, Asumi;
- Ibrahim Abu Hashim, Irhan;
- Higashi, Taishi;
- Arima, Hidetoshi
Publication type:
Article
Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients.
Published in:
Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 8, p. 1133, doi. 10.1111/jphp.12405
By:
- Maeda, Yuki;
- Motoyama, Keiichi;
- Higashi, Taishi;
- Horikoshi, Yuka;
- Takeo, Toru;
- Nakagata, Naomi;
- Kurauchi, Yuki;
- Katsuki, Hiroshi;
- Ishitsuka, Yoichi;
- Kondo, Yuki;
- Irie, Tetsumi;
- Furuya, Hirokazu;
- Era, Takumi;
- Arima, Hidetoshi
Publication type:
Article
Hydroxypropyl-β-cyclodextrin Enhances Oral Absorption of Silymarin Nanoparticles Prepared Using PureNano™ Continuous Crystallizer.
Published in:
Pharmaceutics, 2022, v. 14, n. 2, p. 394, doi. 10.3390/pharmaceutics14020394
By:
- Onodera, Risako;
- Hayashi, Tomohiro;
- Motoyama, Keiichi;
- Tahara, Kohei;
- Takeuchi, Hirofumi
Publication type:
Article
Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for DNA, shRNA and siRNA.
Published in:
Pharmaceutics, 2012, v. 4, n. 1, p. 130, doi. 10.3390/pharmaceutics4010130
By:
- Arima, Hidetoshi;
- Motoyama, Keiichi;
- Higashi, Taishi
Publication type:
Article
Enhancement of α-Mangostin Wound Healing Ability by Complexation with 2-Hydroxypropyl-β-Cyclodextrin in Hydrogel Formulation.
Published in:
Pharmaceuticals (14248247), 2020, v. 13, n. 10, p. 290, doi. 10.3390/ph13100290
By:
- Wathoni, Nasrul;
- Sari, Diah Permata;
- Suharyani, Ine;
- Motoyama, Keiichi;
- Mohammed, Ahmed Fouad Abdelwahab;
- Cahyanto, Arief;
- Abdassah, Marline;
- Muchtaridi, Muchtaridi
Publication type:
Article
Potential Use of Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for siRNA.
Published in:
Pharmaceuticals (14248247), 2012, v. 5, n. 1, p. 61, doi. 10.3390/ph5010061
By:
- Arima, Hidetoshi;
- Motoyama, Keiichi;
- Higashi, Taishi
Publication type:
Article
Formulation and Characterization of α-Mangostin in Chitosan Nanoparticles Coated by Sodium Alginate, Sodium Silicate, and Polyethylene Glycol.
Published in:
Journal of Pharmacy & Bioallied Sciences, 2019, v. 11, p. S619, doi. 10.4103/jpbs.JPBS_206_19
By:
- Wathoni, Nasrul;
- Rusdin, Agus;
- Febriani, Erma;
- Purnama, Destiana;
- Daulay, Wahnidar;
- Azhary, Sundoro Y.;
- Panatarani, Camellia;
- Joni, I. Made;
- Lesmana, Ronny;
- Keiichi Motoyama;
- Muchtaridi, Muchtaridi
Publication type:
Article
Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann–Pick Disease Type C Model Mice.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 452, doi. 10.3390/ijms22010452
By:
- Fukaura, Madoka;
- Ishitsuka, Yoichi;
- Shirakawa, Seiichi;
- Ushihama, Naoki;
- Yamada, Yusei;
- Kondo, Yuki;
- Takeo, Toru;
- Nakagata, Naomi;
- Motoyama, Keiichi;
- Higashi, Taishi;
- Arima, Hidetoshi;
- Kurauchi, Yuki;
- Seki, Takahiro;
- Katsuki, Hiroshi;
- Higaki, Katsumi;
- Matsuo, Muneaki;
- Irie, Tetsumi
Publication type:
Article
Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in Npc1-Null Cells.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 3, p. 898, doi. 10.3390/ijms21030898
