Found: 21

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  • Epigenetic Modulation of Gremlin-1/NOTCH Pathway in Experimental Crescentic Immune-Mediated Glomerulonephritis.

    Published in:
    Pharmaceuticals (14248247), 2022, v. 15, n. 2, p. 121, doi. 10.3390/ph15020121
    By:
    • Tejedor-Santamaria, Lucia;
    • Morgado-Pascual, Jose Luis;
    • Marquez-Exposito, Laura;
    • Suarez-Alvarez, Beatriz;
    • Rodrigues-Diez, Raul R.;
    • Tejera-Muñoz, Antonio;
    • Marchant, Vanessa;
    • Mezzano, Sergio;
    • Lopez-Larrea, Carlos;
    • Sola, Anna;
    • Fernandez-Juarez, Gema Maria;
    • Ortiz, Alberto;
    • Rayego-Mateos, Sandra;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Novel Aspects of the Immune Response Involved in the Peritoneal Damage in Chronic Kidney Disease Patients under Dialysis.

    Published in:
    International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5763, doi. 10.3390/ijms24065763
    By:
    • Trionfetti, Flavia;
    • Marchant, Vanessa;
    • González-Mateo, Guadalupe T.;
    • Kawka, Edyta;
    • Márquez-Expósito, Laura;
    • Ortiz, Alberto;
    • López-Cabrera, Manuel;
    • Ruiz-Ortega, Marta;
    • Strippoli, Raffaele
    Publication type:
    Article

  • Molecular Mechanisms of Kidney Injury and Repair.

    Published in:
    International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1542, doi. 10.3390/ijms23031542
    By:
    • Rayego-Mateos, Sandra;
    • Marquez-Expósito, Laura;
    • Rodrigues-Diez, Raquel;
    • Sanz, Ana B.;
    • Guiteras, Roser;
    • Doladé, Nuria;
    • Rubio-Soto, Irene;
    • Manonelles, Anna;
    • Codina, Sergi;
    • Ortiz, Alberto;
    • Cruzado, Josep M.;
    • Ruiz-Ortega, Marta;
    • Sola, Anna
    Publication type:
    Article

  • CCN2 Increases TGF-β Receptor Type II Expression in Vascular Smooth Muscle Cells: Essential Role of CCN2 in the TGF-β Pathway Regulation.

    Published in:
    International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 375, doi. 10.3390/ijms23010375
    By:
    • Tejera-Muñoz, Antonio;
    • Marquez-Exposito, Laura;
    • Tejedor-Santamaría, Lucía;
    • Rayego-Mateos, Sandra;
    • Orejudo, Macarena;
    • Suarez-Álvarez, Beatriz;
    • López-Larrea, Carlos;
    • Ruíz-Ortega, Marta;
    • Rodrigues-Díez, Raúl R.
    Publication type:
    Article

  • Could IL-17A Be a Novel Therapeutic Target in Diabetic Nephropathy?

    Published in:
    Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 272, doi. 10.3390/jcm9010272
    By:
    • Lavoz, Carolina;
    • Rayego-Mateos, Sandra;
    • Orejudo, Macarena;
    • Opazo-Ríos, Lucas;
    • Marchant, Vanessa;
    • Marquez-Exposito, Laura;
    • Tejera-Muñoz, Antonio;
    • Navarro-González, Juan F.;
    • Droguett, Alejandra;
    • Ortiz, Alberto;
    • Egido, Jesús;
    • Mezzano, Sergio;
    • Rodrigues-Diez, Raúl R.;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes.

    Published in:
    Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.662020
    By:
    • Marquez-Exposito, Laura;
    • Tejedor-Santamaria, Lucia;
    • Santos-Sanchez, Laura;
    • Valentijn, Floris A.;
    • Cantero-Navarro, Elena;
    • Rayego-Mateos, Sandra;
    • Rodrigues-Diez, Raul R.;
    • Tejera-Muñoz, Antonio;
    • Marchant, Vanessa;
    • Sanz, Ana B.;
    • Ortiz, Alberto;
    • Goldschmeding, Roel;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Interleukin-17A: Potential mediator and therapeutic target in hypertension.

    Published in:
    Nefrologia, 2021, v. 41, n. 3, p. 244, doi. 10.1016/j.nefro.2020.11.009
    By:
    • Rodrigues-Diez, Raúl R.;
    • Tejera-Muñoz, Antonio;
    • Orejudo, Macarena;
    • Marquez-Exposito, Laura;
    • Santos-Sanchez, Laura;
    • Rayego-Mateos, Sandra;
    • Cantero-Navarro, Elena;
    • Tejedor-Santamaria, Lucia;
    • Marchant, Vanessa;
    • Ortiz, Alberto;
    • Egido, Jesús;
    • Mezzano, Sergio;
    • Selgas, Rafael;
    • Navarro-González, Juan F.;
    • Valdivielso, Jose M.;
    • Lavoz, Carolina;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Análisis de la vía Notch como una posible diana terapéutica en la patología renal.

