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Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib.
Published in:
International Journal of Hematology, 2013, v. 98, n. 1, p. 66, doi. 10.1007/s12185-013-1367-z
By:
- Nakamura, Shingen;
- Miki, Hirokazu;
- Kido, Shinsuke;
- Nakano, Ayako;
- Hiasa, Masahiro;
- Oda, Asuka;
- Amou, Hiroe;
- Watanabe, Keiichiro;
- Harada, Takeshi;
- Fujii, Shiro;
- Takeuchi, Kyoko;
- Kagawa, Kumiko;
- Ozaki, Shuji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Targeting myeloma-osteoclast interaction with Vγ9Vδ2 T cells.
Published in:
2011
By:
- Cui, Qu;
- Shibata, Hironobu;
- Oda, Asuka;
- Amou, Hiroe;
- Nakano, Ayako;
- Yata, Kenichiro;
- Hiasa, Masahiro;
- Watanabe, Keiichiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Harada, Takeshi;
- Fujii, Shiro;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Ozaki, Shuji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
journal article
Delayed treatment with vitamin C and N-acetyl-L-cysteine protects Schwann cells without compromising the anti-myeloma activity of bortezomib.
Published in:
2011
By:
- Nakano, Ayako;
- Abe, Masahiro;
- Oda, Asuka;
- Amou, Hiroe;
- Hiasa, Masahiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Harada, Takeshi;
- Fujii, Shirou;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Watanabe, Takashi;
- Ozaki, Shuji;
- Matsumoto, Toshio
Publication type:
journal article
Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma.
Published in:
2009
By:
- Kitazoe, Ken-ichi;
- Abe, Masahiro;
- Hiasa, Masahiro;
- Oda, Asuka;
- Amou, Hiroe;
- Harada, Takeshi;
- Nakano, Ayako;
- Takeuchi, Kyoko;
- Hashimoto, Toshihiro;
- Ozaki, Shuji;
- Matsumoto, Toshio
Publication type:
journal article
Crosstalk Between Sensory Nerves and Cancer in Bone.
Published in:
Current Osteoporosis Reports, 2018, v. 16, n. 6, p. 648, doi. 10.1007/s11914-018-0489-x
By:
- Yoneda, Toshiyuki;
- Hiasa, Masahiro;
- Okui, Tatsuo
Publication type:
Article
Class 1 HDAC and HDAC6 inhibition inversely regulates CD38 induction in myeloma cells via interferon‐α and ATRA.
Published in:
British Journal of Haematology, 2019, v. 185, n. 5, p. 969, doi. 10.1111/bjh.15673
By:
- Bat‐Erdene, Ariunzaya;
- Nakamura, Shingen;
- Oda, Asuka;
- Iwasa, Masami;
- Teramachi, Jumpei;
- Ashtar, Mohannad;
- Harada, Takeshi;
- Miki, Hirokazu;
- Tenshin, Hirofumi;
- Hiasa, Masahiro;
- Fujii, Shiro;
- Sogabe, Kimiko;
- Oura, Masahiro;
- Udaka, Kengo;
- Kagawa, Kumiko;
- Yoshida, Sumiko;
- Aihara, Ken‐ichi;
- Kurahashi, Kiyoe;
- Endo, Itsuro;
- Abe, Masahiro
Publication type:
Article
Pim‐2 is a critical target for treatment of osteoclastogenesis enhanced in myeloma.
Published in:
British Journal of Haematology, 2018, v. 180, n. 4, p. 581, doi. 10.1111/bjh.14388
By:
- Teramachi, Jumpei;
- Hiasa, Masahiro;
- Oda, Asuka;
- Harada, Takeshi;
- Nakamura, Shingen;
- Amachi, Ryota;
- Tenshin, Hirofumi;
- Iwasa, Masami;
- Fujii, Shiro;
- Kagawa, Kumiko;
- Miki, Hirokazu;
- Kurahashi, Kiyoe;
- Yoshida, Sumiko;
- Endo, Itsuro;
- Haneji, Tatsuji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Unique anti‐myeloma activity by thiazolidine‐2,4‐dione compounds with Pim inhibiting activity.
