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Treating Systemic Klotho Deficiency.
Published in:
2019
By:
- Pastor, Johanne;
- Moe, Orson W.;
- Moe, Orson W
Publication type:
Editorial
Bone Dysregulation in Acute Kidney Injury.
Published in:
Nephron, 2023, v. 147, n. 12, p. 747, doi. 10.1159/000534228
By:
- Neyra, Javier A.;
- Moe, Orson W.
Publication type:
Article
Parathyroid Hormone and Plasma Phosphate Are Predictors of Soluble α-Klotho Levels in Adults of European Descent.
Published in:
2019
By:
- Dhayat, Nasser A;
- Pruijm, Menno;
- Ponte, Belen;
- Ackermann, Daniel;
- Leichtle, Alexander Benedikt;
- Devuyst, Olivier;
- Ehret, Georg;
- Guessous, Idris;
- Pechère-Bertschi, Antoinette;
- Pastor, Johanne;
- Martin, Pierre-Yves;
- Burnier, Michel;
- Fiedler, Georg-Martin;
- Vogt, Bruno;
- Moe, Orson W;
- Bochud, Murielle;
- Fuster, Daniel G
Publication type:
journal article
Fibroblast growth factor 23: friend or foe in uremia?
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 7, p. 2354, doi. 10.1172/JCI64184
By:
- Moe, Orson W.
Publication type:
Article
When EGF is offside, magnesium is wasted.
Published in:
2007
By:
- Muallem, Shmuel;
- Moe, Orson W.
Publication type:
journal article
Strategies to lower fibroblast growth factor 23 bioactivity.
Published in:
Nephrology Dialysis Transplantation, 2022, v. 37, n. 10, p. 1800, doi. 10.1093/ndt/gfab012
By:
- Verbueken, Devin;
- Moe, Orson W
Publication type:
Article
Assessment of a modified renal angina index for AKI prediction in critically ill adults.
Published in:
Nephrology Dialysis Transplantation, 2022, v. 37, n. 5, p. 895, doi. 10.1093/ndt/gfab049
By:
- Ortiz-Soriano, Victor;
- Kabir, Shaowli;
- Granado, Rolando Claure-Del;
- Stromberg, Arnold;
- Toto, Robert D;
- Moe, Orson W;
- Goldstein, Stuart L;
- Neyra, Javier A
Publication type:
Article
In search of alternatively spliced alpha‐Klotho Kl1 protein in mouse brain.
Published in:
FASEB Bioadvances, 2021, v. 3, n. 7, p. 531, doi. 10.1096/fba.2020-00066
By:
- Li, Liping;
- Pastor, Johanne;
- Zhang, Jianning;
- Davidson, Taylor;
- Hu, Ming‐Chang;
- Moe, Orson W.
Publication type:
Article
Alpha‐Klotho, a critical protein for lung health, is not expressed in normal lung.
Published in:
FASEB Bioadvances, 2019, v. 1, n. 11, p. 675, doi. 10.1096/fba.2019-00016
By:
- Zhang, Jianning;
- Cao, Khoa;
- Pastor, Johanne V.;
- Li, Liping;
- Moe, Orson W.;
- Hsia, Connie C. W.
Publication type:
Article
Molecular aspects of acute inhibition of Na+-H+ exchanger NHE3 by A2-adenosine receptor agonists.
Published in:
Journal of Physiology, 2002, v. 541, n. 2, p. 529, doi. 10.1113/jphysiol.2001.013438
By:
- Sole, Francesca;
- Cerull, Robert;
- Casavola, Valeria;
- Moe, Orson W.;
- Burckhardt, Gerhard;
- Helmle-Kolb, Corinna
Publication type:
Article
Adenosine inhibits the transfected Na+-H+ exchanger NHE3 in Xenopus laevis renal epithelial cells (A6/C1).
