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Distinct spatiotemporal accumulation of N-truncated and full-length amyloid-β42 in Alzheimer's disease.
Published in:
2017
By:
- Mitsuru Shinohara;
- Shunsuke Koga;
- Takuya Konno;
- Nix, Jeremy;
- Motoko Shinohara;
- Naoya Aoki;
- Das, Pritam;
- Parisi, Joseph E.;
- Petersen, Ronald C.;
- Rosenberry, Terrone L.;
- Dickson, Dennis W.;
- Guojun Bu;
- Shinohara, Mitsuru;
- Koga, Shunsuke;
- Konno, Takuya;
- Shinohara, Motoko;
- Aoki, Naoya;
- Bu, Guojun
Publication type:
journal article
Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35227-z
By:
- Nakaya, Takeshi;
- Yabe, Miyuki;
- Mashalidis, Ellene H.;
- Sato, Toyotaka;
- Yamamoto, Kazuki;
- Hikiji, Yuta;
- Katsuyama, Akira;
- Shinohara, Motoko;
- Minato, Yusuke;
- Takahashi, Satoshi;
- Horiuchi, Motohiro;
- Yokota, Shin-ichi;
- Lee, Seok-Yong;
- Ichikawa, Satoshi
Publication type:
Article
Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression.
Published in:
2019
By:
- Yamazaki, Yu;
- Shinohara, Mitsuru;
- Shinohara, Motoko;
- Yamazaki, Akari;
- Murray, Melissa E;
- Liesinger, Amanda M;
- Heckman, Michael G;
- Lesser, Elizabeth R;
- Parisi, Joseph E;
- Petersen, Ronald C;
- Dickson, Dennis W;
- Kanekiyo, Takahisa;
- Bu, Guojun
Publication type:
journal article
5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 6, p. 1488, doi. 10.3390/ijms20061488
By:
- Zhao, Jing;
- Fu, Yuan;
- Liu, Chia-Chen;
- Shinohara, Motoko;
- Shinohara, Mitsuru;
- Kanekiyo, Takahisa;
- Bu, Guojun
Publication type:
Article
APOE2 is associated with longevity independent of Alzheimer's disease.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.62199
By:
- Mitsuru Shinohara;
- Takahisa Kanekiyo;
- Masaya Tachibana;
- Kurti, Aishe;
- Motoko Shinohara;
- Yuan Fu;
- Jing Zhao;
- Xianlin Han;
- Sullivan, Patrick M.;
- Rebeck, G. William;
- Fryer, John D.;
- Heckman, Michael G.;
- Guojun Bu
Publication type:
Article
Differential Regulation of Amyloid Precursor Protein/Presenilin 1 Interaction during Ab40/42 Production Detected Using Fusion Constructs.
Published in:
PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0048551
By:
- Sato, Naoyuki;
- Okochi, Masayasu;
- Shinohara, Mitsuru;
- Thinakaran, Gopal;
- Takeda, Shuko;
- Fukumori, Akio;
- Shinohara-Noma, Motoko;
- Mori-Ueda, Mari;
- Hamada, Hizuki;
- Takeda, Masatoshi;
- Rakugi, Hiromi;
- Morishita, Ryuichi
Publication type:
Article
Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes.
Published in:
FASEB Journal, 2020, v. 34, n. 2, p. 2425, doi. 10.1096/fj.201901028RR
By:
- Shinohara, Mitsuru;
- Tashiro, Yoshitaka;
- Shinohara, Motoko;
- Hirokawa, Junko;
- Suzuki, Kaoru;
- Onishi‐Takeya, Miyuki;
- Mukouzono, Masahiro;
- Takeda, Shuko;
- Saito, Takashi;
- Fukumori, Akio;
- Saido, Takaomi C.;
- Morishita, Ryuichi;
- Sato, Naoyuki
Publication type:
Article
APOE2 eases cognitive decline during Aging: Clinical and preclinical evaluations.
Published in:
2016
By:
- Shinohara, Mitsuru;
- Kanekiyo, Takahisa;
- Yang, Longyu;
- Linthicum, Duane;
- Shinohara, Motoko;
- Fu, Yuan;
- Price, Laura;
- Frisch ‐ Daiello, Jessica L.;
- Han, Xianlin;
- Fryer, John D.;
- Bu, Guojun;
- Frisch-Daiello, Jessica L
Publication type:
journal article
Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.
Published in:
Acta Neuropathologica, 2016, v. 132, n. 2, p. 225, doi. 10.1007/s00401-016-1580-y
By:
- Shinohara, Mitsuru;
- Murray, Melissa;
- Frank, Ryan;
- Shinohara, Motoko;
- DeTure, Michael;
- Yamazaki, Yu;
- Tachibana, Masaya;
- Atagi, Yuka;
- Davis, Mary;
- Liu, Chia-Chen;
- Zhao, Na;
- Painter, Meghan;
- Petersen, Ronald;
- Fryer, John;
- Crook, Julia;
- Dickson, Dennis;
- Bu, Guojun;
- Kanekiyo, Takahisa
Publication type:
Article
Neuronal Clearance of Amyloid-ß by Endocytic Receptor LRP1.
Published in:
Journal of Neuroscience, 2013, v. 33, n. 49, p. 19276, doi. 10.1523/JNEUROSCI.3487-13.2013
By:
- Takahisa Kanekiyo;
- Cirrito, John R.;
- Chia-Chen Liu;
- Shinohara, Mitsuru;
- Jie Li;
- Schuler, Dorothy R.;
- Motoko Shinohara;
- Holtzman, David M.;
- Guojun Bu
Publication type:
Article

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