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Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34523-y
By:
- Shah, Jennifer B.;
- Pueschl, Dana;
- Wubbenhorst, Bradley;
- Fan, Mengyao;
- Pluta, John;
- D'Andrea, Kurt;
- Hubert, Anna P.;
- Shilan, Jake S.;
- Zhou, Wenting;
- Kraya, Adam A.;
- Llop Guevara, Alba;
- Ruan, Catherine;
- Serra, Violeta;
- Balmaña, Judith;
- Feldman, Michael;
- Morin, Pat J.;
- Nayak, Anupma;
- Maxwell, Kara N.;
- Domchek, Susan M.;
- Nathanson, Katherine L.
Publication type:
Article
Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers.
Published in:
Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-34523-y
By:
- Shah, Jennifer B.;
- Pueschl, Dana;
- Wubbenhorst, Bradley;
- Fan, Mengyao;
- Pluta, John;
- D'Andrea, Kurt;
- Hubert, Anna P.;
- Shilan, Jake S.;
- Zhou, Wenting;
- Kraya, Adam A.;
- Llop Guevara, Alba;
- Ruan, Catherine;
- Serra, Violeta;
- Balmaña, Judith;
- Feldman, Michael;
- Morin, Pat J.;
- Nayak, Anupma;
- Maxwell, Kara N.;
- Domchek, Susan M.;
- Nathanson, Katherine L.
Publication type:
Article
A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 12, p. N.PAG, doi. 10.15252/emmm.201809172
By:
- Castroviejo‐Bermejo, Marta;
- Cruz, Cristina;
- Llop‐Guevara, Alba;
- Gutiérrez‐Enríquez, Sara;
- Ducy, Mandy;
- Ibrahim, Yasir Hussein;
- Gris‐Oliver, Albert;
- Pellegrino, Benedetta;
- Bruna, Alejandra;
- Guzmán, Marta;
- Rodríguez, Olga;
- Grueso, Judit;
- Bonache, Sandra;
- Moles‐Fernández, Alejandro;
- Villacampa, Guillermo;
- Viaplana, Cristina;
- Gómez, Patricia;
- Vidal, Marc;
- Peg, Vicente;
- Serres‐Créixams, Xavier
Publication type:
Article
The PARP1 selective inhibitor saruparib (AZD5305) elicits potent and durable antitumor activity in patient-derived BRCA1/2-associated cancer models.
Published in:
Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01370-z
By:
- Herencia-Ropero, Andrea;
- Llop-Guevara, Alba;
- Staniszewska, Anna D.;
- Domènech-Vivó, Joanna;
- García-Galea, Eduardo;
- Moles-Fernández, Alejandro;
- Pedretti, Flaminia;
- Domènech, Heura;
- Rodríguez, Olga;
- Guzmán, Marta;
- Arenas, Enrique J.;
- Verdaguer, Helena;
- Calero-Nieto, Fernando J.;
- Talbot, Sara;
- Tobalina, Luis;
- Leo, Elisabetta;
- Lau, Alan;
- Nuciforo, Paolo;
- Dienstmann, Rodrigo;
- Macarulla, Teresa
Publication type:
Article
A GM-CSF/IL-33 Pathway Facilitates Allergic Airway Responses to Sub-Threshold House Dust Mite Exposure.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088714
By:
- Llop-Guevara, Alba;
- Chu, Derek K.;
- Walker, Tina D.;
- Goncharova, Susanna;
- Fattouh, Ramzi;
- Silver, Jonathan S.;
- Moore, Cheryl Lynn;
- Xie, Juliana L.;
- O’Byrne, Paul M.;
- Coyle, Anthony J.;
- Kolbeck, Roland;
- Humbles, Alison A.;
- Stämpfli, Martin R.;
- Jordana, Manel
Publication type:
Article
In Vivo-to-In Silico Iterations to Investigate Aeroallergen-Host Interactions.
Published in:
PLoS ONE, 2008, v. 3, n. 6, p. 1, doi. 10.1371/journal.pone.0002426
By:
- Llop-Guevara, Alba;
- Colangelo, Marc;
- Chu, Derek K.;
- Moore, Cheryl Lynn;
- Stieber, Nicole A.;
- Walker, Tina D.;
- Goncharova, Susanna;
- Coyle, Anthony J.;
- Lundblad, Lennart K. A.;
- O'Byrne, Paul M.;
- Lovric, Miroslav;
- Jordana, Manel
Publication type:
Article
Clinical consequences of BRCA2 hypomorphism.
Published in:
NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00322-9
By:
- Castells-Roca, Laia;
- Gutiérrez-Enríquez, Sara;
- Bonache, Sandra;
- Bogliolo, Massimo;
- Carrasco, Estela;
- Aza-Carmona, Miriam;
- Montalban, Gemma;
- Muñoz-Subirana, Núria;
- Pujol, Roser;
- Cruz, Cristina;
- Llop-Guevara, Alba;
- Ramírez, María J.;
- Saura, Cristina;
- Lasa, Adriana;
- Serra, Violeta;
- Diez, Orland;
- Balmaña, Judith;
- Surrallés, Jordi
Publication type:
Article
Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition.
