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Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).
Published in:
Pharmacogenomics Journal, 2014, v. 14, n. 4, p. 336, doi. 10.1038/tpj.2014.2
By:
- Chhibber, A;
- Mefford, J;
- Stahl, E A;
- Pendergrass, S A;
- Baldwin, R M;
- Owzar, K;
- Li, M;
- Winer, E P;
- Hudis, C A;
- Zembutsu, H;
- Kubo, M;
- Nakamura, Y;
- McLeod, H L;
- Ratain, M J;
- Shulman, L N;
- Ritchie, M D;
- Plenge, R M;
- Witte, J S;
- Kroetz, D L
Publication type:
Article
Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice.
Published in:
Pharmacogenomics Journal, 2012, v. 12, n. 2, p. 147, doi. 10.1038/tpj.2010.82
By:
- Crowley, J J;
- Adkins, D E;
- Pratt, A L;
- Quackenbush, C R;
- van den Oord, E J;
- Moy, S S;
- Wilhelmsen, K C;
- Cooper, T B;
- Bogue, M A;
- McLeod, H L;
- Sullivan, P F
Publication type:
Article
Influence of ethnicity on pharmacogenetic variation in the Ghanaian population.
Published in:
Pharmacogenomics Journal, 2009, v. 9, n. 6, p. 373, doi. 10.1038/tpj.2009.28
By:
- Yen-Revollo, J. L.;
- Van Booven, D. J.;
- Peters, E. J.;
- Hoskins, J. M.;
- Engen, R. M .;
- Kannall, H. D.;
- Ofori-Adjei, D.;
- McLeod, H. L.;
- Marsh, S.
Publication type:
Article
Pharmacogenetic analysis of paclitaxel transport and metabolism genes in breast cancer.
Published in:
Pharmacogenomics Journal, 2007, v. 7, n. 5, p. 362, doi. 10.1038/sj.tpj.6500434
By:
- Marsh, S.;
- Somlo, G.;
- Li, X.;
- Frankel, P.;
- King, C. R.;
- Shannon, W. D.;
- McLeod, H. L.;
- Synold, T. W.
Publication type:
Article
CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele.
Published in:
Pharmacogenomics Journal, 2006, v. 6, n. 6, p. 401, doi. 10.1038/sj.tpj.6500390
By:
- Fukami, T.;
- Nakajima, M.;
- Sakai, H.;
- McLeod, H. L.;
- Yokoi, T.
Publication type:
Article
Interethnic variability of ERCC2 polymorphisms.
Published in:
Pharmacogenomics Journal, 2005, v. 5, n. 1, p. 54, doi. 10.1038/sj.tpj.6500283
By:
- King, C. R.;
- Yu, J.;
- Freimuth, R. R.;
- McLeod, H. L.;
- Marsh, S.
Publication type:
Article
Identification and analysis of single-nucleotide polymorphisms in the gemcitabine pharmacologic pathway.
Published in:
Pharmacogenomics Journal, 2004, v. 4, n. 5, p. 307, doi. 10.1038/sj.tpj.6500259
By:
- Fukunaga, A. K.;
- Marsh, S.;
- Murry, D. J.;
- Hurley, T. D.;
- McLeod, H. L.
Publication type:
Article
Ethnic variation in the HER-2 codon 655 genetic polymorphism previously associated with breast cancer.
Published in:
Journal of Human Genetics, 2002, v. 47, n. 4, p. 172, doi. 10.1007/s100380200019
By:
- Ameyaw, M.-M.;
- Tayeb, M.;
- Thornton, N.;
- Folayan, G.;
- Tariq, M.;
- Mobarek, A.;
- Evans, D.A. Price;
- Ofori-Adjei, D.;
- McLeod, H. L.
Publication type:
Article
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia.
Published in:
2000
By:
- McLeod, H L;
- Krynetski, E Y;
- Relling, M V;
- Evans, W E
Publication type:
journal article
PON1 Q192R and Clopidogrel: A Case of the Winner's Curse or Inadequate Replication?
Published in:
Clinical Pharmacology & Therapeutics, 2011, v. 90, n. 6, p. 771, doi. 10.1038/clpt.2011.226
By:
- Talameh, J A;
- McLeod, H L
Publication type:
Article
A Polymorphism in the VKORC1 Regulator Calumenin Predicts Higher Warfarin Dose Requirements in African Americans.
Published in:
Clinical Pharmacology & Therapeutics, 2010, v. 87, n. 4, p. 445, doi. 10.1038/clpt.2009.291
By:
- Voora, D.;
- Koboldt, D. C.;
- King, C. R.;
- Lenzini, P. A.;
- Eby, C. S.;
- Porche-Sorbet, R.;
- Deych, E.;
- Crankshaw, M.;
- Milligan, P. E.;
- McLeod, H. L.;
- Patel, S. R.;
- Cavallari, L. H.;
- Ridker, P. M.;
- Grice, G. R.;
- Miller, R. D.;
- Gage, B. F.
Publication type:
Article
Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of Warfarin.
