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COMT val158met polymorphism links to altered fear conditioning and extinction are modulated by PTSD and childhood trauma.
Published in:
2018
By:
- Deslauriers, Jessica;
- Acheson, Dean T.;
- Maihofer, Adam X.;
- Nievergelt, Caroline M.;
- Baker, Dewleen G.;
- Geyer, Mark A.;
- Risbrough, Victoria B.;
- Marine Resiliency Study Team
Publication type:
journal article
Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture.
Published in:
Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-03152-y
By:
- Morey, Rajendra A.;
- Zheng, Yuanchao;
- Bayly, Henry;
- Sun, Delin;
- Garrett, Melanie E.;
- Gasperi, Marianna;
- Maihofer, Adam X.;
- Baird, C. Lexi;
- Grasby, Katrina L.;
- Huggins, Ashley A.;
- Haswell, Courtney C.;
- Thompson, Paul M.;
- Medland, Sarah;
- Gustavson, Daniel E.;
- Panizzon, Matthew S.;
- Kremen, William S.;
- Nievergelt, Caroline M.;
- Ashley-Koch, Allison E.;
- Logue, Mark W.
Publication type:
Article
Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.
Published in:
2018
By:
- Almli, Lynn M.;
- Lori, Adriana;
- Meyers, Jacquelyn L.;
- Shin, Jaemin;
- Fani, Negar;
- Maihofer, Adam X.;
- Nievergelt, Caroline M.;
- Smith, Alicia K.;
- Mercer, Kristina B.;
- Kerley, Kimberly;
- Leveille, Jennifer M.;
- Feng, Hao;
- Abu‐Amara, Duna;
- Flory, Janine D.;
- Yehuda, Rachel;
- Marmar, Charles R.;
- Baker, Dewleen G.;
- Bradley, Bekh;
- Koenen, Karestan C.;
- Conneely, Karen N.
Publication type:
journal article
Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study.
Published in:
2019
By:
- Greenwood, Tiffany A.;
- Lazzeroni, Laura C.;
- Maihofer, Adam X.;
- Swerdlow, Neal R.;
- Calkins, Monica E.;
- Freedman, Robert;
- Green, Michael F.;
- Light, Gregory A.;
- Nievergelt, Caroline M.;
- Nuechterlein, Keith H.;
- Radant, Allen D.;
- Siever, Larry J.;
- Silverman, Jeremy M.;
- Stone, William S.;
- Sugar, Catherine A.;
- Tsuang, Debby W.;
- Tsuang, Ming T.;
- Turetsky, Bruce I.;
- Gur, Ruben C.;
- Gur, Raquel E.
Publication type:
journal article
Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers.
Published in:
2016
By:
- Stein, Murray B.;
- Chia-Yen Chen;
- Ursano, Robert J.;
- Tianxi Cai;
- Gelernter, Joel;
- Heeringa, Steven G.;
- Jain, Sonia;
- Jensen, Kevin P.;
- Maihofer, Adam X.;
- Mitchell, Colter;
- Nievergelt, Caroline M.;
- Nock, Matthew K.;
- Neale, Benjamin M.;
- Polimanti, Renato;
- Ripke, Stephan;
- Xiaoying Sun;
- Thomas, Michael L.;
- Qian Wang;
- Ware, Erin B.;
- Borja, Susan
Publication type:
journal article
Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines.
Published in:
2015
By:
- Minassian, Arpi;
- Maihofer, Adam X.;
- Baker, Dewleen G.;
- Nievergelt, Caroline M.;
- Geyer, Mark A.;
- Risbrough, Victoria B.;
- Marine Resiliency Study Team
Publication type:
journal article
Assessment of Plasma C-Reactive Protein as a Biomarker of Posttraumatic Stress Disorder Risk.
Published in:
JAMA Psychiatry, 2014, v. 71, n. 4, p. 423, doi. 10.1001/jamapsychiatry.2013.4374
By:
- Eraly, Satish A.;
- Nievergelt, Caroline M.;
- Maihofer, Adam X.;
- Barkauskas, Donald A.;
- Biswas, Nilima;
- Agorastos, Agorastos;
- O'Connor, Daniel T.;
- Baker, Dewleen G.