Published in:
Journal of Physiology, 1999, v. 515, n. 3, p. 829, doi. 10.1111/j.1469-7793.1999.829ab.x
By:
- Sole, Francesca;
- Casavola, Valeria;
- Mastroberardino, Luca;
- Verrey, François;
- Moe, Orson W.;
- Burckhardt, Gerhard;
- Murer, Heini;
- Helmle-Kolb, Corinna
Publication type:
Article
Evidence for abnormal linkage between urine oxalate and citrate excretion in human kidney stone formers.
Published in:
Physiological Reports, 2021, v. 9, n. 13, p. 1, doi. 10.14814/phy2.14943
By:
- Prochaska, Megan L.;
- Moe, Orson W.;
- Asplin, John R.;
- Coe, Fredric L.;
- Worcester, Elaine M.
Publication type:
Article
Fibroblast growth factor 23 and uremic vascular calcification: is it time to escalate from biomarker status to pathogenic agent?
Published in:
Kidney International, 2014, v. 85, n. 5, p. 1022, doi. 10.1038/ki.2013.471
By:
- Moe, Orson W;
- Kuro-o, Makoto
Publication type:
Article
Klotho has dual protective effects on cisplatin-induced acute kidney injury.
Published in:
Kidney International, 2014, v. 85, n. 4, p. 855, doi. 10.1038/ki.2013.489
By:
- Panesso, Monica C;
- Shi, Mingjun;
- Cho, Han J;
- Paek, Jean;
- Ye, Jianfeng;
- Moe, Orson W;
- Hu, Ming Chang
Publication type:
Article
The erythropoietin receptor is a downstream effector of Klotho-induced cytoprotection.
Published in:
Kidney International, 2013, v. 84, n. 3, p. 468, doi. 10.1038/ki.2013.149
By:
- Hu, Ming-Chang;
- Shi, Mingjun;
- Cho, Han J;
- Zhang, Jianning;
- Pavlenco, Alevtina;
- Liu, Shuzhen;
- Sidhu, Sachdev;
- Huang, Lily J-S;
- Moe, Orson W
Publication type:
Article
Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet.
Published in:
Kidney International, 2012, v. 82, n. 12, p. 1261, doi. 10.1038/ki.2012.322
By:
- Lau, Wei Ling;
- Leaf, Elizabeth M;
- Hu, Ming Chang;
- Takeno, Marc M;
- Kuro-o, Makoto;
- Moe, Orson W;
- Giachelli, Cecilia M
Publication type:
Article
The diurnal variation in urine acidification differs between normal individuals and uric acid stone formers.
Published in:
Kidney International, 2012, v. 81, n. 11, p. 1123, doi. 10.1038/ki.2011.480
By:
- Cameron, MaryAnn;
- Maalouf, Naim M;
- Poindexter, John;
- Adams-Huet, Beverley;
- Sakhaee, Khashayar;
- Moe, Orson W
Publication type:
Article
The reduction of Na/H exchanger-3 protein and transcript expression in acute ischemia-reperfusion injury is mediated by extractable tissue factor(s).
Published in:
Kidney International, 2011, v. 80, n. 8, p. 822, doi. 10.1038/ki.2011.229
By:
- Di Sole, Francesca;
- Hu, Ming-Chang;
- Zhang, Jianning;
- Babich, Victor;
- Bobulescu, I Alexandru;
- Shi, Mingjun;
- McLeroy, Paul;
- Rogers, Thomas E;
- Moe, Orson W
Publication type:
Article
Defining hypercalciuria in nephrolithiasis.
Published in:
Kidney International, 2011, v. 80, n. 7, p. 777, doi. 10.1038/ki.2011.227
By:
- Pak, Charles Y C;
- Sakhaee, Khashayar;
- Moe, Orson W;
- Poindexter, John;
- Adams-Huet, Beverley
Publication type:
Article
Pharmacotherapy of urolithiasis: evidence from clinical trials.
