Found: 49
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Recapitulating human cancer in a mouse.
- Published in:
- Nature Biotechnology, 2013, v. 31, n. 5, p. 392, doi. 10.1038/nbt.2575
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- Publication type:
- Article
Chimeric mouse tumor models reveal differences in pathway activation between ERBB family– and KRAS-dependent lung adenocarcinomas.
- Published in:
- Nature Biotechnology, 2010, v. 28, n. 1, p. 71, doi. 10.1038/nbt.1595
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- Publication type:
- Article
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
- Published in:
- Nature Medicine, 2012, v. 18, n. 12, p. 1857, doi. 10.1038/nm1212-1857a
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- Publication type:
- Article
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
- Published in:
- Nature Medicine, 2012, v. 18, n. 10, p. 1503, doi. 10.1038/nm.2941
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- Publication type:
- Article
Cancer genomics: from discovery science to personalized medicine.
- Published in:
- Nature Medicine, 2011, v. 17, n. 3, p. 297, doi. 10.1038/nm.2323
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- Publication type:
- Article
Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion.
- Published in:
- British Journal of Haematology, 2016, v. 173, n. 1, p. 161, doi. 10.1111/bjh.13574
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- Publication type:
- Article
Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice.
- Published in:
- Nature Genetics, 2005, v. 37, n. 7, p. 750, doi. 10.1038/ng1587
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- Publication type:
- Article
Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation.
- Published in:
- Nature Genetics, 2000, v. 26, n. 1, p. 85, doi. 10.1038/79232
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- Publication type:
- Article
Somatic Mutations of PIK3R1 Promote Gliomagenesis.
- Published in:
- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049466
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- Publication type:
- Article
Integrative Genome Comparison of Primary and Metastatic Melanomas.
- Published in:
- PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010770
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- Publication type:
- Article
Targeting EGFR Induced Oxidative Stress by PARP1 Inhibition in Glioblastoma Therapy.
- Published in:
- PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010767
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- Publication type:
- Article
BRAF Activation Initiates but Does Not Maintain Invasive Prostate Adenocarcinoma.
- Published in:
- PLoS ONE, 2008, v. 3, n. 12, p. 1, doi. 10.1371/journal.pone.0003949
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- Publication type:
- Article
Emerging patterns of somatic mutations in cancer.
- Published in:
- Nature Reviews Genetics, 2013, v. 14, n. 10, p. 703, doi. 10.1038/nrg3539
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- Publication type:
- Article
p16(Ink4a) in melanocyte senescence and differentiation.
- Published in:
- 2002
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- Publication type:
- journal article
P16[sup Ink4a] in Melanocyte Senescence and Differentiation.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2002, v. 94, n. 6, p. 446, doi. 10.1093/jnci/94.6.446
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- Publication type:
- Article
Both products of the mouse Ink4a/Arf locus suppress melanoma formation in vivo.
- Published in:
- Oncogene, 2003, v. 22, n. 32, p. 5055, doi. 10.1038/sj.onc.1206809
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- Publication type:
- Article
The INK4a/ARF locus and melanoma.
- Published in:
- Oncogene, 2003, v. 22, n. 20, p. 3092, doi. 10.1038/sj.onc.1206461
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- Publication type:
- Article
Guest Editor.
- Published in:
- Oncogene, 2003, v. 22, n. 20, p. 3015, doi. 10.1038/sj.onc.1206441
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- Publication type:
- Article
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
- Published in:
- Nature, 2010, v. 468, n. 7324, p. 701, doi. 10.1038/nature09595
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- Publication type:
- Article
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.
- Published in:
- Nature, 2009, v. 459, n. 7250, p. 1085, doi. 10.1038/nature08109
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- Publication type:
- Article
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
- Published in:
- Nature, 2008, v. 455, n. 7216, p. 1129, doi. 10.1038/nature07443
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- Publication type:
- Article
Translating insights from the cancer genome into clinical practice.
- Published in:
- Nature, 2008, v. 452, n. 7187, p. 553, doi. 10.1038/nature06914
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- Publication type:
- Article
Modeling malignant melanoma in mice: pathogenesis and maintenance.
- Published in:
- Oncogene, 1999, v. 18, n. 38, p. 5304, doi. 10.1038/sj.onc.1203106
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- Publication type:
- Article
Differential effects of the widely expressed dMax splice variant of Max on E-box vs initiator element-mediated regulation by c-Myc.
- Published in:
- Oncogene, 1999, v. 18, n. 15, p. 2489, doi. 10.1038/sj.onc.1202611
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- Publication type:
- Article
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.
- Published in:
- Oncogene, 1999, v. 18, n. 5, p. 1219, doi. 10.1038/sj.onc.1202669
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- Publication type:
- Article
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation.
- Published in:
- Oncogene, 1998, v. 16, n. 13, p. 1723, doi. 10.1038/sj.onc.1201933
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- Publication type:
- Article
Integrative functional genomics identifies RINT1 as a novel GBM oncogene.
- Published in:
- Neuro-Oncology, 2012, v. 14, n. 11, p. 1325, doi. 10.1093/neuonc/nos246
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- Publication type:
- Article
Balanced‐PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples.
- Published in:
- Nucleic Acids Research, 2004, v. 32, n. 9, p. e76, doi. 10.1093/nar/gnh070
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- Publication type:
- Article
Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.
- Published in:
- 2016
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- Publication type:
- journal article
Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.
- Published in:
- 2015
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- Publication type:
- journal article
Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma.
- Published in:
- Journal of Clinical Investigation, 2015, v. 125, n. 8, p. 2965, doi. 10.1172/JCI77976
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- Publication type:
- Article
Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.
- Published in:
- Journal of Clinical Investigation, 2015, v. 125, n. 4, p. 1459, doi. 10.1172/JCI78954
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- Publication type:
- Article
Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.
- Published in:
- Carcinogenesis, 2008, v. 29, n. 4, p. 747, doi. 10.1093/carcin/bgn050
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- Publication type:
- Article
MTSS1 is a metastasis driver in a subset of human melanomas.
- Published in:
- Nature Communications, 2014, v. 5, n. 3, p. 3465, doi. 10.1038/ncomms4465
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- Publication type:
- Article
Semiconductor-based DNA sequencing of histone modification states.
- Published in:
- Nature Communications, 2013, v. 4, n. 10, p. 2672, doi. 10.1038/ncomms3672
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- Publication type:
- Article
HiCPlotter integrates genomic data with interaction matrices.
- Published in:
- Genome Biology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s13059-015-0767-1
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- Publication type:
- Article
Polygenic in vivo validation of cancer mutations using transposons.
- Published in:
- Genome Biology, 2014, v. 15, n. 9, p. 1, doi. 10.1186/s13059-014-0455-6
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- Publication type:
- Article
Array-CGH Reveals Recurrent Genomic Changes in Merkel Cell Carcinoma Including Amplification of L-Myc.
- Published in:
- Journal of Investigative Dermatology, 2009, v. 129, n. 6, p. 1547, doi. 10.1038/jid.2008.365
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- Publication type:
- Article
A Role for ATF2 in Regulating MITF and Melanoma Development.
- Published in:
- PLoS Pathogens, 2011, v. 7, n. 2, p. 1, doi. 10.1371/journal.pgen.1001258
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- Publication type:
- Article
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.
- Published in:
- Nature, 2000, v. 406, n. 6796, p. 641, doi. 10.1038/35020592
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- Publication type:
- Article
Amplification of CDK4 and MDM2 in malignant melanoma.
- Published in:
- Genes, Chromosomes & Cancer, 2006, v. 45, n. 5, p. 447
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- Publication type:
- Article
Clonal evolution of acute myeloid leukemia relapsed after 19 years of remission.
- Published in:
- American Journal of Hematology, 2015, v. 90, n. 7, p. E134, doi. 10.1002/ajh.24009
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- Publication type:
- Article
A Role for ATF2 in Regulating MITF and Melanoma Development.
- Published in:
- PLoS Genetics, 2010, v. 6, n. 12, p. 1, doi. 10.1371/journal.pgen.1001258
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- Publication type:
- Article
Global impact of somatic structural variation on the DNA methylome of human cancers.
- Published in:
- Genome Biology, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s13059-019-1818-9
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- Publication type:
- Article
Inhibition of melanoma development in the Nras<sup> (Q61K)</sup> :: Ink4a<sup> −/−</sup> mouse model by the small molecule BI-69A11.
- Published in:
- Pigment Cell & Melanoma Research, 2013, v. 26, n. 1, p. 136, doi. 10.1111/pcmr.12033
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- Publication type:
- Article
Essential role for oncogenic Ras in tumour maintenance.
- Published in:
- Nature, 1999, v. 400, n. 6743, p. 468, doi. 10.1038/22788
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- Publication type:
- Article
Nozzle: a report generation toolkit for data analysis pipelines.
- Published in:
- Bioinformatics, 2013, v. 29, n. 8, p. 1089, doi. 10.1093/bioinformatics/btt085
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- Publication type:
- Article
Non-germline genetically engineered mouse models for translational cancer research.
- Published in:
- 2010
- By:
- Publication type:
- journal article
The genetics of malignant melanoma: lessons from mouse and man.
- Published in:
- Nature Reviews Cancer, 2003, v. 3, n. 8, p. 559, doi. 10.1038/nrc1145
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- Publication type:
- Article