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Genetic silencing of striatal CaV1.3 prevents and ameliorates levodopa dyskinesia.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Targeted Gene Delivery to the Enteric Nervous System Using AAV: A Comparison Across Serotypes and Capsid Mutants.
- Published in:
- Molecular Therapy, 2015, v. 23, n. 3, p. 488, doi. 10.1038/mt.2015.7
- By:
- Publication type:
- Article
Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Can STN DBS protect both nigral somata and innervation of the striatum?
- Published in:
- 2017
- By:
- Publication type:
- letter
Nicotine-Mediated Recruitment of GABAergic Neurons to a Dopaminergic Phenotype Attenuates Motor Deficits in an Alpha-Synuclein Parkinson's Model.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 4204, doi. 10.3390/ijms24044204
- By:
- Publication type:
- Article
microRNAs: Emerging Targets Regulating Oxidative Stress in the Models of Parkinson's Disease.
- Published in:
- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00298
- By:
- Publication type:
- Article
Commentary: Evaluation of Models of Parkinson's Disease.
- Published in:
- 2016
- By:
- Publication type:
- Opinion
Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates.
- Published in:
- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00012
- By:
- Publication type:
- Article
Orexin (hypocretin) mediates light‐dependent fluctuation of hippocampal function in a diurnal rodent.
- Published in:
- Hippocampus, 2021, v. 31, n. 10, p. 1104, doi. 10.1002/hipo.23376
- By:
- Publication type:
- Article
Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model.
- Published in:
- Molecular Therapy, 2012, v. 20, n. 3, p. 544, doi. 10.1038/mt.2011.216
- By:
- Publication type:
- Article
α-Synuclein Expression in Rat Substantia Nigra Suppresses Phospholipase D2 Toxicity and Nigral Neurodegeneration.
- Published in:
- Molecular Therapy, 2010, v. 18, n. 10, p. 1758, doi. 10.1038/mt.2010.137
- By:
- Publication type:
- Article
In Vivo RNAi-Mediated α-Synuclein Silencing Induces Nigrostriatal Degeneration.
- Published in:
- Molecular Therapy, 2010, v. 18, n. 8, p. 1450, doi. 10.1038/mt.2010.115
- By:
- Publication type:
- Article
Tight Long-term Dynamic Doxycycline Responsive Nigrostriatal GDNF Using a Single rAAV Vector.
- Published in:
- Molecular Therapy, 2009, v. 17, n. 11, p. 1857, doi. 10.1038/mt.2009.196
- By:
- Publication type:
- Article
Nigrostriatal rAAV-mediated GDNF Overexpression Induces Robust Weight Loss in a Rat Model of Age-related Obesity.
- Published in:
- Molecular Therapy, 2009, v. 17, n. 6, p. 980, doi. 10.1038/mt.2009.45
- By:
- Publication type:
- Article
Striatal Readministration of rAAV Vectors Reveals an Immune Response Against AAV2 Capsids That Can Be Circumvented.
- Published in:
- Molecular Therapy, 2009, v. 17, n. 3, p. 524, doi. 10.1038/mt.2008.284
- By:
- Publication type:
- Article
AAV9: a potential blood-brain barrier buster.
- Published in:
- Molecular Therapy, 2009, v. 17, n. 3, p. 403, doi. 10.1038/mt.2009.15
- By:
- Publication type:
- Article
Time Course of Transgene Expression After Intrastriatal Pseudotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 Transduction in the Rat.
- Published in:
- Molecular Therapy, 2007, v. 15, n. 8, p. 1504, doi. 10.1038/sj.mt.6300227
- By:
- Publication type:
- Article
895. Separate rAAV1 Vectors Co-Infect Striatal Neurons Efficiently.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S345, doi. 10.1016/j.ymthe.2006.08.984
- By:
- Publication type:
- Article
903. Re-Administration of Recombinant AAV2 and AAV5 in the Brain.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S348, doi. 10.1016/j.ymthe.2006.08.992
- By:
- Publication type:
- Article
1032. rAAV Mediated Knock-Down of Tyrosine Hydroxylase in the Substantia Nigra Using a pol II Transcribed siRNA.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S396, doi. 10.1016/j.ymthe.2006.08.1127
- By:
- Publication type:
- Article
Recombinant Adeno-associated Viral Vectors as Therapeutic Agents to Treat Neurological Disorders.
- Published in:
- Molecular Therapy, 2006, v. 13, n. 3, p. 463, doi. 10.1016/j.ymthe.2005.11.009
- By:
- Publication type:
- Article
59. rAAV-Mediated Nigral Parkin Over-Expression Is Neuroprotective in the 6-OHDA Rat Model of Parkinson's Disease
- Published in:
- 2005
- By:
- Publication type:
- Abstract
C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer’s disease.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04120-z
- By:
- Publication type:
- Article
A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates.
- Published in:
- PLoS ONE, 2023, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0284480
- By:
- Publication type:
- Article
Therapeutic potential of oxytocin receptor signaling in vascular dementia: Human neuropathology/vascular.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045493
- By:
- Publication type:
- Article
IFNγ drives neuroinflammation, demyelination, and neurodegeneration in a mouse model of multiple system atrophy.
- Published in:
- Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-023-01710-x
- By:
- Publication type:
- Article
Epigenetic inactivation of the autophagy–lysosomal system in appendix in Parkinson's disease.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25474-x
- By:
- Publication type:
- Article
Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081426
- By:
- Publication type:
- Article
Phosphodiesterase 9A Inhibition Facilitates Corticostriatal Transmission in Wild-Type and Transgenic Rats That Model Huntington's Disease.
- Published in:
- Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00466
- By:
- Publication type:
- Article
Striatal Nurrl Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease.
- Published in:
- Journal of Neuroscience, 2020, v. 40, n. 18, p. 3675, doi. 10.1523/jneurosci.2936-19.2020
- By:
- Publication type:
- Article
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.
- Published in:
- Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 422, doi. 10.1172/JCI130513
- By:
- Publication type:
- Article
Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0653-7
- By:
- Publication type:
- Article
A comparison of AAV-vector production methods for gene therapy and preclinical assessment.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-78521-w
- By:
- Publication type:
- Article
The Future of GDNF in Parkinson's Disease.
- Published in:
- Frontiers in Aging Neuroscience, 2020, v. 12, p. N.PAG, doi. 10.3389/fnagi.2020.593572
- By:
- Publication type:
- Article
The contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's disease.
- Published in:
- Journal of Neurochemistry, 2016, v. 137, n. 3, p. 331, doi. 10.1111/jnc.13570
- By:
- Publication type:
- Article
Challenges in Passive Immunization Strategies to Treat Parkinson Disease.
- Published in:
- 2018
- By:
- Publication type:
- Opinion
High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133957
- By:
- Publication type:
- Article
The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-Hydroxydopamine Reveals Significant Upregulation of Regeneration-Associated Genes.
- Published in:
- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0127768
- By:
- Publication type:
- Article
A Method for Combining RNAscope In Situ Hybridization with Immunohistochemistry in Thick Free-Floating Brain Sections and Primary Neuronal Cultures.
- Published in:
- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120120
- By:
- Publication type:
- Article
Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity.
- Published in:
- Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00036
- By:
- Publication type:
- Article
α‐Synuclein stimulation of monoamine oxidase‐B and legumain protease mediates the pathology of Parkinson's disease.
- Published in:
- EMBO Journal, 2018, v. 37, n. 12, p. 1, doi. 10.15252/embj.201798878
- By:
- Publication type:
- Article