Published in:
Kidney International, 2011, v. 79, n. 4, p. 385, doi. 10.1038/ki.2010.389
By:
- Moe, Orson W.;
- Pearle, Margaret S.;
- Sakhaee, Khashayar
Publication type:
Article
Pharmacotherapy of urolithiasis: evidence from clinical trials.
Published in:
2011
By:
- Moe OW;
- Pearle MS;
- Sakhaee K;
- Moe, Orson W;
- Pearle, Margaret S;
- Sakhaee, Khashayar
Publication type:
journal article
Nephrolithiasis-associated bone disease: pathogenesis and treatment options.
Published in:
Kidney International, 2011, v. 79, n. 4, p. 393, doi. 10.1038/ki.2010.473
By:
- Sakhaee, Khashayar;
- Maalouf, Naim M.;
- Kumar, Rajiv;
- Pasch, Andreas;
- Moe, Orson W.
Publication type:
Article
Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective.
Published in:
Kidney International, 2010, v. 78, n. 12, p. 1240, doi. 10.1038/ki.2010.328
By:
- Ming-Chang Hu;
- Mingjun Shi;
- Jianning Zhang;
- Quiñones, Henry;
- Kuro-o, Makoto;
- Moe, Orson W.
Publication type:
Article
Renal phosphate wasting due to tumor-induced osteomalacia: a frequently delayed diagnosis.
Published in:
2009
By:
- Gore, M. Odette;
- Welch, Brian J.;
- Geng, Weidong;
- Kabbani, Wareef;
- Maalouf, Naim M.;
- Zerwekh, Joseph E.;
- Moe, Orson W.;
- Sakhaee, Khashayar
Publication type:
Case Study
Effect of urine pH and magnesium on calcium oxalate saturation.
Published in:
Magnesium Research, 2017, v. 30, n. 4, p. 107, doi. 10.1684/mrh.2018.0429
By:
- Ferrè, Silvia;
- Grange, Jacob S.;
- Adams-Huet, M. S. Beverley;
- Moe, Orson W.;
- Maalouf, Naim M.
Publication type:
Article
Acute Kidney Injury After Burn: A Cohort Study From the Parkland Burn Intensive Care Unit.
Published in:
2019
By:
- Clark, Audra T;
- Li, Xilong;
- Kulangara, Rohan;
- Adams-Huet, Beverley;
- Huen, Sarah C;
- Madni, Tarik D;
- Imran, Jonathan B;
- Phelan, Herb A;
- Arnoldo, Brett D;
- Moe, Orson W;
- Wolf, Steven E;
- Neyra, Javier A
Publication type:
journal article
Hypercalciuria associated with high dietary protein intake is not due to acid load.
Published in:
2011
By:
- Maalouf, Naim M;
- Moe, Orson W;
- Adams-Huet, Beverley;
- Sakhaee, Khashayar
Publication type:
journal article
Triglycerides in the Human Kidney Cortex: Relationship with Body Size.
Published in:
PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0101285
By:
- Bobulescu, Ion Alexandru;
- Lotan, Yair;
- Zhang, Jianning;
- Rosenthal, Tara R.;
- Rogers, John T.;
- Adams-Huet, Beverley;
- Sakhaee, Khashayar;
- Moe, Orson W.
Publication type:
Article
Uric acid transport, transporters, and their pharmacological targeting.
Published in:
Acta Physiologica, 2023, v. 238, n. 2, p. 1, doi. 10.1111/apha.13980
By:
- Adomako, Emmanuel A.;
- Moe, Orson W.
Publication type:
Article
High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis.
Published in:
Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01273
By:
- Maique, Jenny;
- Flores, Brianna;
- Shi, Mingjun;
- Shepard, Sierra;
- Zhou, Zhiyong;
- Yan, Shirely;
- Moe, Orson W.;
- Hu, Ming Chang
Publication type:
Article
Novel Human Polymorphisms Define a Key Role for the SLC26A6-STAS Domain in Protection From Ca2+-Oxalate Lithogenesis.
