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Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.
Published in:
Biochemical Journal, 2015, v. 468, n. 2, p. 245, doi. 10.1042/BJ20150270
By:
- Mobbs, Jesse I.;
- Koay, Ann;
- Di Paolo, Alex;
- Bieri, Michael;
- Petrie, Emma J.;
- Gorman, Michael A.;
- Doughty, Larissa;
- Parker, Michael W.;
- Stapleton, David I.;
- Griffin, Michael D. W.;
- Gooley, Paul R.
Publication type:
Article
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M<sub>4</sub> mAChR.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41199-5
By:
- Burger, Wessel A. C.;
- Pham, Vi;
- Vuckovic, Ziva;
- Powers, Alexander S.;
- Mobbs, Jesse I.;
- Laloudakis, Yianni;
- Glukhova, Alisa;
- Wootten, Denise;
- Tobin, Andrew B.;
- Sexton, Patrick M.;
- Paul, Steven M.;
- Felder, Christian C.;
- Danev, Radostin;
- Dror, Ron O.;
- Christopoulos, Arthur;
- Valant, Celine;
- Thal, David M.
Publication type:
Article
Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling.
Published in:
PLoS Biology, 2024, v. 22, n. 7, p. 1, doi. 10.1371/journal.pbio.3002673
By:
- Harikumar, Kaleeckal G.;
- Zhao, Peishen;
- Cary, Brian P.;
- Xu, Xiaomeng;
- Desai, Aditya J.;
- Dong, Maoqing;
- Mobbs, Jesse I.;
- Toufaily, Chirine;
- Furness, Sebastian G. B.;
- Christopoulos, Arthur;
- Belousoff, Matthew J.;
- Wootten, Denise;
- Sexton, Patrick M.;
- Miller, Laurence J.
Publication type:
Article
Unravelling the Carbohydrate‐Binding Preferences of the Carbohydrate‐Binding Modules of AMP‐Activated Protein Kinase.
Published in:
ChemBioChem, 2018, v. 19, n. 3, p. 229, doi. 10.1002/cbic.201700589
By:
- Mobbs, Jesse I.;
- Di Paolo, Alex;
- Metcalfe, Riley D.;
- Selig, Emily;
- Stapleton, David I.;
- Griffin, Michael D. W.;
- Gooley, Paul R.
Publication type:
Article
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity.
Published in:
PLoS Biology, 2021, v. 19, n. 6, p. 1, doi. 10.1371/journal.pbio.3001295
By:
- Mobbs, Jesse I.;
- Belousoff, Matthew J.;
- Harikumar, Kaleeckal G.;
- Piper, Sarah J.;
- Xu, Xiaomeng;
- Furness, Sebastian G. B.;
- Venugopal, Hari;
- Christopoulos, Arthur;
- Danev, Radostin;
- Wootten, Denise;
- Thal, David M.;
- Miller, Laurence J.;
- Sexton, Patrick M.
Publication type:
Article
Structural and regulatory diversity shape HLA-C protein expression levels.
Published in:
Nature Communications, 2017, v. 8, n. 6, p. 15924, doi. 10.1038/ncomms15924
By:
- Kaur, Gurman;
- Gras, Stephanie;
- Mobbs, Jesse I.;
- Vivian, Julian P.;
- Cortes, Adrian;
- Barber, Thomas;
- Kuttikkatte, Subita Balaram;
- Jensen, Lise Torp;
- Attfield, Kathrine E.;
- Dendrou, Calliope A.;
- Carrington, Mary;
- McVean, Gil;
- Purcell, Anthony W.;
- Rossjohn, Jamie;
- Fugger, Lars
Publication type:
Article
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.83477
By:
- Vuckovic, Ziva;
- Jinan Wang;
- Vi Pham;
- Mobbs, Jesse I.;
- Belousoff, Matthew J.;
- Bhattarai, Apurba;
- Burger, Wessel A. C.;
- Thompson, Geoff;
- Yeasmin, Mahmuda;
- Nawaratne, Vindhya;
- Leach, Katie;
- van der Westhuizen, Emma T.;
- Khajehali, Elham;
- Yi-Lynn Liang;
- Glukhova, Alisa;
- Wootten, Denise;
- Lindsley, Craig W.;
- Tobin, Andrew;
- Sexton, Patrick;
- Danev, Radostin
Publication type:
Article
Structural insights into the human P2X1 receptor and ligand interactions.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52776-7
By:
- Bennetts, Felix M.;
- Venugopal, Hariprasad;
- Glukhova, Alisa;
- Mobbs, Jesse I.;
- Ventura, Sabatino;
- Thal, David M.
Publication type:
Article

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