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Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Integrase Strand Transfer Inhibitors in HIV Therapy.
- Published in:
- Infectious Diseases & Therapy, 2013, v. 2, n. 2, p. 83, doi. 10.1007/s40121-013-0020-8
- By:
- Publication type:
- Article
Implications for the future of the HIV epidemic if drug resistance against dolutegravir cannot occur in first-line therapy.
- Published in:
- Journal of the International AIDS Society, 2015, v. 18, n. 1, p. 1, doi. 10.7448/IAS.18.1.20824
- By:
- Publication type:
- Article
HIV-1 group O integrase displays lower susceptibility to raltegravir and has a different mutational pathway for resistance than HIV-1 group M.
- Published in:
- Journal of the International AIDS Society, 2014, v. 17, p. n/a, doi. 10.7448/IAS.17.4.19738
- By:
- Publication type:
- Article
The R263K mutation in HIV integrase that is selected by dolutegravir may actually prevent clinically relevant resistance to this compound.
- Published in:
- Journal of the International AIDS Society, 2014, v. 17, p. n/a, doi. 10.7448/IAS.17.4.19518
- By:
- Publication type:
- Article
Cenicriviroc blocks HIV entry but does not lead to redistribution of HIV into extracellular space like maraviroc.
- Published in:
- Journal of the International AIDS Society, 2014, v. 17, p. n/a, doi. 10.7448/IAS.17.4.19531
- By:
- Publication type:
- Article
Might dolutegravir be part of a functional cure for HIV?<sup>1</sup>.
- Published in:
- Canadian Journal of Microbiology, 2016, v. 62, n. 5, p. 375, doi. 10.1139/cjm-2015-0725
- By:
- Publication type:
- Article
Antimalarial drugs and their metabolites are potent Zika virus inhibitors.
- Published in:
- Journal of Medical Virology, 2019, v. 91, n. 7, p. 1182, doi. 10.1002/jmv.25440
- By:
- Publication type:
- Article
The antimalarial drug amodiaquine possesses anti‐ZIKA virus activities.
- Published in:
- Journal of Medical Virology, 2018, v. 90, n. 5, p. 796, doi. 10.1002/jmv.25031
- By:
- Publication type:
- Article
Identification of resveratrol analogs as potent anti-dengue agents using a cell-based assay.
- Published in:
- Journal of Medical Virology, 2017, v. 89, n. 3, p. 397, doi. 10.1002/jmv.24660
- By:
- Publication type:
- Article
A resveratrol analog termed 3,3′,4,4′,5,5′-hexahydroxy- trans-stilbene is a potent HIV-1 inhibitor.
- Published in:
- Journal of Medical Virology, 2015, v. 87, n. 12, p. 2054, doi. 10.1002/jmv.24271
- By:
- Publication type:
- Article
Structural Studies of the HIV-1 Integrase Protein: Compound Screening and Characterization of a DNA-Binding Inhibitor.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128310
- By:
- Publication type:
- Article
Dolutegravir reshapes the genetic diversity of HIV-1 reservoirs.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir.
- Published in:
- Retrovirology, 2018, v. 15, n. 1, p. N.PAG, doi. 10.1186/s12977-018-0440-3
- By:
- Publication type:
- Article
HIV drug resistance against strand transfer integrase inhibitors.
- Published in:
- Retrovirology, 2017, v. 14, p. 1, doi. 10.1186/s12977-017-0360-7
- By:
- Publication type:
- Article
Genotypic and Phenotypic Characterization of Replication-Competent HIV-2 Isolated from Controllers and Progressors.
- Published in:
- Viruses (1999-4915), 2023, v. 15, n. 11, p. 2236, doi. 10.3390/v15112236
- By:
- Publication type:
- Article
Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence.
- Published in:
- Viruses (1999-4915), 2015, v. 7, n. 7, p. 3703, doi. 10.3390/v7072790
- By:
- Publication type:
- Article
Is Resistance to Dolutegravir Possible When This Drug Is Used in First-Line Therapy?
- Published in:
- Viruses (1999-4915), 2014, v. 6, n. 9, p. 3377, doi. 10.3390/v6093377
- By:
- Publication type:
- Article
Fitness Impaired Drug Resistant HIV-1 Is Not Compromised in Cell-to-Cell Transmission or Establishment of and Reactivation from Latency.
