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A novel sustained-release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers.
Published in:
Pharmacology Research & Perspectives, 2021, v. 9, n. 2, p. 1, doi. 10.1002/prp2.739
By:
- Berends, Cécile L.;
- Pagan, Lisa;
- van Esdonk, Michiel J.;
- Klarenbeek, Naomi B.;
- Bergmann, Kirsten R.;
- Moerland, Matthijs;
- der Wel, Vincent van;
- de Visser, Saco J.;
- Büller, Hans;
- Loos, Frans de;
- de Vries, Wouter S.;
- Waals, Hans;
- de Leede, Leo G. J.;
- Burggraaf, Jacobus;
- Kamerling, Ingrid M. C.
Publication type:
Article
Novel SGLT2 inhibitor: first-in-man studies of antisense compound is associated with unexpected renal effects.
Published in:
Pharmacology Research & Perspectives, 2017, v. 5, n. 1, p. n/a, doi. 10.1002/prp2.292
By:
- Meer, Leonie;
- Dongen, Marloes;
- Moerland, Matthijs;
- Kam, Marieke;
- Cohen, Adam;
- Burggraaf, Jacobus
Publication type:
Article
Immune Monitoring of Mycophenolate Mofetil Activity in Healthy Volunteers Using Ex Vivo T Cell Function Assays.
Published in:
Pharmaceutics, 2023, v. 15, n. 6, p. 1635, doi. 10.3390/pharmaceutics15061635
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- de Kam, Marieke L.;
- Yavuz, Yalҫin;
- Moes, Dirk Jan A. R.;
- Oudhoff, Kathalijne A.;
- van Poelgeest, Mariette I. E.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
Monitoring of Ex Vivo Cyclosporin a Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics.
Published in:
Pharmaceutics, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/pharmaceutics14091958
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Huisman, Bertine W.;
- Schoonakker, Mascha;
- de Kam, Marieke L.;
- Moes, Dirk Jan A. R.;
- van Poelgeest, Mariëtte I. E.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4710, doi. 10.3390/ijms20194710
By:
- in 't Veld, Aliede E.;
- Grievink, Hendrika W.;
- Saghari, Mahdi;
- Stuurman, Frederik E.;
- de Kam, Marieke L.;
- de Vries, Aiko P. J.;
- de Winter, Brenda C. M.;
- Burggraaf, Jacobus;
- Cohen, Adam F.;
- Moerland, Matthijs
Publication type:
Article
Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island.
Published in:
BMC Developmental Biology, 2007, v. 7, p. 108, doi. 10.1186/1471-213X-7-108
By:
- Katsantoni, Eleni Z.;
- Anghelescu, Nora E.;
- Rottier, Robbert;
- Moerland, Matthijs;
- Antoniou, Michael;
- de Crom, Rini;
- Grosveld, Frank;
- Strouboulis, John
Publication type:
Article
Lack of a clinically relevant effect of sugammadex on anti-Xa activity or activated partial thromboplastin time following pretreatment with either unfractionated or low-molecular-weight heparin in healthy subjects.
Published in:
International Journal of Clinical Pharmacology & Therapeutics, 2014, v. 52, n. 8, p. 631, doi. 10.5414/CP202091
By:
- De Kam, Pieter-Jan;
- Kruithof, Annelieke C.;
- van Lierop, Marie-José;
- Moerland, Matthijs;
- Dennie, Justin;
- Troyer, Matthew D.;
- Langdon, Ronald B.;
- Gutstein, David E.;
- Burggraaf, Jacobus;
- El Galta, Rachid
Publication type:
Article
No clinically relevant interaction between sugammadex and aspirin on platelet aggregation and coagulation parameters.
Published in:
International Journal of Clinical Pharmacology & Therapeutics, 2013, v. 51, n. 12, p. 976, doi. 10.5414/CP201970
By:
- de Kam, Pieter-Jan;
- Galta, Rachid El;
- Kruithof, Annelieke C.;
- Fennema, Hein;
- van Lierop, Marie-José;
- Mihara, Katsuhiro;
- Burggraaf, Jacobus;
- Moerland, Matthijs;
- Peeters, Pierre;
- Troyer, Matthew D.