Published in:
British Journal of Haematology, 2018, v. 180, n. 2, p. 246, doi. 10.1111/bjh.15033
By:
- Fujii, Shiro;
- Nakamura, Shingen;
- Oda, Asuka;
- Miki, Hirokazu;
- Tenshin, Hirofumi;
- Teramachi, Jumpei;
- Hiasa, Masahiro;
- Bat‐Erdene, Ariunzaya;
- Maeda, Yusaku;
- Oura, Masahiro;
- Takahashi, Mamiko;
- Iwasa, Masami;
- Endo, Itsuro;
- Yoshida, Sumiko;
- Aihara, Ken‐ichi;
- Kurahashi, Kiyoe;
- Harada, Takeshi;
- Kagawa, Kumiko;
- Nakao, Michiyasu;
- Sano, Shigeki
Publication type:
Article
TGF-β Inhibition Restores Terminal Osteoblast Differentiation to Suppress Myeloma Growth.
Published in:
PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009870
By:
- Takeuchi, Kyoko;
- Abe, Masahiro;
- Hiasa, Masahiro;
- Oda, Asuka;
- Amou, Hiroe;
- Kido, Shinsuke;
- Harada, Takeshi;
- Tanaka, Osamu;
- Miki, Hirokazu;
- Nakamura, Shingen;
- Nakano, Ayako;
- Kagawa, Kumiko;
- Yata, Kenichiro;
- Ozaki, Shuji;
- Matsumoto, Toshio
Publication type:
Article
Myeloma–Bone Interaction: A Vicious Cycle via TAK1–PIM2 Signaling.
Published in:
Cancers, 2021, v. 13, n. 17, p. 4441, doi. 10.3390/cancers13174441
By:
- Harada, Takeshi;
- Hiasa, Masahiro;
- Teramachi, Jumpei;
- Abe, Masahiro
Publication type:
Article
The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis: Suppressive Effects of Febuxostat.
Published in:
Cancers, 2020, v. 12, n. 4, p. 929, doi. 10.3390/cancers12040929
By:
- Ashtar, Mohannad;
- Tenshin, Hirofumi;
- Teramachi, Jumpei;
- Bat-Erdene, Ariunzaya;
- Hiasa, Masahiro;
- Oda, Asuka;
- Tanimoto, Kotaro;
- Shimizu, So;
- Higa, Yoshiki;
- Harada, Takeshi;
- Oura, Masahiro;
- Sogabe, Kimiko;
- Nakamura, Shingen;
- Fujii, Shiro;
- Sumitani, Ryohei;
- Miki, Hirokazu;
- Udaka, Kengo;
- Takahashi, Mamiko;
- Kagawa, Kumiko;
- Endo, Itsuro
Publication type:
Article
P-005: Novel strategy of elotuzumab and zoledronic acid with Th1-like γδT cells against myeloma.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S41, doi. 10.1016/S2152-2650(21)02139-X
By:
- Takeshi Harada;
- Yusuke Inoue;
- Hirofumi Tenshin;
- Asuka Oda;
- Ryohei Sumitani;
- Masahiro Oura;
- Kimiko Sogabe;
- Shiro Fujii;
- Shingen Nakamura;
- Hirokazu Miki;
- Masahiro Hiasa;
- Jumpei Teramachi;
- Masahiro Abe
Publication type:
Article
A progressive auto-amplification loop in TAK1 expression and activation in myeloma cells.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e111, doi. 10.1016/j.clml.2019.09.183
By:
- Teramachi, Jumpei;
- Shimizu, So;
- Harada, Takeshi;
- Tenshin, Hirofumi;
- Oda, Asuka;
- Bat-Erdene, Ariunzaya;
- Hiasa, Masahiro;
- Tanimoto, Kotaro;
- Endo, Itsuro;
- Matsumoto, Toshio;
- Tanaka, Eiji;
- Abe, Masahiro
Publication type:
Article
Bone–fat linkage via interleukin-11 in response to mechanical loading.