- Published in:
- Viruses (1999-4915), 2014, v. 6, n. 9, p. 3487, doi. 10.3390/v6093487
- By:
- Publication type:
- Article
Insertion as a Resistance Mechanism Against Integrase Inhibitors in Several Retroviruses.
- Published in:
- 2019
- By:
- Publication type:
- Letter to the Editor
The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation.
- Published in:
- PLoS Pathogens, 2009, v. 5, n. 11, p. 1, doi. 10.1371/journal.ppat.1000650
- By:
- Publication type:
- Article
Two Cases of Viral Re-suppression After M184V + R263K Selection on Dolutegravir/Lamivudine Without Treatment Modification.
- Published in:
- Clinical Infectious Diseases, 2024, v. 79, n. 1, p. 198, doi. 10.1093/cid/ciae006
- By:
- Publication type:
- Article
Exploring an alternative explanation for the second phase of viral decay: Infection of short-lived cells in a drug-limited compartment during HAART.
- Published in:
- PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0198090
- By:
- Publication type:
- Article
Reply to Achieng and Riedel.
- Published in:
- 2019
- By:
- Publication type:
- Letter
Reply to Darcis and Berkhout.
- Published in:
- 2018
- By:
- Publication type:
- Letter
The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors.
- Published in:
- 2018
- By:
- Publication type:
- journal article
HIV-1 Resistance Dynamics in Patients With Virologic Failure to Dolutegravir Maintenance Monotherapy.
- Published in:
- 2018
- By:
- Publication type:
- journal article
What if HIV were unable to develop resistance against a new therapeutic agent?
- Published in:
- 2013
- By:
- Publication type:
- journal article
Progressive emergence of an S153F plus R263K combination of integrase mutations in the proviral DNA of one individual successfully treated with dolutegravir.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Dolutegravir reshapes the genetic diversity of HIV-1 reservoirs.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2018, v. 73, n. 4, p. 1045, doi. 10.1093/jac/dkx475
- By:
- Publication type:
- Article
M184I/V substitutions and E138K/M184I/V double substitutions in HIV reverse transcriptase do not significantly affect the antiviral activity of EFdA.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Polymorphic substitution E157Q in HIV-1 integrase increases R263K-mediated dolutegravir resistance and decreases DNA binding activity.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Development of a G118R mutation in HIV-1 integrase following a switch to dolutegravir monotherapy leading to cross-resistance to integrase inhibitors.
- Published in:
- 2016
- By:
- Publication type:
- journal article
The dual CCR5 and CCR2 inhibitor cenicriviroc does not redistribute HIV into extracellular space: implications for plasma viral load and intracellular DNA decline.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2015, v. 70, n. 3, p. 750, doi. 10.1093/jac/dku451
- By:
- Publication type:
- Article
Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2014, v. 69, n. 10, p. 2733, doi. 10.1093/jac/dku199
- By:
- Publication type:
- Article
Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7.
- Published in:
- European Journal of Immunology, 2009, v. 39, n. 2, p. 527, doi. 10.1002/eji.200838832
- By:
- Publication type:
- Article
Involvement of TBK1 and IKKϵ in lipopolysaccharide-induced activation of the interferon response in primary human macrophages.
- Published in:
- European Journal of Immunology, 2007, v. 37, n. 2, p. 528, doi. 10.1002/eji.200636090
- By:
- Publication type:
- Article
Effect on HIV-1 viral replication capacity of DTG-resistance mutations in NRTI/NNRTI resistant viruses.
- Published in:
- Retrovirology, 2016, v. 13, p. 1, doi. 10.1186/s12977-016-0265-x
- By:
- Publication type:
- Article
The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness.
- Published in:
- Retrovirology, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1742-4690-11-7
- By:
- Publication type:
- Article
Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity.
- Published in:
- Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-73
- By:
- Publication type:
- Article
Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure.
- Published in:
- Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-22
- By:
- Publication type:
- Article
Does antiretroviral treatment change HIV-1 codon usage patterns in its genes: a preliminary bioinformatics study.
- Published in:
- AIDS Research & Therapy, 2017, v. 14, p. 1, doi. 10.1186/s12981-016-0130-y
- By:
- Publication type:
- Article