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Pharmacokinetics of Irinotecan, Oxaliplatin and 5-Fluorouracil During Hepatic Artery Chronomodulated Infusion: A Translational European OPTILIV Study.
- Published in:
- 2017
- By:
- Publication type:
- journal article
A clinical pharmacokinetic analysis of tegafur-uracil (UFT) plus leucovorin given in a new twice-daily oral administration schedule.
- Published in:
- 2007
- By:
- Publication type:
- journal article
PRIMUM NON NOCERE: now and again an echo of DPD with capecitabine.
- Published in:
- 2017
- By:
- Publication type:
- letter
Correction to: Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors.
- Published in:
- 2021
- By:
- Publication type:
- Correction Notice
Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors.
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 1, p. 160, doi. 10.1007/s10637-019-00845-w
- By:
- Publication type:
- Article
Resistance to immunotherapy: clouds in a bright sky.
- Published in:
- Investigational New Drugs, 2017, v. 35, n. 5, p. 649, doi. 10.1007/s10637-017-0456-x
- By:
- Publication type:
- Article
Treatment effect of buparlisib, cetuximab and irradiation in wild-type or PI3KCA-mutated head and neck cancer cell lines.
- Published in:
- Investigational New Drugs, 2015, v. 33, n. 2, p. 310, doi. 10.1007/s10637-015-0210-1
- By:
- Publication type:
- Article
Combination of bevacizumab and irradiation on uveal melanoma: an in vitro and in vivo preclinical study.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 1, p. 59, doi. 10.1007/s10637-012-9834-6
- By:
- Publication type:
- Article
Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity.
- Published in:
- Human Genetics, 2010, v. 128, n. 5, p. 529, doi. 10.1007/s00439-010-0879-3
- By:
- Publication type:
- Article
Determination of microsatellite instability, p53 and K- RAS mutations in hepatic metastases from patients with colorectal cancer: Relationship with response to 5-fluorouracil and survival.
- Published in:
- International Journal of Cancer, 2001, v. 95, n. 3, p. 162, doi. 10.1002/1097-0215(20010520)95:3<162::AID-IJC1028>3.0.CO;2-J
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- Publication type:
- Article
Life-threatening 5-fluorouracil-like cardiac toxicity after treatment with 5-fluorocytosine.
- Published in:
- Clinical Pharmacology & Therapeutics, 2000, v. 67, n. 3, p. 323, doi. 10.1067/mcp.2000.104643
- By:
- Publication type:
- Article
Age-related difference in tamoxifen disposition.
- Published in:
- Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 4, p. 401, doi. 10.1016/S0009-9236(96)90108-3
- By:
- Publication type:
- Article
Spontaneous or imposed circadian changes in plasma concentrations of 5-fluorouracil coadministered with folinic acid and oxaliplatin: Relationship with mucosal toxicity in patients with cancer.
- Published in:
- Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 2, p. 190, doi. 10.1038/clpt.1994.123
- By:
- Publication type:
- Article
Oxaliplatin In Operable Colorectal Cancer: A Viewpoint by Gérard Milano.
- Published in:
- Drugs, 2005, v. 65, n. 1, p. 97, doi. 10.2165/00003495-200565010-00006
- By:
- Publication type:
- Article
Tumoral platinum concentrations in patients treated with repeated low-dose cisplatin as a radiosensitizer.
- Published in:
- International Journal of Cancer, 1996, v. 68, n. 4, p. 452, doi. 10.1002/(SICI)1097-0215(19961115)68:4<452::AID-IJC9>3.0.CO;2-#
- By:
- Publication type:
- Article
Comment on: "Exploring the best treatment options for BRAF-mutant metastatic colon cancer".
- Published in:
- 2020
- By:
- Publication type:
- letter
Combination of mTOR and EGFR targeting in an orthotopic xenograft model of head and neck cancer.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Long-Term Pharmacokinetic Follow-Up of Abiraterone Acetate in Patients with Metastatic Castration-Resistant Prostate Cancer.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 6058, doi. 10.3390/ijms25116058
- By:
- Publication type:
- Article
The raltitrexed-vinorelbine combination: a phase I pharmacokinetic and pharmacodynamic trial in advanced breast cancer.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 6, p. 459, doi. 10.1007/s00280-002-0519-2
- By:
- Publication type:
- Article
Optimizing drug development in oncology by clinical trial simulation: Why and how?
- Published in:
- Briefings in Bioinformatics, 2018, v. 19, n. 6, p. 1203, doi. 10.1093/bib/bbx055
- By:
- Publication type:
- Article
Sedimentation rate and serum thymidine kinase activity: Prognostic factors in squamous cell head and neck cancer.
- Published in:
- Head & Neck, 1993, v. 15, n. 5, p. 425, doi. 10.1002/hed.2880150510
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- Publication type:
- Article
Characterization, quantification, and potential clinical value of the epidermal growth factor receptor in head and neck squamous cell carcinomas.
- Published in:
- Head & Neck, 1991, v. 13, n. 2, p. 132, doi. 10.1002/hed.2880130209
- By:
- Publication type:
- Article
High-resolution analysis of DNA copy number alterations in rectal cancer.
- Published in:
- Strahlentherapie und Onkologie, 2014, v. 190, n. 11, p. 1028, doi. 10.1007/s00066-014-0659-4
- By:
- Publication type:
- Article
High-resolution analysis of DNA copy number alterations in rectal cancer: correlation with metastasis, survival, and mRNA expression.
- Published in:
- 2014
- By:
- Publication type:
- journal article
PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer.
