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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35245-x
By:
- Sivakumar, Smruthy;
- Jin, Dexter X.;
- Tukachinsky, Hanna;
- Murugesan, Karthikeyan;
- McGregor, Kimberly;
- Danziger, Natalie;
- Pavlick, Dean;
- Gjoerup, Ole;
- Ross, Jeffrey S.;
- Harmon, Robert;
- Chung, Jon;
- Decker, Brennan;
- Dennis, Lucas;
- Frampton, Garrett M.;
- Molinero, Luciana;
- Oesterreich, Steffi;
- Venstrom, Jeffrey M.;
- Oxnard, Geoffrey R.;
- Hegde, Priti S.;
- Sokol, Ethan S.
Publication type:
Article
The Molecular, Immunologic, and Clinicodemographic Landscape of MYC-Amplified Advanced Prostate Cancer.
Published in:
Clinical Genitourinary Cancer, 2024, v. 22, n. 1, p. e163, doi. 10.1016/j.clgc.2023.10.008
By:
- Jin, Will H.;
- Liangliang Zhang;
- Graf, Ryon;
- Raskina, Kira;
- Tukachinsky, Hanna;
- Huang, Richard S. P.;
- McGregor, Kimberly;
- Alshalalfa, Mohamed;
- Hougen, Helen Y.;
- Khan, Anwar;
- Punnen, Sanoj;
- Schrock, Alexa B.;
- Venstrom, Jeffrey;
- Mahal, Brandon A.
Publication type:
Article
Translation of the 27-gene immuno-oncology test (IO score) to predict outcomes in immune checkpoint inhibitor treated metastatic urothelial cancer patients.
Published in:
2022
By:
- Seitz, Robert S.;
- Hurwitz, Michael E.;
- Nielsen, Tyler J.;
- Bailey, Daniel B.;
- Varga, Matthew G.;
- Ring, Brian Z.;
- Metts, Carrie F.;
- Schweitzer, Brock L.;
- McGregor, Kimberly;
- Ross, Douglas T.
Publication type:
journal article
Phase I/II study of everolimus combined with mFOLFOX-6 and bevacizumab for first–line treatment of metastatic colorectal cancer.
Published in:
Investigational New Drugs, 2019, v. 37, n. 3, p. 482, doi. 10.1007/s10637-018-0645-2
By:
- Weldon Gilcrease, G.;
- Stenehjem, David D.;
- Wade, Mark L.;
- Weis, John;
- McGregor, Kimberly;
- Whisenant, Jonathan;
- Boucher, Kenneth M.;
- Thorne, Kelli;
- Orgain, Nicole;
- Garrido-Laguna, Ignacio;
- Sharma, Sunil
Publication type:
Article
Investigational Aurora A kinase inhibitor alisertib (MLN8237) as an enteric-coated tablet formulation in non-hematologic malignancies: Phase 1 dose-escalation study.
Published in:
Investigational New Drugs, 2014, v. 32, n. 6, p. 1181, doi. 10.1007/s10637-014-0121-6
By:
- Falchook, Gerald;
- Kurzrock, Razelle;
- Gouw, Launce;
- Hong, David;
- McGregor, Kimberly;
- Zhou, Xiaofei;
- Shi, Hongliang;
- Fingert, Howard;
- Sharma, Sunil
Publication type:
Article
Patients with NSCLCs Harboring Internal Inversions or Deletion Rearrangements of the ALK Gene Have Durable Responses to ALK Kinase Inhibitors.
Published in:
Lung Cancer: Targets & Therapy, 2020, v. 11, p. 33, doi. 10.2147/LCTT.S239675
By:
- Schrock, Alexa B;
- Madison, Russell;
- Rosenzweig, Mark;
- Allen, Justin M;
- Erlich, Rachel L;
- Wang, Siao-Yi;
- Chidiac, Tarek;
- Reddy, Vodur Suresh;
- Riess, Jonathan W;
- Yassa, Ahmet Ersin;
- Shakir, Abdur;
- Miller, Vincent A;
- Alexander, Brian M;
- Venstrom, Jeffrey;
- McGregor, Kimberly;
- Ali, Siraj M
Publication type:
Article
The 27-gene IO score is associated with efficacy of PD-1/L1 inhibitors independent of FGFR expression in a real-world metastatic urothelial carcinoma cohort.
Published in:
Cancer Immunology, Immunotherapy, 2023, v. 72, n. 7, p. 2075, doi. 10.1007/s00262-023-03401-x
By:
- Nielsen, Tyler J.;
- Varga, Matthew G.;
- Cronister, Catherine T.;
- Ring, Brian Z.;
- Seitz, Robert S.;
- Ross, Douglas T.;
- Schweitzer, Brock L.;
- McGregor, Kimberly
Publication type:
Article
Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.
