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Pathogenesis of hepatitis B virus infection and potential for new therapies.
Published in:
British Journal of Hospital Medicine (17508460), 2012, v. 73, n. 10, p. 581, doi. 10.12968/hmed.2012.73.10.581
By:
- Peppa, Dimitra;
- Maini, Mala K.
Publication type:
Article
Can T Cells Abort SARS-CoV-2 and Other Viral Infections?
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4371, doi. 10.3390/ijms24054371
By:
- Swadling, Leo;
- Maini, Mala K.
Publication type:
Article
Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection.
Published in:
2008
By:
- Lopes, A. Ross;
- Kellam, Paul;
- Das, Abhishek;
- Dunn, Claire;
- Kwan, Antonia;
- Turner, Joanna;
- Peppa, Dimitra;
- Gilson, Richard J.;
- Gehring, Adam;
- Bertoletti, Antonio;
- Maini, Mala K.
Publication type:
journal article
The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV.
Published in:
Vaccines, 2020, v. 8, n. 2, p. 184, doi. 10.3390/vaccines8020184
By:
- Chinnakannan, Senthil K.;
- Cargill, Tamsin N.;
- Donnison, Timothy A.;
- Ansari, M. Azim;
- Sebastian, Sarah;
- Lee, Lian Ni;
- Hutchings, Claire;
- Klenerman, Paul;
- Maini, Mala K.;
- Evans, Tom;
- Barnes, Eleanor
Publication type:
Article
Immune escape pathways from the HBV core18-27 CD8 T cell response are driven by individual HLA class I alleles.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.1045498
By:
- Walker, Andreas;
- Schwarz, Tatjana;
- Brinkmann-Paulukat, Janine;
- Wisskirchen, Karin;
- Menne, Christopher;
- Alizei, Elahe Salimi;
- Kefalakes, Helenie;
- Theissen, Martin;
- Hoffmann, Daniel;
- zur Wiesch, Julian Schulze;
- Maini, Mala K.;
- Cornberg, Markus;
- Kraft, Anke R. M.;
- Keitel, Verena;
- Bock, Hans H.;
- Horn, Peter A.;
- Thimme, Robert;
- Wedemeyer, Heiner;
- Heinemann, Falko M.;
- Luedde, Tom
Publication type:
Article
Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29012-1
By:
- Zakeri, Nekisa;
- Hall, Andrew;
- Swadling, Leo;
- Pallett, Laura J.;
- Schmidt, Nathalie M.;
- Diniz, Mariana O.;
- Kucykowicz, Stephanie;
- Amin, Oliver E.;
- Gander, Amir;
- Pinzani, Massimo;
- Davidson, Brian R.;
- Quaglia, Alberto;
- Maini, Mala K.
Publication type:
Article
Liver-resident memory T cells: life in lockdown.
Published in:
Seminars in Immunopathology, 2022, v. 44, n. 6, p. 813, doi. 10.1007/s00281-022-00932-w
By:
- Pallett, Laura J.;
- Maini, Mala K.
Publication type:
Article
Hepatitis B assessment without hepatitis B virus DNA quantification: a prospective cohort study in Uganda.
Published in:
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2019, v. 113, n. 1, p. 11, doi. 10.1093/trstmh/try117
By:
- Laing, Nicolas;
- Tufton, Henry;
- Ochola, Emmanuel;
- P'Kingston, Ojok Godfrey;
- Maini, Mala K;
- Easom, Nicholas
Publication type:
Article
Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.
Published in:
Nature Medicine, 2015, v. 21, n. 6, p. 591, doi. 10.1038/nm.3856
By:
- Pallett, Laura J;
- Gill, Upkar S;
- Quaglia, Alberto;
- Sinclair, Linda V;
- Jover-Cobos, Maria;
- Schurich, Anna;
- Singh, Kasha P;
- Thomas, Niclas;
- Das, Abhishek;
- Chen, Antony;
- Fusai, Giuseppe;
- Bertoletti, Antonio;
- Cantrell, Doreen A;
- Kennedy, Patrick T;
- Davies, Nathan A;
- Haniffa, Muzlifah;
- Maini, Mala K
Publication type:
Article
Effect of HIV Infection and Antiretroviral Therapy on Hepatitis B Virus (HBV)--Specific T Cell Responses in Patients Who Have Resolved HBV Infection.
Published in:
Journal of Infectious Diseases, 2005, v. 191, n. 7, p. 1169, doi. 10.1086/428502
By:
- Lascar, R. Monica;
- Lopes, A. Ross;
- Gilson, Richard J.;
- Dunn, Claire;
- Johnstone, Ruth;
- Copas, Andrew;
- Reignat, Stephanie;
- Webster, George;
- Bertoletti, Antonio;
- Maini, Mala K.
Publication type:
Article
Reconstitution of Hepatitis B Virus (HBV)--Specific T Cell Responses with Treatment of Human Immunodeficiency Virus/ HBV Coinfection.
