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Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
Published in:
PLoS Genetics, 2018, v. 14, n. 11, p. 1, doi. 10.1371/journal.pgen.1007755
By:
- Nanda, Vivek;
- Wang, Ting;
- Pjanic, Milos;
- Liu, Boxiang;
- Nguyen, Trieu;
- Matic, Ljubica Perisic;
- Hedin, Ulf;
- Koplev, Simon;
- Ma, Lijiang;
- Franzén, Oscar;
- Ruusalepp, Arno;
- Schadt, Eric E.;
- Björkegren, Johan L. M.;
- Montgomery, Stephen B.;
- Snyder, Michael P.;
- Quertermous, Thomas;
- Leeper, Nicholas J.;
- Miller, Clint L.
Publication type:
Article
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.
Published in:
PLoS Genetics, 2018, v. 14, n. 10, p. 1, doi. 10.1371/journal.pgen.1007681
By:
- Iyer, Dharini;
- Zhao, Quanyi;
- Wirka, Robert;
- Naravane, Ameay;
- Nguyen, Trieu;
- Liu, Boxiang;
- Nagao, Manabu;
- Cheng, Paul;
- Miller, Clint L.;
- Kim, Juyong Brian;
- Pjanic, Milos;
- Quertermous, Thomas
Publication type:
Article
An automatic entropy method to efficiently mask histology whole-slide images.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-29638-1
By:
- Song, Yipei;
- Cisternino, Francesco;
- Mekke, Joost M.;
- de Borst, Gert J.;
- de Kleijn, Dominique P. V.;
- Pasterkamp, Gerard;
- Vink, Aryan;
- Glastonbury, Craig A.;
- van der Laan, Sander W.;
- Miller, Clint L.
Publication type:
Article
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells.
Published in:
PLoS Genetics, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.pgen.1006750
By:
- Kim, Juyong Brian;
- Pjanic, Milos;
- Nguyen, Trieu;
- Miller, Clint L.;
- Iyer, Dharini;
- Liu, Boxiang;
- Wang, Ting;
- Sazonova, Olga;
- Carcamo-Orive, Ivan;
- Matic, Ljubica Perisic;
- Maegdefessel, Lars;
- Hedin, Ulf;
- Quertermous, Thomas
Publication type:
Article
The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis.
Published in:
European Heart Journal, 2019, v. 40, n. 29, p. 2398, doi. 10.1093/eurheartj/ehz303
By:
- Xu, Suowen;
- Xu, Yanni;
- Liu, Peng;
- Zhang, Shuya;
- Liu, Huan;
- Slavin, Spencer;
- Kumar, Sandeep;
- Koroleva, Marina;
- Luo, Jinque;
- Wu, Xiaoqian;
- Rahman, Arshad;
- Pelisek, Jaroslav;
- Jo, Hanjoong;
- Si, Shuyi;
- Miller, Clint L;
- Jin, Zheng Gen
Publication type:
Article
Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells.
Published in:
Cardiovascular Research, 2022, v. 118, n. 13, p. 2792, doi. 10.1093/cvr/cvab347
By:
- Wang, Ying;
- Gao, Hua;
- Wang, Fudi;
- Ye, Zhongde;
- Mokry, Michal;
- Turner, Adam W;
- Ye, Jianqin;
- Koplev, Simon;
- Luo, Lingfeng;
- Alsaigh, Tom;
- Adkar, Shaunak S;
- Elishaev, Maria;
- Gao, Xiangyu;
- Maegdefessel, Lars;
- Björkegren, Johan L M;
- Pasterkamp, Gerard;
- Miller, Clint L;
- Ross, Elsie G;
- Leeper, Nicholas J
Publication type:
Article
Ca.
Published in:
FEBS Journal, 2010, v. 277, n. 24, p. 5026, doi. 10.1111/j.1742-4658.2010.07908.x
By:
- Jeon, Kye-Im;
- Jono, Hirofumi;
- Miller, Clint L.;
- Cai, Yujun;
- Lim, Soyeon;
- Liu, Xuan;
- Gao, Pingjin;
- Abe, Jun-Ichi;
- Li, Jian-Dong;
- Yan, Chen
Publication type:
Article
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci.
