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In Memoriam: Darrell R. Abernethy 1949–2017.
- Published in:
- 2018
- By:
- Publication type:
- Obituary
Editorial: Model-informed decision making in the preclinical stages of pharmaceutical research and development.
- Published in:
- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1184914
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- Publication type:
- Article
Population Pharmacokinetic Model of N-acetylmannosamine (ManNAc) and N-acetylneuraminic acid (Neu5Ac) in Subjects with GNE Myopathy.
- Published in:
- Drugs in R&D, 2021, v. 21, n. 2, p. 189, doi. 10.1007/s40268-021-00343-6
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- Publication type:
- Article
Application of Pharmacokinetic and Pharmacodynamic Analysis to the Development of Liposomal Formulations for Oncology.
- Published in:
- Pharmaceutics, 2014, v. 6, n. 1, p. 137, doi. 10.3390/pharmaceutics6010137
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- Publication type:
- Article
Machine Learning Models for the Prediction of Chemotherapy-Induced Peripheral Neuropathy.
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 2, p. 1, doi. 10.1007/s11095-018-2562-7
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- Publication type:
- Article
Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells.
- Published in:
- 2020
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- Publication type:
- journal article
Immunosuppressant adherence in adult outpatient hematopoietic cell transplant recipients.
- Published in:
- Journal of Oncology Pharmacy Practice, 2024, v. 30, n. 2, p. 322, doi. 10.1177/10781552231171607
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- Publication type:
- Article
Factor VIII associated with lipidic nanoparticles retains efficacy in the presence of anti-factor VIII antibodies in hemophilia A mice.
- Published in:
- Biopharmaceutics & Drug Disposition, 2016, v. 37, n. 7, p. 409, doi. 10.1002/bdd.2023
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- Publication type:
- Article
Effects of hypertonic buffer composition on lymph node uptake and bioavailability of rituximab, after subcutaneous administration.
- Published in:
- Biopharmaceutics & Drug Disposition, 2015, v. 36, n. 2, p. 115, doi. 10.1002/bdd.1925
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- Publication type:
- Article
Nonlinear pharmacokinetics of factor VIII and its phosphatidylinositol lipidic complex in hemophilia A mice.
- Published in:
- Biopharmaceutics & Drug Disposition, 2014, v. 35, n. 3, p. 154, doi. 10.1002/bdd.1880
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- Publication type:
- Article
Population-based meta-analysis of furosemide pharmacokinetics.
- Published in:
- Biopharmaceutics & Drug Disposition, 2014, v. 35, n. 2, p. 119, doi. 10.1002/bdd.1874
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- Publication type:
- Article
Population-based meta-analysis of hydrochlorothiazide pharmacokinetics.
- Published in:
- Biopharmaceutics & Drug Disposition, 2013, v. 34, n. 9, p. 527, doi. 10.1002/bdd.1863
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- Publication type:
- Article
Population pharmacokinetics of tolvaptan in healthy subjects and patients with hyponatremia secondary to congestive heart failure or hepatic cirrhosis.
- Published in:
- Biopharmaceutics & Drug Disposition, 2013, v. 34, n. 6, p. 336, doi. 10.1002/bdd.1849
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- Publication type:
- Article
Integrated model for denosumab and ibandronate pharmacodynamics in postmenopausal women.
- Published in:
- Biopharmaceutics & Drug Disposition, 2011, v. 32, n. 8, p. 471, doi. 10.1002/bdd.770
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- Publication type:
- Article
Systems Pharmacology Modeling Identifies a Novel Treatment Strategy for Bortezomib-Induced Neuropathic Pain.
- Published in:
- Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.817236
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- Publication type:
- Article
FOLFIRINOX Pharmacodynamic Interactions in 2D and 3D Pancreatic Cancer Cell Cultures.