Published in:
Journal of Infectious Diseases, 2003, v. 188, n. 12, p. 1815, doi. 10.1086/379896
By:
- Lascar, R. Monica;
- Gilson, Richard J.;
- Lopes, A. Ross;
- Bertoletti, Antonio;
- Maini, Mala K.
Publication type:
Article
Innate and Adaptive Immune Responses in Hepatitis B Virus Infection.
Published in:
Digestive Diseases, 2010, v. 28, n. 1, p. 126, doi. 10.1159/000282075
By:
- Das, Abhishek;
- Maini, Mala K.
Publication type:
Article
Cholesterol-modifying drugs in COVID-19.
Published in:
Oxford Open Immunology, 2020, v. 1, n. 1, p. 1, doi. 10.1093/oxfimm/iqaa001
By:
- Schmidt, Nathalie M.;
- Wing, Peter A. C.;
- McKeating, Jane A.;
- Maini, Mala K.
Publication type:
Article
CXCR6 marks a novel subset of T-betloEomeshi natural killer cells residing in human liver.
Published in:
Scientific Reports, 2016, p. 26157, doi. 10.1038/srep26157
By:
- Stegmann, Kerstin A.;
- Robertson, Francis;
- Hansi, Navjyot;
- Gill, Upkar;
- Pallant, Celeste;
- Christophides, Theodoros;
- Pallett, Laura J.;
- Peppa, Dimitra;
- Dunn, Claire;
- Fusai, Giuseppe;
- Male, Victoria;
- Davidson, Brian R.;
- Kennedy, Patrick;
- Maini, Mala K.
Publication type:
Article
IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01009
By:
- Easom, Nicholas J. W.;
- Stegmann, Kerstin A.;
- Swadling, Leo;
- Pallett, Laura J.;
- Burton, Alice R.;
- Odera, Dennis;
- Schmidt, Nathalie;
- Huang, Wei-Chen;
- Fusai, Giuseppe;
- Davidson, Brian;
- Maini, Mala K.
Publication type:
Article
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42433-w
By:
- Mitsi, Elena;
- Diniz, Mariana O.;
- Reiné, Jesús;
- Collins, Andrea M.;
- Robinson, Ryan E.;
- Hyder-Wright, Angela;
- Farrar, Madlen;
- Liatsikos, Konstantinos;
- Hamilton, Josh;
- Onyema, Onyia;
- Urban, Britta C.;
- Solórzano, Carla;
- Belij-Rammerstorfer, Sandra;
- Sheehan, Emma;
- Lambe, Teresa;
- Draper, Simon J.;
- Weiskopf, Daniela;
- Sette, Alessandro;
- Maini, Mala K.;
- Ferreira, Daniela M.
Publication type:
Article
Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40460-1
By:
- Altmann, Daniel M.;
- Reynolds, Catherine J.;
- Joy, George;
- Otter, Ashley D.;
- Gibbons, Joseph M.;
- Pade, Corinna;
- Swadling, Leo;
- Maini, Mala K.;
- Brooks, Tim;
- Semper, Amanda;
- McKnight, Áine;
- Noursadeghi, Mahdad;
- Manisty, Charlotte;
- Treibel, Thomas A.;
- Moon, James C.;
- Boyton, Rosemary J.
Publication type:
Article
Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection.
Published in:
PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047648
By:
- Nebbia, Gaia;
- Peppa, Dimitra;
- Schurich, Anna;
- Khanna, Pooja;
- Singh, Harsimran D.;
- Yang Cheng;
- Rosenberg, William;
- Dusheiko, Geoffrey;
- Gilson, Richard;
- Aleong, Joanne Chin;
- Kennedy, Patrick;
- Maini, Mala K.
Publication type:
Article
Licensing Virus-Specific T Cells to Secrete the Neutrophil Attracting Chemokine CXCL-8 during Hepatitis B Virus Infection.
Published in:
PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023330
By:
- Gehring, Adam J.;
- Koh, Sarene;
- Chia, Adeline;
- Paramasivam, Komathi;
- Valerie Suk Peng Chew;
- Zi Zong Ho;
- Kang Hoe Lee;
- Maini, Mala K.;
- Madhavan, Krishnakumar;
- Lim, Seng Gee;
- Bertoletti, Antonio
Publication type:
Article
Living in the liver: hepatic infections.
Published in:
2012
By:
- Protzer U;
- Maini MK;
- Knolle PA;
- Protzer, Ulrike;
- Maini, Mala K;
- Knolle, Percy A
Publication type:
journal article
Living in the liver: hepatic infections.
Published in:
Nature Reviews Immunology, 2012, v. 12, n. 3, p. 201, doi. 10.1038/nri3169
By:
- Protzer, Ulrike;
- Maini, Mala K.;
- Knolle, Percy A.
Publication type:
Article
Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID‐19.
Published in:
Immunological Reviews, 2021, v. 299, n. 1, p. 108, doi. 10.1111/imr.12953
By:
- Burton, Alice R.;
- Maini, Mala K.
Publication type:
Article
Circulating and intrahepatic antiviral B cells are defective in hepatitis B.
