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Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF.
Published in:
2019
By:
- Mills, Ross;
- Mathur, Abhinav;
- Nicol, Lisa M.;
- Walker, Jeremy J.;
- Przybylski, Alexander A.;
- Mackinnon, Alison C.;
- Howie, Sarah E. M.;
- Wallace, William A. H.;
- Dransfield, Ian;
- Hirani, Nik
Publication type:
journal article
Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation.
Published in:
Frontiers in Pharmacology, 2022, v. 10, p. 1, doi. 10.3389/fphar.2022.949264
By:
- Humphries, Duncan C.;
- Mills, Ross;
- Boz, Cecilia;
- McHugh, Brian J.;
- Hirani, Nikhil;
- Rossi, Adriano G.;
- Pedersen, Anders;
- Schambye, Hans T.;
- Slack, Robert J.;
- Leffler, Hakon;
- Nilsson, Ulf J.;
- Wei Wang;
- Sethi, Tariq;
- Mackinnon, Alison C.
Publication type:
Article
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo.
Published in:
Nature Medicine, 1999, v. 5, n. 6, p. 662, doi. 10.1038/9511
By:
- Sethi, Tariq;
- Rintoul, Robert C.;
- Moore, Sarah M.;
- MacKinnon, Alison C.;
- Salter, Donald;
- Choo, Chin;
- Chilvers, Edwin R.;
- Dransfield, Ian;
- Donnelly, Seamas C.;
- Strieter, Robert;
- Haslett, Christopher
Publication type:
Article
Selective Myeloid Depletion of Galectin-3 Offers Protection Against Acute and Chronic Lung Injury.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.715986
By:
- Humphries, Duncan C.;
- Mills, Ross;
- Dobie, Ross;
- Henderson, Neil C.;
- Sethi, Tariq;
- Mackinnon, Alison C.
Publication type:
Article
Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: A Role for Bone Marrow Derived Macrophages.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086241
By:
- Kallis, Yiannis N.;
- Scotton, Christopher J.;
- MacKinnon, Alison C.;
- Goldin, Robert D.;
- Wright, Nicholas A.;
- Iredale, John P.;
- Chambers, Rachel C.;
- Forbes, Stuart J.
Publication type:
Article
An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE).
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 2, p. 138, doi. 10.1164/rccm.202203-0477OC
By:
- Gaughan, Erin E.;
- Quinn, Tom M.;
- Mills, Andrew;
- Bruce, Annya M.;
- Antonelli, Jean;
- MacKinnon, Alison C.;
- Aslanis, Vassilios;
- Feng Li;
- O'Connor, Richard;
- Boz, Cecilia;
- Mills, Ross;
- Emanuel, Philip;
- Burgess, Matthew;
- Rinaldi, Giulia;
- Valanciute, Asta;
- Mills, Bethany;
- Scholefield, Emma;
- Hardisty, Gareth;
- Findlay, Emily Gwyer;
- Parker, Richard A.
Publication type:
Article
Resistance to anti-PD-1/anti-PDL1: galectin-3 inhibition with GB1211 reverses galectin-3- induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1250559
By:
- Mabbitt, Joseph;
- Holyer, Ian D.;
- Roper, James A.;
- Nilsson, Ulf J.;
- Zetterberg, Fredrik R.;
- Lynda Vuong;
- Mackinnon, Alison C.;
- Pedersen, Anders;
- Slack, Robert J.
Publication type:
Article
Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3.
Published in:
2012
By:
- Mackinnon AC;
- Gibbons MA;
- Farnworth SL;
- Leffler H;
- Nilsson UJ;
- Delaine T;
- Simpson AJ;
- Forbes SJ;
- Hirani N;
- Gauldie J;
- Sethi T;
- Mackinnon, Alison C;
- Gibbons, Michael A;
- Farnworth, Sarah L;
- Leffler, Hakon;
- Nilsson, Ulf J;
- Delaine, Tamara;
- Simpson, A John;
- Forbes, Stuart J;
- Hirani, Nik
Publication type:
journal article
Regulation of Transforming Growth Factor-β1--driven Lung Fibrosis by Galectin-3.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 5, p. 537, doi. 10.1164/rccm.201106-0965OC
By:
- MacKinnon, Alison C.;
- Gibbons, Michael A.;
- Farnworth, Sarah L.;
- Leffler, Hakon;
- Nilsson, UIf J.;
- Delaine, Tamara;
- Simpson, A. John;
- Forbes, Stuart J.;
- Hirani, Nik;
- Gauldie, Jack;
- Sethi, Tariq
Publication type:
Article
Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis.
Published in:
2011
By:
- Gibbons MA;
- MacKinnon AC;
- Ramachandran P;
- Dhaliwal K;
- Duffin R;
- Phythian-Adams AT;
- van Rooijen N;
- Haslett C;
- Howie SE;
- Simpson AJ;
- Gibbons, Michael A;
- MacKinnon, Alison C;
- Ramachandran, Prakash;
- Dhaliwal, Kevin;
- Duffin, Rodger;
- Phythian-Adams, Alexander T;
- van Rooijen, Nico;
- Haslett, Christopher;
- Howie, Sarah E;
- Simpson, A John
Publication type:
journal article
Ly6C<sup>hi</sup> Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2011, v. 184, n. 5, p. 569, doi. 10.1164/rccm.201010-1719OC
By:
- Gibbons, Michael A.;
- MacKinnon, Alison C.;
- Ramachandran, Prakash;
- Dhaliwal, Kevin;
- Duffin, Rodger;
- Phythian-Adams, Alexander T.;
- van Rooijen, Nico;
- Haslett, Christopher;
- Howie, Sarah E.;
- Simpson, A. John;
- Hirani, Nikhil;
- Gauldie, Jack;
- Iredale, John P.;
- Sethi, Tariq;
- Forbes, Stuart J.
Publication type:
Article
Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor: a single- and multiple-dose first-in-human study in healthy participants.
Published in:
Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 3, p. 267, doi. 10.1007/s00280-023-04513-y
By:
- Aslanis, Vassilios;
- Slack, Robert J.;
- MacKinnon, Alison C.;
- McClinton, Catherine;
- Tantawi, Susan;
- Gravelle, Lise;
- Nilsson, Ulf J.;
- Leffler, Hakon;
- Brooks, Ashley;
- Khindri, Sanjeev K.;
- Marshall, Richard P.;
- Pedersen, Anders;
- Schambye, Hans;
- Zetterberg, Fredrik
Publication type:
Article
The molecular and cellular biology of lung cancer: identifying novel therapeutic strategies.
Published in:
British Medical Bulletin, 2010, v. 95, n. 1, p. 47, doi. 10.1093/bmb/ldq023
By:
- MacKinnon, Alison C.;
- Kopatz, Jens;
- Sethi, Tariq
Publication type:
Article
Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice.
Published in:
Glycobiology, 2013, v. 23, n. 6, p. 654, doi. 10.1093/glycob/cwt006
By:
- MacKinnon, Alison C;
- Liu, Xiaojun;
- Hadoke, Patrick WF;
- Miller, Mark R;
- Newby, David E;
- Sethi, Tariq
Publication type:
Article

Found: 14