- Published in:
- AAPS Journal, 2022, v. 24, n. 6, p. 1, doi. 10.1208/s12248-022-00752-8
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- Publication type:
- Article
Cluster Gauss–Newton and CellNOpt Parameter Estimation in a Small Protein Signaling Network of Vorinostat and Bortezomib Pharmacodynamics.
- Published in:
- AAPS Journal, 2021, v. 23, n. 6, p. 1, doi. 10.1208/s12248-021-00640-7
- By:
- Publication type:
- Article
Network-Based Systems Analysis Explains Sequence-Dependent Synergism of Bortezomib and Vorinostat in Multiple Myeloma.
- Published in:
- AAPS Journal, 2021, v. 23, n. 5, p. 1, doi. 10.1208/s12248-021-00622-9
- By:
- Publication type:
- Article
Race-specific coregulatory and transcriptomic profiles associated with DNA methylation and androgen receptor in prostate cancer.
- Published in:
- Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01323-6
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- Publication type:
- Article
Abciximab Pharmacodynamic Model with Neural Networks used to Integrate Sources of Patient Variability<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 1, p. 60, doi. 10.1016/j.clpt.2003.09.008
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- Publication type:
- Article
Pharmacodynamic modeling of time-dependent transduction systems<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 3, p. 210, doi. 10.1067/mcp.2001.118244
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- Publication type:
- Article
Enantioselective pharmacokinetics of ( R)- and ( S)-ketamine after a 5-day infusion in patients with complex regional pain syndrome.
- Published in:
- Chirality, 2011, v. 23, n. 2, p. 138, doi. 10.1002/chir.20890
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- Publication type:
- Article
The impact of tacrolimus exposure on extrarenal adverse effects in adult renal transplant recipients.
- Published in:
- British Journal of Clinical Pharmacology, 2019, v. 85, n. 3, p. 516, doi. 10.1111/bcp.13811
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- Publication type:
- Article
Population pharmacokinetics of exenatide.
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 3, p. 517, doi. 10.1111/bcp.13135
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- Publication type:
- Article
Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression.
- Published in:
- British Journal of Clinical Pharmacology, 2012, v. 74, n. 2, p. 304, doi. 10.1111/j.1365-2125.2012.04198.x
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- Publication type:
- Article
Pharmacodynamic profiles of ketamine (R)- and (S)- with 5-day inpatient infusion for the treatment of complex regional pain syndrome.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Pharmacodynamic Profiles of Ketamine (R)- and (S)- with 5-Day Inpatient Infusion for the Treatment of Complex Regional Pain Syndrome.
- Published in:
- Pain Physician, 2010, v. 13, n. 4, p. 379
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- Publication type:
- Article
Pharmacometrics and Systems Pharmacology 2030.
- Published in:
- Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 1, p. 76, doi. 10.1002/cpt.1683
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- Publication type:
- Article
Pharmacodynamic Drug–Drug Interactions.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 6, p. 1395, doi. 10.1002/cpt.1434
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- Publication type:
- Article
Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats.
- Published in:
- FASEB Journal, 2006, v. 20, n. 6, p. 631, doi. 10.1096/fj.05-5263com
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- Publication type:
- Article
Rituximab dosing in hematological malignancies: an old question, revisited.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Quantitative structure–property relationships of camptothecins in humans.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Quantitative structure–property relationships of camptothecins in humans.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 2, p. 325, doi. 10.1007/s00280-009-1037-2
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- Publication type:
- Article
Quantitative systems pharmacology modeling of tumor heterogeneity in response to BH3‐mimetics using virtual tumors calibrated with cell viability assays.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 7, p. 1252, doi. 10.1002/psp4.13158
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- Publication type:
- Article
Pharmacodynamic Models of Differential Bortezomib Signaling Across Several Cell Lines of Multiple Myeloma.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 3, p. 146, doi. 10.1002/psp4.12358
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- Publication type:
- Article
Cell Signaling Model Connects Vorinostat Pharmacokinetics and Tumor Growth Response in Multiple Myeloma Xenografts.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2017, v. 6, n. 11, p. 756, doi. 10.1002/psp4.12246
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- Publication type:
- Article
Inter-Antibody Variability in the Clinical Pharmacokinetics of Monoclonal Antibodies Characterized Using Population Physiologically Based Pharmacokinetic Modeling.