Publication type:
Article
Genome‐wide analyses of psychological resilience in U.S. Army soldiers.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2019, v. 180, n. 5, p. 310, doi. 10.1002/ajmg.b.32730
By:
- Stein, Murray B.;
- Choi, Karmel W.;
- Jain, Sonia;
- Campbell‐Sills, Laura;
- Chen, Chia‐Yen;
- Gelernter, Joel;
- He, Feng;
- Heeringa, Steven G.;
- Maihofer, Adam X.;
- Nievergelt, Caroline;
- Nock, Matthew K.;
- Ripke, Stephan;
- Sun, Xiaoying;
- Kessler, Ronald C.;
- Smoller, Jordan W.;
- Ursano, Robert J.
Publication type:
Article
Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2017, v. 174, n. 6, p. 619, doi. 10.1002/ajmg.b.32568
By:
- Ratanatharathorn, Andrew;
- Boks, Marco P.;
- Maihofer, Adam X.;
- Aiello, Allison E.;
- Amstadter, Ananda B.;
- Ashley‐Koch, Allison E.;
- Baker, Dewleen G.;
- Beckham, Jean C.;
- Bromet, Evelyn;
- Dennis, Michelle;
- Garrett, Melanie E.;
- Geuze, Elbert;
- Guffanti, Guia;
- Hauser, Michael A.;
- Kilaru, Varun;
- Kimbrel, Nathan A.;
- Koenen, Karestan C.;
- Kuan, Pei‐Fen;
- Logue, Mark W.;
- Luft, Benjamin J.
Publication type:
Article
Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system.
Published in:
BMC Medical Genetics, 2016, v. 17, p. 1, doi. 10.1186/s12881-016-0283-5
By:
- Biswas, Nilima;
- Maihofer, Adam X.;
- Anam Mir, Saiful;
- Rao, Fangwen;
- Zhang, Kuixing;
- Khandrika, Srikrishna;
- Mahata, Manjula;
- Friese, Ryan S.;
- Makena Hightower, C.;
- Mahata, Sushil K.;
- Baker, Dewleen G.;
- Nievergelt, Caroline M.;
- Vaingankar, Sucheta M.;
- O'Connor, Daniel T.
Publication type:
Article
Effects of genetically predicted posttraumatic stress disorder on autoimmune phenotypes.
Published in:
Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-02869-0
By:
- Maihofer, Adam X.;
- Ratanatharathorn, Andrew;
- Hemmings, Sian M. J.;
- Costenbader, Karen H.;
- Michopoulos, Vasiliki;
- Polimanti, Renato;
- Rothbaum, Alex O.;
- Seedat, Soraya;
- Mikita, Elizabeth A.;
- Smith, Alicia K.;
- Salem, Rany M.;
- Shaffer, Richard A.;
- Wu, Tianying;
- Sebat, Jonathan;
- Ressler, Kerry J.;
- Stein, Murray B.;
- Koenen, Karestan C.;
- Wolf, Erika J.;
- Sumner, Jennifer A.;
- Nievergelt, Caroline M.
Publication type:
Article
Polygenic risk for mental disorders as predictors of posttraumatic stress disorder after mild traumatic brain injury.
Published in:
Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02313-9
By:
- Stein, Murray B.;
- Jain, Sonia;
- Parodi, Livia;
- Choi, Karmel W.;
- Maihofer, Adam X.;
- Nelson, Lindsay D.;
- Mukherjee, Pratik;
- Sun, Xiaoying;
- He, Feng;
- Okonkwo, David O.;
- Giacino, Joseph T.;
- Korley, Frederick K.;
- Vassar, Mary J.;
- Robertson, Claudia S.;
- McCrea, Michael A.;
- Temkin, Nancy;
- Markowitz, Amy J.;
- Diaz-Arrastia, Ramon;
- Rosand, Jonathan;
- Manley, Geoffrey T.
Publication type:
Article
Genetic architecture distinguishes tinnitus from hearing loss.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44842-x
By:
- Clifford, Royce E.;
- Maihofer, Adam X.;
- Chatzinakos, Chris;
- Coleman, Jonathan R. I.;
- Daskalakis, Nikolaos P.;
- Gasperi, Marianna;
- Hogan, Kelleigh;
- Mikita, Elizabeth A.;
- Stein, Murray B.;
- Tcheandjieu, Catherine;
- Telese, Francesca;
- Zuo, Yanning;
- Ryan, Allen F.;
- Nievergelt, Caroline M.
Publication type:
Article
Sex differences in the polygenic architecture of hearing problems in adults.
