Found: 14

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  • GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice.

    Published in:
    International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2532, doi. 10.3390/ijms22052532
    By:
    • van der Lienden, Martijn J. C.;
    • Aten, Jan;
    • Marques, André R. A.;
    • Waas, Ingeborg S. E.;
    • Larsen, Per W. B.;
    • Claessen, Nike;
    • van der Wel, Nicole N.;
    • Ottenhoff, Roelof;
    • van Eijk, Marco;
    • Aerts, Johannes M. F. G.;
    • Zimran, Ari;
    • Revel-Vilk, Shoshana
    Publication type:
    Article

  • Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain.

    Published in:
    Frontiers in Neuroscience, 2018, p. N.PAG, doi. 10.3389/fnins.2018.00440
    By:
    • van Rooden, Eva J.;
    • van Esbroeck, Annelot C. M.;
    • Baggelaar, Marc P.;
    • Deng, Hui;
    • Florea, Bogdan I.;
    • Marques, André R. A.;
    • Ottenhoff, Roelof;
    • Boot, Rolf G.;
    • Overkleeft, Herman S.;
    • Aerts, Johannes M. F. G.;
    • van der Stelt, Mario
    Publication type:
    Article

  • Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining β-Exoglucosidases In Situ and In Vivo.

    Published in:
    Angewandte Chemie, 2012, v. 124, n. 50, p. 12697, doi. 10.1002/ange.201207771
    By:
    • Kallemeijn, Wouter W.;
    • Li, Kah-Yee;
    • Witte, Martin D.;
    • Marques, André R. A.;
    • Aten, Jan;
    • Scheij, Saskia;
    • Jiang, Jianbing;
    • Willems, Lianne I.;
    • Voorn-Brouwer, Tineke M.;
    • van Roomen, Cindy P. A. A.;
    • Ottenhoff, Roelof;
    • Boot, Rolf G.;
    • van den Elst, Hans;
    • Walvoort, Marthe T. C.;
    • Florea, Bogdan I.;
    • Codée, Jeroen D. C.;
    • van der Marel, Gijsbert A.;
    • Aerts, Johannes M. F. G.;
    • Overkleeft, Herman S.
    Publication type:
    Article

  • Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.

    Published in:
    PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0135889
    By:
    • Marques, André R. A.;
    • Aten, Jan;
    • Ottenhoff, Roelof;
    • van Roomen, Cindy P. A. A.;
    • Herrera Moro, Daniela;
    • Claessen, Nike;
    • Vinueza Veloz, María Fernanda;
    • Zhou, Kuikui;
    • Lin, Zhanmin;
    • Mirzaian, Mina;
    • Boot, Rolf G.;
    • De Zeeuw, Chris I.;
    • Overkleeft, Herman S.;
    • Yildiz, Yildiz;
    • Aerts, Johannes M. F. G.
    Publication type:
    Article

  • A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease.

    Published in:
    ChemBioChem, 2017, v. 18, n. 4, p. 402, doi. 10.1002/cbic.201600561
    By:
    • Marques, André R. A.;
    • Willems, Lianne I.;
    • Herrera Moro, Daniela;
    • Florea, Bogdan I.;
    • Scheij, Saskia;
    • Ottenhoff, Roelof;
    • van Roomen, Cindy P. A. A.;
    • Verhoek, Marri;
    • Nelson, Jessica K.;
    • Kallemeijn, Wouter W.;
    • Biela‐Banas, Anna;
    • Martin, Olivier R.;
    • Cachón‐González, M. Begoña;
    • Kim, Nee Na;
    • Cox, Timothy M.;
    • Boot, Rolf G.;
    • Overkleeft, Herman S.;
    • Aerts, Johannes M. F. G.
    Publication type:
    Article

  • Lentiviral Gene Therapy Using Cellular Promoters Cures Type 1 Gaucher Disease in Mice.

    Published in:
    Molecular Therapy, 2015, v. 23, n. 5, p. 835, doi. 10.1038/mt.2015.16
    By:
    • Dahl, Maria;
    • Doyle, Alexander;
    • Olsson, Karin;
    • Månsson, Jan-Eric;
    • Marques, André R A;
    • Mirzaian, Mina;
    • Aerts, Johannes M;
    • Ehinger, Mats;
    • Rothe, Michael;
    • Modlich, Ute;
    • Schambach, Axel;
    • Karlsson, Stefan
    Publication type:
    Article

  • Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease.

    Published in:
    PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147208
    By:
    • Marques, André R. A.;
    • Gabriel, Tanit L.;
    • Aten, Jan;
    • van Roomen, Cindy P. A. A.;
    • Ottenhoff, Roelof;
    • Claessen, Nike;
    • Alfonso, Pilar;
    • Irún, Pilar;
    • Giraldo, Pilar;
    • Aerts, Johannes M. F. G.;
    • van Eijk, Marco
    Publication type:
    Article

  • Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysosome Dysfunction in Murine Fibroblasts.

