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New Variants in the Enpp1 and Ptpn6 Genes Cause Low BMD, Crystal-Related Arthropathy, and Vascular Calcification.
Published in:
Journal of Bone & Mineral Research, 2009, v. 24, n. 9, p. 1552, doi. 10.1359/JBMR.090417
By:
- Babij, Philip;
- Roudier, Martine;
- Graves, Tom;
- Han, Chun-Ya E.;
- Chhoa, Mark;
- Chi-Ming Li;
- Juan, Todd;
- Morony, Sean;
- Grisanti, Mario;
- Xiaodong Li;
- Longchuan Yu;
- Dwyer, Denise;
- Lloyd, David J.;
- Bass, Michael B.;
- Richards, William G.;
- Ebeling, Christine;
- Amato, Julie;
- Carlson, George
Publication type:
Article
Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis.
Published in:
Journal of Bone & Mineral Research, 2009, v. 24, n. 4, p. 578, doi. 10.1359/jbmr.081206
By:
- Xiaodong Li;
- Ominsky, Michael S.;
- Warmington, Kelly S.;
- Morony, Sean;
- Gong, Jianhua;
- Jin Cao;
- Yongming Gao;
- Shalhoub, Victoria;
- Tipton, Barbara;
- Haldankar, Raj;
- Chen, Qing;
- Winters, Aaron;
- Boone, Tom;
- Zhaopo Geng;
- Niu, Qing-Tian;
- Hua Zhu Ke;
- Kostenuik, Paul J.;
- Simonet, W. Scott;
- Lacey, David L.;
- Paszty, Chris
Publication type:
Article
Denosumab, a Fully Human Monoclonal Antibody to RANKL, Inhibits Bone Resorption and Increases BMD in Knock-In Mice That Express Chimeric (Murine/Human) RANKL.
Published in:
Journal of Bone & Mineral Research, 2009, v. 24, n. 2, p. 182, doi. 10.1359/jbmr.081112
By:
- Kostenuik, Paul J.;
- Nguyen, Hung Q.;
- McCabe, James;
- Warmington, Kelly S.;
- Kurahara, Carol;
- Ning Sun;
- Ching Chen;
- Li, Luke;
- Cattley, Russ C.;
- Van, Gwyneth;
- Scully, Shelia;
- Elliott, Robin;
- Grisanti, Mario;
- Morony, Sean;
- Hong Lin Tan;
- Asuncion, Frank;
- Xiaodong Li;
- Ominsky, Michael S.;
- Stolina, Marina;
- Dwyer, Denise
Publication type:
Article
Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength.
Published in:
Journal of Bone & Mineral Research, 2008, v. 23, n. 6, p. 860, doi. 10.1359/jbmr.080216
By:
- Xiaodong Li;
- Ominsky, Michael S.;
- Qing-Tian Niu;
- Ning Sun;
- Daugherty, Betsy;
- D'Agostin, Diane;
- Kurahara, Carole;
- Yongming Gao;
- Jin Cao;
- Jianhua Gong;
- Asuncion, Frank;
- Barrero, Mauricio;
- Warmington, Kelly;
- Dwyer, Denise;
- Stolina, Marina;
- Morony, Sean;
- Sarosi, Ildiko;
- Kostenuik, Paul J.;
- Lacey, David L.;
- Simonet, W. Scott
Publication type:
Article
Infrequent Delivery of a Long-Acting PTH-Fc Fusion Protein Has Potent Anabolic Effects on Cortical and Cancellous Bone.
Published in:
Journal of Bone & Mineral Research, 2007, v. 22, n. 10, p. 1534, doi. 10.1359/JBMR.070616
By:
- Kostenuik, Paul J.;
- Ferrari, Serge;
- Pierroz, Dominique;
- Bouxsein, Mary;
- Morony, Sean;
- Warmington, Kelly S.;
- Adamu, Steven;
- Geng, Zhaopo;
- Grisanti, Mario;
- Shalhoub, Victoria;
- Martin, Steve;
- Biddlecome, Gloria;
- Shimamoto, Grant;
- Boone, Tom;
- Shen, Victor;
- Lacey, David
Publication type:
Article
Sustained Antiresorptive Effects After a Single Treatment With Human Recombinant Osteoprotegerin (OPG): A Pharmacodynamic and Pharmacokinetic Analysis in Rats.
