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Endothelial intercellular cell adhesion molecule 1 contributes to cell aggregate formation in CHO cells cultured in serum‐free media.
Published in:
Biotechnology Progress, 2020, v. 36, n. 3, p. 1, doi. 10.1002/btpr.2951
By:
- Louie, Salina;
- Heidersbach, Amy;
- Blanco, Noelia;
- Haley, Benjamin;
- Rose, Christopher M.;
- Liu, Peter S.;
- Yim, Mandy;
- Tang, Danming;
- Lam, Cynthia;
- Sandoval, Wendy N.;
- Shaw, David;
- Snedecor, Brad;
- Misaghi, Shahram
Publication type:
Article
Utilizing a regulated targeted integration cell line development approach to systematically investigate what makes an antibody difficult to express.
Published in:
Biotechnology Progress, 2019, v. 35, n. 2, p. N.PAG, doi. 10.1002/btpr.2772
By:
- Tadauchi, Tomofumi;
- Lam, Cynthia;
- Liu, Laura;
- Zhou, Yizhou;
- Tang, Danming;
- Louie, Salina;
- Snedecor, Brad;
- Misaghi, Shahram
Publication type:
Article
Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally‐derived or not.
Published in:
Biotechnology Progress, 2018, v. 34, n. 3, p. 559, doi. 10.1002/btpr.2560
By:
- Zhou, Yizhou;
- Shaw, David;
- Lam, Cynthia;
- Tsukuda, Joni;
- Yim, Mandy;
- Tang, Danming;
- Louie, Salina;
- Laird, Michael W.;
- Snedecor, Brad;
- Misaghi, Shahram
Publication type:
Article
Taming hyperactive h DNase I: Stable inducible expression of a hyperactive salt- and actin-resistant variant of human deoxyribonuclease I in CHO cells.
Published in:
Biotechnology Progress, 2017, v. 33, n. 2, p. 523, doi. 10.1002/btpr.2439
By:
- Lam, Cynthia;
- Santell, Lydia;
- Wilson, Blair;
- Yim, Mandy;
- Louie, Salina;
- Tang, Danming;
- Shaw, David;
- Chan, Pamela;
- Lazarus, Robert A.;
- Snedecor, Brad;
- Misaghi, Shahram
Publication type:
Article
Slashing the timelines: Opting to generate high-titer clonal lines faster via viability-based single cell sorting.
Published in:
Biotechnology Progress, 2016, v. 32, n. 1, p. 198, doi. 10.1002/btpr.2204
By:
- Misaghi, Shahram;
- Shaw, David;
- Louie, Salina;
- Nava, Adrian;
- Simmons, Laura;
- Snedecor, Brad;
- Poon, Chungkee;
- Paw, Jonathan S.;
- Gilmour‐Appling, Laurie;
- Cupp, James E.
Publication type:
Article
FX knockout CHO hosts can express desired ratios of fucosylated or afucosylated antibodies with high titers and comparable product quality.
Published in:
Biotechnology & Bioengineering, 2017, v. 114, n. 3, p. 632, doi. 10.1002/bit.26188
By:
- Louie, Salina;
- Haley, Benjamin;
- Marshall, Brett;
- Heidersbach, Amy;
- Yim, Mandy;
- Brozynski, Martina;
- Tang, Danming;
- Lam, Cynthia;
- Petryniak, Bronislawa;
- Shaw, David;
- Shim, Jeongsup;
- Miller, Aaron;
- Lowe, John B.;
- Snedecor, Brad;
- Misaghi, Shahram
Publication type:
Article
Phosphorylation of NLRC4 is critical for inflammasome activation.
Published in:
Nature, 2012, v. 490, n. 7421, p. 539, doi. 10.1038/nature11429
By:
- Qu, Yan;
- Misaghi, Shahram;
- Izrael-Tomasevic, Anita;
- Newton, Kim;
- Gilmour, Laurie L.;
- Lamkanfi, Mohamed;
- Louie, Salina;
- Kayagaki, Nobuhiko;
- Liu, Jinfeng;
- Kömüves, László;
- Cupp, James E.;
- Arnott, David;
- Monack, Denise;
- Dixit, Vishva M.
Publication type:
Article
Non-canonical inflammasome activation targets caspase-11.
Published in:
Nature, 2011, v. 479, n. 7371, p. 117, doi. 10.1038/nature10558
By:
- Kayagaki, Nobuhiko;
- Warming, Søren;
- Lamkanfi, Mohamed;
- Walle, Lieselotte Vande;
- Louie, Salina;
- Dong, Jennifer;
- Newton, Kim;
- Qu, Yan;
- Liu, Jinfeng;
- Heldens, Sherry;
- Zhang, Juan;
- Lee, Wyne P.;
- Roose-Girma, Merone;
- Dixit, Vishva M.
Publication type:
Article
Concurrent transfection of randomized transgene configurations into targeted integration CHO host is an advantageous and cost‐effective method for expression of complex molecules.
Published in:
Biotechnology Journal, 2021, v. 16, n. 4, p. 1, doi. 10.1002/biot.202000230
By:
- Dong, Emily;
- Lam, Cynthia;
- Tang, Danming;
- Louie, Salina;
- Yim, Mandy;
- Williams, Ambrose J.;
- Sawyer, William;
- Yip, Shirley;
- Carver, Joseph;
- AlBarakat, Ali;
- Tsukuda, Joni;
- Snedecor, Brad;
- Misaghi, Shahram
Publication type:
Article
Supplementation of Nucleosides During Selection can Reduce Sequence Variant Levels in CHO Cells Using GS/MSX Selection System.
Published in:
Biotechnology Journal, 2018, v. 13, n. 1, p. 1, doi. 10.1002/biot.201700335
By:
- Tang, Danming;
- Lam, Cynthia;
- Louie, Salina;
- Hoi, Kam Hon;
- Shaw, David;
- Yim, Mandy;
- Snedecor, Brad;
- Misaghi, Shahram
Publication type:
Article

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