    Published in:
    Cells (2073-4409), 2023, v. 12, n. 24, p. 2826, doi. 10.3390/cells12242826
    By:
    • Lopes, Elizeth;
    • Machado-Oliveira, Gisela;
    • Simões, Catarina Guerreiro;
    • Ferreira, Inês S.;
    • Ramos, Cristiano;
    • Ramalho, José;
    • Soares, Maria I. L.;
    • Melo, Teresa M. V. D. Pinho e;
    • Puertollano, Rosa;
    • Marques, André R. A.;
    • Vieira, Otília V.
    Publication type:
    Article

  • Delay of EGF-Stimulated EGFR Degradation in Myotonic Dystrophy Type 1 (DM1).

    Published in:
    Cells (2073-4409), 2022, v. 11, n. 19, p. 3018, doi. 10.3390/cells11193018
    By:
    • Alegre-Cortés, Eva;
    • Giménez-Bejarano, Alberto;
    • Uribe-Carretero, Elisabet;
    • Paredes-Barquero, Marta;
    • Marques, André R. A.;
    • Lopes-da-Silva, Mafalda;
    • Vieira, Otília V.;
    • Canales-Cortés, Saray;
    • Camello, Pedro J.;
    • Martínez-Chacón, Guadalupe;
    • Aiastui, Ana;
    • Fernández-Torrón, Roberto;
    • López de Munain, Adolfo;
    • Gomez-Suaga, Patricia;
    • Niso-Santano, Mireia;
    • González-Polo, Rosa A.;
    • Fuentes, José M.;
    • Yakhine-Diop, Sokhna M. S.
    Publication type:
    Article

  • Cell Senescence, Multiple Organelle Dysfunction and Atherosclerosis.

    Published in:
    Cells (2073-4409), 2020, v. 9, n. 10, p. 2146, doi. 10.3390/cells9102146
    By:
    • Machado-Oliveira, Gisela;
    • Ramos, Cristiano;
    • Marques, André R. A.;
    • Vieira, Otília V.
    Publication type:
    Article

  • Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases.

    Published in:
    FEBS Letters, 2016, v. 590, n. 6, p. 716, doi. 10.1002/1873-3468.12104
    By:
    • Ferraz, Maria J.;
    • Marques, André R. A.;
    • Appelman, Monique D.;
    • Verhoek, Marri;
    • Strijland, Anneke;
    • Mirzaian, Mina;
    • Scheij, Saskia;
    • Ouairy, Cécile M.;
    • Lahav, Daniel;
    • Wisse, Patrick;
    • Overkleeft, Herman S.;
    • Boot, Rolf G.;
    • Aerts, Johannes M.
    Publication type:
    Article

  • Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages.

    Published in:
    Traffic, 2023, v. 24, n. 7, p. 284, doi. 10.1111/tra.12888
    By:
    • Domingues, Neuza;
    • Marques, André R. A.;
    • Calado, Rita Diogo Almeida;
    • Ferreira, Inês S.;
    • Ramos, Cristiano;
    • Ramalho, José;
    • Soares, Maria I. L.;
    • Pereira, Telmo;
    • Oliveira, Luís;
    • Vicente, José R.;
    • Wong, Louise H.;
    • Simões, Inês C. M.;
    • Pinho e Melo, Teresa M. V. D.;
    • Peden, Andrew;
    • Almeida, Cláudia Guimas;
    • Futter, Clare E.;
    • Puertollano, Rosa;
    • Vaz, Winchil L. C.;
    • Vieira, Otília V.
    Publication type:
    Article

  • Current methods to analyze lysosome morphology, positioning, motility and function.

    Published in:
    Traffic, 2022, v. 23, n. 5, p. 238, doi. 10.1111/tra.12839
    By:
    • Barral, Duarte C.;
    • Staiano, Leopoldo;
    • Guimas Almeida, Cláudia;
    • Cutler, Dan F.;
    • Eden, Emily R.;
    • Futter, Clare E.;
    • Galione, Antony;
    • Marques, André R. A.;
    • Medina, Diego Luis;
    • Napolitano, Gennaro;
    • Settembre, Carmine;
    • Vieira, Otília V.;
    • Aerts, Johannes M. F. G.;
    • Atakpa‐Adaji, Peace;
    • Bruno, Gemma;
    • Capuozzo, Antonella;
    • De Leonibus, Elvira;
    • Di Malta, Chiara;
    • Escrevente, Cristina;
    • Esposito, Alessandra
    Publication type:
    Article

  • Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining β-Exoglucosidases In Situ and In Vivo.

    Published in:
    Angewandte Chemie International Edition, 2012, v. 51, n. 50, p. 12529, doi. 10.1002/anie.201207771
    By:
    • Kallemeijn, Wouter W.;
    • Li, Kah-Yee;
    • Witte, Martin D.;
    • Marques, André R. A.;
    • Aten, Jan;
    • Scheij, Saskia;
    • Jiang, Jianbing;
    • Willems, Lianne I.;
    • Voorn-Brouwer, Tineke M.;
    • van Roomen, Cindy P. A. A.;
    • Ottenhoff, Roelof;
    • Boot, Rolf G.;
    • van den Elst, Hans;
    • Walvoort, Marthe T. C.;
    • Florea, Bogdan I.;
    • Codée, Jeroen D. C.;
    • van der Marel, Gijsbert A.;
    • Aerts, Johannes M. F. G.;
    • Overkleeft, Herman S.
    Publication type:
    Article