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Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers.
Published in:
Nature Communications, 2015, v. 6, n. 9, p. 8305, doi. 10.1038/ncomms9305
By:
- Misale, Sandra;
- Bozic, Ivana;
- Tong, Jingshan;
- Peraza-Penton, Ashley;
- Lallo, Alice;
- Baldi, Federica;
- Lin, Kevin H.;
- Truini, Mauro;
- Trusolino, Livio;
- Bertotti, Andrea;
- Di Nicolantonio, Federica;
- Nowak, Martin A.;
- Zhang, Lin;
- Wood, Kris C.;
- Bardelli, Alberto
Publication type:
Article
MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations.
Published in:
Science Translational Medicine, 2016, v. 8, n. 324, p. 1, doi. 10.1126/scitranslmed.aad5640
By:
- Arena, Sabrina;
- Siravegna, Giulia;
- Mussolin, Benedetta;
- Kearns, Jeffrey D.;
- Wolf, Beni B.;
- Misale, Sandra;
- Lazzari, Luca;
- Bertotti, Andrea;
- Trusolino, Livio;
- Adjei, Alex A.;
- Montagut, Clara;
- Di Nicolantonio, Federica;
- Nering, Rachel;
- Bardelli, Alberto
Publication type:
Article
KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
Published in:
International Journal of Cancer, 2013, v. 133, n. 5, p. 1259, doi. 10.1002/ijc.28106
By:
- Valtorta, Emanuele;
- Misale, Sandra;
- Sartore‐Bianchi, Andrea;
- Nagtegaal, Iris D.;
- Paraf, François;
- Lauricella, Calogero;
- Dimartino, Valentina;
- Hobor, Sebastijan;
- Jacobs, Bart;
- Ercolani, Cristiana;
- Lamba, Simona;
- Scala, Elisa;
- Veronese, Silvio;
- Laurent‐Puig, Pierre;
- Siena, Salvatore;
- Tejpar, Sabine;
- Mottolese, Marcella;
- Punt, Cornelis J.A.;
- Gambacorta, Marcello;
- Bardelli, Alberto
Publication type:
Article
Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer.
Published in:
Science Translational Medicine, 2014, v. 6, n. 224, p. 1, doi. 10.1126/scitranslmed.3007947
By:
- Misale, Sandra;
- Arena, Sabrina;
- Lamba, Simona;
- Siravegna, Giulia;
- Lallo, Alice;
- Hobor, Sebastijan;
- Russo, Mariangela;
- Buscarino, Michela;
- Lazzari, Luca;
- Sartore-Bianchi, Andrea;
- Bencardino, Katia;
- Amatu, Alessio;
- Lauricella, Calogero;
- Valtorta, Emanuele;
- Siena, Salvatore;
- Di Nicolantonio, Federica;
- Bardelli, Alberto
Publication type:
Article
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
Published in:
Nature, 2012, v. 486, n. 7404, p. 532, doi. 10.1038/nature11156
By:
- Misale, Sandra;
- Yaeger, Rona;
- Hobor, Sebastijan;
- Scala, Elisa;
- Janakiraman, Manickam;
- Liska, David;
- Valtorta, Emanuele;
- Schiavo, Roberta;
- Buscarino, Michela;
- Siravegna, Giulia;
- Bencardino, Katia;
- Cercek, Andrea;
- Chen, Chin-Tung;
- Veronese, Silvio;
- Zanon, Carlo;
- Sartore-Bianchi, Andrea;
- Gambacorta, Marcello;
- Gallicchio, Margherita;
- Vakiani, Efsevia;
- Boscaro, Valentina
Publication type:
Article
Combined RAF and MEK Inhibition to Treat Activated Non-V600 BRAF-Altered Advanced Cancers.
Published in:
Oncologist, 2024, v. 29, n. 1, p. 15, doi. 10.1093/oncolo/oyad247
By:
- Rustgi, Naryan;
- Maria, Ann;
- Toumbacaris, Nicolas;
- Zhao, HuiYong;
- Kargus, Katherine;
- Bryant, Morgan;
- Waksmundzki, Alexandra;
- Aricescu, Ilinca;
- Lefkowitz, Robert A;
- Li, Bob T;
- Chou, Joanne;
- Capanu, Marinela;
- Stanchina, Elisa de;
- Misale, Sandra;
- Shia, Jinru;
- Yaeger, Rona
Publication type:
Article
Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer.
Published in:
2016
By:
- Sartore-Bianchi, Andrea;
- Ardini, Elena;
- Bosotti, Roberta;
- Amatu, Alessio;
- Valtorta, Emanuele;
- Somaschini, Alessio;
- Raddrizzani, Laura;
- Palmeri, Laura;
- Banfi, Patrizia;
- Bonazzina, Erica;
- Misale, Sandra;
- Marrapese, Giovanna;
- Leone, Antonella;
- Alzani, Rachele;
- Luo, David;
- Hornby, Zachary;
- Lim, Jonathan;
- Veronese, Silvio;
- Vanzulli, Angelo;
- Bardelli, Alberto
Publication type:
journal article

Found: 7

Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers.

MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations.

KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.

Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer.

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.

Combined RAF and MEK Inhibition to Treat Activated Non-V600 BRAF-Altered Advanced Cancers.

Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer.