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Mechanisms of Age-Related Cognitive Change and Targets for Intervention: Epigenetics.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 7, p. 741, doi. 10.1093/gerona/gls110
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- Article
Mechanisms of age-related cognitive change and targets for intervention: epigenetics.
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- 2012
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- Publication type:
- journal article
Cdk5: One of the links between senile plaques and neurofibrillary tangles?
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- Journal of Alzheimer's Disease, 2003, v. 5, n. 2, p. 127, doi. 10.3233/JAD-2003-5207
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- Article
Reelin and Cyclin-Dependent Kinase 5-Dependent Signals Cooperate in Regulating Neuronal Migration and Synaptic Transmission.
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- Journal of Neuroscience, 2004, v. 24, n. 8, p. 1897, doi. 10.1523/JNEUROSCI.4084-03.2004
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- Article
Cyclin-Dependent Kinase 5 Phosphorylates the N-Terminal Domain of the Postsynaptic Density Protein PSD-95 in Neurons.
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- Journal of Neuroscience, 2004, v. 24, n. 4, p. 865, doi. 10.1523/JNEUROSCI.4582-03.2004
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- Article
Control of Cortical Neuron Migration and Layering: Cell and Non Cell-Autonomous Effects of p35.
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- Journal of Neuroscience, 2004, v. 24, n. 2, p. 576, doi. 10.1523/JNEUROSCI.4529-03.2004
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- Article
Partial Rescue of the p35-/- Brain Phenotype by Low Expression of a Neuronal-Specific Enolase p25 Transgene.
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- Journal of Neuroscience, 2003, v. 23, n. 7, p. 2769, doi. 10.1523/JNEUROSCI.23-07-02769.2003
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- Article
Lithium protects against ApoE4 mediated calcium dysregulation and mitochondrial dysfunction and cell damage in iPSCs from a sporadic Alzheimer's disease patient.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082765
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- Article
Multi‐polygenic score model informs the genetic basis of heterogeneity in Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079231
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- Article
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071948
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- Article
Multi‐polygenic score model informs the genetic basis of heterogeneity in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079231
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- Publication type:
- Article
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071948
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- Article
Gamma frequency sensory stimulation prevents brain atrophy, improves sleep and memory in probable mild Alzheimer's patients.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054218
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- Article
A novel PU.1 inhibitor for the treatment of Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.052667
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- Article
F1‐07‐04: USING HUMAN IPSC MODELS TO PROBE TREM2 FUNCTION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P189, doi. 10.1016/j.jalz.2019.06.4396
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- Article
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.
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- Journal of Clinical Investigation, 2014, v. 124, n. 3, p. 981, doi. 10.1172/JCI72723
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- Article
A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory.
- Published in:
- eLife, 2016, p. 1
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- Article
How MicroRNAs Are Involved in Splitting the Mind.
- Published in:
- 2016
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- Publication type:
- journal article
Histone deacetylases in memory and cognition.
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- Science Signaling, 2014, v. 7, n. 355, p. 1, doi. 10.1126/scisignal.aaa0069
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- Article
S3-04-03: CDK5 and Aβ production
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- 2008
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- Abstract
P1-416: APP processing and cell cycle reentry signaling pathways are involved in p25/cdk5-mediated neurodegeneration
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- 2006
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- Abstract
S5-03-05: Symposia session
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- 2006
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- Abstract
P1-416: APP processing and cell cycle reentry signaling pathways are involved in p25/cdk5-mediated neurodegeneration
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- 2006
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- Publication type:
- Abstract
S5-03-05: Symposia session
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- 2006
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- Publication type:
- Abstract
14-3-3e is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome.
- Published in:
- Nature Genetics, 2003, v. 34, n. 3, p. 274, doi. 10.1038/ng1169
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- Article
Linking Cell Cycle Reentry and DNA Damage in Neurodegeneration.
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- Annals of the New York Academy of Sciences, 2009, v. 1170, p. 674, doi. 10.1111/j.1749-6632.2009.04105.x
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- Article
P35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5.
- Published in:
- Nature, 1994, v. 371, n. 6496, p. 419, doi. 10.1038/371419a0
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- Article
A DECADE OF CDK5.
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- Nature Reviews Molecular Cell Biology, 2001, v. 2, n. 10, p. 749, doi. 10.1038/35096019
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- Article
APP processing is regulated by cytoplasmic phosphorylation.