Published in:
Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01186-3
By:
- De Angelis, Flavio;
- Zeleznik, Oana A.;
- Wendt, Frank R.;
- Pathak, Gita A.;
- Tylee, Daniel S.;
- De Lillo, Antonella;
- Koller, Dora;
- Cabrera-Mendoza, Brenda;
- Clifford, Royce E.;
- Maihofer, Adam X.;
- Nievergelt, Caroline M.;
- Curhan, Gary C.;
- Curhan, Sharon G.;
- Polimanti, Renato
Publication type:
Article
Sex differences in the polygenic architecture of hearing problems in adults.
Published in:
Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01186-3
By:
- De Angelis, Flavio;
- Zeleznik, Oana A.;
- Wendt, Frank R.;
- Pathak, Gita A.;
- Tylee, Daniel S.;
- De Lillo, Antonella;
- Koller, Dora;
- Cabrera-Mendoza, Brenda;
- Clifford, Royce E.;
- Maihofer, Adam X.;
- Nievergelt, Caroline M.;
- Curhan, Gary C.;
- Curhan, Sharon G.;
- Polimanti, Renato
Publication type:
Article
Trauma and posttraumatic stress disorder modulate polygenic predictors of hippocampal and amygdala volume.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01707-x
By:
- Zheng, Yuanchao;
- Garrett, Melanie E.;
- Sun, Delin;
- Clarke-Rubright, Emily K.;
- Haswell, Courtney C.;
- Maihofer, Adam X.;
- Elman, Jeremy A.;
- Franz, Carol E.;
- Lyons, Michael J.;
- Kremen, William S.;
- Peverill, Matthew;
- Sambrook, Kelly;
- McLaughlin, Katie A.;
- Davenport, Nicholas D.;
- Disner, Seth;
- Sponheim, Scott R.;
- Andrew, Elpiniki;
- Korgaonkar, Mayuresh;
- Bryant, Richard;
- Varkevisser, Tim
Publication type:
Article
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12576-w
By:
- Nievergelt, Caroline M.;
- Maihofer, Adam X.;
- Klengel, Torsten;
- Atkinson, Elizabeth G.;
- Chen, Chia-Yen;
- Choi, Karmel W.;
- Coleman, Jonathan R. I.;
- Dalvie, Shareefa;
- Duncan, Laramie E.;
- Gelernter, Joel;
- Levey, Daniel F.;
- Logue, Mark W.;
- Polimanti, Renato;
- Provost, Allison C.;
- Ratanatharathorn, Andrew;
- Stein, Murray B.;
- Torres, Katy;
- Aiello, Allison E.;
- Almli, Lynn M.;
- Amstadter, Ananda B.
Publication type:
Article
Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis.
Published in:
Frontiers in Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnins.2021.678503
By:
- Sumner, Jennifer A.;
- Maihofer, Adam X.;
- Michopoulos, Vasiliki;
- Rothbaum, Alex O.;
- Almli, Lynn M.;
- Andreassen, Ole A.;
- Ashley-Koch, Allison E.;
- Baker, Dewleen G.;
- Beckham, Jean C.;
- Bradley, Bekh;
- Breen, Gerome;
- Coleman, Jonathan R. I.;
- Dale, Anders M.;
- Dennis, Michelle F.;
- Feeny, Norah C.;
- Franz, Carol E.;
- Garrett, Melanie E.;
- Gillespie, Charles F.;
- Guffanti, Guia;
- Hauser, Michael A.
Publication type:
Article
Genomic influences on self-reported childhood maltreatment.
Published in:
Translational Psychiatry, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41398-020-0706-0
By:
- Dalvie, Shareefa;
- Maihofer, Adam X.;
- Coleman, Jonathan R. I.;
- Bradley, Bekh;
- Breen, Gerome;
- Brick, Leslie A.;
- Chen, Chia-Yen;
- Choi, Karmel W.;
- Duncan, Laramie E.;
- Guffanti, Guia;
- Haas, Magali;
- Harnal, Supriya;
- Liberzon, Israel;
- Nugent, Nicole R.;
- Provost, Allison C.;
- Ressler, Kerry J.;
- Torres, Katy;
- Amstadter, Ananda B.;
- Bryn Austin, S.;
- Baker, Dewleen G.
Publication type:
Article
Inference of human continental origin and admixture proportions using a highly discriminative ancestry informative 41-SNP panel.