Published in:
Clinical Pharmacology & Therapeutics, 2008, v. 84, n. 3, p. 326, doi. 10.1038/clpt.2008.10
By:
- Gage, B. F.;
- Eby, C.;
- Johnson, J. A.;
- Deych, E.;
- Rieder, M. J.;
- Ridker, P. M.;
- Milligan, P. E.;
- Grice, G.;
- Lenzini, P.;
- Rettie, A. E.;
- Aquilante, C. L.;
- Grosso, L.;
- Marsh, S.;
- Langaee, T.;
- Farnett, L. E.;
- Voora, D.;
- Veenstra, D. L.;
- Glynn, R. J.;
- Barrett, A.;
- McLeod, H. L.
Publication type:
Article
The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response.
Published in:
Clinical Pharmacology & Therapeutics, 2007, v. 81, n. 3, p. 328, doi. 10.1038/sj.clpt.6100087
By:
- Giacomini, K. M.;
- Brett, C. M.;
- Altman, R. B.;
- Benowitz, N. L.;
- Dolan, M. E.;
- Flockhart, D. A.;
- Johnson, J. A.;
- Hayes, D. F.;
- Klein, T.;
- Krauss, R. M.;
- Kroetz, D. L.;
- McLeod, H. L.;
- Nguyen, A. T.;
- Ratain, M. J.;
- Relling, M. V.;
- Reus, V.;
- Roden, D. M.;
- Schaefer, C. A.;
- Shuldiner, A. R.;
- Skaar, T.
Publication type:
Article
Irinotecan-induced Diarrhea: Functional Significance of the Polymorphic ABCC2 Transporter Protein.
Published in:
Clinical Pharmacology & Therapeutics, 2007, v. 81, n. 1, p. 42, doi. 10.1038/sj.clpt.6100019
By:
- De Jong, F. A.;
- Scott-Horton, T. J.;
- Kroetz, D. L.;
- McLeod, H. L.;
- Friberg, L. E.;
- Mathijssen, R. H.;
- Verweij, J.;
- Marsh, S.;
- Sparreboom, A.
Publication type:
Article
Variants in the SLCO1B3 Gene: Interethnic Distribution and Association with Paclitaxel Pharmacokinetics.
Published in:
Clinical Pharmacology & Therapeutics, 2007, v. 81, n. 1, p. 76, doi. 10.1038/sj.clpt.6100011
By:
- Smith, N. F.;
- Marsh, S.;
- Scott-Horton, T. J.;
- Hamada, A.;
- Mielke, S.;
- Mross, K.;
- Figg, W. D.;
- Verweij, J.;
- McLeod, H. L.;
- Sparreboom, A.
Publication type:
Article
PII-20.
Published in:
Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 2, p. P41, doi. 10.1016/j.clpt.2005.12.145
By:
- de Jong, F. A.;
- Scott-Horton, T.;
- Kroetz, D. L.;
- McLeod, H. L.;
- Friberg, L. E.;
- Mathijssen, R. H.;
- Verweij, J.;
- Sparreboom, A.;
- Marsh, S.
Publication type:
Article
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine.
Published in:
1998
By:
- Black, Alison J.;
- McLeod, Howard L.;
- Black, A J;
- McLeod, H L;
- Capell, H A;
- Powrie, R H;
- Matowe, L K;
- Pritchard, S C;
- Collie-Duguid, E S;
- Reid, D M
Publication type:
journal article
Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer.
Published in:
2011
By:
- Thomas, F;
- Motsinger-Reif, A A;
- Hoskins, J M;
- Dvorak, A;
- Roy, S;
- Alyasiri, A;
- Myerson, R J;
- Fleshman, J W;
- Tan, B R;
- McLeod, H L
Publication type:
journal article
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Rasburicase Therapy in the Context of G6PD Deficiency Genotype.
Published in:
Clinical Pharmacology & Therapeutics, 2014, v. 96, n. 2, p. 169, doi. 10.1038/clpt.2014.97
By:
- Relling, M V;
- McDonagh, E M;
- Chang, T;
- Caudle, K E;
- McLeod, H L;
- Haidar, C E;
- Klein, T;
- Luzzatto, L
Publication type:
Article
The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update.
Published in:
Clinical Pharmacology & Therapeutics, 2014, v. 96, n. 4, p. 423, doi. 10.1038/clpt.2014.125
By:
- Ramsey, L B;
- Johnson, S G;
- Caudle, K E;
- Haidar, C E;
- Voora, D;
- Wilke, R A;
- Maxwell, W D;
- McLeod, H L;
- Krauss, R M;
- Roden, D M;
- Feng, Q;
- Cooper‐DeHoff, R M;
- Gong, L;
- Klein, T E;
- Wadelius, M;
- Niemi, M
Publication type:
Article
Clinical Pharmacogenetics Implementation Consortium Guidelines for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing.
