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Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 14, p. 3392, doi. 10.3390/ijms20143392
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- Article
Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1.
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- International Journal of Molecular Sciences, 2016, v. 17, n. 2, p. 213, doi. 10.3390/ijms17020213
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- Article
A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 11, p. 27561, doi. 10.3390/ijms161126047
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- Article
Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches.
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- International Journal of Molecular Sciences, 2014, v. 15, n. 6, p. 10271, doi. 10.3390/ijms150610271
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- Article
Structural characterization of the heme-based oxygen sensor, AfGcHK, its interactions with the cognate response regulator, and their combined mechanism of action in a bacterial two-component signaling system.
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- Proteins, 2016, v. 84, n. 10, p. 1375, doi. 10.1002/prot.25083
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- Article
Highly conserved nucleotide phosphatase essential for membrane lipid homeostasis in Streptococcus pneumoniae.
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- Molecular Microbiology, 2016, v. 101, n. 1, p. 12, doi. 10.1111/mmi.13312
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- Article
The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 6, p. 448, doi. 10.1002/em.20642
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- Article
Mutagenic Potential of Nitrenium Ions of Nitrobenzanthrones: Correlation Between Theory and Experiment.
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- Environmental & Molecular Mutagenesis, 2008, v. 49, n. 8, p. 659, doi. 10.1002/em.20411
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- Article
Case report: A rare variant m.4135T>C in the MT-ND1 gene leads to Leber hereditary optic neuropathy and altered respiratory chain supercomplexes.
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- Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1182288
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- Article
DNA polymerase β catalytic efficiency mirrors the Asn279–dCTP H-bonding strength
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- FEBS Letters, 2007, v. 581, n. 4, p. 775, doi. 10.1016/j.febslet.2007.01.042
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- Article
Glycosylation Protects Proteins against Free Radicals Generated from Toxic Xenobiotics.
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- Toxicological Sciences, 2010, v. 117, n. 2, p. 359, doi. 10.1093/toxsci/kfq206
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- Article