Published in:
Investigative Genetics, 2013, v. 4, n. 1, p. 1, doi. 10.1186/2041-2223-4-13
By:
- Nievergelt, Caroline M.;
- Maihofer, Adam X.;
- Shekhtman, Tatyana;
- Libiger, Ondrej;
- Xudong Wang;
- Kidd, Kenneth K.;
- Kidd, Judith R.
Publication type:
Article
Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study.
Published in:
JAMA Network Open, 2019, p. e193447, doi. 10.1001/jamanetworkopen.2019.3447
By:
- Polimanti, Renato;
- Ratanatharathorn, Andrew;
- Maihofer, Adam X.;
- Choi, Karmel W.;
- Stein, Murray B.;
- Morey, Rajendra A.;
- Logue, Mark W.;
- Nievergelt, Caroline M.;
- Stein, Dan J.;
- Koenen, Karestan C.;
- Gelernter, Joel
Publication type:
Article
Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling.
Published in:
Clinical Kidney Journal, 2016, v. 9, n. 3, p. 444, doi. 10.1093/ckj/sfw010
By:
- Bhatnagar, Vibha;
- Richard, Erin L.;
- Wei Wu;
- Nievergelt, Caroline M.;
- Lipkowitz, Michael S.;
- Jeff, Janina;
- Maihofer, Adam X.;
- Nigam, Sanjay K.
Publication type:
Article
Novel Risk Loci in Tinnitus and Causal Inference With Neuropsychiatric Disorders Among Adults of European Ancestry.
Published in:
2020
By:
- Clifford, Royce E.;
- Maihofer, Adam X.;
- Stein, Murray B.;
- Ryan, Allen F.;
- Nievergelt, Caroline M.
Publication type:
journal article
Identification of novel loci affecting circulating chromogranins and related peptides.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 1, p. 233, doi. 10.1093/hmg/ddw380
By:
- Benyamin, Beben;
- Maihofer, Adam X.;
- Schork, Andrew J.;
- Hamilton, Bruce A.;
- Fangwen Rao;
- Schmid-Schönbein, Geert W.;
- Kuixing Zhang;
- Mahata, Manjula;
- Stridsberg, Mats;
- Schork, Nicholas J.;
- Biswas, Nilima;
- Hook, Vivian Y.;
- Zhiyun Wei;
- Montgomery, Grant W.;
- Martin, Nicholas G.;
- Nievergelt, Caroline M.;
- Whitfield, John B.;
- O'Connor, Daniel T.
Publication type:
Article
The catecholamine biosynthetic enzyme dopamine β-hydroxylase (DBH): first genome-wide search positions trait-determining variants acting additively in the proximal promoter.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 23, p. 6375, doi. 10.1093/hmg/ddu332
By:
- Mustapic, Maja;
- Maihofer, Adam X.;
- Mahata, Manjula;
- Chen, Yuqing;
- Baker, Dewleen G.;
- O'Connor, Daniel T.;
- Nievergelt, Caroline M.
Publication type:
Article
Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder.
Published in:
Clinical Epigenetics, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13148-019-0798-7
By:
- Snijders, Clara;
- Maihofer, Adam X.;
- Ratanatharathorn, Andrew;
- Baker, Dewleen G.;
- Boks, Marco P.;
- Geuze, Elbert;
- Jain, Sonia;
- Kessler, Ronald C.;
- Pishva, Ehsan;
- Risbrough, Victoria B.;
- Stein, Murray B.;
- Ursano, Robert J.;
- Vermetten, Eric;
- Vinkers, Christiaan H.;
- Smith, Alicia K.;
- Uddin, Monica;
- Rutten, Bart P. F.;
- Nievergelt, Caroline M.
Publication type:
Article
A - 7 Genome-Wide Association Study of Traumatic Brain Injury in U.S. Military Veterans.
Published in:
Archives of Clinical Neuropsychology, 2023, v. 38, n. 7, p. 1153, doi. 10.1093/arclin/acad067.013
By:
- Merritt, Victoria C;
- Maihofer, Adam X;
- Gasperi, Marianna;
- Ketema, Elizabeth;
- Chanfreau-Coffinier, Catherine;
- Stein, Murray B;
- Panizzon, Matthew S;
- Hauger, Richard L;
- Logue, Mark W;
- Delano-Wood, Lisa;
- Nievergelt, Caroline M
Publication type:
Article
Association of polygenic risk scores, traumatic life events and coping strategies with war-related PTSD diagnosis and symptom severity in the South Eastern Europe (SEE)-PTSD cohort.
