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A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 11, p. 2792, doi. 10.1093/jac/dkae246
By:
- Sandoe, Jonathan A T;
- Grozeva, Detelina;
- Albur, Mahableshwar;
- Bond, Stuart E;
- Brookes-Howell, Lucy;
- Dark, Paul;
- Euden, Joanne;
- Hamilton, Ryan;
- Hellyer, Thomas P;
- Henley, Josie;
- Hopkins, Susan;
- Howard, Philip;
- Howdon, Daniel;
- Knox-Macaulay, Chikezie;
- Llewelyn, Martin J;
- Maboshe, Wakunyambo;
- McCullagh, Iain J;
- Ogden, Margaret;
- Parsons, Helena K;
- Partridge, David G
Publication type:
Article
Procalcitonin Evaluation of Antibiotic Use in COVID-19 Hospitalised Patients (PEACH): Protocol for a Retrospective Observational Study.
Published in:
Methods & Protocols, 2022, v. 5, n. 6, p. 95, doi. 10.3390/mps5060095
By:
- Euden, Joanne;
- Pallmann, Philip;
- Grozeva, Detelina;
- Albur, Mahableshwar;
- Bond, Stuart E.;
- Brookes-Howell, Lucy;
- Dark, Paul;
- Hellyer, Thomas;
- Hopkins, Susan;
- Howard, Philip;
- Llewelyn, Martin J.;
- Maboshe, Wakunyambo;
- McCullagh, Iain J.;
- Ogden, Margaret;
- Parsons, Helena;
- Partridge, David;
- Powell, Neil;
- Shaw, Dominick;
- Shinkins, Bethany;
- Szakmany, Tamas
Publication type:
Article
Authors' Reply to Hays: "A Multinational European Study of Patient Preferences for Novel Diagnostics to Manage Antimicrobial Resistance".
Published in:
2020
By:
- Mott, David J.;
- Hampson, Grace;
- Llewelyn, Martin J.;
- Mestre-Ferrandiz, Jorge;
- Hopkins, Michael M.
Publication type:
Letter
A Multinational European Study of Patient Preferences for Novel Diagnostics to Manage Antimicrobial Resistance.
Published in:
Applied Health Economics & Health Policy, 2020, v. 18, n. 1, p. 69, doi. 10.1007/s40258-019-00516-0
By:
- Mott, David J.;
- Hampson, Grace;
- Llewelyn, Martin J.;
- Mestre-Ferrandiz, Jorge;
- Hopkins, Michael M.
Publication type:
Article
Use of Procalcitonin during the First Wave of COVID-19 in the Acute NHS Hospitals: A Retrospective Observational Study.
Published in:
Antibiotics (2079-6382), 2021, v. 10, n. 5, p. 516, doi. 10.3390/antibiotics10050516
By:
- Powell, Neil;
- Howard, Philip;
- Llewelyn, Martin J.;
- Szakmany, Tamas;
- Albur, Mahableswhar;
- Bond, Stuart E;
- Euden, Joanne;
- Brookes-Howell, Lucy;
- Dark, Paul;
- Hellyer, Thomas P;
- Hopkins, Susan;
- McCullagh, Iain J;
- Ogden, Margaret;
- Pallmann, Philip;
- Parsons, Helena;
- Partridge, David G;
- Shaw, Dominick E.;
- Shinkins, Bethany;
- Todd, Stacy;
- Thomas-Jones, Emma
Publication type:
Article
Severe infections emerge from commensal bacteria by adaptive evolution.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.30637
By:
- Young, Bernadette C.;
- Chieh-Hsi Wu;
- Gordon, N. Claire;
- Cole, Kevin;
- Pric, James R.;
- Liu, Elian;
- Sheppard, Anna E.;
- Perera, Sanuki;
- Charlesworth, Jane;
- Golubchik, Tanya;
- Iqbal, Zamin;
- Bowden, Rory;
- Massey, Ruth C.;
- Paul, John;
- Crook, Derrick W.;
- Peto, Timothy E.;
- Walker, A. Sarah;
- Llewelyn, Martin J.;
- Wyllie, David H.;
- Wilson, Daniel J.
