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The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 11, p. N.PAG, doi. 10.15252/emmm.201809316
By:
- Neumann, Ulf;
- Ufer, Mike;
- Jacobson, Laura H;
- Rouzade‐Dominguez, Marie‐Laure;
- Huledal, Gunilla;
- Kolly, Carine;
- Lüönd, Rainer M;
- Machauer, Rainer;
- Veenstra, Siem J;
- Hurth, Konstanze;
- Rueeger, Heinrich;
- Tintelnot‐Blomley, Marina;
- Staufenbiel, Matthias;
- Shimshek, Derya R;
- Perrot, Ludovic;
- Frieauff, Wilfried;
- Dubost, Valerie;
- Schiller, Hilmar;
- Vogg, Barbara;
- Beltz, Karen
Publication type:
Article
Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice.
Published in:
Scientific Reports, 2016, p. 21917, doi. 10.1038/srep21917
By:
- Shimshek, Derya R.;
- Jacobson, Laura H.;
- Kolly, Carine;
- Zamurovic, Natasa;
- Balavenkatraman, Kamal Kumar;
- Morawiec, Laurent;
- Kreutzer, Robert;
- Schelle, Juliane;
- Jucker, Mathias;
- Bertschi, Barbara;
- Theil, Diethilde;
- Heier, Annabelle;
- Bigot, Karine;
- Beltz, Karen;
- Machauer, Rainer;
- Brzak, Irena;
- Perrot, Ludovic;
- Neumann, Ulf
Publication type:
Article
Synthesis of Lipidated eNOS Peptides by Combining Enzymatic, Noble Metal- and Acid-Mediated Protecting Group Techniques with Solid Phase Peptide Synthesis and Fragment Condensation in Solution.
Published in:
Chemistry - A European Journal, 2001, v. 7, n. 13, p. 2940, doi. 10.1002/1521-3765(20010702)7:13<2933::AID-CHEM2933>3.0.CO;2-E
By:
- Machauer, Rainer;
- Waldmann, Herbert
Publication type:
Article
The β-secretase (BACE) inhibitor NB-360 in preclinical models: From amyloid-β reduction to downstream disease-relevant effects.
Published in:
2019
By:
- Neumann, Ulf;
- Machauer, Rainer;
- Shimshek, Derya R.
Publication type:
journal article
Synthesis of the N-Terminal N-Myristoylated and S-Palmitoylated Undetrigintapeptide of Endothelial NO-Synthase.
Published in:
Angewandte Chemie International Edition, 2000, v. 39, n. 8, p. 1449, doi. 10.1002/(SICI)1521-3773(20000417)39:8<1449::AID-ANIE1449>3.0.CO;2-A
By:
- Machauer, Rainer;
- Waldmann, Herbert
Publication type:
Article
A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.
Published in:
Molecular Neurodegeneration, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13024-015-0033-8
By:
- Neumann, Ulf;
- Rueeger, Heinrich;
- Machauer, Rainer;
- Veenstra, Siem Jacob;
- Lueoend, Rainer M.;
- Tintelnot-Blomley, Marina;
- Laue, Grit;
- Beltz, Karen;
- Vogg, Barbara;
- Schmid, Peter;
- Frieauff, Wilfried;
- Shimshek, Derya R.;
- Staufenbiel, Matthias;
- Jacobson, Laura H.
Publication type:
Article

Found: 6

The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease.

Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice.

Synthesis of Lipidated eNOS Peptides by Combining Enzymatic, Noble Metal- and Acid-Mediated Protecting Group Techniques with Solid Phase Peptide Synthesis and Fragment Condensation in Solution.

The β-secretase (BACE) inhibitor NB-360 in preclinical models: From amyloid-β reduction to downstream disease-relevant effects.

Synthesis of the N-Terminal N-Myristoylated and S-Palmitoylated Undetrigintapeptide of Endothelial NO-Synthase.

A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.