Published in:
NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00312-x
By:
- Aziz, Diar;
- Portman, Neil;
- Fernandez, Kristine J.;
- Lee, Christine;
- Alexandrou, Sarah;
- Llop-Guevara, Alba;
- Phan, Zoe;
- Yong, Aliza;
- Wilkinson, Ashleigh;
- Sergio, C. Marcelo;
- Ferraro, Danielle;
- Etemadmoghadam, Dariush;
- Bowtell, David D.;
- Serra, Violeta;
- Waring, Paul;
- Lim, Elgene;
- Caldon, C. Elizabeth
Publication type:
Article
BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13530-6
By:
- Wang, Yifan;
- Bernhardy, Andrea J.;
- Nacson, Joseph;
- Krais, John J.;
- Tan, Yin-Fei;
- Nicolas, Emmanuelle;
- Radke, Marc R.;
- Handorf, Elizabeth;
- Llop-Guevara, Alba;
- Balmaña, Judith;
- Swisher, Elizabeth M.;
- Serra, Violeta;
- Peri, Suraj;
- Johnson, Neil
Publication type:
Article
Cigarette Smoke Differentially Affects Eosinophilia and Remodeling in a Model of House Dust Mite Asthma.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2011, v. 45, n. 4, p. 753, doi. 10.1165/rcmb.2010-0404OC
By:
- Botelho, Fernando M.;
- Llop-Guevara, Alba;
- Trimble, Nancy J.;
- Nikota, Jake K.;
- Bauer, Carla M. T.;
- Lambert, Kristen N.;
- Kianpour, Sussan;
- Jordana, Manel;
- Stämpfli, Martin R.
Publication type:
Article
Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice.
Published in:
Arthritis Research & Therapy, 2015, v. 17, p. 1, doi. 10.1186/s13075-015-0866-0
By:
- Llop-Guevara, Alba;
- Porras, Mónica;
- Cendón, Carla;
- Di Ceglie, Irene;
- Siracusa, Francesco;
- Madarena, Federica;
- Rinotas, Vagelis;
- Gómez, Lluís;
- van Lent, Peter L.;
- Douni, Eleni;
- Hyun Dong Chang;
- Kamradt, Thomas;
- Román, Juan
Publication type:
Article
Prevalence of Homologous Recombination Deficiency Among Patients With Germline RAD51C/D Breast or Ovarian Cancer.
Published in:
JAMA Network Open, 2024, v. 7, n. 1, p. e247811, doi. 10.1001/jamanetworkopen.2024.7811
By:
- Torres-Esquius, Sara;
- Llop-Guevara, Alba;
- Gutiérrez-Enríquez, Sara;
- Romey, Marcel;
- Teulé, Àlex;
- Llort, Gemma;
- Herrero, Ana;
- Sánchez-Henarejos, Pilar;
- Vallmajó, Anna;
- González-Santiago, Santiago;
- Chirivella, Isabel;
- Cano, Juana Maria;
- Graña, Begoña;
- Simonetti, Sara;
- Díaz de Corcuera, Isabela;
- Ramon y Cajal, Teresa;
- Sanz, Judit;
- Serrano, Sara;
- Otero, Andrea;
- Churruca, Cristina
Publication type:
Article
RAD51 as a biomarker for homologous recombination deficiency in high‐grade serous ovarian carcinoma: robustness and interobserver variability of the RAD51 test.
Published in:
Journal of Pathology: Clinical Research, 2023, v. 9, n. 6, p. 442, doi. 10.1002/cjp2.336
By:
- Kramer, Claire JH;
- Llop‐Guevara, Alba;
- Yaniz‐Galende, Elisa;
- Pellegrino, Benedetta;
- ter Haar, Natalja T;
- Herencia‐Ropero, Andrea;
- Campanini, Nicoletta;
- Musolino, Antonino;
- Bosse, Tjalling;
- Leary, Alexandra;
- Serra, Violeta;
- Vreeswijk, Maaike PG
Publication type:
Article
Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma.
Published in:
Allergy, Asthma & Clinical Immunology, 2015, v. 11, n. 1, p. 1, doi. 10.1186/s13223-015-0081-1
By:
- Chu, Derek K.;
- Al-Garawi, Amal;
- Llop-Guevara, Alba;
- Pillai, Regina A.;
- Radford, Katherine;
- Shen, Pamela;
- Walker, Tina D.;
- Goncharova, Susanna;
- Calhoun, William J.;
- Nair, Parameswaran;
- Jordana, Manel
Publication type:
Article
Genetic and functional homologous repair deficiency as biomarkers for platinum sensitivity in TNBC: A case report.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.963728
By:
- Gomez-Puerto, Diego;
- Llop-Guevara, Alba;
- Cruellas, Mara;
- Torres-Esquius, Sara;
- De La Torre, Javier;
- Peg, Vicente;
- Balmaña, Judith;
- Pimentel, Isabel
Publication type:
Article
Activity of HSP90 Inhibiton in a Metastatic Lung Cancer Patient With a Germline BRCA1 Mutation.
Published in:
2018
By:
- Cedrés, Susana;
- Felip, Enriqueta;
- Cruz, Cristina;
- Castro, Ana Martinez de;
- Pardo, Nuria;
- Navarro, Alejandro;
- Martinez-Marti, Alex;
- Remon, Jordin;
- Zeron-Medina, Jorge;
- Balmaña, Judith;
- Martinez de Castro, Ana;
- Llop-Guevara, Alba;
- Miquel, Josep M;
- Sansano, Irene;
- Nuciforo, Paolo;
- Mancuso, Francesco;
- Serra, Violeta;
- Vivancos, Ana
Publication type:
journal article

Found: 16