Published in:
Cancer Medicine, 2021, v. 10, n. 1, p. 53, doi. 10.1002/cam4.3550
By:
- Sivapiragasam, Abirami;
- Ashok Kumar, Prashanth;
- Sokol, Ethan S.;
- Albacker, Lee A.;
- Killian, Jonathan K.;
- Ramkissoon, Shakti H.;
- Huang, Richard S. P.;
- Severson, Eric A.;
- Brown, Charlotte A.;
- Danziger, Natalie;
- McGregor, Kimberly;
- Ross, Jeffrey S.
Publication type:
Article
An open‐label, dose‐ranging study of Rolontis, a novel long‐acting myeloid growth factor, in breast cancer.
Published in:
Cancer Medicine, 2018, v. 7, n. 5, p. 1660, doi. 10.1002/cam4.1388
By:
- Vacirca, Jeffrey L.;
- Chan, Arlene;
- Mezei, Klára;
- Adoo, Clarence S.;
- Pápai, Zsuzsanna;
- McGregor, Kimberly;
- Okera, Meena;
- Horváth, Zsolt;
- Landherr, László;
- Hanslik, Jerzy;
- Hager, Steven J.;
- Ibrahim, Emad N.;
- Rostom, Makharadze;
- Bhat, Gajanan;
- Choi, Mi Rim;
- Reddy, Guru;
- Tedesco, Karen L.;
- Agajanian, Richy;
- Láng, István;
- Schwartzberg, Lee S.
Publication type:
Article
A Phase 1 dose-escalation study of disulfiram and copper gluconate in patients with advanced solid tumors involving the liver using S-glutathionylation as a biomarker.
Published in:
BMC Cancer, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12885-021-08242-4
By:
- Kelley, Kristen C.;
- Grossman, Kenneth F.;
- Brittain-Blankenship, Mary;
- Thorne, Kelli M.;
- Akerley, Wallace L.;
- Terrazas, Moises C.;
- Kosak, Ken M.;
- Boucher, Kenneth M.;
- Buys, Saundra S.;
- McGregor, Kimberly A.;
- Werner, Theresa L.;
- Agarwal, Neeraj;
- Weis, John R.;
- Sharma, Sunil;
- Ward, John H.;
- Kennedy, Thomas P.;
- Sborov, Douglas W.;
- Shami, Paul J.
Publication type:
Article
A Phase 1 dose-escalation study of disulfiram and copper gluconate in patients with advanced solid tumors involving the liver using S-glutathionylation as a biomarker.
Published in:
2021
By:
- Kelley, Kristen C.;
- Grossman, Kenneth F.;
- Brittain-Blankenship, Mary;
- Thorne, Kelli M.;
- Akerley, Wallace L.;
- Terrazas, Moises C.;
- Kosak, Ken M.;
- Boucher, Kenneth M.;
- Buys, Saundra S.;
- McGregor, Kimberly A.;
- Werner, Theresa L.;
- Agarwal, Neeraj;
- Weis, John R.;
- Sharma, Sunil;
- Ward, John H.;
- Kennedy, Thomas P.;
- Sborov, Douglas W.;
- Shami, Paul J.
Publication type:
journal article
Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix.
Published in:
2020
By:
- Honglin Jiang;
- Torphy, Robert J.;
- Steiger, Katja;
- Hongo, Henry;
- Ritchie, Alexa J.;
- Kriegsmann, Mark;
- Horst, David;
- Umetsu, Sarah E.;
- Joseph, Nancy M.;
- McGregor, Kimberly;
- Pishvaian, Michael J.;
- Blais, Edik M.;
- Lu, Brian;
- Mingyu Li;
- Hollingsworth, Michael;
- Stashko, Connor;
- Volmar, Keith;
- Jen Jen Yeh;
- Weaver, Valerie M.;
- Wang, Zhen J.
Publication type:
journal article
Clinicopathologic, genomic and protein expression characterization of 356 ROS1 fusion driven solid tumors cases.
Published in:
International Journal of Cancer, 2021, v. 148, n. 7, p. 1778, doi. 10.1002/ijc.33447
By:
- Huang, Richard S. P.;
- Haberberger, James;
- Sokol, Ethan;
- Schrock, Alexa B.;
- Danziger, Natalie;
- Madison, Russell;
- Trabucco, Sally;
- Jin, Dexter;
- Pavlick, Dean;
- Ramanan, Vivek;
- Hole, Kanchan;
- McGregor, Kimberly;
- Venstrom, Jeffrey;
- Ross, Jeffrey S.
Publication type:
Article
Genomic Profiling of Circulating Tumor DNA From Cerebrospinal Fluid to Guide Clinical Decision Making for Patients With Primary and Metastatic Brain Tumors.