Publication type:
Article
Why do hospital prescribers continue antibiotics when it is safe to stop? Results of a choice experiment survey.
Published in:
2020
By:
- Roope, Laurence S. J.;
- Buchanan, James;
- Morrell, Liz;
- Pouwels, Koen B.;
- Sivyer, Katy;
- Mowbray, Fiona;
- Abel, Lucy;
- Cross, Elizabeth L. A.;
- Yardley, Lucy;
- Peto, Tim;
- Walker, A. Sarah;
- Llewelyn, Martin J.;
- Wordsworth, Sarah
Publication type:
journal article
Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial.
Published in:
PLoS Medicine, 2024, v. 21, n. 9, p. 1, doi. 10.1371/journal.pmed.1004428
By:
- Schilling, William H. K.;
- Mukaka, Mavuto;
- Callery, James J.;
- Llewelyn, Martin J.;
- Cruz, Cintia V.;
- Dhorda, Mehul;
- Ngernseng, Thatsanun;
- Waithira, Naomi;
- Ekkapongpisit, Maneerat;
- Watson, James A.;
- Chandna, Arjun;
- Nelwan, Erni J.;
- Hamers, Raph L.;
- Etyang, Anthony;
- Beg, Mohammad Asim;
- Sow, Samba;
- Yavo, William;
- Allabi, Aurel Constant;
- Basnyat, Buddha;
- Sharma, Sanjib Kumar
Publication type:
Article
Discriminative performance of pancreatic stone protein in predicting ICU mortality and infection severity in adult patients with infection: a systematic review and individual patient level meta-analysis.
Published in:
Infection, 2023, v. 51, n. 6, p. 1797, doi. 10.1007/s15010-023-02093-w
By:
- Zuercher, Patrick;
- Moser, André;
- Garcia de Guadiana-Romualdo, Luis;
- Llewelyn, Martin J.;
- Graf, Rolf;
- Reding, Theresia;
- Eggimann, Philippe;
- Que, Yok-Ai;
- Prazak, Josef
Publication type:
Article
Circulating Plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS).
Published in:
Scientific Reports, 2016, p. 28006, doi. 10.1038/srep28006
By:
- Caserta, Stefano;
- Kern, Florian;
- Cohen, Jonathan;
- Drage, Stephen;
- Newbury, Sarah F.;
- Llewelyn, Martin J.
Publication type:
Article
Severity of Systemic Inflammatory Response Syndrome Affects the Blood Levels of Circulating Inflammatory-Relevant MicroRNAs.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2017.01977
By:
- Caserta, Stefano;
- Mengozzi, Manuela;
- Kern, Florian;
- Newbury, Sarah F.;
- Ghezzi, Pietro;
- Llewelyn, Martin J.
Publication type:
Article
How is diarrhoea managed in UK care homes? A survey with implications for recognition and control of Clostridium difficile infection.
Published in:
Journal of Public Health, 2010, v. 32, n. 4, p. 472, doi. 10.1093/pubmed/fdq036
By:
- Henderson, Hazel J.;
- Maddock, Liz;
- Andrews, Sue;
- Trail, Peter;
- Loades, Nancy;
- Purcell, Bernadette;
- Iversen, Angela;
- Llewelyn, Martin J.;
- Cassell, Jackie A.
Publication type:
Article
Probiotics for the prevention and treatment of Clostridium difficile in older patients.
Published in:
Age & Ageing, 2012, v. 41, n. 6, p. 706, doi. 10.1093/ageing/afs077
By:
- Islam, Jasmin;
- Cohen, Jonathan;
- Rajkumar, Chakravarthi;
- Llewelyn, Martin J.