Published in:
2018
By:
- Burton, Alice R.;
- Pallett, Laura J.;
- McCoy, Laura E.;
- Suveizdyte, Kornelija;
- Amin, Oliver E.;
- Swadling, Leo;
- Alberts, Elena;
- Davidson, Brian R.;
- Kennedy, Patrick T. F.;
- Gill, Upkar S.;
- Mauri, Claudia;
- Blair, Paul A.;
- Pelletier, Nadege;
- Maini, Mala K.;
- Kennedy, Patrick Tf
Publication type:
journal article
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
Published in:
PLoS Pathogens, 2016, v. 12, n. 8, p. 1, doi. 10.1371/journal.ppat.1005788
By:
- Gill, Upkar S.;
- Peppa, Dimitra;
- Micco, Lorenzo;
- Singh, Harsimran D.;
- Carey, Ivana;
- Foster, Graham R.;
- Maini, Mala K.;
- Kennedy, Patrick T. F.
Publication type:
Article
The Third Signal Cytokine IL-12 Rescues the Anti-Viral Function of Exhausted HBV-Specific CD8 T Cells.
Published in:
PLoS Pathogens, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.ppat.1003208
By:
- Schurich, Anna;
- Pallett, Laura J.;
- Lubowiecki, Marcin;
- Singh, Harsimran D.;
- Gill, Upkar S.;
- Kennedy, Patrick T.;
- Nastouli, Eleni;
- Tanwar, Sudeep;
- Rosenberg, William;
- Maini, Mala K.
Publication type:
Article
Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection.
Published in:
PLoS Pathogens, 2010, v. 6, n. 12, p. 1, doi. 10.1371/journal.ppat.1001227
By:
- Peppa, Dimitra;
- Micco, Lorenzo;
- Javaid, Alia;
- Kennedy, Patrick T. F.;
- Schurich, Anna;
- Dunn, Claire;
- Pallant, Celeste;
- Ellis, Gidon;
- Khanna, Pooja;
- Dusheiko, Geoffrey;
- Gilson, Richard J.;
- Maini, Mala K.
Publication type:
Article
Chronic Hepatitis B Finite Treatment: Similar and Different Concerns With New Drug Classes.
Published in:
Clinical Infectious Diseases, 2024, v. 78, n. 4, p. 983, doi. 10.1093/cid/ciad506
By:
- Peters, Marion G;
- Yuen, Man-Fung;
- Terrault, Norah;
- Fry, John;
- Lampertico, Pietro;
- Gane, Ed;
- Hwang, Carey;
- Stamm, Luisa M;
- Leus, Mitchell;
- Maini, Mala K;
- Mendez, Patricia;
- Lonjon-Domanec, Isabelle;
- Berg, Thomas;
- Wang, Su;
- Mishra, Poonam;
- Donaldson, Eric;
- Buchholz, Stephanie;
- Miller, Veronica;
- Lenz, Oliver
Publication type:
Article
NK cells limit therapeutic vaccine–induced CD8+T cell immunity in a PD-L1–dependent manner.
Published in:
Science Translational Medicine, 2022, v. 14, n. 640, p. 1, doi. 10.1126/scitranslmed.abi4670
By:
- Diniz, Mariana O.;
- Schurich, Anna;
- Chinnakannan, Senthil K.;
- Duriez, Marion;
- Stegmann, Kerstin A.;
- Davies, Jessica;
- Kucykowicz, Stephanie;
- Suveizdyte, Kornelija;
- Amin, Oliver E.;
- Alcock, Frances;
- Cargill, Tamsin;
- Barnes, Eleanor;
- Maini, Mala K.
Publication type:
Article
ULBP1 Is Elevated in Human Hepatocellular Carcinoma and Predicts Outcome.
Published in:
Frontiers in Oncology, 2020, v. 11, p. 1, doi. 10.3389/fonc.2020.00971
By:
- Easom, Nicholas J. W.;
- Marks, Michael;
- Jobe, Dawda;
- Gillmore, Roopinder;
- Meyer, Tim;
- Maini, Mala K.;
- Njie, Ramou
Publication type:
Article
T cell receptor usage of virus-specific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection.
Published in:
European Journal of Immunology, 2000, v. 30, n. 11, p. 3067, doi. 10.1002/1521-4141(200011)30:11<3067::AID-IMMU3067>3.0.CO;2-L
By:
- Maini, Mala K.;
- Reignat, Stephanie;
- Boni, Carolina;
- Ogg, Graham S.;
- King, Abigail S.;
- Malacarne, Fabio;
- Webster, George J. M.;
- Bertoletti, Antonio
Publication type:
Article
An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity.
Published in:
PLoS Pathogens, 2023, v. 18, n. 5, p. 1, doi. 10.1371/journal.ppat.1011323
By:
- Wing, Peter AC;
- Schmidt, Nathalie M.;
- Peters, Rory;
- Erdmann, Maximilian;
- Brown, Rachel;
- Wang, Hao;
- Swadling, Leo;
- Newman, Joseph;
- Thakur, Nazia;
- Shionoya, Kaho;
- Morgan, Sophie B.;
- Hinks, Timothy SC;
- Watashi, Koichi;
- Bailey, Dalan;
- Hansen, Scott B.;
- Davidson, Andrew D.;
- Maini, Mala K.;
- McKeating, Jane A.
Publication type:
Article