Published in:
Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00405
By:
- Shimshilashvili, Liana;
- Aharon, Sara;
- Moe, Orson W.;
- Ohana, Ehud
Publication type:
Article
Cellular model of proximal tubule NaCl and NaHCO[sub3] absorption.
Published in:
Kidney International, 1990, v. 38, n. 4, p. 605, doi. 10.1038/ki.1990.249
By:
- Moe, Orson W.;
- Preisig, Patricia A.;
- Alpern, Robert J.
Publication type:
Article
Hypertrophy of human embryonic stem cell–derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals.
Published in:
Pflügers Archiv: European Journal of Physiology, 2019, v. 471, n. 8, p. 1143, doi. 10.1007/s00424-019-02293-0
By:
- Deisl, Christine;
- Fine, Michael;
- Moe, Orson W.;
- Hilgemann, Donald W.
Publication type:
Article
Role of αKlotho and FGF23 in regulation of type II Na-dependent phosphate co-transporters.
Published in:
Pflügers Archiv: European Journal of Physiology, 2019, v. 471, n. 1, p. 99, doi. 10.1007/s00424-018-2238-5
By:
- Hu, Ming Chang;
- Shi, Mingjun;
- Moe, Orson W.
Publication type:
Article
Klotho: a novel regulator of calcium and phosphorus homeostasis.
Published in:
Pflügers Archiv: European Journal of Physiology, 2011, v. 462, n. 2, p. 185, doi. 10.1007/s00424-011-0950-5
By:
- Huang, Chou-Long;
- Moe, Orson
Publication type:
Article
Luminal Na+/H+ exchange in the proximal tubule.
Published in:
Pflügers Archiv: European Journal of Physiology, 2009, v. 458, n. 1, p. 5, doi. 10.1007/s00424-008-0595-1
By:
- Bobulescu, I. Alexandru;
- Moe, Orson W.
Publication type:
Article
An apical membrane Na+/H+ exchanger isoform, NHE-3, is present in the rat epididymal epithelium.
Published in:
Pflügers Archiv: European Journal of Physiology, 2001, v. 442, n. 2, p. 230, doi. 10.1007/s004240100530
By:
- Kaunisto, Kari;
- Moe, Orson W.;
- Pelto-Huikko, Markku;
- Traebert, Martin;
- Rajaniemi, Hannu
Publication type:
Article
'Reviving' the call for standardization of the composite outcome of major adverse kidney events in critical care nephrology research.
Published in:
Intensive Care Medicine, 2024, v. 50, n. 5, p. 784, doi. 10.1007/s00134-024-07429-0
By:
- Flannery, Alexander H.;
- Woodward, Blake M.;
- Barreto, Erin F.;
- Moe, Orson W.;
- Neyra, Javier A.
Publication type:
Article
Central Calcineurin Plays a Role in Skeletal Muscle Reflex Overactivity Induced by High Dietary Phosphate Intake in Rats.
Published in:
FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04453
By:
- Kim, Han‐Kyul;
- Mizuno, Masaki;
- Mitchell, Jere;
- Pastor, Johanne;
- Moe, Orson;
- Smith, Scott;
- Rothermel, Beverly;
- Vongpatanasin, Wanpen
Publication type:
Article
The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance.
Published in:
FASEB Journal, 2020, v. 34, n. 2, p. 3129, doi. 10.1096/fj.201902127R
By:
- Shi, Mingjun;
- Maique, Jenny;
- Shaffer, Joy;
- Davidson, Taylor;
- Sebti, Salwa;
- Fernández, Álvaro F.;
- Zou, Zhongju;
- Yan, Shirley;
- Levine, Beth;
- Moe, Orson W.;
- Hu, Ming Chang
Publication type:
Article
Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule.