Publication type:
Article
Immunomodulating effects of the single bacterial strain therapy EDP1815 on innate and adaptive immune challenge responses — a randomized, placebo-controlled clinical trial.
Published in:
Immunologic Research, 2024, v. 72, n. 4, p. 776, doi. 10.1007/s12026-024-09484-7
By:
- Eveleens Maarse, Boukje C.;
- Ronner, Micha N.;
- Jansen, Manon A. A.;
- Niemeyer-van der Kolk, Tessa;
- in 't Veld, Aliede E.;
- Klaassen, Erica S.;
- Ahmad, Saira;
- Itano, Andrea;
- McHale, Duncan;
- Moerland, Matthijs
Publication type:
Article
Immunosuppression by hydroxychloroquine: mechanistic proof in in vitro experiments but limited systemic activity in a randomized placebo-controlled clinical pharmacology study.
Published in:
Immunologic Research, 2023, v. 71, n. 4, p. 617, doi. 10.1007/s12026-023-09367-3
By:
- in 't Veld, Aliede E.;
- Grievink, Hendrika W.;
- van der Plas, Johan L.;
- Eveleens Maarse, Boukje C.;
- van Kraaij, Sebastiaan J. W.;
- Woutman, Tess D.;
- Schoonakker, Mascha;
- Klarenbeek, Naomi B.;
- de Kam, Marieke L.;
- Kamerling, Ingrid M. C.;
- Jansen, Manon A. A.;
- Moerland, Matthijs
Publication type:
Article
Elevated Expression of Phospholipid Transfer Protein in Bone Marrow Derived Cells Causes Atherosclerosis.
Published in:
PLoS ONE, 2008, v. 3, n. 5, p. 1, doi. 10.1371/journal.pone.0002255
By:
- van Haperen, Rien;
- Samyn, Hannelore;
- Moerland, Matthijs;
- van Gent, Teus;
- Peeters, Marian;
- Grosveld, Frank;
- van Tol, Arie;
- de Crom, Rini
Publication type:
Article
Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19.
Published in:
2021
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Ciere, Luuk C. A.;
- Moerland, Matthijs
Publication type:
journal article
Erratum to "Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19".
Published in:
2021
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Ciere, Luuk C. A.;
- Moerland, Matthijs
Publication type:
corrected article
Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19.
Published in:
Journal of Immunology Research, 2021, p. 1, doi. 10.1155/2021/6659410
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Ciere, Luuk C. A.;
- Moerland, Matthijs
Publication type:
Article
A phase 1 trial of AP30663, a K<sub>Ca</sub>2 channel inhibitor in development for conversion of atrial fibrillation.
Published in:
British Journal of Clinical Pharmacology, 2024, v. 90, n. 4, p. 1027, doi. 10.1111/bcp.15973
By:
- Yfanti, Christina;
- Vestbjerg, Birgitte;
- van't Westende, Juliette;
- Edvardsson, Nils;
- Monfort, Laia Meseguer;
- Olesen, Morten Salling;
- Bentzen, Bo Hjorth;
- Grunnet, Morten;
- Eveleens Maarse, Boukje C.;
- Diness, Jonas Goldin;
- Kemme, Michiel J. B.;
- Sørensen, Ulrik;
- Moerland, Matthijs;
- van Esdonk, Michiel J.;
- Klaassen, Erica S.;
- Gal, Pim;
- Holst, Anders G.
Publication type:
Article
Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 5420, doi. 10.1111/bcp.15476
By:
- Liu, Feiyan;
- Aulin, Linda B. S.;
- Guo, Tingjie;
- Krekels, Elke H. J.;
- Moerland, Matthijs;
- van der Graaf, Piet H.;
- van Hasselt, Johan G. C.