    Published in:
    Nefrologia, 2018, v. 38, n. 5, p. 466, doi. 10.1016/j.nefro.2017.11.027
    By:
    • Rodrigues-Diez, Raúl R.;
    • Marquez-Exposito, Laura;
    • Cantero-Navarro, Elena;
    • Poveda, Jonay;
    • Rayego-Mateos, Sandra;
    • Morgado-Pascual, José Luis;
    • Orejudo, Macarena;
    • Ruiz-Ortega, Marta;
    • Lavoz, Carolina;
    • Mezzano, Sergio;
    • Fierro-Fernández, Marta
    Publication type:
    Article

  • CCN2 Binds to Tubular Epithelial Cells in the Kidney.

    Published in:
    Biomolecules (2218-273X), 2022, v. 12, n. 2, p. 252, doi. 10.3390/biom12020252
    By:
    • Rayego-Mateos, Sandra;
    • Morgado-Pascual, José Luis;
    • Lavoz, Carolina;
    • Rodrigues-Díez, Raúl R.;
    • Márquez-Expósito, Laura;
    • Tejera-Muñoz, Antonio;
    • Tejedor-Santamaría, Lucía;
    • Rubio-Soto, Irene;
    • Marchant, Vanessa;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • IL-17A as a Potential Therapeutic Target for Patients on Peritoneal Dialysis.

    Published in:
    Biomolecules (2218-273X), 2020, v. 10, n. 10, p. 1361, doi. 10.3390/biom10101361
    By:
    • Marchant, Vanessa;
    • Tejera-Muñoz, Antonio;
    • Marquez-Expósito, Laura;
    • Rayego-Mateos, Sandra;
    • Rodrigues-Diez, Raul R.;
    • Tejedor, Lucia;
    • Santos-Sanchez, Laura;
    • Egido, Jesús;
    • Ortiz, Alberto;
    • Valdivielso, Jose M.;
    • Fraser, Donald J.;
    • López-Cabrera, Manuel;
    • Selgas, Rafael;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Deletion of delta‐like 1 homologue accelerates renal inflammation by modulating the Th17 immune response.

    Published in:
    FASEB Journal, 2021, v. 35, n. 1, p. 1, doi. 10.1096/fj.201903131R
    By:
    • Marquez‐Exposito, Laura;
    • Rodrigues‐Diez, Raul R.;
    • Rayego‐Mateos, Sandra;
    • Fierro‐Fernandez, Marta;
    • Rodrigues‐Diez, Raquel;
    • Orejudo, Macarena;
    • Santos‐Sanchez, Laura;
    • Blanco, Eva Maria;
    • Laborda, Jorge;
    • Mezzano, Sergio;
    • Lamas, Santiago;
    • Lavoz, Carolina;
    • Ruiz‐Ortega, Marta
    Publication type:
    Article

  • MiR‐9‐5p protects from kidney fibrosis by metabolic reprogramming.

    Published in:
    FASEB Journal, 2020, v. 34, n. 1, p. 410, doi. 10.1096/fj.201901599RR
    By:
    • Fierro‐Fernández, Marta;
    • Miguel, Verónica;
    • Márquez‐Expósito, Laura;
    • Nuevo‐Tapioles, Cristina;
    • Herrero, J. Ignacio;
    • Blanco‐Ruiz, Eva;
    • Tituaña, Jessica;
    • Castillo, Carolina;
    • Cannata, Pablo;
    • Monsalve, María;
    • Ruiz‐Ortega, Marta;
    • Ramos, Ricardo;
    • Lamas, Santiago
    Publication type:
    Article

  • Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis.

    Published in:
    2021
    By:
    • Miguel, Verónica;
    • Tituaña, Jessica;
    • Herrero, J. Ignacio;
    • Herrero, Laura;
    • Serra, Dolors;
    • Cuevas-Delgado, Paula;
    • Barbas, Coral;
    • Rodriguez-Puyol, Diego;
    • Marquez-Exposito, Laura;
    • Ruiz-Ortega, Marta;
    • Castillo, Carolina;
    • Xin Sheng;
    • Susztak, Katalin;
    • Ruiz-Canela, Miguel;
    • Salas-Salvado, Jordi;
    • Martinez-Gonzalez, Miguel A.;
    • Ortega, Sagrario;
    • Ramos-Ruiz, Ricardo;
    • Lamas, Santiago;
    • Cuevas, Paula
    Publication type:
    journal article

  • CCN2 Activates RIPK3, NLRP3 Inflammasome, and NRF2/Oxidative Pathways Linked to Kidney Inflammation.