By:
- Hoque, Sanzana;
- Kondo, Yuki;
- Sakata, Nodoka;
- Yamada, Yusei;
- Fukaura, Madoka;
- Higashi, Taishi;
- Motoyama, Keiichi;
- Arima, Hidetoshi;
- Higaki, Katsumi;
- Hayashi, Akio;
- Komiya, Takaki;
- Ishitsuka, Yoichi;
- Irie, Tetsumi
Publication type:
Article
In Vitro and In Vivo Evaluation of 6-O-α-Maltosyl-β-Cyclodextrin as a Potential Therapeutic Agent Against Niemann-Pick Disease Type C.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 5, p. 1152, doi. 10.3390/ijms20051152
By:
- Yasmin, Nushrat;
- Ishitsuka, Yoichi;
- Fukaura, Madoka;
- Yamada, Yusei;
- Nakahara, Shuichi;
- Ishii, Akira;
- Kondo, Yuki;
- Takeo, Toru;
- Nakagata, Naomi;
- Motoyama, Keiichi;
- Higashi, Taishi;
- Okada, Yasuyo;
- Nishikawa, Junichi;
- Ichikawa, Atsushi;
- Iohara, Daisuke;
- Hirayama, Fumitoshi;
- Higaki, Katsumi;
- Ohno, Kousaku;
- Matsuo, Muneaki;
- Irie, Tetsumi
Publication type:
Article
Nusinersen improved respiratory function in spinal muscular atrophy type 2.
Published in:
Pediatrics International, 2021, v. 63, n. 8, p. 973, doi. 10.1111/ped.14510
By:
- Tanaka, Ryuta;
- Fukushima, Fujiko;
- Motoyama, Keiichi;
- Kobayashi, Chie;
- Izumi, Isho
Publication type:
Article
DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02619
By:
- Hayashi, Tomoya;
- Momota, Masatoshi;
- Kuroda, Etsushi;
- Kusakabe, Takato;
- Kobari, Shingo;
- Makisaka, Kotaro;
- Ohno, Yoshitaka;
- Suzuki, Yusuke;
- Nakagawa, Fumika;
- Lee, Michelle S. J.;
- Coban, Cevayir;
- Onodera, Risako;
- Higashi, Taishi;
- Motoyama, Keiichi;
- Ishii, Ken J.;
- Arima, Hidetoshi
Publication type:
Article
In Vitro and In Vivo Co-delivery of siRNA and Doxorubicin by Folate-PEG-Appended Dendrimer/Glucuronylglucosyl-β-Cyclodextrin Conjugate.
Published in:
AAPS Journal, 2019, v. 21, n. 4, p. N.PAG, doi. 10.1208/s12248-019-0327-9
By:
- Mohammed, Ahmed Fouad Abdelwahab;
- Higashi, Taishi;
- Motoyama, Keiichi;
- Ohyama, Ayumu;
- Onodera, Risako;
- Khaled, Khaled Ali;
- Sarhan, Hatem Abdelmonsef;
- Hussein, Amal Kamal;
- Arima, Hidetoshi
Publication type:
Article
Design and Evaluation of Thioalkylated Mannose-Modified Dendrimer (G3)/α-Cyclodextrin Conjugates as Antigen-Presenting Cell-Selective siRNA Carriers.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1298, doi. 10.1208/s12248-014-9665-9
By:
- Motoyama, Keiichi;
- Mitsuyasu, Ryosuke;
- Akao, Chiho;
- Tanaka, Takahiro;
- Ohyama, Ayumu;
- Sato, Nana;
- Higashi, Taishi;
- Arima, Hidetoshi
Publication type:
Article
2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141946
By:
- Yokoo, Masako;
- Kubota, Yasushi;
- Motoyama, Keiichi;
- Higashi, Taishi;
- Taniyoshi, Masatoshi;
- Tokumaru, Hiroko;
- Nishiyama, Rena;
- Tabe, Yoko;
- Mochinaga, Sakiko;
- Sato, Akemi;
- Sueoka-Aragane, Naoko;
- Sueoka, Eisaburo;
- Arima, Hidetoshi;
- Irie, Tetsumi;
- Kimura, Shinya
Publication type:
Article
Folic Acid-Appended Hydroxypropyl-β-Cyclodextrin Exhibits Potent Antitumor Activity in Chronic Myeloid Leukemia Cells via Autophagic Cell Death.