Publication type:
Article
Effect of hydroxychloroquine on the cardiac ventricular repolarization: A randomized clinical trial.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 3, p. 1054, doi. 10.1111/bcp.15013
By:
- Eveleens Maarse, Boukje C.;
- Graff, Claus;
- Kanters, Jørgen K.;
- van Esdonk, Michiel J.;
- Kemme, Michiel J. B.;
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Moerland, Matthijs;
- Gal, Pim
Publication type:
Article
Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 2, p. 680, doi. 10.1111/bcp.14999
By:
- Buters, Thomas P.;
- Hameeteman, Pieter W.;
- Jansen, Iris M. E.;
- van Hindevoort, Floris C.;
- ten Voorde, Wouter;
- Florencia, Edwin;
- Osse, Michelle;
- de Kam, Marieke L.;
- Grievink, Hendrika W.;
- Schoonakker, Mascha;
- Patel, Amit A.;
- Yona, Simon;
- Gilroy, Derek W.;
- Lubberts, Erik;
- Damman, Jeffrey;
- Feiss, Gary;
- Rissmann, Robert;
- Jansen, Manon A. A.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
A randomized single and multiple ascending dose study in healthy volunteers of LTI‐291, a centrally penetrant glucocerebrosidase activator.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 9, p. 3561, doi. 10.1111/bcp.14772
By:
- den Heijer, Jonas M.;
- Kruithof, Annelieke C.;
- van Amerongen, Guido;
- de Kam, Marieke L.;
- Thijssen, Eva;
- Grievink, Hendrika W.;
- Moerland, Matthijs;
- Walker, Mike;
- Been, Kees;
- Skerlj, Renato;
- Justman, Craig;
- Dudgeon, Lindsay;
- Lansbury, Peter;
- Cullen, Valerie C.;
- Hilt, Dana C.;
- Groeneveld, Geert Jan
Publication type:
Article
Comprehensive evaluation of microneedle‐based intradermal adalimumab delivery vs. subcutaneous administration: results of a randomized controlled clinical trial.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 8, p. 3162, doi. 10.1111/bcp.14729
By:
- Jacobse, Justin;
- Voorde, Wouter;
- Tandon, Anushka;
- Romeijn, Stefan G.;
- Grievink, Hendrika W.;
- Maaden, Koen;
- Esdonk, Michiel J.;
- Moes, Dirk Jan A.R.;
- Loeff, Floris;
- Bloem, Karien;
- Vries, Annick;
- Rispens, Theo;
- Wolbink, Gertjan;
- Kam, Marieke;
- Ziagkos, Dimitrios;
- Moerland, Matthijs;
- Jiskoot, Wim;
- Bouwstra, Joke;
- Burggraaf, Jacobus;
- Schrier, Lenneke
Publication type:
Article
Safety, pharmacokinetics and pharmacodynamics of SBT‐020 in patients with early stage Huntington's disease, a 2‐part study.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 5, p. 2290, doi. 10.1111/bcp.14656
By:
- Diemen, Marcus P.J.;
- Hart, Ellen P.;
- Abbruscato, Anthony;
- Mead, Liz;
- Beelen, Ilse;
- Bergheanu, Sandrin C.;
- Hameeteman, Pieter W.;
- Coppen, Emma;
- Winder, Jessica Y.;
- Moerland, Matthijs;
- Kan, Hermien;
- Grond, Jeroen;
- Webb, Andrew;
- Roos, Raymund A.C.;
- Groeneveld, Geert Jan
Publication type:
Article
Proof of pharmacology of Org 48775‐0, a p38 MAP kinase inhibitor, in healthy volunteers.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 5, p. 2321, doi. 10.1111/bcp.14655
By:
- Moerland, Matthijs;
- Kales, Andrea J.;
- Broekhuizen, Karen;
- Nässander, Ulla;
- Nelissen, Rob;
- Kam, Marieke L.;
- Peeters, Pierre A.M.;
- Burggraaf, Jacobus
Publication type:
Article
A randomized controlled trial with a delayed‐type hypersensitivity model using keyhole limpet haemocyanin to evaluate adaptive immune responses in man.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 4, p. 1953, doi. 10.1111/bcp.14588
By:
- Saghari, Mahdi;
- Gal, Pim;
- Ziagkos, Dimitrios;
- Burggraaf, Jacobus;
- Powell, John F.;
- Brennan, Nuala;
- Rissmann, Robert;
- Doorn, Martijn B.A.;
- Moerland, Matthijs
Publication type:
Article
Blueprint for mechanistic, data‐rich early phase clinical pharmacology studies in dermatology.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 6, p. 1011, doi. 10.1111/bcp.14293
By:
- Rissmann, Robert;
- Moerland, Matthijs;
- Doorn, Martijn B.A.