Published in:
Clinical Pharmacology & Therapeutics, 2013, v. 94, n. 6, p. 640, doi. 10.1038/clpt.2013.172
By:
- Caudle, K E;
- Thorn, C F;
- Klein, T E;
- Swen, J J;
- McLeod, H L;
- Diasio, R B;
- Schwab, M
Publication type:
Article
Ready When You Are: Easing Into Preemptive Pharmacogenetics.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 4, p. 412, doi. 10.1038/clpt.2012.144
By:
- He, Y J;
- McLeod, H L
Publication type:
Article
The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 1, p. 112, doi. 10.1038/clpt.2012.57
By:
- Wilke, R A;
- Ramsey, L B;
- Johnson, S G;
- Maxwell, W D;
- McLeod, H L;
- Voora, D;
- Krauss, R M;
- Roden, D M;
- Feng, Q;
- Cooper-DeHoff, R M;
- Gong, L;
- Klein, T E;
- Wadelius, M;
- Niemi, M
Publication type:
Article
Phase I study of AG2034, a targeted GARFT inhibitor, administered once every 3 weeks.
Published in:
2000
By:
- Roberts, John D.;
- Shibata, Stephen;
- Spicer, Darcy V.;
- McLeod, Howard L.;
- Tombes, Mary Beth;
- Kyle, Brenda;
- Carroll, Mary;
- Sheedy, Beth;
- Collier, Mary A.;
- Pithavala, Yazdi K.;
- Paradiso, Linda J.;
- Clendeninn, Neil J.;
- Roberts, J D;
- Shibata, S;
- Spicer, D V;
- McLeod, H L;
- Tombes, M B;
- Kyle, B;
- Carroll, M;
- Sheedy, B
Publication type:
journal article
Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population.
Published in:
British Journal of Clinical Pharmacology, 1996, v. 41, n. 5, p. 425, doi. 10.1046/j.1365-2125.1996.34212.x
By:
- McMURROUGH, J.;
- McLEOD, H. L.
Publication type:
Article
Phase I study of pegylated liposomal doxorubicin and the multidrug-resistance modulator, valspodar.
Published in:
2005
By:
- Fracasso, P. M.;
- Blum, K. A.;
- Ma, M. K.;
- Tan, B. R.;
- Wright, L. P.;
- Goodner, S. A.;
- Fears, C. L.;
- Hou, W.;
- Arquette, M. A.;
- Picus, J.;
- Denes, A.;
- Mortimer, J. E.;
- Ratner, L.;
- Ivy, S. P.;
- McLeod, H. L.
Publication type:
journal article
Unfavourable expression of pharmacologic markers in mucinous colorectal cancer.
Published in:
2005
By:
- Glasgow, S. C.;
- Yu, J.;
- Carvalho, L. P.;
- Shannon, W. D.;
- Fleshman, J. W.;
- McLeod, H. L.
Publication type:
journal article
RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer.
Published in:
2004
By:
- Church, R. D.;
- Yu, J.;
- Fleshman, J. W.;
- Shannon, W. D.;
- Govindan, R.;
- McLeod, H. L.
Publication type:
journal article
CYP3A4 and VDR gene polymorphisms and the risk of prostate cancer in men with benign prostate hyperplasia.
Published in:
2003
By:
- Tayeb, M T;
- Clark, C;
- Haites, N E;
- Sharp, L;
- Murray, G I;
- McLeod, H L
Publication type:
journal article
Colorectal cancer genomics: evidence for multiple genotypes which influence survival.
Published in:
British Journal of Cancer, 2001, v. 85, n. 10, p. 1492, doi. 10.1054/bjoc.2001.2095
By:
- Rooney, P H;
- Boonsong, A;
- McKay, J A;
- Marsh, S;
- Stevenson, D A J;
- Murray, G I;
- Curran, S;
- Haites, N E;
- Cassidy, J;
- McLeod, H L
Publication type:
Article
Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer.
Published in:
British Journal of Cancer, 2001, v. 85, n. 2, p. 242, doi. 10.1054/bjoc.2001.1907
By:
- McFadyen, M C E;
- Cruickshank, M E;
- Miller, I D;
- McLeod, H L;
- Melvin, W T;
- Haites, N E;
- Parkin, D;
- Murray, G I
Publication type:
Article
Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034.
Published in:
British Journal of Cancer, 2001, v. 84, n. 3, p. 308, doi. 10.1054/bjoc.2000.1601
By:
- Bissett, D;
- McLeod, H L;
- Sheedy, B;
- Collier, M;
- Pithavala, Y;
- Paradiso, L;
- Pitsiladis, M;
- Cassidy, J
Publication type:
Article
Comparative genomic hybridization and chromosomal instability in solid tumours.
Published in:
British Journal of Cancer, 1999, v. 80, n. 5/6, p. 862, doi. 10.1038/sj.bjc.6690433
By:
- Rooney, P H;
- Murray, G I;
- Stevenson, D A J;
- Haites, N E;
- Cassidy, J;
- McLeod, H L
Publication type:
Article
Tumour markers of prognosis in colorectal cancer.
Published in:
British Journal of Cancer, 1999, v. 79, n. 2, p. 191, doi. 10.1038/sj.bjc.6690033
By:
- McLeod, H L;
- Murray, G I
Publication type:
Article

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