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Predicting EGFR mutational status from pathology images using a real-world dataset.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-31284-6
By:
- Pao, James J.;
- Biggs, Mikayla;
- Duncan, Daniel;
- Lin, Douglas I.;
- Davis, Richard;
- Huang, Richard S. P.;
- Ferguson, Donna;
- Janovitz, Tyler;
- Hiemenz, Matthew C.;
- Eddy, Nathanial R.;
- Lehnert, Erik;
- Cabili, Moran N.;
- Frampton, Garrett M.;
- Hegde, Priti S.;
- Albacker, Lee A.
Publication type:
Article
Precision needle-punch tumor enrichment from paraffin blocks improves the detection of clinically actionable genomic alterations and biomarkers.
Published in:
Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1328512
By:
- Lin, Douglas I.;
- Huang, Richard S. P.;
- Ladas, Ioannis;
- Keller, Rachel B.;
- Patel, Nimesh R.;
- Lakis, Sotirios;
- Decker, Brennan;
- Janovitz, Tyler;
- Mata, Douglas A.;
- Ross, Jeffrey S.;
- Vergilio, Jo-Anne;
- Elvin, Julia A.;
- Herbst, Roy S.;
- Mack, Philip C.;
- Killian, Jonathan K.
Publication type:
Article
POU2AF3‐rearranged sarcomas: A novel tumor defined by fusions of EWSR1 or FUS to a gene formerly designated COLCA2.
Published in:
Genes, Chromosomes & Cancer, 2023, v. 62, n. 8, p. 460, doi. 10.1002/gcc.23136
By:
- Hiemenz, Matthew C.;
- Kaur, Jaspreet;
- Kuang, Zheng;
- Huang, Richard S. P.;
- Harries, Lukas;
- Metzger, Dana;
- Schiavone, Kelsie;
- Millis, Sherri Z.;
- Lin, Douglas I.;
- Lechpammer, Mirna;
- Decker, Brennan;
- Mata, Douglas A.;
- Reddy, Abhinav;
- Parke, Matthew;
- Lee, Eun Y.;
- Cui, Xiaoyan;
- Iwenofu, O. Hans;
- Buehler, Darya;
- Henderson, Les;
- Baldwin, Erin M.
Publication type:
Article
Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy by Tumor Mutational Burden in Metastatic Castration-Resistant Prostate Cancer.
Published in:
JAMA Network Open, 2022, v. 5, n. 3, p. e225394, doi. 10.1001/jamanetworkopen.2022.5394
By:
- Graf, Ryon P.;
- Fisher, Virginia;
- Weberpals, Janick;
- Gjoerup, Ole;
- Tierno, Marni B.;
- Huang, Richard S. P.;
- Sayegh, Nicolas;
- Lin, Douglas I.;
- Raskina, Kira;
- Schrock, Alexa B.;
- Severson, Eric;
- Haberberger, James F.;
- Ross, Jeffrey S.;
- Creeden, James;
- Levy, Mia A.;
- Alexander, Brian M.;
- Oxnard, Geoffrey R.;
- Agarwal, Neeraj
Publication type:
Article
Pan-tumor validation of a NGS fraction-based MSI analysis as a predictor of response to Pembrolizumab.
Published in:
NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00679-7
By:
- Lin, Douglas I.;
- Quintanilha, Julia C. F.;
- Danziger, Natalie;
- Lang, Lixin;
- Levitan, Diane;
- Hayne, Cynthia;
- Hiemenz, Matthew C.;
- Smith, David L.;
- Albacker, Lee A.;
- Leibowitz, Jeffrey;
- Mata, Douglas A.;
- Decker, Brennan;
- Lakis, Sotirios;
- Patel, Nimesh R.;
- Graf, Ryon P.;
- Elvin, Julia A.;
- Ross, Jeffrey S.;
- Pattani, Varun;
- Huang, Richard S. P.;
- Wehn, Amy K.
Publication type:
Article
Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational Burden.
Published in:
JAMA Network Open, 2023, v. 6, n. 12, p. e2348002, doi. 10.1001/jamanetworkopen.2023.48002
By:
- Necchi, Andrea;
- Spiess, Philippe E.;
- Costa de Padua, Tiago;
- Li, Roger;
- Grivas, Petros;
- Huang, Richard S. P.;
- Lin, Douglas I.;
- Danziger, Natalie;
- Ross, Jeffrey S.;
- Jacob, Joseph M.;
- Sager, Rebecca A.;
- Basnet, Alina;
- Li, Gerald;
- Graf, Ryon P.;
- Pavlick, Dean C.;
- Bratslavsky, Gennady
Publication type:
Article
Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy in Patients With Metastatic Colorectal Cancer With Measures of Microsatellite Instability, Mismatch Repair, or Tumor Mutational Burden.
Published in:
JAMA Network Open, 2023, v. 6, n. 1, p. e2252244, doi. 10.1001/jamanetworkopen.2022.52244
By:
- Quintanilha, Julia C. F.;
- Graf, Ryon P.;
- Fisher, Virginia A.;
- Oxnard, Geoffrey R.;
- Ellis, Haley;
- Panarelli, Nicole;
- Lin, Douglas I.;
- Li, Gerald;
- Huang, Richard S. P.;
- Ross, Jeffrey S.;
- Myer, Parvathi A.;
- Klempner, Samuel J.