Publication type:
Article
Adverse immunostimulation caused by impurities: The dark side of biopharmaceuticals.
Published in:
British Journal of Clinical Pharmacology, 2019, v. 85, n. 7, p. 1418, doi. 10.1111/bcp.13938
By:
- Reijers, Joannes A. A.;
- Malone, Karen E.;
- Bajramovic, Jeffrey J.;
- Verbeek, Richard;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
Injection site reactions after subcutaneous oligonucleotide therapy.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 82, n. 2, p. 340, doi. 10.1111/bcp.12961
By:
- Meer, Leonie;
- Moerland, Matthijs;
- Gallagher, Jolie;
- Doorn, Martijn B. A.;
- Prens, Errol P.;
- Cohen, Adam F.;
- Rissmann, Robert;
- Burggraaf, Jacobus
Publication type:
Article
Antisense-mediated reduction of proprotein convertase subtilisin/kexin type 9 (PCSK9): a firstin- human randomized, placebo-controlled trial.
Published in:
British Journal of Clinical Pharmacology, 2015, v. 80, n. 6, p. 1350, doi. 10.1111/bcp.12738
By:
- Poelgeest, Eveline P.;
- Hodges, Michael R.;
- Moerland, Matthijs;
- Tessier, Yann;
- Levin, Arthur A.;
- Persson, Robert;
- Lindholm, Marie W.;
- Dumong Erichsen, Kamille;
- Ørum, Henrik;
- Cohen, Adam F.;
- Burggraaf, Jacobus
Publication type:
Article
Urinary kidney biomarkers for early detection of nephrotoxicity in clinical drug development.
Published in:
British Journal of Clinical Pharmacology, 2014, v. 77, n. 6, p. 947, doi. 10.1111/bcp.12282
By:
- Meer, Leonie;
- Moerland, Matthijs;
- Cohen, Adam F.;
- Burggraaf, Jacobus
Publication type:
Article
A multimodal, comprehensive characterization of a cutaneous wound model in healthy volunteers.
Published in:
Experimental Dermatology, 2023, v. 32, n. 7, p. 1028, doi. 10.1111/exd.14808
By:
- ten Voorde, Wouter;
- Saghari, Mahdi;
- Boltjes, Jiry;
- de Kam, Marieke L.;
- Zhuparris, Ahnjili;
- Feiss, Gary;
- Buters, Thomas P.;
- Prens, Errol P.;
- Damman, Jeffrey;
- Niemeyer‐van der Kolk, Tessa;
- Moerland, Matthijs;
- Burggraaf, Jacobus;
- van Doorn, Martijn B. A.;
- Rissmann, Robert
Publication type:
Article
Oral prednisolone suppresses skin inflammation in a healthy volunteer imiquimod challenge model.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1197650
By:
- Assil, Salma;
- Buters, Thomas P.;
- Hameeteman, Pieter W.;
- Hallard, Charlie;
- Treijtel, Nicoline;
- Niemeyer - Van der Kolk, Tessa;
- de Kam, Marieke L.;
- Florencia, Edwin F. I. I. I.;
- Prens, Errol P.;
- van Doorn, Martijn B. A.;
- Rissmann, Robert;
- Klarenbeek, Naomi B.;
- Jansen, Manon A. A.;
- Moerland, Matthijs
Publication type:
Article
Additive effect of erythropoietin use on exercise-induced endothelial activation and hypercoagulability in athletes.
