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The rexinoid V-125 reduces tumor growth in preclinical models of breast and lung cancer.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04415-0
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- Publication type:
- Article
The Novel RXR Agonist MSU-42011 Differentially Regulates Gene Expression in Mammary Tumors of MMTV-Neu Mice.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4298, doi. 10.3390/ijms24054298
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- Article
T Cells and CDDO-Me Attenuate Immunosuppressive Activation of Human Melanoma-Conditioned Macrophages.
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- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.768753
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- Article
NRF2 as an Emerging Therapeutic Target.
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- Oxidative Medicine & Cellular Longevity, 2017, p. 1, doi. 10.1155/2017/8165458
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- Article
SYNTHETIC TRITERPENOIDS CAN PROTECT AGAINST TOXICITY WITHOUT REDUCING THE EFFICACY OF TREATMENT WITH CARBOPLATIN AND PACLITAXEL IN EXPERIMENTAL LUNG CANCER.
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- Dose-Response, 2014, v. 12, n. 1, p. 136, doi. 10.2203/dose-response.13-018.Liby
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- Article
A Synthetic Triterpenoid CDDO-Im Inhibits Tumorsphere Formation by Regulating Stem Cell Signaling Pathways in Triple-Negative Breast Cancer.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107616
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- Article
Proteomic Analysis Shows Synthetic Oleanane Triterpenoid Binds to mTOR.
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- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022862
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- Publication type:
- Article
Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription.
- Published in:
- PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005757
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- Publication type:
- Article
Retinoid X receptor agonist LG100268 modulates the immune microenvironment in preclinical breast cancer models.
- Published in:
- NPJ Breast Cancer, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41523-019-0135-5
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- Publication type:
- Article
The RXR Agonist MSU42011 Is Effective for the Treatment of Preclinical HER2+ Breast Cancer and Kras-Driven Lung Cancer.
- Published in:
- Cancers, 2021, v. 13, n. 19, p. 5004, doi. 10.3390/cancers13195004
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- Publication type:
- Article
The Bromodomain Inhibitor, INCB057643, Targets Both Cancer Cells and the Tumor Microenvironment in Two Preclinical Models of Pancreatic Cancer.
- Published in:
- Cancers, 2021, v. 13, n. 1, p. 96, doi. 10.3390/cancers13010096
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- Publication type:
- Article
CDDO-Me Alters the Tumor Microenvironment in Estrogen Receptor Negative Breast Cancer.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63482-x
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- Publication type:
- Article
Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46531-y
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- Publication type:
- Article
The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in Kras<sup>G12D</sup>; Pdx1-Cre (KC) mice.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43430-0
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- Publication type:
- Article
Editorial: Furthering precision medicine and cancer prevention through novel insights in molecular and chemical carcinogenesis.
- Published in:
- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1496908
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- Publication type:
- Article
The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the Kras<sup>G12D</sup>;Pdx1-Cre (KC) mouse model of pancreatic cancer.
- Published in:
- Carcinogenesis, 2016, v. 37, n. 12, p. 1170, doi. 10.1093/carcin/bgw099
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- Publication type:
- Article
Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis.
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- Carcinogenesis, 2015, v. 36, n. 7, p. 769, doi. 10.1093/carcin/bgv061
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- Publication type:
- Article
The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer.
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- Carcinogenesis, 2013, v. 34, n. 1, p. 199, doi. 10.1093/carcin/bgs319
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- Publication type:
- Article
Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.
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- Carcinogenesis, 2009, v. 30, n. 6, p. 1024, doi. 10.1093/carcin/bgp100
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- Publication type:
- Article
The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice.
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- 2009
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- Publication type:
- journal article
Genetic or Pharmacologic Amplification of Nrf2 Signaling Inhibits Acute Inflammatory Liver Injury in Mice.
- Published in:
- Toxicological Sciences, 2008, v. 104, n. 1, p. 218, doi. 10.1093/toxsci/kfn079
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- Publication type:
- Article
The Triterpenoid CDDO-Methyl Ester Reduces Tumor Burden, Reprograms the Immune Microenvironment, and Protects from Chemotherapy-Induced Toxicity in a Preclinical Mouse Model of Established Lung Cancer.
- Published in:
- Antioxidants, 2024, v. 13, n. 6, p. 621, doi. 10.3390/antiox13060621
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- Publication type:
- Article
The Triterpenoid CDDO-Methyl Ester Redirects Macrophage Polarization and Reduces Lung Tumor Burden in a Nrf2-Dependent Manner.
- Published in:
- Antioxidants, 2023, v. 12, n. 1, p. 116, doi. 10.3390/antiox12010116
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- Publication type:
- Article
Sustained, local delivery of the PARP inhibitor talazoparib prevents the development of mammary gland hyperplasia in Brca1-deficient mice.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79663-7
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- Publication type:
- Article
The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-79260-8
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- Publication type:
- Article
CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages.
- Published in:
- PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149600
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- Publication type:
- Article
Synthetic oleanane triterpenoids enhance blood brain barrier integrity and improve survival in experimental cerebral malaria.
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- Malaria Journal, 2017, v. 16, p. 1, doi. 10.1186/s12936-017-2109-0
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- Publication type:
- Article
Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34131-1
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- Publication type:
- Article
The BRD4 Inhibitor I-BET-762 Reduces HO-1 Expression in Macrophages and the Pancreas of Mice.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 18, p. 9985, doi. 10.3390/ijms25189985
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- Publication type:
- Article
KEAP1 -Mutant Lung Cancers Weaken Anti-Tumor Immunity and Promote an M2-like Macrophage Phenotype.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3510, doi. 10.3390/ijms25063510
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- Publication type:
- Article
NRF2 and cancer: the good, the bad and the importance of context.
- Published in:
- Nature Reviews Cancer, 2012, v. 12, n. 8, p. 564, doi. 10.1038/nrc3278
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- Article
Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.
- Published in:
- Nature Reviews Cancer, 2007, v. 7, n. 5, p. 357, doi. 10.1038/nrc2129
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- Article