Published in:
Frontiers in Neurology, 2020, v. 11, p. N.PAG, doi. 10.3389/fneur.2020.544680
By:
- Ramkissoon, Lori A.;
- Pegram, Worthy;
- Haberberger, James;
- Danziger, Natalie;
- Lesser, Glenn;
- Strowd, Roy;
- Dahiya, Sonika;
- Cummings, Thomas J.;
- Bi, Wenya Linda;
- Abedalthagafi, Malak;
- Sathyan, Pratheesh;
- McGregor, Kimberly;
- Reddy, Prasanth;
- Severson, Eric;
- Williams, Erik;
- Lin, Douglas;
- Edgerly, Claire;
- Huang, Richard S. P.;
- Hemmerich, Amanda;
- Creeden, James
Publication type:
Article
Potential pathogenic germline variant reporting from tumor comprehensive genomic profiling complements classic approaches to germline testing.
Published in:
NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00429-1
By:
- Tung, Nadine;
- Dougherty, Kali Chatham;
- Gatof, Emily Stern;
- DeLeonardis, Kim;
- Hogan, Lauren;
- Tukachinsky, Hanna;
- Gornstein, Erica;
- Oxnard, Geoffrey R.;
- McGregor, Kimberly;
- Keller, Rachel B.
Publication type:
Article
Potential pathogenic germline variant reporting from tumor comprehensive genomic profiling complements classic approaches to germline testing.
Published in:
NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00429-1
By:
- Tung, Nadine;
- Dougherty, Kali Chatham;
- Gatof, Emily Stern;
- DeLeonardis, Kim;
- Hogan, Lauren;
- Tukachinsky, Hanna;
- Gornstein, Erica;
- Oxnard, Geoffrey R.;
- McGregor, Kimberly;
- Keller, Rachel B.
Publication type:
Article
Homologous Recombination Deficiency: Concepts, Definitions, and Assays.
Published in:
Oncologist, 2022, v. 27, n. 3, p. 167, doi. 10.1093/oncolo/oyab053
By:
- Stewart, Mark D;
- Vega, Diana Merino;
- Arend, Rebecca C;
- Baden, Jonathan F;
- Barbash, Olena;
- Beaubier, Nike;
- Collins, Grace;
- French, Tim;
- Ghahramani, Negar;
- Hinson, Patsy;
- Jelinic, Petar;
- Marton, Matthew J;
- McGregor, Kimberly;
- Parsons, Jerod;
- Ramamurthy, Lakshman;
- Sausen, Mark;
- Sokol, Ethan S;
- Stenzinger, Albrecht;
- Stires, Hillary;
- Timms, Kirsten M
Publication type:
Article
Clinicopathologic and Genomic Landscape of Breast Carcinoma Brain Metastases.
Published in:
Oncologist, 2021, v. 26, n. 10, p. 835, doi. 10.1002/onco.13855
By:
- Huang, Richard S.P.;
- Haberberger, James;
- McGregor, Kimberly;
- Mata, Douglas A.;
- Decker, Brennan;
- Hiemenz, Matthew C.;
- Lechpammer, Mirna;
- Danziger, Natalie;
- Schiavone, Kelsie;
- Creeden, James;
- Graf, Ryon P.;
- Strowd, Roy;
- Lesser, Glenn J.;
- Razis, Evangelia D.;
- Bartsch, Rupert;
- Giannoudis, Athina;
- Bhogal, Talvinder;
- Lin, Nancy U.;
- Pusztai, Lajos;
- Ross, Jeffrey S.
Publication type:
Article
Comparative Genomic Analysis of Intrahepatic Cholangiocarcinoma: Biopsy Type, Ancestry, and Testing Patterns.
Published in:
Oncologist, 2021, v. 26, n. 9, p. 787, doi. 10.1002/onco.13844
By:
- Israel, Mason A.;
- Danziger, Natalie;
- McGregor, Kimberly A.;
- Murugesan, Karthikeyan;
- Gjoerup, Ole;
- Sokol, Ethan S.;
- Tukachinsky, Hanna;
- Kurzrock, Razelle;
- Kato, Shumei;
- Sicklick, Jason K.;
- Nimeiri, Halla S.;
- Oxnard, Geoffrey R.;
- Ross, Jeffrey S.
Publication type:
Article
Genomic profiling and comparative analysis of male versus female metastatic breast cancer across subtypes.
Published in:
Breast Cancer Research, 2024, v. 26, n. 1, p. 1, doi. 10.1186/s13058-024-01872-z
By:
- Kadamkulam Syriac, Arun;
- Nandu, Nitish Singh;
- Clark, Allison;
- Tavallai, Mehrad;
- Jin, Dexter X.;
- Sokol, Ethan;
- McGregor, Kimberly;
- Ross, Jeffrey S.;
- Danziger, Natalie;
- Leone, Jose Pablo
Publication type:
Article

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