Published in:
Cancers, 2021, v. 13, n. 21, p. 5413, doi. 10.3390/cancers13215413
By:
- Hoshiko, Toshimi;
- Kubota, Yasushi;
- Onodera, Risako;
- Higashi, Taishi;
- Yokoo, Masako;
- Motoyama, Keiichi;
- Kimura, Shinya
Publication type:
Article
In Vitro Gene Delivery Mediated by Asialofetuin-Appended Cationic Liposomes Associated with γ-Cyclodextrin into Hepatocytes.
Published in:
Journal of Drug Delivery, 2011, p. 1, doi. 10.1155/2011/476137
By:
- Motoyama, Keiichi;
- Nakashima, Yoshihiro;
- Aramaki, Yukihiko;
- Hirayama, Fumitoshi;
- Uekama, Kaneto;
- Arima, Hidetoshi
Publication type:
Article
Effects of Selected Anionic β-Cyclodextrins on Persistence of Blood Glucose Lowering by Insulin Glargine after Subcutaneous Injection to Rats.
Published in:
Journal of Drug Delivery, 2011, p. 1, doi. 10.1155/2011/195146
By:
- Uehata, Keiko;
- Anno, Takayuki;
- Hayashida, Kayoko;
- Motoyama, Keiichi;
- Higashi, Taishi;
- Hirayama, Fumitoshi;
- Ono, Naomi;
- Pipkin, James D.;
- Uekama, Kaneto;
- Arima, Hidetoshi
Publication type:
Article
Control strategy and methods for continuous direct compression processes.
Published in:
Asian Journal of Pharmaceutical Sciences, 2021, v. 16, n. 2, p. 253, doi. 10.1016/j.ajps.2020.11.005
By:
- Yasuhiro Suzuki;
- Hirokazu Sugiyama;
- Manabu Kano;
- Ryutaro Shimono;
- Gosuke Shimada;
- Ryoichi Furukawa;
- Eichi Mano;
- Keiichi Motoyama;
- Tatsuo Koide;
- Yasuhiro Matsui;
- Kazuki Kurasaki;
- Issei Takayama;
- Shunin Hikage;
- Noriko Katori;
- Masahiko Kikuchi;
- Hiroshi Sakai;
- Yoshihiro Matsuda
Publication type:
Article
Induction of mitophagy-mediated antitumor activity with folate-appended methyl-β-cyclodextrin.
Published in:
International Journal of Nanomedicine, 2017, v. 12, p. 3433, doi. 10.2147/IJN.S133482
By:
- Kazuhisa Kameyama;
- Keiichi Motoyama;
- Nao Tanaka;
- Yuki Yamashita;
- Taishi Higashi;
- Hidetoshi Arima
Publication type:
Article
Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease type C treatment.
Published in:
Clinical & Translational Medicine, 2023, v. 13, n. 8, p. 1, doi. 10.1002/ctm2.1350
By:
- Yamada, Yusei;
- Fukaura‐Nishizawa, Madoka;
- Nishiyama, Asami;
- Ishii, Akira;
- Kawata, Tatsuya;
- Shirakawa, Aina;
- Tanaka, Mayuko;
- Kondo, Yuki;
- Takeo, Toru;
- Nakagata, Naomi;
- Miwa, Toru;
- Takeda, Hiroki;
- Orita, Yorihisa;
- Motoyama, Keiichi;
- Higashi, Taishi;
- Arima, Hidetoshi;
- Seki, Takahiro;
- Kurauchi, Yuki;
- Katsuki, Hiroshi;
- Higaki, Katsumi
Publication type:
Article
Recent Findings Concerning PAMAM Dendrimer Conjugates with Cyclodextrins as Carriers of DNA and RNA.