    Published in:
    Antioxidants, 2023, v. 12, n. 8, p. 1541, doi. 10.3390/antiox12081541
    By:
    • Rayego-Mateos, Sandra;
    • Marquez-Exposito, Laura;
    • Basantes, Pamela;
    • Tejedor-Santamaria, Lucia;
    • Sanz, Ana B.;
    • Nguyen, Tri Q.;
    • Goldschmeding, Roel;
    • Ortiz, Alberto;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Oxidative Stress and Cellular Senescence Are Involved in the Aging Kidney.

    Published in:
    Antioxidants, 2022, v. 11, n. 2, p. 301, doi. 10.3390/antiox11020301
    By:
    • Marquez-Exposito, Laura;
    • Tejedor-Santamaria, Lucia;
    • Valentijn, Floris A.;
    • Tejera-Muñoz, Antonio;
    • Rayego-Mateos, Sandra;
    • Marchant, Vanessa;
    • Rodrigues-Diez, Raul R.;
    • Rubio-Soto, Irene;
    • Knoppert, Sebastiaan N.;
    • Ortiz, Alberto;
    • Ramos, Adrian M.;
    • Goldschmeding, Roel;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • CCN2 Aggravates the Immediate Oxidative Stress–DNA Damage Response following Renal Ischemia–Reperfusion Injury.

    Published in:
    Antioxidants, 2021, v. 10, n. 12, p. 2020, doi. 10.3390/antiox10122020
    By:
    • Valentijn, Floris A.;
    • Knoppert, Sebastiaan N.;
    • Pissas, Georgios;
    • Rodrigues-Diez, Raúl R.;
    • Marquez-Exposito, Laura;
    • Broekhuizen, Roel;
    • Mokry, Michal;
    • Kester, Lennart A.;
    • Falke, Lucas L.;
    • Goldschmeding, Roel;
    • Ruiz-Ortega, Marta;
    • Eleftheriadis, Theodoros;
    • Nguyen, Tri Q.
    Publication type:
    Article

  • Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis.

    Published in:
    Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01195
    By:
    • Marquez-Exposito, Laura;
    • Lavoz, Carolina;
    • Rodrigues-Diez, Raul R.;
    • Rayego-Mateos, Sandra;
    • Orejudo, Macarena;
    • Cantero-Navarro, Elena;
    • Ortiz, Alberto;
    • Egido, Jesús;
    • Selgas, Rafael;
    • Mezzano, Sergio;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Statins: Could an old friend help in the fight against COVID‐19?

    Published in:
    British Journal of Pharmacology, 2020, v. 177, n. 21, p. 4873, doi. 10.1111/bph.15166
    By:
    • Rodrigues‐Diez, Raul R.;
    • Tejera‐Muñoz, Antonio;
    • Marquez‐Exposito, Laura;
    • Rayego‐Mateos, Sandra;
    • Santos Sanchez, Laura;
    • Marchant, Vanessa;
    • Tejedor Santamaria, Lucía;
    • Ramos, Adrian M.;
    • Ortiz, Alberto;
    • Egido, Jesus;
    • Ruiz‐Ortega, Marta
    Publication type:
    Article

  • Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis.

    Published in:
    Clinical Science, 2021, v. 135, n. 16, p. 1999, doi. 10.1042/CS20201016
    By:
    • Rayego-Mateos, Sandra;
    • Campillo, Sofia;
    • Rodrigues-Diez, Raúl R.;
    • Tejera-Muñoz, Antonio;
    • Marquez-Exposito, Laura;
    • Goldschmeding, Roel;
    • Rodríguez-Puyol, Diego;
    • Calleros, Laura;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Gremlin activates the Notch pathway linked to renal inflammation.

    Published in:
    Clinical Science, 2018, v. 132, n. 11, p. 1097, doi. 10.1042/CS20171553
    By:
    • Lavoz, Carolina;
    • Poveda, Jonay;
    • Marquez-Exposito, Laura;
    • Rayego-Mateos, Sandra;
    • Rodrigues-Diez, Raul R.;
    • Ortiz, Alberto;
    • Egido, Jesús;
    • Mezzano, Sergio;
    • Ruiz-Ortega, Marta
    Publication type:
    Article

  • Vitamin D, Cellular Senescence and Chronic Kidney Diseases: What Is Missing in the Equation?

    Published in:
    Nutrients, 2023, v. 15, n. 6, p. 1349, doi. 10.3390/nu15061349
    By:
    • Martinelli, Romina P.;
    • Rayego-Mateos, Sandra;
    • Alique, Matilde;
    • Márquez-Expósito, Laura;
    • Tejedor-Santamaria, Lucia;
    • Ortiz, Alberto;
    • González-Parra, Emilio;
    • Ruiz-Ortega, Marta
    Publication type:
    Article