Published in:
Journal of Neural Transmission, 2022, v. 129, n. 5/6, p. 661, doi. 10.1007/s00702-021-02446-5
By:
- Weber, Heike;
- Maihofer, Adam X.;
- Jaksic, Nenad;
- Bojic, Elma Feric;
- Kucukalic, Sabina;
- Dzananovic, Emina Sabic;
- Uka, Aferdita Goci;
- Hoxha, Blerina;
- Haxhibeqiri, Valdete;
- Haxhibeqiri, Shpend;
- Kravic, Nermina;
- Umihanic, Mirnesa Muminovic;
- Franc, Ana Cima;
- Babic, Romana;
- Pavlovic, Marko;
- Mehmedbasic, Alma Bravo;
- Aukst-Margetic, Branka;
- Kucukalic, Abdulah;
- Marjanovic, Damir;
- Babic, Dragan
Publication type:
Article
Associations between Serum Levels of Cholesterol and Survival to Age 90 in Postmenopausal Women.
Published in:
Journal of the American Geriatrics Society, 2020, v. 68, n. 2, p. 288, doi. 10.1111/jgs.16306
By:
- Maihofer, Adam X.;
- Shadyab, Aladdin H.;
- Wild, Robert A.;
- LaCroix, Andrea Z.
Publication type:
Article
Critical evaluation of copy number variant calling methods using DNA methylation.
Published in:
Genetic Epidemiology, 2020, v. 44, n. 2, p. 148, doi. 10.1002/gepi.22269
By:
- Kilaru, Varun;
- Knight, Anna K.;
- Katrinli, Seyma;
- Cobb, Dawayland;
- Lori, Adriana;
- Gillespie, Charles F.;
- Maihofer, Adam X.;
- Nievergelt, Caroline M.;
- Dunlop, Anne L.;
- Conneely, Karen N.;
- Smith, Alicia K.
Publication type:
Article
Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19615-x
By:
- Smith, Alicia K.;
- Ratanatharathorn, Andrew;
- Maihofer, Adam X.;
- Naviaux, Robert K.;
- Aiello, Allison E.;
- Amstadter, Ananda B.;
- Ashley-Koch, Allison E.;
- Baker, Dewleen G.;
- Beckham, Jean C.;
- Boks, Marco P.;
- Bromet, Evelyn;
- Dennis, Michelle;
- Galea, Sandro;
- Garrett, Melanie E.;
- Geuze, Elbert;
- Guffanti, Guia;
- Hauser, Michael A.;
- Katrinli, Seyma;
- Kilaru, Varun;
- Kessler, Ronald C.
Publication type:
Article
A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder.
Published in:
Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-017-0491-4
By:
- Polimanti, Renato;
- Amstadter, Ananda B.;
- Stein, Murray B.;
- Almli, Lynn M.;
- Baker, Dewleen G.;
- Bierut, Laura J.;
- Bradley, Bekh;
- Farrer, Lindsay A.;
- Johnson, Eric O.;
- King, Anthony;
- Kranzler, Henry R.;
- Maihofer, Adam X.;
- Rice, John P.;
- Roberts, Andrea L.;
- Saccone, Nancy L.;
- Hongyu Zhao;
- Liberzon, Israel;
- Ressler, Kerry J.;
- Nievergelt, Caroline M.;
- Koenen, Karestan C.
Publication type:
Article
Clinical predictors of non‐response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study.
Published in:
Bipolar Disorders, 2021, v. 23, n. 8, p. 821, doi. 10.1111/bdi.13078
By:
- Lin, Yian;
- Maihofer, Adam X.;
- Stapp, Emma;
- Ritchey, Megan;
- Alliey‐Rodriguez, Ney;
- Anand, Amit;
- Balaraman, Yokesh;
- Berrettini, Wade H.;
- Bertram, Holli;
- Bhattacharjee, Abesh;
- Calkin, Cynthia V.;
- Conroy, Carla;
- Coryell, William;
- D'Arcangelo, Nicole;
- DeModena, Anna;
- Biernacka, Joanna M.;
- Fisher, Carrie;
- Frazier, Nicole;
- Frye, Mark;
- Gao, Keming
Publication type:
Article

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