Published in:
Sensors (14248220), 2009, v. 9, n. 8, p. 6346, doi. 10.3390/s90806346
By:
- Arima, Hidetoshi;
- Motoyama, Keiichi
Publication type:
Article
One-pot synthesis of cyclodextrin-based radial poly[n]catenanes.
Published in:
Communications Chemistry, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42004-019-0180-x
By:
- Higashi, Taishi;
- Morita, Kentaro;
- Song, Xia;
- Zhu, Jingling;
- Tamura, Atsushi;
- Yui, Nobuhiko;
- Motoyama, Keiichi;
- Arima, Hidetoshi;
- Li, Jun
Publication type:
Article
Design Method Using Response Surface Model for CFRP Corrugated Structure under Quasistatic Crushing.
Published in:
Applied Sciences (2076-3417), 2021, v. 11, n. 21, p. 10178, doi. 10.3390/app112110178
By:
- Gomi, Tetsuya;
- Ayuzawa, Shotaro;
- Urushiyama, Yuta;
- Misaji, Kazuhito;
- Takahashi, Susumu;
- Motoyama, Keiichi;
- Suzuki, Kosuke
Publication type:
Article
Differential mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins increases safety margin in treatment of Niemann-Pick disease type C.
Published in:
2021
By:
- Yamada, Yusei;
- Ishitsuka, Yoichi;
- Kondo, Yuki;
- Nakahara, Shuichi;
- Nishiyama, Asami;
- Takeo, Toru;
- Nakagata, Naomi;
- Motoyama, Keiichi;
- Higashi, Taishi;
- Arima, Hidetoshi;
- Kamei, Shunsuke;
- Shuto, Tsuyoshi;
- Kai, Hirofumi;
- Hayashino, Yuji;
- Sugita, Masatake;
- Kikuchi, Takeshi;
- Hirata, Fumio;
- Miwa, Toru;
- Takeda, Hiroki;
- Orita, Yorihisa
Publication type:
journal article
The Potential Cytotoxic Activity Enhancement of α-Mangostin in Chitosan-Kappa Carrageenan-Loaded Nanoparticle against MCF-7 Cell Line.
Published in:
Polymers (20734360), 2021, v. 13, n. 11, p. 1681, doi. 10.3390/polym13111681
By:
- Wathoni, Nasrul;
- Meylina, Lisna;
- Rusdin, Agus;
- Mohammed, Ahmed Fouad Abdelwahab;
- Tirtamie, Dorandani;
- Herdiana, Yedi;
- Motoyama, Keiichi;
- Panatarani, Camelia;
- Joni, I Made;
- Lesmana, Ronny;
- Muchtaridi, Muchtaridi
Publication type:
Article
Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery System.
Published in:
Drug Design, Development & Therapy, 2020, v. 14, p. 4387, doi. 10.2147/DDDT.S273612
By:
- Wathoni, Nasrul;
- Nguyen, An Ny;
- Rusdin, Agus;
- Umar, Abd Kakhar;
- Mohammed, Ahmed Fouad Abdelwahab;
- Motoyama, Keiichi;
- Joni, I Made;
- Muchtaridi, Muchtaridi
Publication type:
Article
Involvement of Autophagy in Antitumor Activity of Folate-appended Methyl-β-cyclodextrin.
Published in:
Scientific Reports, 2014, p. 1, doi. 10.1038/srep04417
By:
- Risako Onodera;
- Keiichi Motoyama;
- Nao Tanaka;
- Ayumu Ohyama;
- Ayaka Okamatsu;
- Taishi Higashi;
- Ryusho Kariya;
- Seiji Okada;
- Hidetoshi Arima
Publication type:
Article
Design and Evaluation of the Highly Concentrated Human IgG Formulation Using Cyclodextrin Polypseudorotaxane Hydrogels.