Found: 31

Pathogenesis of hepatitis B virus infection and potential for new therapies.

Can T Cells Abort SARS-CoV-2 and Other Viral Infections?

Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection.

The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV.

Immune escape pathways from the HBV core<sub>18-27</sub> CD8 T cell response are driven by individual HLA class I alleles.

Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma.

Liver-resident memory T cells: life in lockdown.

Hepatitis B assessment without hepatitis B virus DNA quantification: a prospective cohort study in Uganda.

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.

Effect of HIV Infection and Antiretroviral Therapy on Hepatitis B Virus (HBV)--Specific T Cell Responses in Patients Who Have Resolved HBV Infection.

Reconstitution of Hepatitis B Virus (HBV)--Specific T Cell Responses with Treatment of Human Immunodeficiency Virus/ HBV Coinfection.

Innate and Adaptive Immune Responses in Hepatitis B Virus Infection.

Cholesterol-modifying drugs in COVID-19.

CXCR6 marks a novel subset of T-bet<sup>lo</sup>Eomes<sup>hi</sup> natural killer cells residing in human liver.

IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.

Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination.

Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity.

Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection.

Licensing Virus-Specific T Cells to Secrete the Neutrophil Attracting Chemokine CXCL-8 during Hepatitis B Virus Infection.

Living in the liver: hepatic infections.

Living in the liver: hepatic infections.

Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID‐19.

Circulating and intrahepatic antiviral B cells are defective in hepatitis B.

Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.

The Third Signal Cytokine IL-12 Rescues the Anti-Viral Function of Exhausted HBV-Specific CD8 T Cells.

Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection.

Chronic Hepatitis B Finite Treatment: Similar and Different Concerns With New Drug Classes.

NK cells limit therapeutic vaccine–induced CD8<sup>+</sup>T cell immunity in a PD-L1–dependent manner.

ULBP1 Is Elevated in Human Hepatocellular Carcinoma and Predicts Outcome.

T cell receptor usage of virus-specific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection.

An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity.