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Mechanism of sphingosine 1-phosphate clearance from blood.
Published in:
Biochemical Journal, 2020, v. 477, n. 5, p. 925, doi. 10.1042/BCJ20190730
By:
- Kharel, Yugesh;
- Tao Huang;
- Salamon, Anita;
- Harris, Thurl E.;
- Santos, Webster L.;
- Lynch, Kevin R.
Publication type:
Article
Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.
Published in:
Biochemical Journal, 2012, v. 447, n. 1, p. 149, doi. 10.1042/BJ20120609
By:
- KHAREL, Yugesh;
- RAJE, Mithun;
- GAO, Ming;
- GELLETT, Amanda M.;
- TOMSIG, Jose L.;
- LYNCH, Kevin R.;
- SANTOS, Webster L.
Publication type:
Article
Building a better sphingosine kinase-1 inhibitor.
Published in:
Biochemical Journal, 2012, v. 444, n. 1, p. e1, doi. 10.1042/BJ20120567
By:
- LYNCH, Kevin R.
Publication type:
Article
Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes.
Published in:
Kidney International, 2011, v. 79, n. 10, p. 1090, doi. 10.1038/ki.2010.544
By:
- Awad, Alaa S.;
- Rouse, Michael D.;
- Khutsishvili, Konstantine;
- Liping Huang;
- Bolton, W. Kline;
- Lynch, Kevin R.;
- Okusa, Mark D.
Publication type:
Article
Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation.
Published in:
Journal of Cell Biology, 2001, v. 153, n. 2, p. 429, doi. 10.1083/jcb.153.2.429
By:
- Dong-Soon Im;
- Heise, Christopher E.;
- Tuan Nguyen;
- O'Dowd, Brian F.;
- Lynch, Kevin R.
Publication type:
Article
Decreased Peritoneal Ovarian Cancer Growth in Mice Lacking Expression of Lipid Phosphate Phosphohydrolase 1.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120071
By:
- Nakayama, John;
- Raines, Timothy A.;
- Lynch, Kevin R.;
- Slack-Davis, Jill K.
Publication type:
Article
The Omnific Lysophospholipid Growth Factors.
Published in:
Annals of the New York Academy of Sciences, 2000, v. 905, n. 1, p. xi, doi. 10.1111/j.1749-6632.2000.tb06531.x
By:
- GOETZL, EDWARD J.;
- LYNCH, KEVIN R.
Publication type:
Article
Distribution of α2C-adrenergic receptor-like immunoreactivity in the rat central nervous system.
Published in:
Journal of Comparative Neurology, 1996, v. 372, n. 1, p. 135, doi. 10.1002/(SICI)1096-9861(19960812)372:1<135::AID-CNE9>3.0.CO;2-4
By:
- Rosin, Diane L.;
- Talley, Edmund M.;
- Lee, Amy;
- Stornetta, Ruth L.;
- Gaylinn, Bruce D.;
- Guyenet, Patrice G.;
- Lynch, Kevin R.
Publication type:
Article
Distribution of α2A-adrenergic receptor-like immunoreactivity in the rat central nervous system.
Published in:
Journal of Comparative Neurology, 1996, v. 372, n. 1, p. 111, doi. 10.1002/(SICI)1096-9861(19960812)372:1<111::AID-CNE8>3.0.CO;2-6
By:
- Talley, Edmund M.;
- Rosin, Diane L.;
- Lee, Amy;
- Guyenet, Patrice G.;
- Lynch, Kevin R.
Publication type:
Article
A Novel Sphingosine Kinase Inhibitor Suppresses Chikungunya Virus Infection.
Published in:
Viruses (1999-4915), 2022, v. 14, n. 6, p. N.PAG, doi. 10.3390/v14061123
By:
- Oyewole, Opeoluwa O.;
- Dunnavant, Kyle;
- Bhattarai, Shaurav;
- Kharel, Yugesh;
- Lynch, Kevin R.;
- Santos, Webster L.;
- Reid, St. Patrick
Publication type:
Article
Inhibition of autotaxin production or activity blocks lysophosphatidylcholine-induced migration of human breast cancer and melanoma cells.
Published in:
Molecular Carcinogenesis, 2009, v. 48, n. 9, p. 801, doi. 10.1002/mc.20524
By:
- Gaetano, Cristoforo G.;
- Samadi, Nasser;
- Tomsig, Jose L.;
- Macdonald, Timothy L.;
- Lynch, Kevin R.;
- Brindley, David N.
Publication type:
Article
Identification of receptors for neuromedin U and its role in feeding.
Published in:
Nature, 2000, v. 406, n. 6791, p. 70, doi. 10.1038/35017610
By:
- Howard, Andrew D.;
- Wang, Ruiping;
- Sheng-Shung Pong;
- Mellin, Theodore N.;
- Strack, Alison;
- Xiao-Ming Guan;
- Zhizhen Zeng;
- Williams, Jr., David L.;
- Feighner, Scott D.;
- Nunes, Christian N.;
- Murphy, Beth;
- Stair, Judith N.;
- Hong Yu;
- Quingping Jiang;
- Clements, Michelle K.;
- Tan, Carina P.;
- McKee, Karen K.;
- Hreniuk, Donna L.;
- McDonald, Terrence P.;
- Lynch, Kevin R.
Publication type:
Article
Sphingosine-1-Phosphate Reduces CD4+ T-Cell Activation in Type 1 Diabetes Through Regulation of Hypoxia-Inducible Factor Short Isoform I.1 and CD69.
Published in:
Diabetes, 2008, v. 57, n. 2, p. 484, doi. 10.2337/db07-0855
By:
- Srinivasan, Suseela;
- Bolick, David T.;
- Lukashev, Dmitriy;
- Lappas, Courtney;
- Sitkovsky, Michail;
- Lynch, Kevin R.;
- Hedrick, Catherine C.
Publication type:
Article
Characterization of α2A-Adrenergic Receptors in GT1 Neurosecretory Cells.
Published in:
Neuroendocrinology, 1995, v. 62, n. 3, p. 215, doi. 10.1159/000127007
By:
- Lee, Amy;
- Talley, Edmund;
- Rosin, Diane L.;
- Lynch, Kevin R.
Publication type:
Article
Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney.
Published in:
Science Translational Medicine, 2022, v. 14, n. 658, p. 1, doi. 10.1126/scitranslmed.abj2681
By:
- Tanaka, Shinji;
- Zheng, Shuqiu;
- Kharel, Yugesh;
- Fritzemeier, Russell G.;
- Huang, Tao;
- Foster, Daniel;
- Poudel, Nabin;
- Goggins, Eibhlin;
- Yamaoka, Yusuke;
- Rudnicka, Kinga P.;
- Lipsey, Jonathan E.;
- Radel, Hope V.;
- Ryuh, Sophia M.;
- Inoue, Tsuyoshi;
- Yao, Junlan;
- Rosin, Diane L.;
- Schwab, Susan R.;
- Santos, Webster L.;
- Lynch, Kevin R.;
- Okusa, Mark D.
Publication type:
Article
Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS.
Published in:
Journal of Neurochemistry, 2009, v. 110, n. 4, p. 1191, doi. 10.1111/j.1471-4159.2009.06202.x
By:
- Sim-Selley, Laura J.;
- Goforth, Paulette B.;
- Mba, Mba U.;
- Macdonald, Timothy L.;
- Lynch, Kevin R.;
- Milstien, Sheldon;
- Spiegel, Sarah;
- Satin, Leslie S.;
- Welch, Sandra P.;
- Selley, Dana E.
Publication type:
Article
Characterization of the human cysteinyl leukotriene CysLT1 receptor.
Published in:
Nature, 1999, v. 399, n. 6738, p. 789, doi. 10.1038/21658
By:
- Lynch, Kevin R.;
- O'Neill, Gary P.;
- Liu, Qingyun;
- Im, Dong-Soon;
- Sawyer, Nicole;
- Metters, Kathleen M.;
- Coulombe, Nathalie;
- Abramovitz, Mark;
- Figueroa, David J.;
- Zeng, Zhizhen;
- Connolly, Brett M.;
- Bai, Chang;
- Austin, Christopher P.;
- Chateauneuf, Anne;
- Stocco, Rino;
- Greig, Gillian M.;
- Kargman, Stacia;
- Hooks, Shelley B.;
- Hosfield, Elizabeth;
- William Jr., David L.
Publication type:
Article
Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors.
Published in:
PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0192179
By:
- Kharel, Yugesh;
- Agah, Sayeh;
- Huang, Tao;
- Mendelson, Anna J.;
- Eletu, Oluwafunmilayo T.;
- Barkey-Bircann, Peter;
- Gesualdi, James;
- Smith, Jeffrey S.;
- Santos, Webster L.;
- Lynch, Kevin R.
Publication type:
Article
Divergent roles of sphingosine kinases in kidney ischemia–reperfusion injury.
Published in:
Kidney International, 2009, v. 75, n. 2, p. 167, doi. 10.1038/ki.2008.400
By:
- Sang-Kyung Jo;
- Bajwa, Amandeep;
- Hong Ye;
- Vergis, Amy L.;
- Awad, Alaa S.;
- Kharel, Yugesh;
- Lynch, Kevin R.;
- Okusa, Mark D.
Publication type:
Article