Published in:
Journal of Bone & Mineral Research, 2003, v. 18, n. 5, p. 852, doi. 10.1359/jbmr.2003.18.5.852
By:
- Capparelli, Charles;
- Morony, Sean;
- Warmington, Kelly;
- Adamu, Stephen;
- Lacey, David;
- Dunstan, Colin R;
- Stouch, Brian;
- Martin, Steven;
- Kostenuik, Paul J
Publication type:
Article
A Chimeric Form of Osteoprotegerin Inhibits Hypercalcemia and Bone Resorption Induced by IL-1β, TNF-α, PTH, PTHrP, and 1,25(OH)<sub>2</sub>D<sub>3</sub>.
Published in:
Journal of Bone & Mineral Research, 1999, v. 14, n. 9, p. 1478, doi. 10.1359/jbmr.1999.14.9.1478
By:
- Morony, Sean;
- Capparelli, Casey;
- Lee, Richard;
- Shimamoto, Grant;
- Boone, Thomas;
- Lacey, David L.;
- Dunstan, Colin R.
Publication type:
Article
Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis.
Published in:
Clinical & Experimental Metastasis, 2008, v. 25, n. 2, p. 119, doi. 10.1007/s10585-007-9127-1
By:
- Canon, Jude;
- Roudier, Martine;
- Bryant, Rebecca;
- Morony, Sean;
- Stolina, Marina;
- Kostenuik, Paul;
- Dougall, William
Publication type:
Article
Bone Metastasis: Can osteoclasts be excluded? (Reply).
Published in:
2007
By:
- Jones, D. Holstead;
- Nakashima, Tomoki;
- Sanchez, Otto H.;
- Kozieradzki, Ivona;
- Komarova, Svetlana V.;
- Sarosi, Ildiko;
- Morony, Sean;
- Rubin, Evelyn;
- Sarao, Renu;
- Hojilla, Carlo V.;
- Komnenovic, Vukoslav;
- Young-Yun Kong;
- Schreiber, Martin;
- Dixon, S. Jeffrey;
- Sims, Stephen M.;
- Khokha, Rama;
- Wada, Teiji;
- Penninger, Josef M.
Publication type:
Letter
Regulation of cancer cell migration and bone metastasis by RANKL.
Published in:
Nature, 2006, v. 440, n. 7084, p. 692, doi. 10.1038/nature04524
By:
- Jones, D. Holstead;
- Nakashima, Tomoki;
- Sanchez, Otto H.;
- Kozieradzki, Ivona;
- Komarova, Svetlana V.;
- Sarosi, Ildiko;
- Morony, Sean;
- Rubin, Evelyn;
- Sarao, Renu;
- Hojilla, Carlo V.;
- Komnenovic, Vukoslav;
- Young-Yun Kong;
- Schreiber, Martin;
- Dixon, S. Jeffrey;
- Sims, Stephen M.;
- Khokha, Rama;
- Wada, Teiji;
- Penninger, Josef M.
Publication type:
Article
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand.
Published in:
Nature, 1999, v. 402, n. 6763, p. 43, doi. 10.1038/35005552
By:
- Kong, Young-Yun;
- Feige, Ulrich;
- Sarosi, Iidiko;
- Bolon, Brad;
- Tafuri, Anna;
- Morony, Sean;
- Capparelli, Casey;
- Li, Ji;
- Elliott, Robin;
- McCabe, Susan;
- Wong, Thomas;
- Campagnuolo, Giuseppe;
- Moran, Erika;
- Bogoch, Earl R.;
- Van, Gwyneth;
- Nguyen, Linh T.;
- Ohashi, Pamela S.;
- Lacey, David L.;
- Fish, Eleanor
Publication type:
Article
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis.
Published in:
Nature, 1999, v. 397, n. 6717, p. 315, doi. 10.1038/16852
By:
- Kong, Young-Yun;
- Yoshida, Hiroki;
- Sarosi, Ildiko;
- Hong-Lin Tan;
- Timms, Emma;
- Capparelli, Casey;
- Morony, Sean;
- Oliveira-dos-Santos, Antonio J.;
- Van, Gwyneth;
- Itie, Annick;
- Khoo, Wilson;
- Wakeham, Andrew;
- Dunstan, Colin R.;
- Lacey, David L.;
- Mak, Tak W.;
- Boyle, William J.;
- Penninger, Josef M.
Publication type:
Article

Found: 12