Publication type:
Article
What is the Diagnostic Accuracy of Novel Urine Biomarkers for Urinary Tract Infection?
Published in:
Biomarker Insights, 2023, p. 1, doi. 10.1177/11772719221144459
By:
- Edwards, George;
- Seeley, Anna;
- Carter, Adam;
- Patrick Smith, Maia;
- Cross, Elizabeth LA;
- Hughes, Kathryn;
- Van den Bruel, Ann;
- Llewelyn, Martin J;
- Verbakel, Jan Y;
- Hayward, Gail
Publication type:
Article
What is the Diagnostic Accuracy of Novel Urine Biomarkers for Urinary Tract Infection?
Published in:
Biomarker Insights, 2023, v. 18, p. 1, doi. 10.1177/11772719221144459
By:
- Edwards, George;
- Seeley, Anna;
- Carter, Adam;
- Smith, Maia Patrick;
- Cross, Elizabeth L. A.;
- Hughes, Kathryn;
- den Bruel, Ann Van;
- Llewelyn, Martin J.;
- Verbakel, Jan Y.;
- Hayward, Gail
Publication type:
Article
Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care.
Published in:
Critical Care, 2013, v. 17, n. 2, p. 2, doi. 10.1186/cc12588
By:
- Llewelyn, Martin J.;
- Berger, Mario;
- Gregory, Mark;
- Ramaiah, Ravi;
- Taylor, Amanda L.;
- Curdt, Ingo;
- Lajaunias, Frédéric;
- Graf, Rolf;
- Blincko, Stuart J.;
- Drage, Stephen;
- Cohen, Jonathan
Publication type:
Article
The impact of diagnostic microbiology on de-escalation of antimicrobial therapy in hospitalised adults.
Published in:
2020
By:
- Hamilton, William L.;
- Pires, Sacha-Marie;
- Lippett, Samantha;
- Gudka, Vikesh;
- Cross, Elizabeth L. A.;
- Llewelyn, Martin J.
Publication type:
journal article
Mathematical modelling for antibiotic resistance control policy: do we know enough?
Published in:
2019
By:
- Knight, Gwenan M.;
- Davies, Nicholas G.;
- Colijn, Caroline;
- Coll, Francesc;
- Donker, Tjibbe;
- Gifford, Danna R.;
- Glover, Rebecca E.;
- Jit, Mark;
- Klemm, Elizabeth;
- Lehtinen, Sonja;
- Lindsay, Jodi A.;
- Lipsitch, Marc;
- Llewelyn, Martin J.;
- Mateus, Ana L. P.;
- Robotham, Julie V.;
- Sharland, Mike;
- Stekel, Dov;
- Yakob, Laith;
- Atkins, Katherine E.
Publication type:
journal article
Selective culture enrichment and sequencing of feces to enhance detection of antimicrobial resistance genes in third-generation cephalosporin resistant Enterobacteriaceae.
Published in:
PLoS ONE, 2019, v. 14, n. 11, p. 1, doi. 10.1371/journal.pone.0222831
By:
- Peto, Leon;
- Fawcett, Nicola J.;
- Crook, Derrick W.;
- Peto, Tim E. A.;
- Llewelyn, Martin J.;
- Walker, A. Sarah
Publication type:
Article
Where now for infection services in the NHS? How lessons from the pandemic should drive long-overdue integration of microbiology and infectious diseases.
Published in:
Clinical Medicine, 2022, v. 22, n. 6, p. 586, doi. 10.7861/clinmed.2022-0251
By:
- Llewelyn, Martin J.;
- Price, Nicholas;
- Ratnaraja, Natasha;
- Atkins, Bridget;
- Partridge, David;
- Jeffery, Katie
Publication type:
Article
Reply to Mills and Linkin.
Published in:
2014
By:
- Price, James R.;
- Golubchik, Tanya;
- Wilson, Daniel J.;
- Crook, Derrick W.;
- Walker, A. Sarah;
- Peto, Timothy E. A.;
- Paul, John;
- Llewelyn, Martin J.