Publication type:
Article
Automated clear cell renal carcinoma grade classification with prognostic significance.
Published in:
PLoS ONE, 2019, v. 14, n. 10, p. 1, doi. 10.1371/journal.pone.0222641
By:
- Tian, Katherine;
- Rubadue, Christopher A.;
- Lin, Douglas I.;
- Veta, Mitko;
- Pyle, Michael E.;
- Irshad, Humayun;
- Heng, Yujing J.
Publication type:
Article
Circulating Cell-Free DNA Yield and Circulating-Tumor DNA Quantity from Liquid Biopsies of 12 139 Cancer Patients.
Published in:
Clinical Chemistry, 2021, v. 67, n. 11, p. 1554, doi. 10.1093/clinchem/hvab176
By:
- Huang, Richard S. P.;
- Jinpeng Xiao;
- Pavlick, Dean C.;
- Cui Guo;
- Lei Yang;
- Jin, Dexter X.;
- Fendler, Bernard;
- Severson, Eric;
- Killian, Jonathan Keith;
- Hiemenz, Matthew;
- Duncan, Daniel;
- Lin, Douglas I.;
- Dennis, Lucas;
- Aiyer, Aparna;
- Gjoerup, Ole;
- Oxnard, Geoff;
- Venstrom, Jeffrey;
- Julia Elvin;
- Ramkissoon, Shakti H.;
- Ross, Jeffrey S.
Publication type:
Article
Amplification of the NSD3-BRD4-CHD8 pathway in pelvic high-grade serous carcinomas of tubo-ovarian and endometrial origin.
Published in:
Molecular & Clinical Oncology, 2017, v. 7, n. 2, p. 301, doi. 10.3892/mco.2017.1289
By:
- JONES, DEREK H.;
- LIN, DOUGLAS I.
Publication type:
Article
Amplification of the bromodomain-containing protein 4 gene in ovarian high-grade serous carcinoma is associated with worse prognosis and survival.
Published in:
Molecular & Clinical Oncology, 2015, v. 3, n. 6, p. 1291, doi. 10.3892/mco.2015.622
By:
- UCAR, DUYGU;
- LIN, DOUGLAS I.
Publication type:
Article
SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy.
Published in:
Cell Division, 2007, v. 2, p. 2, doi. 10.1186/1747-1028-2-2
By:
- Barbash, Olena;
- Lin, Douglas I.;
- Diehl, J. Alan
Publication type:
Article
Urothelial cancer harbours EGFR and HER2 amplifications and exon 20 insertions.
Published in:
BJU International, 2020, v. 125, n. 5, p. 739, doi. 10.1111/bju.15006
By:
- Madison, Russell W.;
- Gupta, Sumati V.;
- Elamin, Yasir Y.;
- Lin, Douglas I.;
- Pal, Sumanta K.;
- Necchi, Andrea;
- Miller, Vincent A.;
- Ross, Jeffrey S.;
- Chung, Jon H.;
- Alexander, Brian M.;
- Schrock, Alexa B.;
- Heymach, John V.;
- Reddy, Prasanth;
- Ali, Siraj M.
Publication type:
Article
Genomic landscape of 891 RET fusions detected across diverse solid tumor types.
Published in:
NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00347-2
By:
- Parimi, Vamsi;
- Tolba, Khaled;
- Danziger, Natalie;
- Kuang, Zheng;
- Sun, Daokun;
- Lin, Douglas I.;
- Hiemenz, Matthew C.;
- Schrock, Alexa B.;
- Ross, Jeffrey S.;
- Oxnard, Geoffrey R.;
- Huang, Richard S. P.
Publication type:
Article
Prevalence of High-Risk Nonvaccine Human Papillomavirus Types in Advanced Squamous Cell Carcinoma Among Individuals of African vs Non-African Ancestry.
Published in:
JAMA Network Open, 2021, v. 4, n. 5, p. e216481, doi. 10.1001/jamanetworkopen.2021.6481
By:
- Williams, Erik A.;
- Newberg, Justin;
- Williams, Kevin Jon;
- Montesion, Meagan;
- Alexander, Brian M.;
- Lin, Douglas I.;
- Elvin, Julia A.
Publication type:
Article
High grade serous ovarian carcinomas originate in the fallopian tube.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00962-1
By:
- Labidi-Galy, S. Intidhar;
- Papp, Eniko;
- Hallberg, Dorothy;
- Niknafs, Noushin;
- Adleff, Vilmos;
- Noe, Michael;
- Bhattacharya, Rohit;
- Novak, Marian;
- Jones, Siân;
- Phallen, Jillian;
- Hruban, Carolyn A.;
- Hirsch, Michelle S.;
- Lin, Douglas I.;
- Schwartz, Lauren;
- Maire, Cecile L.;
- Tille, Jean-Christophe;
- Bowden, Michaela;
- Ayhan, Ayse;
- Wood, Laura D.;
- Scharpf, Robert B.