Published in:
AAPS PharmSciTech, 2015, v. 16, n. 6, p. 1290, doi. 10.1208/s12249-015-0309-x
By:
- Higashi, Taishi;
- Tajima, Anna;
- Ohshita, Naoko;
- Hirotsu, Tatsunori;
- Hashim, Irhan;
- Motoyama, Keiichi;
- Koyama, Sawako;
- Iibuchi, Ruriko;
- Mieda, Shiuhei;
- Handa, Kenji;
- Kimoto, Tomoaki;
- Arima, Hidetoshi
Publication type:
Article
Nanoparticles of folic acid‐methyl‐β‐cyclodextrin (FA‐MβCD)/adamantane‐albumin exhibit enhanced antitumor activity compared with FA‐MβCD alone.
Published in:
FEBS Open Bio, 2023, v. 13, n. 2, p. 233, doi. 10.1002/2211-5463.13540
By:
- Sakai, Aiko;
- Yamashita, Yuki;
- Misumi, Shogo;
- Kishimoto, Naoki;
- Onodera, Risako;
- Higashi, Taishi;
- Arima, Hidetoshi;
- Motoyama, Keiichi
Publication type:
Article
Fasting impairs type 2 helper T cell infiltration in the lung of an eosinophilic asthma mouse model.
Published in:
FEBS Open Bio, 2021, v. 11, n. 9, p. 2619, doi. 10.1002/2211-5463.13268
By:
- Suzuki, Yusuke;
- Hayashi, Tomoya;
- Yokoyama, Ryoma;
- Nakagawa, Fumika;
- Inoue, Joe;
- Higashi, Taishi;
- Onodera, Risako;
- Motoyama, Keiichi
Publication type:
Article
Nanoparticle Drug Delivery Systems for α-Mangostin.
Published in:
Nanotechnology, Science & Applications, 2020, v. 13, p. 23, doi. 10.2147/NSA.S243017
By:
- Wathoni, Nasrul;
- Rusdin, Agus;
- Motoyama, Keiichi;
- Joni, I Made;
- Lesmana, Ronny;
- Muchtaridi, Muchtaridi
Publication type:
Article
Involvement of CD14 in the inhibitory effects of dimethyl-α-cyclodextrin on lipopolysaccharide signaling in macrophages
Published in:
FEBS Letters, 2005, v. 579, n. 7, p. 1707, doi. 10.1016/j.febslet.2005.01.076
By:
- Motoyama, Keiichi;
- Arima, Hidetoshi;
- Nishimoto, Yoji;
- Miyake, Kensuke;
- Hirayama, Fumitoshi;
- Uekama, Kaneto
Publication type:
Article
Folate-Appended Hydroxypropyl-β-Cyclodextrin Induces Autophagic Cell Death in Acute Myeloid Leukemia Cells.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16720, doi. 10.3390/ijms242316720
By:
- Kubota, Yasushi;
- Hoshiko, Toshimi;
- Higashi, Taishi;
- Motoyama, Keiichi;
- Okada, Seiji;
- Kimura, Shinya
Publication type:
Article
In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease.
Published in:
Nanomaterials (2079-4991), 2019, v. 9, n. 5, p. 802, doi. 10.3390/nano9050802
By:
- Maeda, Yuki;
- Motoyama, Keiichi;
- Nishiyama, Rena;
- Higashi, Taishi;
- Onodera, Risako;
- Nakamura, Hideaki;
- Takeo, Toru;
- Nakagata, Naomi;
- Yamada, Yusei;
- Ishitsuka, Yoichi;
- Kondo, Yuki;
- Irie, Tetsumi;
- Era, Takumi;
- Arima, Hidetoshi
Publication type:
Article

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