Publication type:
Letter to the Editor
Whole-Genome Sequencing Shows That Patient-to-Patient Transmission Rarely Accounts for Acquisition of Staphylococcus aureus in an Intensive Care Unit.
Published in:
Clinical Infectious Diseases, 2014, v. 58, n. 5, p. 609, doi. 10.1093/cid/cit807
By:
- Price, James R.;
- Golubchik, Tanya;
- Cole, Kevin;
- Wilson, Daniel J.;
- Crook, Derrick W.;
- Thwaites, Guy E.;
- Bowden, Rory;
- Walker, A. Sarah;
- Peto, Timothy E. A.;
- Paul, John;
- Llewelyn, Martin J.
Publication type:
Article
Microbial diversity and antimicrobial resistance in faecal samples from acute medical patients assessed through metagenomic sequencing.
Published in:
PLoS ONE, 2023, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0282584
By:
- Yokoyama, Maho;
- Peto, Leon;
- Budgell, Eric P.;
- Jones, Nicola;
- Sheridan, Elizabeth;
- Liu, Jane;
- Walker, A. Sarah;
- Stoesser, Nicole;
- Gweon, Hyun S.;
- Llewelyn, Martin J.
Publication type:
Article
Induction of contact-dependent CD8<sup>+</sup> regulatory T cells through stimulation with staphylococcal and streptococcal superantigens.
Published in:
Immunology, 2012, v. 135, n. 2, p. 158, doi. 10.1111/j.1365-2567.2011.03529.x
By:
- Taylor, Amanda L.;
- Cross, Elizabeth L. A.;
- Llewelyn, Martin J.
Publication type:
Article
Endothelial and inflammatory pathophysiology in dengue shock: New insights from a prospective cohort study in Vietnam.
Published in:
PLoS Neglected Tropical Diseases, 2024, v. 18, n. 3, p. 1, doi. 10.1371/journal.pntd.0012071
By:
- McBride, Angela;
- Duyen, Huynh Thi Le;
- Vuong, Nguyen Lam;
- Tho, Phan Vinh;
- Tai, Luong Thi Hue;
- Phong, Nguyen Thanh;
- Ngoc, Nguyen Thanh;
- Yen, Lam Minh;
- Nhat, Phung Tran Huy;
- Vi, Tran Thuy;
- Llewelyn, Martin J.;
- Thwaites, Louise;
- Hao, Nguyen Van;
- Yacoub, Sophie
Publication type:
Article
Accuracy of pancreatic stone protein for the diagnosis of infection in hospitalized adults: a systematic review and individual patient level meta-analysis.
Published in:
2021
By:
- Prazak, Josef;
- Irincheeva, Irina;
- Llewelyn, Martin J.;
- Stolz, Daiana;
- García de Guadiana Romualdo, Luis;
- Graf, Rolf;
- Reding, Theresia;
- Klein, Holger J.;
- Eggimann, Philippe;
- Que, Yok-Ai
Publication type:
journal article
Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data-authors' response.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 11, p. 3211, doi. 10.1093/jac/dkac315
By:
- Llewelyn, Martin J;
- West, Robert M;
- Carrol, Enitan D;
- Pallmann, Philip;
- Sandoe, Jonathan A T
Publication type:
Article
Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 4, p. 1189, doi. 10.1093/jac/dkac017
By:
- Llewelyn, Martin J.;
- Grozeva, Detelina;
- Howard, Philip;
- Euden, Joanne;
- Gerver, Sarah M.;
- Hope, Russell;
- Heginbothom, Margaret;
- Powell, Neil;
- Richman, Colin;
- Shaw, Dominick;
- Thomas-Jones, Emma;
- West, Robert M.;
- Carrol, Enitan D.;
- Pallmann, Philip;
- Sandoe, Jonathan A. T.