Published in:
2020
By:
- Heuberger, Jules A. A. C.;
- Posthuma, Jelle J.;
- Ziagkos, Dimitrios;
- Rotmans, Joris I.;
- Daniels, Johannes M. A.;
- Gal, Pim;
- Stuurman, Frederik E.;
- Spronk, Henri M. H.;
- Ten Cate, Hugo;
- Burggraaf, Jacobus;
- Moerland, Matthijs;
- Cohen, Adam F.
Publication type:
journal article
OX40L Inhibition Suppresses KLH‐driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof‐of‐Pharmacology for KY1005.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1121, doi. 10.1002/cpt.2539
By:
- Saghari, Mahdi;
- Gal, Pim;
- Gilbert, Sally;
- Yateman, Martin;
- Porter‐Brown, Ben;
- Brennan, Nuala;
- Quaratino, Sonia;
- Wilson, Rosamund;
- Grievink, Hendrika W.;
- Klaassen, Erica S.;
- Bergmann, Kirsten R.;
- Burggraaf, Jacobus;
- van Doorn, Martijn B. A.;
- Powell, John;
- Moerland, Matthijs;
- Rissmann, Robert
Publication type:
Article
Clinical, Cellular, and Molecular Effects of Corticosteroids on the Response to Intradermal Lipopolysaccharide Administration in Healthy Volunteers.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 964, doi. 10.1002/cpt.2516
By:
- Buters, Thomas P.;
- Hameeteman, Pieter W.;
- Jansen, Iris M.E.;
- van Hindevoort, Floris C.;
- ten Voorde, Wouter;
- Grievink, Hendrika W.;
- Schoonakker, Mascha;
- de Kam, Marieke L.;
- Gilroy, Derek W.;
- Feiss, Gary;
- Rissmann, Robert;
- Jansen, Manon A.A.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
DNL104, a Centrally Penetrant RIPK1 Inhibitor, Inhibits RIP1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers.
Published in:
Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 2, p. 406, doi. 10.1002/cpt.1615
By:
- Grievink, Hendrika W.;
- Heuberger, Jules A.A.C.;
- Huang, Fen;
- Chaudhary, Rinkal;
- Birkhoff, Willem A.J.;
- Tonn, George R.;
- Mosesova, Sofia;
- Erickson, Rebecca;
- Moerland, Matthijs;
- Haddick, Patrick C.G.;
- Scearce‐Levie, Kimberly;
- Ho, Carole;
- Groeneveld, Geert Jan
Publication type:
Article
Intersubject and Intrasubject Variability of Potential Plasma and Urine Metabolite and Protein Biomarkers in Healthy Human Volunteers.
Published in:
Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 2, p. 397, doi. 10.1002/cpt.1606
By:
- Duisters, Kevin;
- Ogino, Shinji;
- Andou, Tomohiro;
- Ito, Kazumi;
- Akabane, Takafumi;
- Harms, Amy;
- Moerland, Matthijs;
- Hashimoto, Yuka;
- Ando, Ayumi;
- Ohtsu, Yoshiaki;
- Wada, Naoya;
- Yukinaga, Hideo;
- Meulman, Jacqueline;
- Kobayashi, Hiroyuki;
- Kobayashi, Nobuhiro;
- Suzumura, Kenichi;
- Hankemeier, Thomas
Publication type:
Article
The Effect of a 13-Valent Conjugate Pneumococcal Vaccine on Circulating Antibodies Against Oxidized LDL and Phosphorylcholine in Man, A Randomized Placebo-Controlled Clinical Trial.
Published in:
Biology (2079-7737), 2020, v. 9, n. 11, p. 345, doi. 10.3390/biology9110345
By:
- Grievink, Hendrika W.;
- Gal, Pim;
- Ozsvar Kozma, Maria;
- Klaassen, Erica S.;
- Kuiper, Johan;
- Burggraaf, Jacobus;
- Binder, Christoph J.;
- Moerland, Matthijs
Publication type:
Article
Clinical Evaluation of Humira® Biosimilar Ons-3010 in Healthy Volunteers: Focus on Pharmacokinetics and Pharmacodynamics.