Published in:
Journal of Bone & Mineral Metabolism, 2024, v. 42, n. 4, p. 447, doi. 10.1007/s00774-023-01493-0
By:
- Hiasa, Masahiro;
- Endo, Itsuro;
- Matsumoto, Toshio
Publication type:
Article
Cancer–nerve interplay in cancer progression and cancer-induced bone pain.
Published in:
Journal of Bone & Mineral Metabolism, 2023, v. 41, n. 3, p. 415, doi. 10.1007/s00774-023-01401-6
By:
- Yoneda, Toshiyuki;
- Hiasa, Masahiro;
- Okui, Tatsuo;
- Hata, Kenji
Publication type:
Article
Myeloma bone disease: pathogenesis and management in the era of new anti-myeloma agents.
Published in:
Journal of Bone & Mineral Metabolism, 2023, v. 41, n. 3, p. 388, doi. 10.1007/s00774-023-01403-4
By:
- Teramachi, Jumpei;
- Miki, Hirokazu;
- Nakamura, Shingen;
- Hiasa, Masahiro;
- Harada, Takeshi;
- Abe, Masahiro
Publication type:
Article
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2.
Published in:
Antioxidants, 2023, v. 12, n. 1, p. 133, doi. 10.3390/antiox12010133
By:
- Higa, Yoshiki;
- Hiasa, Masahiro;
- Tenshin, Hirofumi;
- Nakaue, Emiko;
- Tanaka, Mariko;
- Kim, Sooha;
- Nakagawa, Motosumi;
- Shimizu, So;
- Tanimoto, Kotaro;
- Teramachi, Jumpei;
- Harada, Takeshi;
- Oda, Asuka;
- Oura, Masahiro;
- Sogabe, Kimiko;
- Hara, Tomoyo;
- Sumitani, Ryohei;
- Maruhashi, Tomoko;
- Yamagami, Hiroki;
- Endo, Itsuro;
- Matsumoto, Toshio
Publication type:
Article
Lactate secreted via MCT4 from bone-colonizing breast cancer excites sensory neurons via GPR81.
Published in:
International Journal of Oncology, 2023, v. 62, n. 3, p. N.PAG, doi. 10.3892/ijo.2023.5487
By:
- Okui, Tatsuo;
- Hiasa, Masahiro;
- Hasegawa, Kazuaki;
- Nakamura, Tomoya;
- Ono, Kisho;
- Ibaragi, Soichiro;
- Kanno, Takahiro;
- Sasaki, Akira;
- Yoneda, Toshiyuki
Publication type:
Article
Ex vivo expansion and activation of Vγ9Vδ2 T cells by CELMoDs in combination with zoledronic acid.
Published in:
International Journal of Hematology, 2024, v. 119, n. 6, p. 626, doi. 10.1007/s12185-024-03763-7
By:
- Inoue, Yusuke;
- Oda, Asuka;
- Maeda, Yusaku;
- Sumitani, Ryohei;
- Oura, Masahiro;
- Sogabe, Kimiko;
- Maruhashi, Tomoko;
- Takahashi, Mamiko;
- Fujii, Shiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Hiasa, Masahiro;
- Teramachi, Jumpei;
- Harada, Takeshi;
- Abe, Masahiro
Publication type:
Article
Mechanisms of preferential bone formation in myeloma bone lesions by proteasome inhibitors.
Published in:
International Journal of Hematology, 2023, v. 118, n. 1, p. 88, doi. 10.1007/s12185-023-03601-2
By:
- Nakaue, Emiko;
- Teramachi, Jumpei;
- Tenshin, Hirofumi;
- Hiasa, Masahiro;
- Harada, Takeshi;
- Oda, Asuka;
- Inoue, Yusuke;
- Shimizu, So;
- Higa, Yoshiki;
- Sogabe, Kimiko;
- Oura, Masahiro;
- Hara, Tomoyo;
- Sumitani, Ryohei;
- Maruhashi, Tomoko;
- Yamagami, Hiroki;
- Endo, Itsuro;
- Tanaka, Eiji;
- Abe, Masahiro
Publication type:
Article
TGF‐β‐activated kinase‐1 inhibitor LL‐Z1640‐2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF‐α and RANKL expression.
