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Eftozanermin alfa (ABBV-621) monotherapy in patients with previously treated solid tumors: findings of a phase 1, first-in-human study.
- Published in:
- Investigational New Drugs, 2022, v. 40, n. 4, p. 762, doi. 10.1007/s10637-022-01247-1
- By:
- Publication type:
- Article
Phase I study of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehyde-thiosemicarbazone (3-AP) in combination with high dose cytarabine in patients with advanced myeloid leukemia.
- Published in:
- Investigational New Drugs, 2008, v. 26, n. 3, p. 233, doi. 10.1007/s10637-008-9115-6
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- Publication type:
- Article
Phase I trial of orally administered CEP-701, a novel neurotrophin receptor-linked tyrosine kinase inhibitor.
- Published in:
- Investigational New Drugs, 2005, v. 23, n. 1, p. 31, doi. 10.1023/B:DRUG.0000047103.64335.b0
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- Publication type:
- Article
Validation of a Large Custom-Designed Pharmacogenomics Panel on an Array Genotyping Platform.
- Published in:
- Journal of Applied Laboratory Medicine, 2021, v. 6, n. 6, p. 1505, doi. 10.1093/jalm/jfab056
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- Publication type:
- Article
LETTERS AND CORRECTIONS.
- Published in:
- Annals of Internal Medicine, 1985, v. 103, n. 2, p. 302
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- Publication type:
- Article
The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
- Published in:
- PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0202272
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- Publication type:
- Article
Drug-metabolizing enzymes: Evidence for clinical utility of pharmacogenomic tests
- Published in:
- 2005
- By:
- Publication type:
- Editorial
A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2004, v. 76, n. 5, p. 490, doi. 10.1016/j.clpt.2004.07.016
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- Publication type:
- Article
'Irinogenetics' and UGT1A: from Genotypes to Haplotypes<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 6, p. 495, doi. 10.1016/j.clpt.2004.01.011
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- Publication type:
- Article
A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 6, p. 566, doi. 10.1016/S0009-9236(03)00053-5
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- Publication type:
- Article
Population pharmacokinetic model for irinotecan and two of its metabolites, SN-38 and SN-38 glucuronide.
- Published in:
- Clinical Pharmacology & Therapeutics, 2002, v. 72, n. 6, p. 638, doi. 10.1067/mcp.2002.129502
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- Publication type:
- Article
Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 5, p. 576, doi. 10.1016/S0009-9236(99)70078-0
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- Publication type:
- Article
Etoposide combined with interferon alfa-2b: Novel exploitation of established etoposide pharmacokinetics and pharmacodynamics<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 3, p. 349, doi. 10.1016/S0009-9236(96)80013-0
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- Publication type:
- Article
A population model for the leukopenic effect of etoposide<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1995, v. 57, n. 3, p. 325, doi. 10.1016/0009-9236(95)90158-2
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- Publication type:
- Article
Bootstrap validation of pharmacodynamic models defined via stepwise linear regression.
- Published in:
- Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 2, p. 217, doi. 10.1038/clpt.1994.126
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- Publication type:
- Article
Modulation of vinblastine resistance with cyclosporine: A phase I study.
- Published in:
- Clinical Pharmacology & Therapeutics, 1993, v. 54, n. 4, p. 421, doi. 10.1038/clpt.1993.169
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- Publication type:
- Article
A genome-wide integrative study of microRNAs in human liver.
- Published in:
- BMC Genomics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2164-14-395
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- Publication type:
- Article
Cancer pharmacogenomics: strategies and challenges.
- Published in:
- Nature Reviews Genetics, 2013, v. 14, n. 1, p. 23, doi. 10.1038/nrg3352
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- Publication type:
- Article
Pharmacogenomics: will the promise be fulfilled?
- Published in:
- 2011
- By:
- Publication type:
- research
Genetic variation determines VEGF-A plasma levels in cancer patients.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34506-4
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- Publication type:
- Article
A survey of the population genetic variation in the human kinome.
- Published in:
- Journal of Human Genetics, 2009, v. 54, n. 8, p. 488, doi. 10.1038/jhg.2009.72
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- Publication type:
- Article
Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 20, p. 5558, doi. 10.1093/hmg/ddu268
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- Publication type:
- Article
Global gene expression as a function of germline genetic variation.
- Published in:
- Human Molecular Genetics, 2005, v. 14, n. 12, p. 1621, doi. 10.1093/hmg/ddi170
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- Publication type:
- Article
Optimizing the doses of cancer drugs after usual dose finding.
- Published in:
- Clinical Trials, 2024, v. 21, n. 3, p. 340, doi. 10.1177/17407745231213882
- By:
- Publication type:
- Article
Rapid response to 2′-deoxycoformycin in advanced hairy cell leukemia after failure of interferons alpha and gamma.