Found: 19

Mechanism of sphingosine 1-phosphate clearance from blood.

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.

Building a better sphingosine kinase-1 inhibitor.

Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes.

Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation.

Decreased Peritoneal Ovarian Cancer Growth in Mice Lacking Expression of Lipid Phosphate Phosphohydrolase 1.

The Omnific Lysophospholipid Growth Factors.

Distribution of α<sub>2C</sub>-adrenergic receptor-like immunoreactivity in the rat central nervous system.

Distribution of α<sub>2A</sub>-adrenergic receptor-like immunoreactivity in the rat central nervous system.

A Novel Sphingosine Kinase Inhibitor Suppresses Chikungunya Virus Infection.

Inhibition of autotaxin production or activity blocks lysophosphatidylcholine-induced migration of human breast cancer and melanoma cells.

Identification of receptors for neuromedin U and its role in feeding.

Sphingosine-1-Phosphate Reduces CD4<sup>+</sup> T-Cell Activation in Type 1 Diabetes Through Regulation of Hypoxia-Inducible Factor Short Isoform I.1 and CD69.

Characterization of α<sub>2A</sub>-Adrenergic Receptors in GT1 Neurosecretory Cells.

Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney.

Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS.

Characterization of the human cysteinyl leukotriene CysLT1 receptor.

Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors.

Divergent roles of sphingosine kinases in kidney ischemia–reperfusion injury.