Published in:
Clinical & Translational Immunology, 2022, v. 11, n. 1, p. 1, doi. 10.1002/cti2.1371
By:
- Tenshin, Hirofumi;
- Teramachi, Jumpei;
- Ashtar, Mohannad;
- Hiasa, Masahiro;
- Inoue, Yusuke;
- Oda, Asuka;
- Tanimoto, Kotaro;
- Shimizu, So;
- Higa, Yoshiki;
- Harada, Takeshi;
- Oura, Masahiro;
- Sogabe, Kimiko;
- Hara, Tomoyo;
- Sumitani, Ryohei;
- Maruhashi, Tomoko;
- Sebe, Mayu;
- Tsutsumi, Rie;
- Sakaue, Hiroshi;
- Endo, Itsuro;
- Matsumoto, Toshio
Publication type:
Article
KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts.
Published in:
British Journal of Haematology, 2011, v. 155, n. 3, p. 328, doi. 10.1111/j.1365-2141.2011.08844.x
By:
- Miki, Hirokazu;
- Ozaki, Shuji;
- Nakamura, Shingen;
- Oda, Asuka;
- Amou, Hiroe;
- Ikegame, Akishige;
- Watanabe, Keiichiro;
- Hiasa, Masahiro;
- Cui, Qu;
- Harada, Takeshi;
- Fujii, Shiro;
- Nakano, Ayako;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Yata, Ken-ichiro;
- Sakai, Akira;
- Abe, Masahiro;
- Matsumoto, Toshio
Publication type:
Article
Inflammatory Cytokine-Induced Muscle Atrophy and Weakness Can Be Ameliorated by an Inhibition of TGF-β-Activated Kinase-1.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 5715, doi. 10.3390/ijms25115715
By:
- Kanai, Mai;
- Ganbaatar, Byambasuren;
- Endo, Itsuro;
- Ohnishi, Yukiyo;
- Teramachi, Jumpei;
- Tenshin, Hirofumi;
- Higa, Yoshiki;
- Hiasa, Masahiro;
- Mitsui, Yukari;
- Hara, Tomoyo;
- Masuda, Shiho;
- Yamagami, Hiroki;
- Yamaguchi, Yuki;
- Aihara, Ken-ichi;
- Sebe, Mayu;
- Tsutsumi, Rie;
- Sakaue, Hiroshi;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Persistent Activation of Calcium‐Sensing Receptor Suppresses Bone Turnover, Increases Microcracks, and Decreases Bone Strength.
Published in:
JBMR Plus, 2019, v. 3, n. 7, p. N.PAG, doi. 10.1002/jbm4.10182
By:
- Dong, Bingzi;
- Endo, Itsuro;
- Ohnishi, Yukiyo;
- Mitsui, Yukari;
- Kurahashi, Kiyoe;
- Kanai, Mai;
- Hiasa, Masahiro;
- Teramachi, Jumpei;
- Tenshin, Hirofumi;
- Fukumoto, Seiji;
- Abe, Masahiro;
- Matsumoto, Toshio
Publication type:
Article
Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging.
Published in:
Aging Cell, 2017, v. 16, n. 3, p. 551, doi. 10.1111/acel.12586
By:
- Davis, Hannah M.;
- Pacheco‐Costa, Rafael;
- Atkinson, Emily G.;
- Brun, Lucas R.;
- Gortazar, Arancha R.;
- Harris, Julia;
- Hiasa, Masahiro;
- Bolarinwa, Surajudeen A.;
- Yoneda, Toshiyuki;
- Ivan, Mircea;
- Bruzzaniti, Angela;
- Bellido, Teresita;
- Plotkin, Lilian I.
Publication type:
Article

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