- Published in:
- Antibodies (2073-4468), 2024, v. 13, n. 3, p. 54, doi. 10.3390/antib13030054
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- Publication type:
- Article
Systems model identifies baseline cytokine concentrations as potential predictors of rheumatoid arthritis inflammatory response to biologics.
- Published in:
- British Journal of Pharmacology, 2022, v. 179, n. 16, p. 4063, doi. 10.1111/bph.15845
- By:
- Publication type:
- Article
Population Pharmacodynamic Modelling of Aspirin- and Ibuprofen-Induced Inhibition of Platelet Aggregation in Healthy Subjects.
- Published in:
- Clinical Pharmacokinetics, 2008, v. 47, n. 2, p. 129, doi. 10.2165/00003088-200847020-00006
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- Publication type:
- Article
Merging Systems Biology with Pharmacodynamics.
- Published in:
- Science Translational Medicine, 2012, v. 4, n. 126, p. 1, doi. 10.1126/scitranslmed.3003563
- By:
- Publication type:
- Article
A Limited Sampling Schedule to Estimate Mycophenolic Acid Area Under the Concentration-Time Curve in Hematopoietic Cell Transplantation Recipients.
- Published in:
- Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1654, doi. 10.1177/0091270011429567
- By:
- Publication type:
- Article
Population Pharmacokinetic Model for a Novel Oral Hypoglycemic Formed In Vivo: Comparing the Use of Active Metabolite Data Alone Versus Using Data of Upstream and Downstream Metabolites.
- Published in:
- Journal of Clinical Pharmacology, 2012, v. 52, n. 3, p. 404, doi. 10.1177/0091270010396373
- By:
- Publication type:
- Article
Bridging Pharmacology and Pathophysiology via Systems Modeling.
- Published in:
- Journal of Clinical Pharmacology, 2010, v. 50, n. 9, p. 56S, doi. 10.1177/0091270010377505
- By:
- Publication type:
- Article
Quantitative Structure-Property Relationships Modeling to Predict In Vitro and In Vivo Binding of Drugs to the Bile Sequestrant, Colesevelam (Welchol).
- Published in:
- Journal of Clinical Pharmacology, 2009, v. 49, n. 10, p. 1185, doi. 10.1177/0091270009340783
- By:
- Publication type:
- Article
Population Exposure-Response Modeling of Metformin in Patients With Type 2 Diabetes Mellitus.
- Published in:
- Journal of Clinical Pharmacology, 2008, v. 48, n. 6, p. 696, doi. 10.1177/0091270008316884
- By:
- Publication type:
- Article
Dose Equivalency Evaluation of Major Corticosteroids: Pharmacokinetics and Cell Trafficking and Cortisol Dynamics.
- Published in:
- Journal of Clinical Pharmacology, 2003, v. 43, n. 11, p. 1216, doi. 10.1177/0091270003258651
- By:
- Publication type:
- Article
Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Comparison of sequential and joint nonlinear mixed effects modeling of tumor kinetics and survival following Durvalumab treatment in patients with metastatic urothelial carcinoma.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2023, v. 50, n. 4, p. 251, doi. 10.1007/s10928-023-09848-w
- By:
- Publication type:
- Article
Accelerating robust plausible virtual patient cohort generation by substituting ODE simulations with parameter space mapping.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 6, p. 625, doi. 10.1007/s10928-022-09826-8
- By:
- Publication type:
- Article
Population-based meta-analysis of bortezomib exposure–response relationships in multiple myeloma patients.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 1, p. 77, doi. 10.1007/s10928-019-09670-3
- By:
- Publication type:
- Article