- Published in:
- American Journal of Hematology, 1988, v. 27, n. 1, p. 60, doi. 10.1002/ajh.2830270114
- By:
- Publication type:
- Article
Re: CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women With Endocrine-Responsive Breast Cancer: The Breast International Group 1-98 Trial.
- Published in:
- 2012
- By:
- Publication type:
- Letter to the Editor
Re: CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women With Endocrine-Responsive Breast Cancer: The Breast International Group 1-98 Trial.
- Published in:
- 2012
- By:
- Publication type:
- Letter
Oncology Micro-Cap Stocks: Caveat Emptor!
- Published in:
- JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 20, p. 1488, doi. 10.1093/jnci/djr375
- By:
- Publication type:
- Article
Opportunities and challenges in the development of experimental drug combinations for cancer.
- Published in:
- 2011
- By:
- Publication type:
- journal article
Opportunities and Challenges in the Development of Experimental Drug Combinations for Cancer.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 16, p. 1222, doi. 10.1093/jnci/djr246
- By:
- Publication type:
- Article
Randomized Phase II Trials: A Long-term Investment With Promising Returns.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 14, p. 1093, doi. 10.1093/jnci/djr218
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- Publication type:
- Article
Cancer Pharmacogenomics and Pharmacoepidemiology: Setting a Research Agenda to Accelerate Translation.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2010, v. 102, n. 22, p. 1698, doi. 10.1093/jnci/djq390
- By:
- Publication type:
- Article
Response.
- Published in:
- 2008
- By:
- Publication type:
- Letter
Design of Phase II Cancer Trials Using a Continuous Endpoint of Change in Tumor Size: Application to a Study of Sorafenib and Erlotinib in Non-Small-Cell Lung Cancer.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2007, v. 99, n. 19, p. 1455, doi. 10.1093/jnci/djm158
- By:
- Publication type:
- Article
Inside Information: Financial Conflicts of Interest for Research Subjects in Early Phase Clinical Trials.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2004, v. 96, n. 9, p. 656, doi. 10.1093/jnci/djh121
- By:
- Publication type:
- Article
Pharmacogenomics: road to anticancer therapeutics nirvana?
- Published in:
- Oncogene, 2003, v. 22, n. 42, p. 6621, doi. 10.1038/sj.onc.1206958
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- Publication type:
- Article
Evaluation of neuropathy in patients on suramin treatment.
- Published in:
- 1997
- By:
- Publication type:
- journal article
Flow cytometry in hairy cell leukemia before and during interferon alfa-2b therapy.
- Published in:
- 1987
- By:
- Publication type:
- journal article
Interventional pharmacoeconomics for immune checkpoint inhibitors through alternative dosing strategies.
- Published in:
- British Journal of Cancer, 2023, v. 129, n. 9, p. 1389, doi. 10.1038/s41416-023-02367-y
- By:
- Publication type:
- Article
Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Correction: Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.
- Published in:
- 2022
- By:
- Publication type:
- corrected article
Paradoxical relationship between acetylator phenotype and amonafide toxicity.
- Published in:
- Clinical Pharmacology & Therapeutics, 1991, v. 50, n. 5, p. 573, doi. 10.1038/clpt.1991.183
- By:
- Publication type:
- Article
Pharmacokinetics and pharmacodynamics of long-term continuous-infusion doxorubicin.
- Published in:
- Clinical Pharmacology & Therapeutics, 1989, v. 45, n. 4, p. 340, doi. 10.1038/clpt.1989.39
- By:
- Publication type:
- Article
Adaptive control of etoposide administration: Impact of interpatient pharmacodynamic variability.
- Published in:
- Clinical Pharmacology & Therapeutics, 1989, v. 45, n. 3, p. 226, doi. 10.1038/clpt.1989.22
- By:
- Publication type:
- Article
Interpatient and intrapatient variability in vinblastine pharmacokinetics.
- Published in:
- Clinical Pharmacology & Therapeutics, 1987, v. 41, n. 1, p. 61, doi. 10.1038/clpt.1987.9
- By:
- Publication type:
- Article
Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue.
- Published in:
- PLoS Genetics, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pgen.1002078
- By:
- Publication type:
- Article
Pentostatin pharmacokinetics and dosing recommendations in patients with mild renal impairment.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 2, p. 121, doi. 10.1007/s00280-002-0468-9
- By:
- Publication type:
- Article
A phase I study of suramin with once- or twice-monthly dosing in patients with advanced cancer.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 1, p. 1, doi. 10.1007/s00280-002-0458-y
- By:
- Publication type:
- Article
Estimation of the effect of food on the disposition of oral 5-fluorouracil in combination with eniluracil.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice.
- Published in:
- 2002
- By:
- Publication type:
- journal article