Published in:
FASEB Journal, 2010, v. 24, n. 9, p. 3438, doi. 10.1096/fj.10-154765
By:
- Hu, Ming Chang;
- Shi, Mingjun;
- Zhang, Jianning;
- Pastor, Johanne;
- Nakatani, Teruyo;
- Lanske, Beate;
- Razzaque, M. Shawkat;
- Rosenblatt, Kevin P.;
- Baum, Michel G.;
- Kuro-o, Makoto;
- Moe, Orson W.
Publication type:
Article
A generic crystallopathic model for chronic kidney disease progression.
Published in:
2021
By:
- Moe, Orson W.
Publication type:
journal article
The kidney stone and increased water intake trial in steel workers: results from a pilot study.
Published in:
Urolithiasis, 2017, v. 45, n. 2, p. 177, doi. 10.1007/s00240-016-0892-7
By:
- Lotan, Yair;
- Antonelli, Jodi;
- Jiménez, Inmaculada;
- Gharbi, Hakam;
- Herring, Ron;
- Beaver, Allison;
- Dennis, Aphrihl;
- Merveldt, Dendra;
- Carter, Suzie;
- Cohen, Adam;
- Poindexter, John;
- Moe, Orson;
- Pearle, Margaret
Publication type:
Article
Performance of soluble Klotho assays in clinical samples of kidney disease.
Published in:
Clinical Kidney Journal, 2020, v. 13, n. 2, p. 235, doi. 10.1093/ckj/sfz085
By:
- Neyra, Javier A;
- Moe, Orson W;
- Pastor, Johanne;
- Gianella, Fabiola;
- Sidhu, Sachdev S;
- Sarnak, Mark J;
- Ix, Joachim H;
- Drew, David A
Publication type:
Article
Serum IL-17 levels are higher in critically ill patients with AKI and associated with worse outcomes.
Published in:
2022
By:
- Collett, Jason A.;
- Ortiz-Soriano, Victor;
- Li, Xilong;
- Flannery, Alexander H.;
- Toto, Robert D.;
- Moe, Orson W.;
- Basile, David P.;
- Neyra, Javier A.
Publication type:
journal article
Post-pneumonectomy (PNX) lung expansion enhances expression of erythropoietin receptor (EPO-R) through an Akt-associated pathway.
Published in:
FASEB Journal, 2007, v. 21, n. 6, p. A1202, doi. 10.1096/fasebj.21.6.a1202-b
By:
- Quiyang Zhang;
- Moe, Orson W.;
- Hsia, Connie C. W.
Publication type:
Article
Fibroblast growth factor 23 and acute kidney injury.
Published in:
Pediatric Nephrology, 2015, v. 30, n. 11, p. 1909, doi. 10.1007/s00467-014-3006-1
By:
- Neyra, Javier;
- Moe, Orson;
- Hu, Ming
Publication type:
Article
Nephrolithiasis in children.
Published in:
Pediatric Nephrology, 2005, v. 20, n. 11, p. 1587, doi. 10.1007/s00467-005-1883-z
By:
- Cameron, Mary Ann;
- Sakhaee, Khashayar;
- Moe, Orson W.
Publication type:
Article
The pathophysiology of the chronic kidney disease-mineral bone disorder: synopsis of a symposium at the Sun Valley Musculoskeletal Biology Workshop.
Published in:
IBMS BoneKEy, 2013, v. 10, n. 11, p. 444, doi. 10.1038/bonekey.2013.178
By:
- Hruska, Keith A;
- Leonard, Mary;
- Pereira, Renata;
- White, Kenneth E;
- Moe, Orson W
Publication type:
Article
Inhibition of osteoclast formation and function by bicarbonate: Role of soluble adenylyl cyclase.
Published in:
Journal of Cellular Physiology, 2009, v. 220, n. 2, p. 332, doi. 10.1002/jcp.21767
By:
- WEIDONG GENG;
- HILL, KATHY;
- ZERWEKH, JOSEPH E.;
- KOHLER, THOMAS;
- MÜLLER, RALPH;
- MOE, ORSON W.
Publication type:
Article

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