Publication type:
Article
Impact of recurrent Clostridium difficile infection: hospitalization and patient quality of life.
Published in:
2017
By:
- Wilcox, Mark H.;
- Ahir, Harblas;
- Coia, John E.;
- Dodgson, Andrew;
- Hopkins, Susan;
- Llewelyn, Martin J.;
- Settle, Chris;
- Mclain-Smith, Susan;
- Marcella, Stephen W.
Publication type:
journal article
Re-emergence of methicillin susceptibility in a resistant lineage of Staphylococcus aureus.
Published in:
2017
By:
- Ledda, Alice;
- Price, James R.;
- Cole, Kevin;
- Llewelyn, Martin J.;
- Kearns, Angela M.;
- Crook, Derrick W.;
- Paul, John;
- Didelot, Xavier
Publication type:
journal article
Antibiotic policies in acute English NHS trusts: implementation of 'Start Smart--Then Focus' and relationship with Clostridium difficile infection rates.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2015, v. 70, n. 4, p. 1230, doi. 10.1093/jac/dku515
By:
- Llewelyn, Martin J.;
- Hand, Kieran;
- Hopkins, Susan;
- Walker, A. Sarah
Publication type:
Article
Patient engagement with antibiotic messaging in secondary care: a qualitative feasibility study of the 'review and revise' experience.
Published in:
Pilot & Feasibility Studies, 2020, v. 6, n. 1, p. 1, doi. 10.1186/s40814-020-00590-5
By:
- Mowbray, Fiona;
- Sivyer, Katy;
- Santillo, Marta;
- Jones, Nicola;
- Peto, Tim E. A.;
- Walker, A. Sarah;
- Llewelyn, Martin J.;
- Yardley, Lucy
Publication type:
Article
Overview of systematic reviews assessing the evidence for shorter versus longer duration antibiotic treatment for bacterial infections in secondary care.
Published in:
PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194858
By:
- Onakpoya, Igho J.;
- Walker, A. Sarah;
- Tan, Pui S.;
- Spencer, Elizabeth A.;
- Gbinigie, Oghenekome A.;
- Cook, Johanna;
- Llewelyn, Martin J.;
- Butler, Christopher C.
Publication type:
Article
Predictors of Death after Clostridium difficile Infection: A Report on 128 Strain-Typed Cases from a Teaching Hospital in the United Kingdom.
Published in:
Clinical Infectious Diseases, 2010, v. 50, n. 12, p. e77, doi. 10.1086/653012
By:
- Wilson, Vhairi;
- Cheek, Liz;
- Satta, Giovanni;
- Walker-Bone, Karen;
- Cubbon, Marc;
- Citron, Diane;
- Gerding, Dale N.;
- Llewelyn, Martin J.
Publication type:
Article
Tracking the Microbes in Sepsis: Advancements in Treatment Bring Challenges for Microbial Epidemiology.
Published in:
Clinical Infectious Diseases, 2007, v. 44, n. 10, p. 1343, doi. 10.1086/515403
By:
- Llewelyn, Martin J.;
- Cohen, Jonathan
Publication type:
Article
A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials.
Published in:
2022
By:
- McBride, Angela;
- Vuong, Nguyen Lam;
- Van Hao, Nguyen;
- Huy, Nguyen Quang;
- Chanh, Ho Quang;
- Chau, Nguyen Thi Xuan;
- Nguyet, Nguyen Minh;
- Ming, Damien K.;
- Ngoc, Nguyen Thanh;
- Nhat, Phung Tran Huy;
- Phong, Nguyen Thanh;
- Tai, Luong Thi Hue;
- Tho, Phan Vinh;
- Trung, Dinh The;
- Tam, Dong Thi Hoai;
- Trieu, Huynh Trung;
- Geskus, Ronald Bertus;
- Llewelyn, Martin J.;
- Thwaites, C. Louise;
- Yacoub, Sophie
Publication type:
journal article

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