- Published in:
- Cancer Medicine, 2015, v. 4, n. 3, p. 371, doi. 10.1002/cam4.370
- By:
- Publication type:
- Article
Hyperprogression under Immune Checkpoint Inhibitor: a potential role for germinal immunogenetics.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-60437-0
- By:
- Publication type:
- Article
Performance and Cost Efficiency of <i>KRAS</i> Mutation Testing for Metastatic Colorectal Cancer in Routine Diagnosis: The MOKAECM Study, a Nationwide Experience.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068945
- By:
- Publication type:
- Article
Dual Role of Sp3 Transcription Factor as an Inducer of Apoptosis and a Marker of Tumour Aggressiveness.
- Published in:
- PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004478
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- Publication type:
- Article
Beating the odds: efficacy and toxicity of dihydropyrimidine dehydrogenase-driven adaptive dosing of 5-FU in patients with digestive cancer.
- Published in:
- British Journal of Clinical Pharmacology, 2016, v. 81, n. 1, p. 124, doi. 10.1111/bcp.12790
- By:
- Publication type:
- Article
Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab-irinotecan.
- Published in:
- British Journal of Clinical Pharmacology, 2012, v. 73, n. 5, p. 776, doi. 10.1111/j.1365-2125.2011.04141.x
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- Publication type:
- Article
Prospective analysis of the impact of VEGF-A gene polymorphisms on the pharmacodynamics of bevacizumab-based therapy in metastatic breast cancer patients.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 71, n. 6, p. 921, doi. 10.1111/j.1365-2125.2010.03896.x
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- Publication type:
- Article
Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and FOLFOX response in colorectal cancer patients.
- Published in:
- British Journal of Clinical Pharmacology, 2010, v. 69, n. 1, p. 58, doi. 10.1111/j.1365-2125.2009.03556.x
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- Publication type:
- Article
Candidate mechanisms for capecitabine-related hand–foot syndrome.
- Published in:
- British Journal of Clinical Pharmacology, 2008, v. 66, n. 1, p. 88, doi. 10.1111/j.1365-2125.2008.03159.x
- By:
- Publication type:
- Article
Dihydropyrimidine dehydrogenase activity and the IVS14+1G>A mutation in patients developing 5FU-related toxicity.
- Published in:
- British Journal of Clinical Pharmacology, 2007, v. 64, n. 2, p. 237, doi. 10.1111/j.1365-2125.2007.02869.x
- By:
- Publication type:
- Article
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer.
- Published in:
- Head & Neck, 2017, v. 39, n. 1, p. 151, doi. 10.1002/hed.24560
- By:
- Publication type:
- Article
Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency.
- Published in:
- 1993
- By:
- Publication type:
- case study
l-Folinic Acid Versus d,l-Folinic Acid in Rescue of High-Dose Methotrexate Therapy in Children.
- Published in:
- JNCI: Journal of the National Cancer Institute, 1992, v. 84, n. 15, p. 1190
- By:
- Publication type:
- Article
Phase I Trial of 5-Day Continuous Venous Infusion of Oxaliplatin at Circadian Rhythm-Modulated Rate Compared With Constant Rate.
- Published in:
- JNCI: Journal of the National Cancer Institute, 1990, v. 82, n. 12, p. 1046
- By:
- Publication type:
- Article
Monitoring of the intracellular activation of 5-fluorouracil to deoxyribonucleotides in HT29 human colon cell line: application to modulation of metabolism and cytotoxicity study.
- Published in:
- Fundamental & Clinical Pharmacology, 2000, v. 14, n. 2, p. 147, doi. 10.1111/j.1472-8206.2000.tb00403.x
- By:
- Publication type:
- Article
Setting the Dose of Checkpoint Inhibitors: The Role of Clinical Pharmacology.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Oxaliplatin.
- Published in:
- Clinical Pharmacokinetics, 2000, v. 38, n. 1, p. 1, doi. 10.2165/00003088-200038010-00001
- By:
- Publication type:
- Article
Author Correction: Hyperprogression under Immune Checkpoint Inhibitor: a potential role for germinal immunogenetics.
- Published in:
- 2020
- By:
- Publication type:
- Correction Notice
Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis.
- Published in:
- Nature Medicine, 2011, v. 17, n. 10, p. 1283, doi. 10.1038/nm.2457
- By:
- Publication type:
- Article
Towards Rational Cancer Therapeutics: Optimizing Dosing, Delivery, Scheduling, and Combinations.
- Published in:
- Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 3, p. 458, doi. 10.1002/cpt.1954
- By:
- Publication type:
- Article
Atypical patterns of circadian clock gene expression in human peripheral blood mononuclear cells.
- Published in:
- Journal of Molecular Medicine, 2005, v. 83, n. 9, p. 693, doi. 10.1007/s00109-005-0697-6
- By:
- Publication type:
- Article
Detecting DPD deficiency: when perfect is the enemy of good.
- Published in:
- 2021
- By:
- Publication type:
- letter
Population pharmacokinetic and pharmacodynamic modeling of capecitabine and its metabolites in breast cancer patients.
- Published in:
- 2021
- By:
- Publication type:
- journal article
PIK3CA mutations and specific treatment: do not forget lessons from RAS mutations and EGFR targeting.
- Published in:
- 2020
- By:
- Publication type:
- letter
Pharmacokinetics of trabectedin on hemodialysis: an application for the management of cancer patients with end-stage renal disease.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1363, doi. 10.1007/s00280-011-1718-5
- By:
- Publication type:
- Article
DPD status and fluoropyrimidines-based treatment: high activity matters too.
- Published in:
- 2020
- By:
- Publication type:
- journal article