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The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population.
- Published in:
- Diabetologia, 2023, v. 66, n. 5, p. 847, doi. 10.1007/s00125-023-05870-2
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- Publication type:
- Article
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression.
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- Diabetologia, 2023, v. 66, n. 4, p. 674, doi. 10.1007/s00125-022-05856-6
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- Article
Analysis of overlapping genetic association in type 1 and type 2 diabetes.
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- Diabetologia, 2021, v. 64, n. 6, p. 1342, doi. 10.1007/s00125-021-05428-0
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- Article
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium.
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- Diabetologia, 2019, v. 62, n. 9, p. 1601, doi. 10.1007/s00125-019-4906-1
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- Article
Genome-wide association study of type 2 diabetes in Africa.
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- Diabetologia, 2019, v. 62, n. 7, p. 1204, doi. 10.1007/s00125-019-4880-7
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- Publication type:
- Article
Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.
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- Diabetologia, 2016, v. 59, n. 7, p. 1446, doi. 10.1007/s00125-016-3920-9
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- Publication type:
- Article
Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity.
- Published in:
- Nutrients, 2018, v. 10, n. 11, p. 1791, doi. 10.3390/nu10111791
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- Publication type:
- Article
Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.
- Published in:
- PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0189886
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- Publication type:
- Article
Genetic variation in the CYP2B6 Gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study.
- Published in:
- Environmental Health: A Global Access Science Source, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-069X-13-34
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- Publication type:
- Article
Genetic variation in the CYP2B6 gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study.
- Published in:
- 2014
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- Publication type:
- journal article
Common variants of SLAMF1 and ITLN1 on 1q21 are associated with type 2 diabetes in Indian population.
- Published in:
- Journal of Human Genetics, 2012, v. 57, n. 3, p. 184, doi. 10.1038/jhg.2011.150
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- Publication type:
- Article
Common variants of FTO and the risk of obesity and type 2 diabetes in Indians.
- Published in:
- Journal of Human Genetics, 2011, v. 56, n. 10, p. 720, doi. 10.1038/jhg.2011.87
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- Publication type:
- Article
Association of variants in genes involved in pancreatic β-cell development and function with type 2 diabetes in North Indians.
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- Journal of Human Genetics, 2011, v. 56, n. 10, p. 695, doi. 10.1038/jhg.2011.83
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- Publication type:
- Article
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
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- Nature Communications, 2017, v. 8, n. 4, p. 14977, doi. 10.1038/ncomms14977
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- Publication type:
- Article
Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data.
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- Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0628-8
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- Publication type:
- Article
1132-P: Genetic Relationships between Birth Weight and Type 2 Diabetes.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-1132-P
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- Publication type:
- Article
Large-Scale Analyses Provide No Evidence for Gene-Gene Interactions Influencing Type 2 Diabetes Risk.
- Published in:
- 2020
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- Publication type:
- journal article
1460-P: Type 2 Diabetes Polygenic Score in Addition to Clinical Factors for Prediction of Diabetes Incidence in an Indigenous American Population.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1460-P
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- Publication type:
- Article
Genetic Predisposition to Type 2 Diabetes and Risk of Subclinical Atherosclerosis and Cardiovascular Diseases Among 160,000 Chinese Adults.
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- 2019
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- Publication type:
- journal article
3-LB: The Type 2 Diabetes-Associated Transcription Factor RREB1 Affects Beta-Cell Function and Development.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-3-LB
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- Publication type:
- Article
309-OR: Deep Learning Model of Pancreatic Islet Epigenome Refines Association Signals at Type 2 Diabetes Susceptibility Loci.
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- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-309-OR
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- Publication type:
- Article
306-OR: Gene-Environment Interactions for Type 2 Diabetes in UK Biobank.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-306-OR
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- Publication type:
- Article
303-OR: ADA Presidents' Select Abstract: Transethnic Association Study of Type 2 Diabetes in More than a Million Individuals.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-303-OR
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- Publication type:
- Article
189-OR: Plasma Proteome Profiling of Prediabetes and Diabetes Progression: An IMI Direct Study.
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- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-189-OR
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- Publication type:
- Article
1845-P: Divergent Effects on T2D of Alleles Associated with Increased Liver Fat Reflect Differential Impact on Hepatic Glucose and Lipid Output: An IMI DIRECT Study.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1845-P
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- Publication type:
- Article
Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension.
- Published in:
- 2019
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- Publication type:
- journal article
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
- Published in:
- 2017
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- Publication type:
- journal article
A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.
- Published in:
- 2017
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- Publication type:
- journal article
A Low-Frequency Inactivating Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
- Published in:
- 2017
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- Publication type:
- journal article
Genome-Wide Association Study for Type 2 Diabetes in Indians Identifies a New Susceptibility Locus at 2q21.
- Published in:
- Diabetes, 2013, v. 62, n. 3, p. 977, doi. 10.2337/db12-0406
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- Publication type:
- Article
Impact of Common Variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the Risk of Type 2 Diabetes in 5,164 Indians.
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- Diabetes, 2010, v. 59, n. 8, p. 2068, doi. 10.2337/db09-1386
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- Article
FTO genotype is associated with phenotypic variability of body mass index.
- Published in:
- Nature, 2012, v. 490, n. 7419, p. 267, doi. 10.1038/nature11401
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- Publication type:
- Article
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
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- Nature Genetics, 2014, v. 46, n. 4, p. 357, doi. 10.1038/ng.2915
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- Publication type:
- Article
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
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- Nature Genetics, 2012, v. 44, n. 9, p. 981, doi. 10.1038/ng.2383
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- Publication type:
- Article
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
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- PLoS Genetics, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.pgen.1005230
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- Publication type:
- Article
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus.
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- PLoS Genetics, 2015, v. 11, n. 1, p. 1, doi. 10.1371/journal.pgen.1004876
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- Publication type:
- Article
Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.
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- 2018
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- Publication type:
- journal article
Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals.
- Published in:
- eLife, 2020, p. 1, doi. 10.7554/eLife.51503
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- Publication type:
- Article
Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci.
- Published in:
- eLife, 2018, p. 1, doi. 10.7554/eLife.31977
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- Publication type:
- Article
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-07867-7
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- Publication type:
- Article
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04611-z
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- Publication type:
- Article
Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children.
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- Journal of Pediatric Endocrinology & Metabolism, 2017, v. 30, n. 5, p. 507, doi. 10.1515/jpem-2016-0435
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- Publication type:
- Article
The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 9, p. e1697, doi. 10.1210/clinem/dgae119
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- Publication type:
- Article
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity.
- Published in:
- 2021
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- Publication type:
- journal article
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.
- Published in:
- European Journal of Epidemiology, 2019, v. 34, n. 3, p. 279, doi. 10.1007/s10654-019-00502-9
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- Publication type:
- Article
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18581-8
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- Publication type:
- Article
Common Variants in CRP and LEPR Influence High Sensitivity C-Reactive Protein Levels in North Indians.
- Published in:
- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024645
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- Publication type:
- Article
High-Sensitivity C-Reactive Protein Levels and Type 2 Diabetes in Urban North Indians.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2009, v. 94, n. 6, p. 2123, doi. 10.1210/jc.2008-2754
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- Publication type:
- Article
Correction: Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.
- Published in:
- 2019
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- Publication type:
- Correction Notice
Causal relationships between obesity and the leading causes of death in women and men.
- Published in:
- PLoS Genetics, 2019, v. 15, n. 10, p. 1, doi. 10.1371/journal.pgen.1008405
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- Publication type:
- Article