Published in:
Frontiers in Immunology, 2016, v. 7, p. 1, doi. 10.3389/fimmu.2016.00508
By:
- Dillingh, Marlous R.;
- Reijers, Joannes A. A.;
- Malone, Karen E.;
- Burggraaf, Jacobus;
- Bahrt, Kenneth;
- Yamashita, Liz;
- Rehrig, Claudia;
- Moerland, Matthijs
Publication type:
Article
A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis.
Published in:
Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 6, p. 645, doi. 10.1007/s10928-022-09828-6
By:
- Liu, Feiyan;
- Aulin, Linda B. S.;
- Kossen, Sebastiaan S. A.;
- Cathalina, Julius;
- Bremmer, Marlotte;
- Foks, Amanda C.;
- van der Graaf, Piet H.;
- Moerland, Matthijs;
- van Hasselt, Johan G. C.
Publication type:
Article
A Phase 1B Trial in GBA1‐Associated Parkinson's Disease of BIA‐28‐6156, a Glucocerebrosidase Activator.
Published in:
Movement Disorders, 2023, v. 38, n. 7, p. 1197, doi. 10.1002/mds.29346
By:
- den Heijer, Jonas M.;
- Kruithof, Annelieke C.;
- Moerland, Matthijs;
- Walker, Mike;
- Dudgeon, Lindsay;
- Justman, Craig;
- Solomini, Imelda;
- Splitalny, Leslie;
- Leymarie, Nancy;
- Khatri, Kshitij;
- Cullen, Valerie C.;
- Hilt, Dana C.;
- Groeneveld, Geert Jan;
- Lansbury, Peter
Publication type:
Article
A Biomarker Study in Patients with GBA1‐Parkinson's Disease and Healthy Controls.
Published in:
Movement Disorders, 2023, v. 38, n. 5, p. 783, doi. 10.1002/mds.29360
By:
- den Heijer, Jonas M.;
- Cullen, Valerie C.;
- Pereira, Diana R.;
- Yavuz, Yalcin;
- de Kam, Marieke L.;
- Grievink, Hendrika W.;
- Moerland, Matthijs;
- Leymarie, Nancy;
- Khatri, Kshitij;
- Sollomoni, Imelda;
- Spitalny, Leslie;
- Dungeon, Lindsay;
- Hilt, Dana C.;
- Justman, Craig;
- Lansbury, Peter;
- Groeneveld, Geert Jan
Publication type:
Article
A Randomized First‐in‐Human Study With UB‐312, a UBITh® α‐Synuclein Peptide Vaccine.
Published in:
Movement Disorders, 2022, v. 37, n. 7, p. 1416, doi. 10.1002/mds.29016
By:
- Yu, Hui Jing;
- Thijssen, Eva;
- van Brummelen, Emilie;
- van der Plas, Johan L.;
- Radanovic, Igor;
- Moerland, Matthijs;
- Hsieh, Eric;
- Groeneveld, Geert Jan;
- Dodart, Jean‐Cosme
Publication type:
Article
Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia.
Published in:
Inflammation Research, 2022, v. 71, n. 9, p. 999, doi. 10.1007/s00011-022-01610-1
By:
- Aulin, Linda B. S.;
- Kleijburg, Anne;
- Moerland, Matthijs;
- van Hasselt, J. G. Coen
Publication type:
Article
Open-Label Interventional Study in Healthy Volunteers to Evaluate NO-Mediated Vasodilation by Dermal Allyl Isothiocyanate Challenge and Whole-Body Heat Stress.
Published in:
Journal of Experimental Pharmacology, 2024, v. 16, p. 285, doi. 10.2147/JEP.S473217
By:
- van Ruissen, Marella CE;
- van Kraaij, Sebastiaan JW;
- Gal, Pim;
- Bakker, Wouter A;
- Hijma, Hemme J;
- Groeneveld, Geert Jan;
- de Kam, Marieke L;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
Remarkable Pharmacokinetics of Monoclonal Antibodies: A Quest for an Explanation.