Published in:
Nature Communications, 2016, v. 7, n. 7, p. 12092, doi. 10.1038/ncomms12092
By:
- Miller, Clint L.;
- Pjanic, Milos;
- Wang, Ting;
- Nguyen, Trieu;
- Cohain, Ariella;
- Lee, Jonathan D.;
- Perisic, Ljubica;
- Hedin, Ulf;
- Kundu, Ramendra K.;
- Majmudar, Deshna;
- Kim, Juyong B.;
- Wang, Oliver;
- Betsholtz, Christer;
- Ruusalepp, Arno;
- Franzén, Oscar;
- Assimes, Themistocles L.;
- Montgomery, Stephen B.;
- Schadt, Eric E.;
- Björkegren, Johan L.M.;
- Quertermous, Thomas
Publication type:
Article
Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data.
Published in:
PLoS Genetics, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pgen.1005496
By:
- Dewey, Frederick E.;
- Grove, Megan E.;
- Priest, James R.;
- Waggott, Daryl;
- Batra, Prag;
- Miller, Clint L.;
- Wheeler, Matthew;
- Zia, Amin;
- Pan, Cuiping;
- Karzcewski, Konrad J.;
- Miyake, Christina;
- Whirl-Carrillo, Michelle;
- Klein, Teri E.;
- Datta, Somalee;
- Altman, Russ B.;
- Snyder, Michael;
- Quertermous, Thomas;
- Ashley, Euan A.
Publication type:
Article
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap.
Published in:
PLoS Genetics, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pgen.1005155
By:
- Nurnberg, Sylvia T.;
- Cheng, Karen;
- Raiesdana, Azad;
- Kundu, Ramendra;
- Miller, Clint L.;
- Kim, Juyong B.;
- Arora, Komal;
- Carcamo-Oribe, Ivan;
- Xiong, Yiqin;
- Tellakula, Nikhil;
- Nanda, Vivek;
- Murthy, Nikitha;
- Boisvert, William A.;
- Hedin, Ulf;
- Perisic, Ljubica;
- Aldi, Silvia;
- Maegdefessel, Lars;
- Pjanic, Milos;
- Owens, Gary K.;
- Tallquist, Michelle D.
Publication type:
Article
Coronary Heart Disease-Associated Variation in <i>TCF21</i> Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation.
Published in:
PLoS Genetics, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pgen.1004263
By:
- Miller, Clint L.;
- Haas, Ulrike;
- Diaz, Roxanne;
- Leeper, Nicholas J.;
- Kundu, Ramendra K.;
- Patlolla, Bhagat;
- Assimes, Themistocles L.;
- Kaiser, Frank J.;
- Perisic, Ljubica;
- Hedin, Ulf;
- Maegdefessel, Lars;
- Schunkert, Heribert;
- Erdmann, Jeanette;
- Quertermous, Thomas;
- Sczakiel, Georg
Publication type:
Article
Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of <i>TCF21</i> Expression at the 6q23.2 Coronary Heart Disease Locus.
Published in:
PLoS Genetics, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.pgen.1003652
By:
- Miller, Clint L.;
- Anderson, D. Ryan;
- Kundu, Ramendra K.;
- Raiesdana, Azad;
- Nürnberg, Sylvia T.;
- Diaz, Roxanne;
- Cheng, Karen;
- Leeper, Nicholas J.;
- Chen, Chung-Hsing;
- Chang, I-Shou;
- Schadt, Eric E.;
- Hsiung, Chao Agnes;
- Assimes, Themistocles L.;
- Quertermous, Thomas
Publication type:
Article
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.