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- Journal of Cell Biology, 2003, v. 163, n. 1, p. 83, doi. 10.1083/jcb.200301115
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- Article
Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46478-3
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- Article
Targeting p35/Cdk5 Signalling via CIP-Peptide Promotes Angiogenesis in Hypoxia.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075538
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- Article
Cdk5 Is Required for Memory Function and Hippocampal Plasticity via the cAMP Signaling Pathway.
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- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025735
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- Article
Cognitive Function in Health and Disease: The Role of Epigenetic Mechanisms.
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- Neurodegenerative Diseases, 2012, v. 10, n. 1-4, p. 191, doi. 10.1159/000334602
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- Article
Mechanisms of DNA damage‐mediated neurotoxicity in neurodegenerative disease.
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- EMBO Reports, 2022, v. 23, n. 6, p. 1, doi. 10.15252/embr.202154217
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- Article
On the resilience of remote traumatic memories against exposure therapy-mediated attenuation.
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- EMBO Reports, 2014, v. 15, n. 8, p. 853, doi. 10.15252/embr.201438913
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- Article
Life is a journey: a genetic look at neocortical development.
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- 2002
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- Publication type:
- journal article
Three decades of Cdk5.
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- Journal of Biomedical Science, 2021, v. 28, n. 1, p. 1, doi. 10.1186/s12929-021-00774-y
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- Article
Profiling DNA break sites and transcriptional changes in response to contextual fear learning.
- Published in:
- PLoS ONE, 2021, v. 16, n. 7, p. 1, doi. 10.1371/journal.pone.0249691
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- Article
Callosal axon guidance defects in p35<sup>−/−</sup> mice.
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- Journal of Comparative Neurology, 1999, v. 415, n. 2, p. 218, doi. 10.1002/(SICI)1096-9861(19991213)415:2<218::AID-CNE6>3.0.CO;2-F
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- Article
A novel disruption of cortical development in p35<sup>−/−</sup> mice distinct from reeler.
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- Journal of Comparative Neurology, 1998, v. 395, n. 4, p. 510, doi. 10.1002/(SICI)1096-9861(19980615)395:4<510::AID-CNE7>3.0.CO;2-4
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- Publication type:
- Article
Centrosome Motility Is Essential for Initial Axon Formation in the Neocortex.
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- Journal of Neuroscience, 2010, v. 30, n. 31, p. 10391, doi. 10.1523/JNEUROSCI.0381-10.2010
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- Publication type:
- Article
Neuronal Morphogenesis Is Regulated by the Interplay between Cyclin-Dependent Kinase 5 and the Ubiquitin Ligase Mind Bomb 1.
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- Journal of Neuroscience, 2007, v. 27, n. 35, p. 9503, doi. 10.1523/JNEUROSCI.1408-07.2007
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- Article
p25/Cyclin-Dependent Kinase 5 Induces Production and Intraneuronal Accumulation of Amyloid Ißn Vivo.
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- Journal of Neuroscience, 2006, v. 26, n. 41, p. 10536, doi. 10.1523/JNEUROSCI.3133-06.2006
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- Publication type:
- Article
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.
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- EMBO Journal, 2007, v. 26, n. 13, p. 3169, doi. 10.1038/sj.emboj.7601758
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- Article
Editorial.
- Published in:
- NeuroSignals (Karger AG), 2003, v. 12, n. 4/5, p. 163, doi. 10.1159/000074616
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- Article
Cyclin-Dependent Kinase 5 and Neuronal Migration in the Neocortex.
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- NeuroSignals (Karger AG), 2003, v. 12, n. 4/5, p. 173, doi. 10.1159/000074618
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- Publication type:
- Article
Cognitive enhancement: A molecular memory booster.
- Published in:
- Nature, 2011, v. 469, n. 7331, p. 474, doi. 10.1038/469474a
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- Article
A novel pathway regulates memory and plasticity via SIRT1 and miR-134.
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- Nature, 2010, v. 466, n. 7310, p. 1105, doi. 10.1038/nature09271
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- Publication type:
- Article
Driving fast-spiking cells induces gamma rhythm and controls sensory responses.
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- Nature, 2009, v. 459, n. 7247, p. 663, doi. 10.1038/nature08002
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- Article
HDAC2 negatively regulates memory formation and synaptic plasticity.
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- Nature, 2009, v. 459, n. 7243, p. 55, doi. 10.1038/nature07925
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- Article