Published in:
2017
By:
- Reijers, Joannes;
- Moerland, Matthijs;
- Burggraaf, Jacobus;
- Reijers, Joannes A A
Publication type:
journal article
Immune responsiveness in stable kidney transplantation patients: Complete inhibition of T‐cell proliferation but residual T‐cell activity during maintenance immunosuppressive treatment.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 6, p. 1, doi. 10.1111/cts.13860
By:
- in 't Veld, Aliede E.;
- Eveleens Maarse, Boukje C.;
- Juachon, Maria J.;
- Meziyerh, Soufian;
- de Vries, Aiko P. J.;
- van Rijn, Aline L.;
- Feltkamp, Mariet C. W.;
- Moes, Dirk Jan A. R.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
The oral IRAK4 inhibitors zabedosertib and BAY1830839 suppress local and systemic immune responses in a randomized trial in healthy male volunteers.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13771
By:
- Jodl, Stefan J.;
- ten Voorde, Wouter;
- Klein, Stefan;
- Wagenfeld, Andrea;
- Zollmann, Frank S.;
- Feldmüller, Maximilian;
- Klarenbeek, Naomi B.;
- de Bruin, Digna T.;
- Jansen, Manon A. A.;
- Rissmann, Robert;
- Rohde, Beate;
- Moerland, Matthijs
Publication type:
Article
Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease.
Published in:
CTS: Clinical & Translational Science, 2023, v. 16, n. 7, p. 1258, doi. 10.1111/cts.13530
By:
- van Kraaij, Sebastiaan J. W.;
- Pereira, Diana R.;
- Smal, Bastiaan;
- Summo, Luciana;
- Konkel, Anne;
- Lossie, Janine;
- Busjahn, Andreas;
- Grammatopoulos, Tom N.;
- Klaassen, Erica;
- Fischer, Robert;
- Schunck, Wolf‐Hagen;
- Gal, Pim;
- Moerland, Matthijs
Publication type:
Article
Antimicrobial Peptide Omiganan Enhances Interferon Responses to Endosomal Toll‐Like Receptor Ligands in Human Peripheral Blood Mononuclear Cells.
Published in:
CTS: Clinical & Translational Science, 2020, v. 13, n. 5, p. 891, doi. 10.1111/cts.12789
By:
- Grievink, Hendrika W.;
- Jirka, Silvana M. G.;
- Woutman, Tess D.;
- Schoonakker, Mascha;
- Rissmann, Robert;
- Malone, Karen E.;
- Feiss, Gary;
- Moerland, Matthijs
Publication type:
Article
Omiganan Enhances Imiquimod‐Induced Inflammatory Responses in Skin of Healthy Volunteers.
Published in:
CTS: Clinical & Translational Science, 2020, v. 13, n. 3, p. 573, doi. 10.1111/cts.12741
By:
- Niemeyer‐van der Kolk, Tessa;
- Assil, Salma;
- Buters, Thomas P.;
- Rijsbergen, Melanie;
- Klaassen, Erica S.;
- Feiss, Gary;
- Florencia, Edwin;
- Prens, Errol P.;
- Burggraaf, Jacobus;
- Doorn, Martijn B.A.;
- Rissmann, Robert;
- Moerland, Matthijs
Publication type:
Article
Comprehensive, Multimodal Characterization of an Imiquimod‐Induced Human Skin Inflammation Model for Drug Development.
Published in:
CTS: Clinical & Translational Science, 2018, v. 11, n. 6, p. 607, doi. 10.1111/cts.12563
By:
- der Kolk, Tessa;
- Assil, Salma;
- Rijneveld, Rianne;
- Klaassen, Erica S.;
- Feiss, Gary;
- Florencia, Edwin;
- Prens, Errol P.;
- Burggraaf, Jacobus;
- Moerland, Matthijs;
- Rissmann, Robert;
- Doorn, Martijn B.A.
Publication type:
Article

Found: 57