Published in:
Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1235337
By:
- de las Fuentes, Lisa;
- Schwander, Karen L.;
- Brown, Michael R.;
- Bentley, Amy R.;
- Winkler, Thomas W.;
- Yun Ju Sung;
- Munroe, Patricia B.;
- Miller, Clint L.;
- Hugo Aschard;
- Aslibekyan, Stella;
- Bartz, Traci M.;
- Bielak, Lawrence F.;
- Jin Fang Chai;
- Ching-Yu Cheng;
- Dorajoo, Rajkumar;
- Feitosa, Mary F.;
- Xiuqing Guo;
- Hartwig, Fernando P.;
- Horimoto, Andrea;
- Kolčić, Ivana
Publication type:
Article
Association between BMD and coronary artery calcification: an observational and Mendelian randomization study.
Published in:
Journal of Bone & Mineral Research, 2024, v. 39, n. 4, p. 443, doi. 10.1093/jbmr/zjae022
By:
- Lu, Haojie;
- Lary, Christine W;
- Hodonsky, Chani J;
- Peyser, Patricia A;
- Bos, Daniel;
- Laan, Sander W van der;
- Miller, Clint L;
- Rivadeneira, Fernando;
- Kiel, Douglas P;
- Kavousi, Maryam;
- Medina-Gomez, Carolina
Publication type:
Article
The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1.
Published in:
PLoS Genetics, 2022, v. 18, n. 6, p. 1, doi. 10.1371/journal.pgen.1010261
By:
- Ma, Lijiang;
- Bryce, Nicole S.;
- Turner, Adam W.;
- Di Narzo, Antonio F.;
- Rahman, Karishma;
- Xu, Yang;
- Ermel, Raili;
- Sukhavasi, Katyayani;
- d'Escamard, Valentina;
- Chandel, Nirupama;
- V'Gangula, Bhargavi;
- Wolhuter, Kathryn;
- Kadian-Dodov, Daniella;
- Franzen, Oscar;
- Ruusalepp, Arno;
- Hao, Ke;
- Miller, Clint L.;
- Björkegren, Johan L. M.;
- Kovacic, Jason C.
Publication type:
Article
Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart.
Published in:
Basic Research in Cardiology, 2011, v. 106, n. 6, p. 1023, doi. 10.1007/s00395-011-0228-2
By:
- Miller, Clint L.;
- Yujun Cai;
- Masayoshi Oikawa;
- Thomas, Tamlyn;
- Dostmann, Wolfgang R.;
- Zaccolo, Manuela;
- Fujiwara, Keigi;
- Chen Yan
Publication type:
Article
The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological symptoms.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43369-3
By:
- Mekke, Joost M.;
- Sakkers, Tim R.;
- Verwer, Maarten C.;
- van den Dungen, Noortje A. M.;
- Song, Yipei;
- Miller, Clint L.;
- Finn, Aloke V.;
- Pasterkamp, Gerard;
- Mokry, Michal;
- den Ruijter, Hester M.;
- Vink, Aryan;
- de Kleijn, Dominique P. V.;
- de Borst, Gert J.;
- Haitjema, Saskia;
- van der Laan, Sander W.
Publication type:
Article
The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological symptoms.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43369-3
By:
- Mekke, Joost M.;
- Sakkers, Tim R.;
- Verwer, Maarten C.;
- van den Dungen, Noortje A. M.;
- Song, Yipei;
- Miller, Clint L.;
- Finn, Aloke V.;
- Pasterkamp, Gerard;
- Mokry, Michal;
- den Ruijter, Hester M.;
- Vink, Aryan;
- de Kleijn, Dominique P. V.;
- de Borst, Gert J.;
- Haitjema, Saskia;
- van der Laan, Sander W.
Publication type:
Article
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression.
Published in:
Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0635-9
By:
- Zhao, Quanyi;
- Wirka, Robert;
- Nguyen, Trieu;
- Nagao, Manabu;
- Cheng, Paul;
- Miller, Clint L.;
- Kim, Juyong Brian;
- Pjanic, Milos;
- Quertermous, Thomas
Publication type:
Article

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