Publication type:
Article
Frequency and Nature of Genomic Alterations in ERBB2-Altered Urothelial Bladder Cancer.
Published in:
Targeted Oncology, 2024, v. 19, n. 3, p. 447, doi. 10.1007/s11523-024-01056-x
By:
- Leary, Jacob B.;
- Enright, Thomas;
- Bakaloudi, Dimitra Rafailia;
- Basnet, Alina;
- Bratslavsky, Gennady;
- Jacob, Joseph;
- Spiess, Philippe E.;
- Li, Roger;
- Necchi, Andrea;
- Kamat, Ashish M.;
- Pavlick, Dean C.;
- Danziger, Natalie;
- Huang, Richard S. P.;
- Lin, Douglas I.;
- Cheng, Liang;
- Ross, Jeffrey;
- Talukder, Rafee;
- Grivas, Petros
Publication type:
Article
Hepatocellular Adenoma of the Placenta With Updated Immunohistochemical and Molecular Markers.
Published in:
International Journal of Surgical Pathology, 2016, v. 24, n. 7, p. 640, doi. 10.1177/1066896916645186
By:
- Yee, Eric U.;
- Hale, Gillian;
- Liu, Xinxin;
- Lin, Douglas I.
Publication type:
Article
Targeted Screening With Combined Age- and Morphology-Based Criteria Enriches Detection of Lynch Syndrome in Endometrial Cancer.
Published in:
International Journal of Surgical Pathology, 2016, v. 24, n. 4, p. 297, doi. 10.1177/1066896916629782
By:
- Lin, Douglas I.;
- Hecht, Jonathan L.
Publication type:
Article
Characterization of Clinical Cases of Malignant PEComa via Comprehensive Genomic Profiling of DNA and RNA.
Published in:
Oncology, 2020, v. 98, n. 12, p. 905, doi. 10.1159/000510241
By:
- Akumalla, Saranya;
- Madison, Russell;
- Lin, Douglas I.;
- Schrock, Alexa B.;
- Yakirevich, Evgeny;
- Rosenzweig, Mark;
- Balar, Arjun V.;
- Frampton, Garrett M.;
- Edgerly, Claire;
- Erlich, Rachel L.;
- Miller, Vincent A.;
- Ganesan, Shridar;
- Ross, Jeffrey S.;
- Ali, Siraj M.
Publication type:
Article
Variable Genomic Landscapes of Advanced Melanomas with Heavy Pigmentation.
Published in:
Oncologist, 2022, v. 27, n. 8, p. 655, doi. 10.1093/oncolo/oyac090
By:
- Huang, Richard S P;
- Tse, Julie Y;
- Harries, Lukas;
- Graf, Ryon P;
- Lin, Douglas I;
- Murugesan, Karthikeyan;
- Hiemenz, Matthew C;
- Parimi, Vamsi;
- Janovitz, Tyler;
- Decker, Brennan;
- Severson, Eric;
- Levy, Mia A;
- Ramkissoon, Shakti H;
- Elvin, Julia A;
- Ross, Jeffrey S;
- Williams, Erik A
Publication type:
Article
Clinicopathologic and Genomic Characterization of PD‐L1 Positive Urothelial Carcinomas.
Published in:
Oncologist, 2021, v. 26, n. 5, p. 375, doi. 10.1002/onco.13753
By:
- Huang, Richard S.P.;
- Haberberger, James;
- Harries, Lukas;
- Severson, Eric;
- Duncan, Daniel L.;
- Ferguson, N. Lynn;
- Hemmerich, Amanda;
- Edgerly, Claire;
- Murugesan, Karthikeyan;
- Xiao, Jinpeng;
- McEwan, Deborah;
- Holmes, Oliver;
- Hiemenz, Matthew;
- Venstrom, Jeffrey;
- Elvin, Julia A.;
- Creeden, James;
- Lin, Douglas I.;
- Ross, Jeffrey S.;
- Ramkissoon, Shakti H.
Publication type:
Article
Improved survival associated with somatic PIK3CA mutations in copy-number low endometrioid endometrial adenocarcinoma.
Published in:
Oncology Letters, 2015, v. 10, n. 5, p. 2743, doi. 10.3892/ol.2015.3702
By:
- LIN, DOUGLAS I.
Publication type:
Article
Oncogenic c-terminal cyclin D1 (CCND1) mutations are enriched in endometrioid endometrial adenocarcinomas.
Published in:
PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0199688
By:
- Xu, Jia;
- Lin, Douglas I.
Publication type:
Article
TNS1-ALK Fusion in a Recurrent, Metastatic Uterine Mesenchymal Tumor Originally Diagnosed as Leiomyosarcoma.
Published in:
Acta Medica Academica, 2019, v. 48, n. 1, p. 116, doi. 10.5644/ama2006-124.248
By:
- Lee, Jessica;
- Singh, Arun;
- Ali, Siraj M.;
- Lin, Douglas I.;
- Klempner, Samuel J.
Publication type:
Article

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